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AHRQ Research Studies Date
Topics
- Adverse Drug Events (ADE) (1)
- Alcohol Use (1)
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- Sepsis (1)
- Skin Conditions (5)
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 22 of 22 Research Studies DisplayedNarla S, Silverberg JI
The inpatient burden and comorbidities of pyoderma gangrenosum in adults in the United States.
The objective of this study was to determine the prevalence, predictors, outcomes, and costs of hospitalization for pyoderma gangrenosum (PG) in United States adults. Data from the 2002-2012 National Inpatient Sample were analyzed. Findings showed that PG admissions were more likely at teaching and medium or large hospitals. The majority of inpatients with PG were classified with minor or moderate likelihood of dying, but moderate and major loss of function. PG was associated with numerous other health disorders. This study demonstrated a substantial and increasing inpatient burden of PG in the United States, with considerable disability and mortality risk, multiple comorbid health disorders, and costs.
AHRQ-funded; HS023011.
Citation: Narla S, Silverberg JI .
The inpatient burden and comorbidities of pyoderma gangrenosum in adults in the United States.
Arch Dermatol Res 2021 May;313(4):245-53. doi: 10.1007/s00403-020-02098-7..
Keywords: Healthcare Cost and Utilization Project (HCUP), Skin Conditions, Injuries and Wounds, Hospitalization, Healthcare Costs
Kaltenborn Z, Paul K, Kirsch JD
Super fragmented: a nationally representative cross-sectional study exploring the fragmentation of inpatient care among super-utilizers.
Researchers sought to determine the prevalence of super-utilizers who receive fragmented care across different hospitals and to describe associated risks, costs, and health outcomes. Using HCUP data, they found that inpatient care fragmentation was common among super-utilizers and disproportionately affected vulnerable populations. It was associated with high yearly costs and a decreased probability of correctly identifying super-utilizers.
AHRQ-funded; HS026732.
Citation: Kaltenborn Z, Paul K, Kirsch JD .
Super fragmented: a nationally representative cross-sectional study exploring the fragmentation of inpatient care among super-utilizers.
BMC Health Serv Res 2021 Apr 14;21(1):338. doi: 10.1186/s12913-021-06323-5..
Keywords: Healthcare Cost and Utilization Project (HCUP), Healthcare Costs, Hospitalization
Bourne DS, Davis BS, Gigli KH
Economic analysis of mandated protocolized sepsis care in New York hospitals.
Investigators evaluated the effects of the 2013 New York State sepsis regulations on the costs of care for patients hospitalized with sepsis. They found that mandated protocolized sepsis care was not associated with significant changes in hospital costs in patients hospitalized with sepsis in New York State.
AHRQ-funded; HS025146.
Citation: Bourne DS, Davis BS, Gigli KH .
Economic analysis of mandated protocolized sepsis care in New York hospitals.
Crit Care Med 2020 Oct;48(10):1411-18. doi: 10.1097/ccm.0000000000004514..
Keywords: Healthcare Cost and Utilization Project (HCUP), Sepsis, Healthcare Costs, Hospitalization, Hospitals
Patel KR, Singam V, Rastogi S
Association of vitiligo with hospitalization for mental health disorders in US adults.
The goal of this study was to examine the relationship between vitiligo and mental-health hospitalizations in the US using data from the National Inpatient Sample. Prevalence of hospitalization for mental-health disorders, length of stay (LOS), and cost of care were examined for patients with vitiligo in comparison with those without vitiligo. Hospitalization for mental-health disorders occurred more commonly in those with vitiligo. Vitiligo patients who were hospitalized with any mental-health disorder had higher LOS as well as cost of inpatient care.
AHRQ-funded; HS023011.
Citation: Patel KR, Singam V, Rastogi S .
Association of vitiligo with hospitalization for mental health disorders in US adults.
J Eur Acad Dermatol Venereol 2019 Jan;33(1):191-97. doi: 10.1111/jdv.15255..
Keywords: Healthcare Cost and Utilization Project (HCUP), Healthcare Costs, Hospitalization, Behavioral Health, Skin Conditions
Kwa MC, Silverberg JI, Ardalan K
Inpatient burden of juvenile dermatomyositis among children in the United States.
