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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 4 of 4 Research Studies DisplayedMills J, Harding MC
AHRQ Author: Mills J
Screening for obstructive sleep apnea in adults.
This Putting Prevention into Practice case study was created to increase understanding of the USPSTF final recommendation on screening for obstructive sleep apnea (OSA) in adults. A case study was presented using a 41-year-old man with a history of class 1 obesity but was otherwise feeling well. The patient has an uncle who was recently diagnosed with OSA, and the patient has some questions. Three multiple-choice questions are presented regarding USPSTF recommendations whether to screen for OSA for that patient.
AHRQ-authored.
Citation: Mills J, Harding MC .
Screening for obstructive sleep apnea in adults.
Am Fam Physician 2023 Mar;107(3):297-98.
Keywords: U.S. Preventive Services Task Force (USPSTF), Sleep Problems, Guidelines, Prevention, Evidence-Based Practice, Case Study
Feltnerl. C, Wallace IF, Aymes S
Screening for obstructive sleep apnea in adults: updated evidence report and systematic review for the US Preventive Services Task Force.
The purpose of this study was to examine the evidence on screening for obstructive sleep apnea (OSA) in asymptomatic adults or those with unrecognized OSA symptoms to inform the U.S. Preventive Services Task Force. The researchers utilized data from PubMed/MEDLINE, Cochrane Library, Embase, and trial registries through August 23, 2021 and surveillance data through September 23, 2022. The main outcomes were accuracy, excessive daytime sleepiness, sleep-related and general health-related quality of life (QOL), and harms. Eighty-six studies were included (N = 11,051), researchers finding that no study directly compared screening with no screening. Five studies evaluating the accuracy of other screening tools provided inconsistent results. When compared with inactive control, positive airway pressure was associated with a significant improvement in ESS score from baseline, sleep-related QOL, and general health-related QOL measured by the 36-Item Short Form Health Survey (SF-36) mental health component summary score change, and SF-36 physical health component summary score change. When compared with controls, utilization of mandibular advancement devices was also related with a significantly larger ESS score change. Reporting of other health outcomes was scarce; no trial included in the study found significant benefit related with treatment on mortality, cardiovascular events, or motor vehicle crashes. In 3 systematic reviews, positive airway pressure was significantly associated with reduced blood pressure; but the difference was relatively small. The researchers concluded that the accuracy and clinical usefulness of OSA screening tools was unclear.
Citation: Feltnerl. C, Wallace IF, Aymes S .
Screening for obstructive sleep apnea in adults: updated evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2022 Nov 15;328(19):1951-71. doi: 10.1001/jama.2022.18357..
Keywords: U.S. Preventive Services Task Force (USPSTF), Sleep Problems, Screening, Evidence-Based Practice, Prevention
McNellis RJ, Thomas S
AHRQ Author: McNellis RJ
Screening for obstructive sleep apnea in adults.
This case study involves a 52-year-old white man who presents to your office for a preventive health visit. He is overweight and has a history of hypertension and hyperlipidemia, which are stable and well controlled with medication. The study poses three multiple choice questions together with the U.S. Preventive Services Task Force recommendations and related background information.
AHRQ-authored.
Citation: McNellis RJ, Thomas S .
Screening for obstructive sleep apnea in adults.
Am Fam Physician 2017 Jul 15;96(2):123-24.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Sleep Problems, Screening, Evidence-Based Practice, Case Study, Guidelines
Jonas DE, Amick HR, Feltner C
Screening for obstructive sleep apnea in adults: evidence report and systematic review for the US Preventive Services Task Force.
The effectiveness of stool-based colorectal cancer (CRC) screening is contingent on colonoscopy completion in patients with an abnormal fecal immunochemical test (FIT). This study found that FIT positive patients never referred to gastroenterology or who missed their appointment after referrals were more likely to have comorbid conditions and documented illicit substance use compared with patients who completed a colonoscopy.
AHRQ-funded; 290201200015I.
Citation: Jonas DE, Amick HR, Feltner C .
Screening for obstructive sleep apnea in adults: evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2017 Jan 24;317(4):415-33. doi: 10.1001/jama.2016.19635.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Screening, Sleep Problems, Evidence-Based Practice, Respiratory Conditions