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Search All Research Studies
Topics
- Adverse Drug Events (ADE) (1)
- Adverse Events (1)
- (-) Comparative Effectiveness (8)
- (-) Diabetes (8)
- Healthcare Costs (1)
- Hospitalization (1)
- Labor and Delivery (1)
- Maternal Care (1)
- Medication (4)
- Newborns/Infants (1)
- Obesity: Weight Management (1)
- Outcomes (3)
- Patient-Centered Healthcare (1)
- Patient-Centered Outcomes Research (2)
- Patient and Family Engagement (1)
- Pregnancy (1)
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- Women (1)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 8 of 8 Research Studies DisplayedKuo YF, Chen NW, Baillargeon J
Potentially preventable hospitalizations in Medicare patients with diabetes: a comparison of primary care provided by nurse practitioners versus physicians.
The researchers compared the rates of potentially preventable hospitalizations in older diabetic patients who received primary care from nurse practitioners (NPs) only versus those who received care from primary care physicians only. Using potentially preventable hospitalizations as a quality indicator, they found that primary care provided by NPs was at least comparable with that provided by generalist physicians.
AHRQ-funded; HS020642; HS022134.
Citation: Kuo YF, Chen NW, Baillargeon J .
Potentially preventable hospitalizations in Medicare patients with diabetes: a comparison of primary care provided by nurse practitioners versus physicians.
Med Care 2015 Sep;53(9):776-83. doi: 10.1097/mlr.0000000000000406..
Keywords: Hospitalization, Primary Care, Comparative Effectiveness, Diabetes
Schmittdiel JA, Desai J, Schroeder EB
Methods for engaging stakeholders in comparative effectiveness research: a patient-centered approach to improving diabetes care.
This article presents ways to engage stakeholders in comparative effectiveness research, including patient community surveys, stakeholder meetings with substantial patient representation, and patient stakeholder deciding votes in selecting pilot research topics. Researchers and health care leaders should continue to develop best-practices and strategies for increasing patient involvement in comparative effectiveness and delivery science research.
AHRQ-funded; HS022963; HS019859.
Citation: Schmittdiel JA, Desai J, Schroeder EB .
Methods for engaging stakeholders in comparative effectiveness research: a patient-centered approach to improving diabetes care.
Healthc (Amst) 2015 Jun;3(2):80-8. doi: 10.1016/j.hjdsi.2015.02.005.
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Keywords: Comparative Effectiveness, Diabetes, Patient-Centered Healthcare, Patient-Centered Outcomes Research, Patient and Family Engagement
Camelo Castillo W, Boggess K, Sturmer T
Association of adverse pregnancy outcomes with glyburide vs insulin in women with gestational diabetes.
The purpose of this study was to estimate the risks of adverse pregnancy outcomes among women receiving glyburide compared with insulin for the treatment of gestational diabetes mellitus (GDM) in a US population-based cohort. It found an association between glyburide (compared with insulin) and elevated risk of NICU admission, neonatal hypoglycemia, respiratory distress, birth injury, and large for gestational age in women with GDM.
AHRQ-funded; HS017950.
Citation: Camelo Castillo W, Boggess K, Sturmer T .
Association of adverse pregnancy outcomes with glyburide vs insulin in women with gestational diabetes.
JAMA Pediatr 2015 May;169(5):452-8. doi: 10.1001/jamapediatrics.2015.74..
Keywords: Adverse Drug Events (ADE), Adverse Events, Comparative Effectiveness, Diabetes, Labor and Delivery, Maternal Care, Medication, Newborns/Infants, Outcomes, Pregnancy, Women
Romanelli RJ, Chung S, Pu J
Comparative effectiveness of early versus delayed metformin in the treatment of type 2 diabetes.
The purpose of this study was to quantify the effectiveness of early versus delayed initiation of metformin monotherapy on glycemic control (measured by change in HbA1c) and weight modification (change in body mass index [BMI]). It found that treatment with metformin earlier in the course of type 2 diabetes is associated with better glycemic control, more pronounced weight reduction, and a lower risk for therapy intensification than delayed treatment.
