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Topics
- Cardiovascular Conditions (1)
- (-) Centers for Education and Research on Therapeutics (CERTs) (12)
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- Comparative Effectiveness (2)
- Diabetes (1)
- Education: Patient and Caregiver (1)
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- Orthopedics (1)
- Pain (1)
- Patient-Centered Healthcare (1)
- Patient-Centered Outcomes Research (3)
- Patient Adherence/Compliance (1)
- Patient and Family Engagement (1)
- Patient Safety (1)
- Pregnancy (1)
- Risk (2)
- Rural Health (1)
- Shared Decision Making (1)
- Surgery (3)
- Vitamins and Supplements (1)
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 12 of 12 Research Studies DisplayedMoza R, Truong DT, Lambert LM
Poor weight recovery between stage 1 palliation and hospital discharge for infants with single ventricle physiology: an analysis of the NPC-QIC Phase II dataset.
The purpose of this study was to investigate change in weight-for-age z-scores (WAZ) and risk factors for impaired weight gain between stage 1 palliation (S1P) for single ventricle physiology and discharge. Data from the National Pediatric Cardiology Quality Improvement Collaborative Phase II database was analysed. Findings showed that nearly all infants lost weight after S1P, with little recovery by hospital discharge. At discharge, three-quarters of the infants were at-risk for impaired weight gain or had failure to thrive. Most risk factors associated with change in WAZ were unmodifiable or surrogates of disease severity.
AHRQ-funded; HS021114.
Citation: Moza R, Truong DT, Lambert LM .
Poor weight recovery between stage 1 palliation and hospital discharge for infants with single ventricle physiology: an analysis of the NPC-QIC Phase II dataset.
J Pediatr 2021 Jul;234:20-26.e2. doi: 10.1016/j.jpeds.2021.03.035..
Keywords: Newborns/Infants, Centers for Education and Research on Therapeutics (CERTs), Heart Disease and Health, Cardiovascular Conditions, Health Status, Risk
Singh JA, Ramachandaran R
Does rural residence impact total ankle arthroplasty utilization and outcomes?
The objective of this study was to compare total ankle arthroplasty (TAA) utilization and outcomes by patient residence. It demonstrated an absence of any evidence of rural-urban differences in TAA outcomes. The rural-urban differences in TAA utilization noted in 2003 were no longer significant in 2011.
AHRQ-funded; HS021110.
Citation: Singh JA, Ramachandaran R .
Does rural residence impact total ankle arthroplasty utilization and outcomes?
Clin Rheumatol 2016 Feb;35(2):381-6. doi: 10.1007/s10067-015-2908-z.
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Keywords: Centers for Education and Research on Therapeutics (CERTs), Rural Health, Surgery, Patient-Centered Outcomes Research, Healthcare Utilization
Reynolds RJ, Vazquez AI, Srinivasasainagendra V
Serum urate gene associations with incident gout, measured in the Framingham Heart Study, are modified by renal disease and not by body mass index.
The researchers hypothesized that serum urate-associated SNPs, individually or collectively, interact with BMI and renal disease to contribute to risk of incident gout. They measured the incidence of gout and associated comorbidities using the original and offspring cohorts of the Framingham Heart Study. They demonstrated that minor alleles of rs1106766 (intergenic, INHBC) were negatively associated with the risk of incident gout in subjects without renal disease, but not for individuals with renal disease.
AHRQ-funded; HS021110.
Citation: Reynolds RJ, Vazquez AI, Srinivasasainagendra V .
Serum urate gene associations with incident gout, measured in the Framingham Heart Study, are modified by renal disease and not by body mass index.
Rheumatol Int 2016 Feb;36(2):263-70. doi: 10.1007/s00296-015-3364-4.
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Keywords: Centers for Education and Research on Therapeutics (CERTs), Evidence-Based Practice, Genetics, Risk, Obesity
Singh JA, Ramachandran R
Time trends in total ankle arthroplasty in the USA: a study of the National Inpatient Sample.
