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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 2 of 2 Research Studies DisplayedMoin T, Schmittdiel JA, Flory JH
Review of metformin use for type 2 diabetes prevention.
This evidence review summarizes the use of metform for type 2 diabetes prevention. Articles published between 1998 and 2017 were analyzed, and forty articles met inclusion criteria. Metformin was associated with reduced relative risk of type 2 diabetes, with the strongest evidence for use with those higher-risk patients. These patients are aged 60 years or more, BMI greater or equal to 35, and women with histories of gestational diabetes. It was also deemed cost-effective in 11 economic analyses.
AHRQ-funded; HS023898.
Citation: Moin T, Schmittdiel JA, Flory JH .
Review of metformin use for type 2 diabetes prevention.
Am J Prev Med 2018 Oct;55(4):565-74. doi: 10.1016/j.amepre.2018.04.038..
Keywords: Diabetes, Evidence-Based Practice, Medication, Prevention
Raebel MA, Ellis JL, Schroeder EB
Intensification of antihyperglycemic therapy among patients with incident diabetes: a Surveillance Prevention and Management of Diabetes Mellitus (SUPREME-DM) study.
The aim of this study was to characterize antihyperglycemic intensification during the first year after initiating oral antihyperglycemic therapy among adult patients with incident diabetes. The researchers found that 43.5 percent of patients with diabetes had treatment intensified within 1 year of starting antihyperglycemic medication. HbA1c of less than 7 percent was achieved in a very high proportion of patients (65.1 percent).
AHRQ-funded; HS019859
Citation: Raebel MA, Ellis JL, Schroeder EB .
Intensification of antihyperglycemic therapy among patients with incident diabetes: a Surveillance Prevention and Management of Diabetes Mellitus (SUPREME-DM) study.
Pharmacoepidemiol Drug Saf, 2014 Jul;23(7):699-710. doi: 10.1002/pds.3610..
Keywords: Diabetes, Prevention, Medication