AHRQ-funded; HS019815.
Citation: Romanelli RJ, Chung S, Pu J .
Comparative effectiveness of early versus delayed metformin in the treatment of type 2 diabetes.
Diabetes Res Clin Pract 2015 Apr;108(1):170-8. doi: 10.1016/j.diabres.2014.12.019..
Keywords: Diabetes, Medication, Comparative Effectiveness, Obesity: Weight Management, Outcomes
Bowen ME, Xuan L, Lingvay I
Random blood glucose: a robust risk factor for type 2 diabetes.
This study examined the association between random glucose values and undiagnosed diabetes and prediabetes. In a nationally representative sample of the U.S. population without diagnosed diabetes, the researchers found that a single random blood glucose value of at least 100 mg/dL (5.6 mmol/L) is strongly associated with undiagnosed diabetes and demonstrates a robust dose response.
AHRQ-funded; HS022418
Citation: Bowen ME, Xuan L, Lingvay I .
Random blood glucose: a robust risk factor for type 2 diabetes.
J Clin Endocrinol Metab. 2015 Apr;100(4):1503-10. doi: 10.1210/jc.2014-4116..
Keywords: Diabetes, Risk, Comparative Effectiveness
Prentice JC, Conlin PR, Gellad WF
Long-term outcomes of analogue insulin compared with NPH for patients with type 2 diabetes mellitus.
The researchers compared the effects of neutral protamine Hagedorn (NPH) and long-acting insulin analogues on long-term outcomes. They found no consistent difference in long-term health outcomes when comparing use of long-acting insulin analogues and NPH insulin. The higher cost of analogue insulin without demonstrable clinical benefit raises questions of its cost effectiveness in the treatment of patients with diabetes.
AHRQ-funded; HS019708.
Citation: Prentice JC, Conlin PR, Gellad WF .
Long-term outcomes of analogue insulin compared with NPH for patients with type 2 diabetes mellitus.
Am J Manag Care 2015 Mar;21(3):e235-43..
Keywords: Comparative Effectiveness, Diabetes, Healthcare Costs, Medication, Outcomes
Tan A, Holmes HM, Kuo YF
Coadministration of co-trimoxazole with sulfonylureas: hypoglycemia events and pattern of use.
This study assessed the prevalence of coadministration of co-trimoxazole with sulfonylureas and risk of subsequent emergency room (ER) visits for hypoglycemia among older patients with diabetes. It found that the coadministration of co-trimoxazole with sulfonylureas is associated with increased risk of hypoglycemia. Such coadministration is prevalent among older diabetic patients and varies substantially across U.S. geographic regions.
AHRQ-funded; HS022134.
Citation: Tan A, Holmes HM, Kuo YF .
Coadministration of co-trimoxazole with sulfonylureas: hypoglycemia events and pattern of use.
J Gerontol A Biol Sci Med Sci 2015 Feb;70(2):247-54. doi: 10.1093/gerona/glu072..
Keywords: Comparative Effectiveness, Patient-Centered Outcomes Research, Diabetes, Medication
Grijalva CG, Roumie CL, Murff HJ
The role of matching when adjusting for baseline differences in the outcome variable of comparative effectiveness studies.
The aim of this study was to evaluate performance of analytical strategies commonly used to adjust for baseline differences in continuous outcome variables for comparative effectiveness studies. It found that with increasing HbA1c baseline differences between groups, bias in effect estimates and suboptimal confidence interval coverage probabilities increased in all approaches. These issues were further compounded by measurement error. Matching on baseline HbA1c, substantially mitigated these issues.
AHRQ-funded; 2902010000161.
Citation: Grijalva CG, Roumie CL, Murff HJ .
The role of matching when adjusting for baseline differences in the outcome variable of comparative effectiveness studies.
J Comp Eff Res 2015;4(4):341-9. doi: 10.2217/cer.15.16..
Keywords: Comparative Effectiveness, Research Methodologies, Diabetes