The objective of this study was to assess the time trends in utilization, clinical characteristics, and outcomes of patients undergoing total ankle arthroplasty (TAA) in the USA. It concluded that the utilization rate of TAA increased rapidly in the USA from 1998 to 2010, but post-arthroplasty mortality rate was stable. Underlying diagnosis and medical comorbidity changed over time and both can impact outcomes after TAA.
AHRQ-funded; HS021110.
Citation: Singh JA, Ramachandran R .
Time trends in total ankle arthroplasty in the USA: a study of the National Inpatient Sample.
Clin Rheumatol 2016 Jan;35(1):239-45. doi: 10.1007/s10067-014-2703-2.
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Keywords: Healthcare Cost and Utilization Project (HCUP), Centers for Education and Research on Therapeutics (CERTs), Surgery, Patient-Centered Outcomes Research, Healthcare Utilization
Slight SP, Berner ES, Glanter W
Meaningful use of electronic health records: experiences from the field and future opportunities.
AHRQ-sponsored Centers for Education and Research in Therapeutics (CERTs) critically examined the impact of the MU policy relating to the use of medications and jointly developed recommendations to help inform future HIT policy. The conclusion was that although MU has stimulated adoption of EHRs, its effects on quality and safety remain uncertain. Stakeholders felt that MU requirements should be more flexible and recognize that integrated models may achieve information-sharing goals in alternate ways.
AHRQ-funded.
Citation: Slight SP, Berner ES, Glanter W .
Meaningful use of electronic health records: experiences from the field and future opportunities.
JMIR Med Inform 2015 Sep 18;3(3):e30. doi: 10.2196/medinform.4457..
Keywords: Centers for Education and Research on Therapeutics (CERTs), Electronic Health Records (EHRs), Health Information Technology (HIT), Medication
Singh JA, Qu H, Yazdany J
Barriers to medication decision making in women with lupus nephritis: a formative study using nominal group technique.
The researchers assessed the perspectives of women with lupus nephritis on barriers to medication decision making. The most salient perceived barriers, as indicated by percent-weighted votes assigned, were known/anticipated side effects (15.6 percent), medication expense/ability to afford medications (8.2 percent), and the fear that the medication could cause other diseases (7.8 percent).
AHRQ-funded; HS021110.
Citation: Singh JA, Qu H, Yazdany J .
Barriers to medication decision making in women with lupus nephritis: a formative study using nominal group technique.
J Rheumatol 2015 Sep;42(9):1616-23. doi: 10.3899/jrheum.150168.
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Keywords: Centers for Education and Research on Therapeutics (CERTs), Shared Decision Making, Education: Patient and Caregiver, Medication, Patient and Family Engagement
Singh JA, Bharat A, Edwards NL
An internet survey of common treatments used by patients with gout including cherry extract and juice and other dietary supplements.
The researchers aimed to assess the prevalent use of cherry extract/products and other supplements by gout patients and the characteristics of these patients. They found that almost 50 percent of gout patients used cherry extract, juice or other supplements. Twenty-seven percent of men and 18 percent of women reported using other food items/natural supplements.
AHRQ-funded; HS021110.
Citation: Singh JA, Bharat A, Edwards NL .
An internet survey of common treatments used by patients with gout including cherry extract and juice and other dietary supplements.
J Clin Rheumatol 2015 Jun;21(4):225-6. doi: 10.1097/rhu.0000000000000246..
Keywords: Vitamins and Supplements, Comparative Effectiveness, Centers for Education and Research on Therapeutics (CERTs)
Przytula K, Bailey SC, Galanter WL
A primary care, electronic health record-based strategy to promote safe drug use: study protocol for a randomized controlled trial.
The researchers designed a health literacy-informed, electronic health record based strategy for promoting safe and effective prescription medication use among English and Spanish-speaking patients with diabetes mellitus. This paper provides an overview of their intervention, summarizes evaluation activities, and discusses the sustainability and potential dissemination of their novel strategy.