The purpose of this study was to determine the prevalence and risk factors for hospitalization with juvenile dermatomyositis and assess inpatient burden of juvenile dermatomyositis (JDM). The study authors found that JDM contributes to both increased length of hospitalization and inpatient cost of care. Non-Medicaid government insurance was associated with higher rates of hospitalization for JDM while Hispanic and other non-white racial/ethnic groups demonstrated increased length of stay and cost of care.
AHRQ-funded; HS023011.
Citation: Kwa MC, Silverberg JI, Ardalan K .
Inpatient burden of juvenile dermatomyositis among children in the United States.
Pediatr Rheumatol Online J 2018 Nov 13;16(1):70. doi: 10.1186/s12969-018-0286-1..
Keywords: Children/Adolescents, Healthcare Costs, Healthcare Cost and Utilization Project (HCUP), Hospitalization, Skin Conditions
Henke RM, Karaca Z, Gibson TB
AHRQ Author: Karaca Z, Wong HS
Medicare Advantage penetration and hospital costs before and after the Affordable Care Act.
This study investigated the relationship between Medicare Advantage (MA) program growth and inpatient hospital costs and utilization before and after the ACA. Its results suggest that MA enrollment growth is associated with diminished spillover reductions in hospital admission costs after the ACA. Researchers did not observe a strong relationship between MA enrollment and inpatient days per enrollee
AHRQ-authored; AHRQ-funded; 290201300002C.
Citation: Henke RM, Karaca Z, Gibson TB .
Medicare Advantage penetration and hospital costs before and after the Affordable Care Act.
Med Care 2018 Apr;56(4):321-28. doi: 10.1097/mlr.0000000000000885.
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Keywords: Healthcare Costs, Policy, Healthcare Cost and Utilization Project (HCUP), Hospitalization, Medicare
Hsu DY, Shinkai K, Silverberg JI
Epidemiology of eczema herpeticum in hospitalized U.S. children: analysis of a nationwide cohort.
This study used data from the Nationwide Inpatient Sample 2002-2012 to determine incidence, risk factors, comorbidities, costs, length of stay, and mortality in hospitalized children with Eczema herpeticum (EH). A higher risk was associated with younger age and non-white ethnicity (Asian in particular). However there was less frequency of hospitalization associated with lower income quartiles. The mortality incidence was 0.1%.
AHRQ-funded; HS023011.
Citation: Hsu DY, Shinkai K, Silverberg JI .
Epidemiology of eczema herpeticum in hospitalized U.S. children: analysis of a nationwide cohort.
J Invest Dermatol 2018 Feb;138(2):265-72. doi: 10.1016/j.jid.2017.08.039..
Keywords: Children/Adolescents, Healthcare Cost and Utilization Project (HCUP), Healthcare Costs, Hospitalization, Skin Conditions
Spector WD, Limcangco R, Furukawa MF
AHRQ Author: Spector WD, Limcangco R, Furukawa MF, Encinosa WE
The marginal costs of adverse drug events associated with exposures to anticoagulants and hypoglycemic agents during hospitalization.
The researchers estimated the marginal cost of care associated with anticoagulants and hypoglycemic agents for adults in 5 patient groups during their hospital stay and the total annual ADE costs for all patients exposed to these drugs during their stay. The 2013 hospital cost estimates for adverse drug events associated with anticoagulants and hypoglycemic agents were >$2.5 billion for each drug class.
AHRQ-authored.
Citation: Spector WD, Limcangco R, Furukawa MF .
The marginal costs of adverse drug events associated with exposures to anticoagulants and hypoglycemic agents during hospitalization.
Med Care 2017 Sep;55(9):856-63. doi: 10.1097/mlr.0000000000000780.
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Keywords: Healthcare Cost and Utilization Project (HCUP), Adverse Drug Events (ADE), Blood Thinners, Hospitalization, Healthcare Costs
Leshem E, Tate JE, Steiner CA
AHRQ Author: Steiner. CA
National estimates of reductions in acute gastroenteritis-related hospitalizations and associated costs in US children after implementation of rotavirus vaccines.
The study compared acute gastroenteritis (AGE)-related hospitalization rates among children <5 years of age during the pre-rotavirus vaccine (2000-2006) and post-rotavirus vaccine (2008-2013) periods to estimate national reductions in AGE-related hospitalizations and associated costs.
