National Healthcare Quality and Disparities Report
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Search All Research Studies
Topics
- Children/Adolescents (1)
- Diabetes (1)
- Diagnostic Safety and Quality (1)
- Disparities (1)
- Emergency Department (1)
- Evidence-Based Practice (1)
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- (-) Human Immunodeficiency Virus (HIV) (11)
- Implementation (1)
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- Vulnerable Populations (1)
- Women (1)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 11 of 11 Research Studies DisplayedBradford W, Akselrod H, Bassler J
Hospitalization is a missed opportunity for HIV screening, pre-exposure prophylaxis, and treatment.
This multisite, retrospective cohort study of hospitalized patients with opioid use disorder with infectious complications of injection drug use looked at rates of HIV screening, pre-exposure prophylaxis, and treatment among these patients. The authors included 322 patients, with most (300) now known to have HIV. Of those, only 2 had a documented discussion of PrEP, while only 1 was prescribed PrEP on discharge. Among the 22 people with HIV (PWH), only 13 had a viral load collected during admission of whom all were viremic and 10 were successfully linked to care post-discharge. Both groups had high rates of readmission, Medicaid or uninsured status, and unstable housing.
AHRQ-funded; HS013852.
Citation: Bradford W, Akselrod H, Bassler J .
Hospitalization is a missed opportunity for HIV screening, pre-exposure prophylaxis, and treatment.
Addict Sci Clin Pract 2024 Mar 26; 19(1):22. doi: 10.1186/s13722-024-00451-z..
Keywords: Human Immunodeficiency Virus (HIV), Screening, Prevention, Inpatient Care
Lentz C, Iribarren S, Giguere R
Broaching the topic of HIV self-testing with potential sexual partners among men and transgender women who have sex with men in New York and Puerto Rico.
This randomized controlled trial examined whether access to free HIV self-testing (ST) kits had an impact on use of condoms during anal intercourse for 272 transgender women and men who have sex with men in New York City and San Juan, Puerto Rico. The trial included 136 persons in an intervention group and 136 persons in a control group. The intervention group had 32% fewer condomless anal intercourse (CAI) encounters- with the New York City group being statistically significant. In San Juan the results were non-significant, but two hurricanes may have impacted results in unmeasured ways.
AHRQ-funded; HS026383.
Citation: Lentz C, Iribarren S, Giguere R .
Broaching the topic of HIV self-testing with potential sexual partners among men and transgender women who have sex with men in New York and Puerto Rico.
AIDS Behav 2020 Nov;24(11):3033-43. doi: 10.1007/s10461-020-02851-z..
Keywords: Human Immunodeficiency Virus (HIV), Infectious Diseases, Sexual Health, Prevention, Screening
Skaathun B, Pho MT, Pollack HA
Comparison of effectiveness and cost for different HIV screening strategies implemented at large urban medical centre in the United States.
This analysis compared the effectiveness and cost of three HIV testing strategies in a high HIV burden area in the U.S. in identifying new HIV infections. The investigators performed a cost analysis comparing three HIV testing strategies in Chicago: (1) routine screening (RS) in an inpatient and outpatient setting, (2) modified partner services (MPS) among networks of the recently HIV infected and diagnosed, and (3) a respondent drive sampling (RDS)-based social network (SN) approach targeting young African-American men who have sex with men.
AHRQ-funded; HS000084.
Citation: Skaathun B, Pho MT, Pollack HA .
Comparison of effectiveness and cost for different HIV screening strategies implemented at large urban medical centre in the United States.
J Int AIDS Soc 2020 Oct;23(10):e25554. doi: 10.1002/jia2.25554..
Keywords: Human Immunodeficiency Virus (HIV), Screening, Healthcare Costs, Prevention, Infectious Diseases
Rael CT, Giguere R, Lopez-Rios J
Transgender women's experiences using a home HIV-testing kit for partner-testing.
HIV partner-testing (PT) may represent a unique and empowering HIV prevention strategy for groups that face structural and institutional barriers to HIV testing and care, including transgender women. In this study, the investigators reported on in-depth interviews (IDIs) with transgender women who used HIV self-test kits for three months to screen potential sexual partners in a randomized controlled trial that took place in New York City and San Juan, Puerto Rico.
AHRQ-funded; HS026383.
Citation: Rael CT, Giguere R, Lopez-Rios J .
Transgender women's experiences using a home HIV-testing kit for partner-testing.
AIDS Behav 2020 Sep;24(9):2732-41. doi: 10.1007/s10461-020-02829-x..
Keywords: Human Immunodeficiency Virus (HIV), Prevention, Vulnerable Populations, Women, Patient Experience, Screening
Brault MA, Spiegelman D, Abdool Karim SS
Integrating and interpreting findings from the latest treatment as prevention trials.
This paper examined findings from some 2018-2019 international studies assessing the effectiveness of reducing HIV incidence by expanding HIV testing, linkage to HIV treatment, and helping persons living with HIV adhere to their medications (called the 90-90-90 strategy). A number of these “treatment as prevention” (TasP) tests had complex results. The studies examined included the TasP/ANRS 12249 study in South Africa, the SEARCH study in Kenya and Uganda, and one comparison (arms A to C) of the HPtn 071 (PopART) study in South Africa and Zambia as well as the Botswana Ya Tsie study. All but the Botswana Ya Tsie study and the second comparison (arms B to C) of PopART did not demonstrate a community impact on HIV incidence. But those two studies indicated significant (30%) reductions in HIV incidence in the intervention communities.
AHRQ-funded; HS023000.
Citation: Brault MA, Spiegelman D, Abdool Karim SS .
Integrating and interpreting findings from the latest treatment as prevention trials.
Curr HIV/AIDS Rep 2020 Jun;17(3):249-58. doi: 10.1007/s11904-020-00492-4..
