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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 2 of 2 Research Studies DisplayedMalone S, McKay VR, Krucylak C
A cluster randomized stepped-wedge trial to de-implement unnecessary post-operative antibiotics in children: the optimizing perioperative antibiotic in children (OPerAtiC) trial.
This paper describes an upcoming clinical trial to determine best strategies to de-implement inappropriate antibiotic use in pediatric post-operative surgical cases deemed low risk for infection. This study will provide important information on the impact of two potential strategies while assessing important clinical outcomes.
AHRQ-funded; HS026742.
Citation: Malone S, McKay VR, Krucylak C .
A cluster randomized stepped-wedge trial to de-implement unnecessary post-operative antibiotics in children: the optimizing perioperative antibiotic in children (OPerAtiC) trial.
Implement Sci 2021 Mar 19;16(1):29. doi: 10.1186/s13012-021-01096-1..
Keywords: Children/Adolescents, Antimicrobial Stewardship, Antibiotics, Medication, Surgery
Jones TW, Fino N, Olson J
The impact of beta-lactam allergy labels on hospitalized children.
Investigators sought to determine the impact of beta-lactam allergy labels in hospitalized children with regards to clinical and economic outcomes. Subjects were pediatric patients hospitalized at Intermountain Healthcare facilities from 2007 to 2017 who received one or more 1 dose of an antibiotic during their admission. The researchers found that patients with beta-lactam allergy received broader-spectrum antibiotics and experienced higher antibiotic costs than nonallergic controls. However, there were no differences in the length of stay, readmission rates, or total number of days of antibiotics between allergic and nonallergic patients.
AHRQ-funded; HS023320.
Citation: Jones TW, Fino N, Olson J .
The impact of beta-lactam allergy labels on hospitalized children.
Infect Control Hosp Epidemiol 2021 Mar;42(3):318-24. doi: 10.1017/ice.2020.424..
Keywords: Children/Adolescents, Antibiotics, Medication, Antimicrobial Stewardship