AHRQ-authored
Citation: Leshem E, Tate JE, Steiner CA .
National estimates of reductions in acute gastroenteritis-related hospitalizations and associated costs in US children after implementation of rotavirus vaccines.
J Pediatric Infect Dis Soc 2017 Aug 17;7(3):257-60. doi: 10.1093/jpids/pix057..
Keywords: Children/Adolescents, Healthcare Costs, Healthcare Cost and Utilization Project (HCUP), Hospitalization, Vaccination
Narla S, Hsu DY, Thyssen JP
Inpatient financial burden of atopic dermatitis in the United States.
Little is known about the inpatient burden of atopic dermatitis (AD). The researchers sought to determine some risk factors and financial-burden of hospitalizations for AD in the US. They found that the high prevalence of hospitalization resulted in total inpatient costs of $8,288,083 per-year for adults and $3,333,868 per-year for children. In conclusion, there is a substantial inpatient financial-burden of AD in the US.
AHRQ-funded; HS023011.
Citation: Narla S, Hsu DY, Thyssen JP .
Inpatient financial burden of atopic dermatitis in the United States.
J Invest Dermatol 2017 Jul;137(7):1461-67. doi: 10.1016/j.jid.2017.02.975.
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Keywords: Healthcare Cost and Utilization Project (HCUP), Skin Conditions, Healthcare Costs, Hospitalization
Hsu DY, Gordon K, Silverberg JI
Serious infections in hospitalized patients with psoriasis in the United States.
The researchers sought to determine rates and predictors of serious infections in hospitalized psoriasis patients and quantify costs of care, length of stay, and mortality. Among patients with psoriasis, rates of serious infections increased over all time intervals analyzed and were significantly higher compared with those without psoriasis across all time intervals.
AHRQ-funded; HS023011.
Citation: Hsu DY, Gordon K, Silverberg JI .
Serious infections in hospitalized patients with psoriasis in the United States.
J Am Acad Dermatol 2016 Aug;75(2):287-96. doi: 10.1016/j.jaad.2016.04.005..
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Keywords: Healthcare Cost and Utilization Project (HCUP), Hospitalization, Healthcare Costs, Inpatient Care
Hsu D, Brieva J, Silverberg JI
Costs of care for hospitalization for pemphigus in the United States.
The purpose of this study was to determine the incidence of and risk factors for hospitalization with pemphigus and cost of care. It concluded that there is a significant inpatient burden for pemphigus in the United States. Moreover, there appear to be racial/ethnic and health care disparities with respect to pemphigus, such that poor, nonwhite, and/or uninsured or underinsured patients have higher odds of hospitalization.
AHRQ-funded; HS023011.
Citation: Hsu D, Brieva J, Silverberg JI .
Costs of care for hospitalization for pemphigus in the United States.
JAMA Dermatol 2016 Jun;152(6):645-54. doi: 10.1001/jamadermatol.2015.5240..
Keywords: Healthcare Costs, Hospitalization, Disparities, Healthcare Cost and Utilization Project (HCUP), Risk
Hellinger FJ
AHRQ Author: Hellinger FJ
Hospital use by persons with HIV in the 21st century: a 5-state study.
The purpose of this study was to determine whether reductions in hospital utilization observed immediately after the availability of highly active antiretroviral therapy (between 1995 and 2000) have persisted into the 21st century. It found that the total number of hospitalizations by persons with HIV in the 5 study states fell by one third between 2000 and 2013 even though the number of persons living with HIV increased by >50%.
AHRQ-authored.
Citation: Hellinger FJ .
Hospital use by persons with HIV in the 21st century: a 5-state study.
Med Care 2016 Jun;54(6):639-44. doi: 10.1097/mlr.0000000000000526.
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Keywords: Healthcare Cost and Utilization Project (HCUP), Human Immunodeficiency Virus (HIV), Hospitalization, Healthcare Costs
Heslin KC, Elixhauser A, Steiner CA
AHRQ Author: Heslin KC, Elixhauser A, Steiner CA
Identifying in-patient costs attributable to the clinical sequelae and comorbidities of alcoholic liver disease in a national hospital database.
