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Search All Research Studies
AHRQ Research Studies Date
Topics
- Adverse Drug Events (ADE) (2)
- Adverse Events (2)
- Centers for Education and Research on Therapeutics (CERTs) (1)
- Clinical Decision Support (CDS) (2)
- Comparative Effectiveness (1)
- Diabetes (1)
- Electronic Health Records (EHRs) (3)
- Genetics (1)
- (-) Health Information Technology (HIT) (9)
- Home Healthcare (1)
- Medical Errors (2)
- (-) Medication (9)
- Opioids (1)
- Patient Safety (4)
- Patient Self-Management (1)
- Primary Care (1)
- Registries (1)
- Shared Decision Making (2)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 9 of 9 Research Studies DisplayedSlight SP, Berner ES, Glanter W
Meaningful use of electronic health records: experiences from the field and future opportunities.
AHRQ-sponsored Centers for Education and Research in Therapeutics (CERTs) critically examined the impact of the MU policy relating to the use of medications and jointly developed recommendations to help inform future HIT policy. The conclusion was that although MU has stimulated adoption of EHRs, its effects on quality and safety remain uncertain. Stakeholders felt that MU requirements should be more flexible and recognize that integrated models may achieve information-sharing goals in alternate ways.
AHRQ-funded.
Citation: Slight SP, Berner ES, Glanter W .
Meaningful use of electronic health records: experiences from the field and future opportunities.
JMIR Med Inform 2015 Sep 18;3(3):e30. doi: 10.2196/medinform.4457..
Keywords: Centers for Education and Research on Therapeutics (CERTs), Electronic Health Records (EHRs), Health Information Technology (HIT), Medication
Nuckols TK, Smith-Spangler C, Morton SC
The effectiveness of computerized order entry at reducing preventable adverse drug events and medication errors in hospital settings: a systematic review and meta-analysis.
The primary objective of this systematic review and meta-analysis study was to quantitatively assess the effectiveness of computerized provider order entry (CPOE) at reducing preventable adverse drug events (pADE). It found that CPOE is associated with cutting in half the number of pADEs. Medication errors were also about half as common with CPOE.
AHRQ-funded; HS017954
Citation: Nuckols TK, Smith-Spangler C, Morton SC .
The effectiveness of computerized order entry at reducing preventable adverse drug events and medication errors in hospital settings: a systematic review and meta-analysis.
Syst Rev. 2014 Jun 4;3:56. doi: 10.1186/2046-4053-3-56..
Keywords: Health Information Technology (HIT), Adverse Drug Events (ADE), Adverse Events, Medical Errors, Medication, Patient Safety
Overby CL, Devine EB, Abernethy N
Making pharmacogenomic-based prescribing alerts more effective: a scenario-based pilot study with physicians.
This pilot study explored the communication effectiveness and clinical impact of using a prototype clinical decision support (CDS) system embedded in an electronic health record (EHR) to deliver pharmacogenomic (PGx) information to physicians. The proportion of physicians that saw a relative advantage to using PGx-CDS was 83 percent at the start and 94 percent at the conclusion of our study.
AHRQ-funded; HS014739.
Citation: Overby CL, Devine EB, Abernethy N .
Making pharmacogenomic-based prescribing alerts more effective: a scenario-based pilot study with physicians.
J Biomed Inform 2015 Jun;55:249-59. doi: 10.1016/j.jbi.2015.04.011..
Keywords: Clinical Decision Support (CDS), Electronic Health Records (EHRs), Health Information Technology (HIT), Medication, Patient Safety
Ayvaz S, Horn J, Hassanzadeh O
Toward a complete dataset of drug-drug interaction information from publicly available sources.
The researchers combined all the publicly available sources of potential drug-drug interaction information using a common data model after conducting a comprehensive and broad search. They examined the overlap between and across the data sources. Their analysis determined that there was little overlap and that there is heterogeneity between the information provided by each source.
AHRQ-funded; HS019461.
Citation: Ayvaz S, Horn J, Hassanzadeh O .
Toward a complete dataset of drug-drug interaction information from publicly available sources.
J Biomed Inform 2015 Jun;55:206-17. doi: 10.1016/j.jbi.2015.04.006..
Keywords: Medication, Patient Safety, Registries, Health Information Technology (HIT)
Burgess JF, Jones EA, Morgan JR
Capsule commentary on Tannenbaum et al., nudging physician prescription decisions by partitioning the order set: results of a vignette-based study.