AHRQ-funded; HS021093.
Citation: Przytula K, Bailey SC, Galanter WL .
A primary care, electronic health record-based strategy to promote safe drug use: study protocol for a randomized controlled trial.
Trials 2015 Jan 27;16:17. doi: 10.1186/s13063-014-0524-x..
Keywords: Centers for Education and Research on Therapeutics (CERTs), Electronic Health Records (EHRs), Diabetes, Medication, Patient Safety
Shahid H, Singh JA
Investigational drugs for hyperuricemia.
This review discusses ten new drugs in preclinical and early clinical trials for hyperuricemia, their mechanisms of action and available results. The researchers believe that growing knowledge about the urate transporters in the kidney has advanced knowledge of pathophysiology of hyperuricemia and led to the development of several new potential treatment options.
AHRQ-funded; HS021110.
Citation: Shahid H, Singh JA .
Investigational drugs for hyperuricemia.
Expert Opin Investig Drugs 2015;24(8):1013-30. doi: 10.1517/13543784.2015.1051617..
Keywords: Centers for Education and Research on Therapeutics (CERTs), Comparative Effectiveness, Medication
McMullen CK, Safford MM, Bosworth HB
Patient-centered priorities for improving medication management and adherence.
The goal of the workshop was to identify and prioritize opportunities to advance PCMM by convening diverse stakeholders involved in prescribing and/or medication taking. A major conclusion was that engaging multiple stakeholders in setting a patient-centered research agenda and broadening the scope of adherence interventions to include other aspects of medication management resulted in priorities outside the traditional scope of adherence research.
AHRQ-funded; HS021093; HS021094; HS021107.
Citation: McMullen CK, Safford MM, Bosworth HB .
Patient-centered priorities for improving medication management and adherence.
Patient Educ Couns 2015 Jan;98(1):102-10. doi: 10.1016/j.pec.2014.09.015..
Keywords: Centers for Education and Research on Therapeutics (CERTs), Chronic Conditions, Medication, Patient Adherence/Compliance, Patient-Centered Healthcare
Singh JA, Lewallen DG
Are outcomes after total knee arthroplasty worsening over time? A time-trends study of activity limitation and pain outcomes.
The authors examined whether function and pain outcomes of patients undergoing primary total knee arthroplasty (TKA) are changing over time. Using Mayo Clinic Total Joint Registry data, they found that patient-reported function and pain outcomes after primary TKA have worsened over the study period 1993-95 to 2002-05; this time-trend is independent of changes in preoperative pain/limitation and certain patient characteristics.
AHRQ-funded; HS021110.
Citation: Singh JA, Lewallen DG .
Are outcomes after total knee arthroplasty worsening over time? A time-trends study of activity limitation and pain outcomes.
BMC Musculoskelet Disord 2014 Dec 17;15:440. doi: 10.1186/1471-2474-15-440.
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Keywords: Centers for Education and Research on Therapeutics (CERTs), Orthopedics, Pain, Patient-Centered Outcomes Research, Surgery
Dublin S, Johnson KE, Walker RL
Trends in elective labor induction for six United States health plans, 2001-2007.
The authors sought to describe trends in labor induction, including elective induction, from 2001 to 2007 for six U.S. health plans and to examine the validity of induction measures derived from birth certificate and health plan data. They found that induction prevalence rose from 28% in 2001 to 32% in 2005, then declined to 29% in 2007, with the trend being similar for subgroups by parity and gestational age. Elective induction prevalence varied considerably across plans.
AHRQ-funded; HS016955.
Citation: Dublin S, Johnson KE, Walker RL .
Trends in elective labor induction for six United States health plans, 2001-2007.
J Womens Health 2014 Nov;23(11):904-11. doi: 10.1089/jwh.2014.4779.
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Keywords: Centers for Education and Research on Therapeutics (CERTs), Health Insurance, Labor and Delivery, Pregnancy, Women