The aim of this study was to compare the average costs of hospitalizations with alcoholic liver disease (ALD) and the costs of hospitalizations with other alcohol-related diagnoses that do not involve the liver. It found that costs of hospital care for patients with ALD are higher than those for patients with other alcohol-related diagnoses.
AHRQ-authored.
Citation: Heslin KC, Elixhauser A, Steiner CA .
Identifying in-patient costs attributable to the clinical sequelae and comorbidities of alcoholic liver disease in a national hospital database.
Addiction 2016 May;112(5):782-91. doi: 10.1111/add.13702.
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Keywords: Healthcare Cost and Utilization Project (HCUP), Alcohol Use, Healthcare Costs, Nutrition, Hospitalization
Skinner HG, Coffey R, Jones J
AHRQ Author: Heslin KC, Moy E
The effects of multiple chronic conditions on hospitalization costs and utilization for ambulatory care sensitive conditions in the United States: a nationally representative cross-sectional study.
A purpose of this study was to evaluate how multiple chronic conditions relate to inpatient hospitalization costs. It found that compared with costs for patients with 0 or 1 chronic condition, hospitalization costs per stay for overall ambulatory care sensitive conditions were 19 percent higher for those with 2 or 3 , 32 percent higher for those with 4 or 5, and 31 percent higher for those with 6+ conditions.
AHRQ-authored; AHRQ-funded; 290201300002C.
Citation: Skinner HG, Coffey R, Jones J .
The effects of multiple chronic conditions on hospitalization costs and utilization for ambulatory care sensitive conditions in the United States: a nationally representative cross-sectional study.
BMC Health Serv Res 2016 Mar 1;16:77. doi: 10.1186/s12913-016-1304-y.
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Keywords: Healthcare Cost and Utilization Project (HCUP), Chronic Conditions, Hospitalization, Healthcare Utilization, Healthcare Costs
Smith MW, Friedman B, Karaca Z
AHRQ Author: Friedman B, Karaca Z, Wong HS
Predicting inpatient hospital payments in the United States: a retrospective analysis.
The researchers evaluated whether payment-to-charge ratios (PCRs) can be predicted for hospitals in States that do not provide detailed financial data. They found that inpatient payments can be estimated with modest accuracy for community hospital stays funded by Medicare, Medicaid, and private insurance.
AHRQ-authored.
Citation: Smith MW, Friedman B, Karaca Z .
Predicting inpatient hospital payments in the United States: a retrospective analysis.
BMC Health Serv Res 2015 Sep 10;15(1):372. doi: 10.1186/s12913-015-1040-8..
Keywords: Healthcare Cost and Utilization Project (HCUP), Inpatient Care, Healthcare Costs, Hospitalization
Duseja R, Bardach NS, Lin GA
Revisit rates and associated costs after an emergency department encounter: a multistate analysis.
This study describes revisit rates, variation in revisit rates by diagnosis and state, and associated costs. It found that revisits after an index ED encounter are more frequent than previously reported, in part because many occur outside the index institution. Among ED patients in Florida, more resources are spent on revisits than on index ED visits.
AHRQ-funded; HS020667.
Citation: Duseja R, Bardach NS, Lin GA .
Revisit rates and associated costs after an emergency department encounter: a multistate analysis.
Ann Intern Med 2015 Jun 2;162(11):750-6. doi: 10.7326/m14-1616..
Keywords: Healthcare Cost and Utilization Project (HCUP), Healthcare Costs, Emergency Department, Hospitalization, Hospital Readmissions
Simeone RM, Oster ME, Cassell CH
AHRQ Author: Gray DT
Pediatric inpatient hospital resource use for congenital heart defects.
The authors sought to estimate healthcare costs for infants, children, and adolescents with congenital heart defects (CHDs). Using the 2009 Healthcare Cost and Utilization Project Kids' Inpatient Database (KID), they found that hospitalizations for children with CHDs have disproportionately high hospital costs compared with other pediatric hospitalizations, and the 17% of hospitalizations with critical CHD diagnoses accounted for 27% of CHD hospital costs.
AHRQ-authored.
Citation: Simeone RM, Oster ME, Cassell CH .
Pediatric inpatient hospital resource use for congenital heart defects.
Birth Defects Res A Clin Mol Teratol 2014 Dec;100(12):934-43. doi: 10.1002/bdra.23262.