Users of computerized provider order entry (CPOE)s employ a variety of “shortcuts” to increase efficiency and reduce search costs. The authors comment on a study suggesting that new ordering could be a shortcut for signaling which choices are “common or appropriate”. They argue that future research on inappropriate use should grapple directly with when and why providers employ shortcuts.
AHRQ-funded; HS022242.
Citation: Burgess JF, Jones EA, Morgan JR .
Capsule commentary on Tannenbaum et al., nudging physician prescription decisions by partitioning the order set: results of a vignette-based study.
J Gen Intern Med 2015 Mar;30(3):343. doi: 10.1007/s11606-014-3095-3..
Keywords: Health Information Technology (HIT), Shared Decision Making, Medication
Tannenbaum D, Doctor JN, Persell SD
Nudging physician prescription decisions by partitioning the order set: results of a vignette-based study.
The purpose of this study was to examine whether the grouping of menu items systematically affects prescribing practices among primary care providers. It found that provider treatment choice appears to be influenced by the grouping of menu options, suggesting that the layout of EHR order sets is not an arbitrary exercise.
AHRQ-funded; RC4 AG039115 (NIA/AHRQ).
Citation: Tannenbaum D, Doctor JN, Persell SD .
Nudging physician prescription decisions by partitioning the order set: results of a vignette-based study.
J Gen Intern Med 2015 Mar;30(3):298-304. doi: 10.1007/s11606-014-3051-2..
Keywords: Electronic Health Records (EHRs), Primary Care, Clinical Decision Support (CDS), Health Information Technology (HIT), Medication
Samwald M, Minarro Gimenez JA, Boyce RD
Pharmacogenomic knowledge representation, reasoning and genome-based clinical decision support based on OWL 2 DL ontologies.
The authors developed Web Ontology Language (OWL) ontologies and automated reasoning methodologies to meet various goals such as providing a simple and concise formalism for representing pharmacogenomic knowledge. Their ontology-based framework can be used to represent, organize and reason over the growing wealth of pharmacogenomic knowledge, as well as to identify errors, inconsistencies and insufficient definitions in source data sets or individual patient data.
AHRQ-funded; HS019461.
Citation: Samwald M, Minarro Gimenez JA, Boyce RD .
Pharmacogenomic knowledge representation, reasoning and genome-based clinical decision support based on OWL 2 DL ontologies.
BMC Med Inform Decis Mak 2015 Feb 22;15:12. doi: 10.1186/s12911-015-0130-1..
Keywords: Comparative Effectiveness, Health Information Technology (HIT), Shared Decision Making, Medication, Genetics
Topaz M, Seger DL, Lai K
High override rate for opioid drug-allergy interaction alerts: current trends and recommendations for future.
This paper examined trends in drug-allergy interaction (DAI) alert overrides for opioid medications - the most commonly triggered alerts in the computerized provider order entry (CPOE). Allergic reactions included a high proportion of non-immune mediated opioid reactions. The DAI alert override rate was high for immune-mediated and life-threatening reactions. Exact allergy-medication matches were overridden less frequently compared to non-exact matches within allergy groups.
AHRQ-funded; HS022728.
Citation: Topaz M, Seger DL, Lai K .
High override rate for opioid drug-allergy interaction alerts: current trends and recommendations for future.
Stud Health Technol Inform 2015;216:242-6.
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Keywords: Opioids, Adverse Drug Events (ADE), Adverse Events, Health Information Technology (HIT), Medication, Patient Safety, Medical Errors
Casper GR, Flatley Brennan P, Perreault JO
vizHOME--a context-based home assessment: preliminary implications for informatics.
The focus of this paper is on the first phase of the vizHOME study, specifically on the exploration and documentation of the individual’s performance of self-management tasks including such things as medication management and use of a monitoring device. The researchers learned from the participants that while the tools may perform satisfactorily in usability assessment, they may not meet the needs of many users.
AHRQ-funded; HS022548.
Citation: Casper GR, Flatley Brennan P, Perreault JO .
vizHOME--a context-based home assessment: preliminary implications for informatics.
Stud Health Technol Inform 2015;216:842-6..
Keywords: Diabetes, Patient Self-Management, Home Healthcare, Health Information Technology (HIT), Medication