Keywords: Human Immunodeficiency Virus (HIV), Prevention, Implementation, Medication, Screening
Brault MA, Spiegelman D, Hargreaves J
Treatment as prevention: concepts and challenges for reducing HIV incidence.
This paper reviews the results and lessons learned from four large-scale HIV antiretroviral therapy (ART) clinical trials that were held in sub-Saharan Africa to reduce HIV transmission. These trials used treatment as prevention (TasP) to improve overall health and protect HIV-uninfected sexual partners from infection. There were seemingly inconsistent findings in the major TasP trials held in South African, Kenya, Uganda, Botswana, and Zambia. The review highlighted implementation challenges and identified approaches to optimize programs and incentivize uptake and engagement in HIV testing and ART-based care.
AHRQ-funded; HS023000.
Citation: Brault MA, Spiegelman D, Hargreaves J .
Treatment as prevention: concepts and challenges for reducing HIV incidence.
J Acquir Immune Defic Syndr 2019 Dec 1;82 Suppl 2:S104-s12. doi: 10.1097/qai.0000000000002168..
Keywords: Human Immunodeficiency Virus (HIV), Prevention, Infectious Diseases, Public Health, Screening
Tracer H, Jasmin W
AHRQ Author: Tracer H
Screening for HIV Infection and Preexposure Prophylaxis for the Prevention of HIV Infection.
This case study provides questions and answers on the topic of screening for HIV infection and preexposure prophylaxis for the prevention of HIV infection.
AHRQ-authored.
Citation: Tracer H, Jasmin W .
Screening for HIV Infection and Preexposure Prophylaxis for the Prevention of HIV Infection.
Am Fam Physician 2019 Nov 15;100(10):637-38..
Keywords: U.S. Preventive Services Task Force (USPSTF), Human Immunodeficiency Virus (HIV), Screening, Prevention
Chou R, Dana T, Grusing S
Screening for HIV infection in asymptomatic, nonpregnant adolescents and adults: updated evidence report and systematic review for the US Preventive Services Task Force.
Untreated HIV infection can result in significant morbidity, mortality, and HIV transmission. A 2012 review for the US Preventive Services Task Force (USPSTF) found antiretroviral therapy (ART) associated with improved clinical outcomes and decreased transmission risk in persons with CD4 cell counts less than 500/mm3. The objective of this study was to update the 2012 review on HIV screening to inform the USPSTF.
AHRQ-funded; 290201500009I.
Citation: Chou R, Dana T, Grusing S .
Screening for HIV infection in asymptomatic, nonpregnant adolescents and adults: updated evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2019 Jun 18;321(23):2337-48. doi: 10.1001/jama.2019.2592..
Keywords: U.S. Preventive Services Task Force (USPSTF), Children/Adolescents, Human Immunodeficiency Virus (HIV), Screening, Prevention, Evidence-Based Practice
Wingood GM, Lambert D, Renfro T
A multilevel intervention with African American churches to enhance adoption of point-of-care HIV and diabetes testing, 2014-2018.
This article describes a multilevel intervention to enhance the adoption of point-of-care HIV and diabetes testing at church health fairs in Atlanta, GA. Church leaders viewed a video and subsequently conducted social activities that support testing; a third of the churches involved hosted HIV and diabetes health fairs and resulted in an increase in attendees receiving HIV or diabetes testing. The authors conclude that this implementation science approach could reduce HIV and diabetes disparities among African Americans.
AHRQ-funded; HS022059.
Citation: Wingood GM, Lambert D, Renfro T .
A multilevel intervention with African American churches to enhance adoption of point-of-care HIV and diabetes testing, 2014-2018.
Am J Public Health 2019 Feb;109(S2):S141-s44. doi: 10.2105/ajph.2019.304990..
Keywords: Diabetes, Human Immunodeficiency Virus (HIV), Prevention, Racial and Ethnic Minorities, Disparities, Screening
Haukoos JS, Lyons MS, Rothman RE
The evolving landscape of HIV screening in the emergency department.
This article is a summary of two studies that appear in the same edition of the journal. The two studies describe the value of using targeted vs. non-targeted screening for HIV in emergency departments (EDs). New diagnosis rates were relatively small, which suggested that the use of targeted screening may be need to be refined more in terms of selection criteria.
AHRQ-funded; HS021749.
Citation: Haukoos JS, Lyons MS, Rothman RE .
The evolving landscape of HIV screening in the emergency department.
Ann Emerg Med 2018 Jul;72(1):54-56. doi: 10.1016/j.annemergmed.2018.01.041..
Keywords: Diagnostic Safety and Quality, Emergency Department, Human Immunodeficiency Virus (HIV), Prevention, Screening
Gaines TL, Caldwell JT, Ford CL
Relationship between a Centers for Disease Control and Prevention expanded HIV testing initiative and past-year testing by race/ethnicity: a multilevel analysis of the Behavioral Risk Factor Surveillance System.
The Centers for Disease Control and Prevention's (CDC) expanded testing initiative (ETI) aims to bolster HIV testing among populations disproportionately affected by the HIV epidemic by providing additional funding to health departments serving these communities. Controlling for individual- and state-level characteristics, ETI participation was independently and positively associated with past-year testing, but this association varied by race/ethnicity.
AHRQ-funded; HS022811.
Citation: Gaines TL, Caldwell JT, Ford CL .
Relationship between a Centers for Disease Control and Prevention expanded HIV testing initiative and past-year testing by race/ethnicity: a multilevel analysis of the Behavioral Risk Factor Surveillance System.
AIDS Care 2016;28(5):554-60. doi: 10.1080/09540121.2015.1131968.
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Keywords: Human Immunodeficiency Virus (HIV), Screening, Prevention, Racial and Ethnic Minorities