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Keywords: Cardiovascular Conditions, Children/Adolescents, Healthcare Costs, Healthcare Cost and Utilization Project (HCUP), Hospitalization
Trudnak Fowler T, Fairbrother G, Owens P
AHRQ Author: Owens P
Trends in complicated newborn hospital stays & costs, 2002-2009: implications for the future.
The researchers used HCUP data to examine trends from 2002 through 2009 in complicated newborn hospital stays, and to explore the relationship between expected sources of payment and reasons for hospitalizations. They concluded that state Medicaid programs are paying for an increasing proportion of births and costly complicated births, and they suggested that policies to prevent common birth complications have the potential to reduce costs for public programs and improve birth outcomes.
AHRQ-authored.
Citation: Trudnak Fowler T, Fairbrother G, Owens P .
Trends in complicated newborn hospital stays & costs, 2002-2009: implications for the future.
Medicare Medicaid Res Rev 2014;4(4). doi: 10.5600/mmrr.004.04.a03.
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Keywords: Healthcare Costs, Healthcare Cost and Utilization Project (HCUP), Hospitalization, Newborns/Infants
Levit KR, Friedman B, Wong HS
AHRQ Author: Friedman B, Wong HS
Estimating inpatient hospital prices from state administrative data and hospital financial reports.
The researchers developed a tool for estimating hospital-specific inpatient prices for major payers. They found that hospital prices can be reasonably estimated for 10 geographically diverse states. They further found that estimated prices compare well with Medicare, MarketScan private insurance, and the Medical Expenditure Panel Survey prices for major payers, given limitations of each dataset.
AHRQ-authored; AHRQ-funded.
Citation: Levit KR, Friedman B, Wong HS .
Estimating inpatient hospital prices from state administrative data and hospital financial reports.
Health Serv Res 2013 Oct;48(5):1779-97. doi: 10.1111/1475-6773.12065.
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Keywords: Healthcare Costs, Healthcare Cost and Utilization Project (HCUP), Hospitalization, Medical Expenditure Panel Survey (MEPS)
Steiner CA, Friedman B
AHRQ Author: Steiner CA, Friedman B
Hospital utilization, costs, and mortality for adults with multiple chronic conditions, Nationwide Inpatient Sample, 2009.
The investigators provided a national estimate across all payers of the distribution and cost of selected chronic conditions for hospitalized adults in 2009, stratified by demographic characteristics. They found that there were approximately 28 million adult discharges from US hospitals other than those related to pregnancy and maternity; 39% had 2 to 3 multiple chronic conditions (MCC), and 33% had 4 or more. They concluded that their descriptive analysis of multipayer inpatient data provides a robust national view of the substantial use and costs among adults hospitalized with MCC.
AHRQ-authored.
Citation: Steiner CA, Friedman B .
Hospital utilization, costs, and mortality for adults with multiple chronic conditions, Nationwide Inpatient Sample, 2009.
Prev Chronic Dis 2013 Apr 25;10:E62. doi: 10.5888/pcd10.120292.
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Keywords: Chronic Conditions, Healthcare Costs, Healthcare Cost and Utilization Project (HCUP), Hospitalization, Mortality
Braithwaite S, Friedman B, Mutter R
AHRQ Author: Friedman B, Mutter R
Microsimulation of financial impact of demand surge on hospitals: the H1N1 influenza pandemic of fall 2009.
Microsimulation was used to assess the financial impact on hospitals of a surge in influenza admissions in advance of the H1N1 pandemic in the fall of 2009 with the goal of estimating net income and losses of a response of filling unused hospital bed capacity proportionately and postponing elective admissions. They concluded that aggregate and distributional results did not suggest that a policy of promising additional financial compensation to hospitals in anticipation of the surge in flu cases was necessary.
AHRQ-authored.
Citation: Braithwaite S, Friedman B, Mutter R .
Microsimulation of financial impact of demand surge on hospitals: the H1N1 influenza pandemic of fall 2009.
Health Serv Res 2013 Apr;48(2 Pt 2):735-52. doi: 10.1111/1475-6773.12041.
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Keywords: Healthcare Costs, Healthcare Cost and Utilization Project (HCUP), Hospitalization, Influenza