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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 3 of 3 Research Studies DisplayedBurda BU, Holmer HK, Norris SL
Limitations of A Measurement Tool to Assess Systematic Reviews (AMSTAR) and suggestions for improvement.
A Measurement Tool to Assess Systematic Reviews (AMSTAR) is a commonly used tool to assess the quality of systematic reviews; however, modifications are needed to improve its usability, reliability, and validity. In this commentary, the authors summarize their experience and the experiences of others who have used AMSTAR and provide suggestions for its improvement.
AHRQ-funded; HS018500.
Citation: Burda BU, Holmer HK, Norris SL .
Limitations of A Measurement Tool to Assess Systematic Reviews (AMSTAR) and suggestions for improvement.
Syst Rev 2016 Apr 12;5:58. doi: 10.1186/s13643-016-0237-1.
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Keywords: Research Methodologies, Data, Evidence-Based Practice, Guidelines, Quality Measures
Gartlehner G, Dobrescu A, Evans TS
The predictive validity of quality of evidence grades for the stability of effect estimates was low: a meta-epidemiological study.
This study sought to determine the predictive validity of the U.S. Evidence-based Practice Center (EPC) approach to GRADE (Grading of Recommendations Assessment, Development and Evaluation). It concluded that the limited predictive validity of the EPC approach to GRADE seems to reflect a mismatch between expected and observed changes in treatment effects as bodies of evidence advance from insufficient to high quality of evidence.
AHRQ-funded; 290201200008I.
Citation: Gartlehner G, Dobrescu A, Evans TS .
The predictive validity of quality of evidence grades for the stability of effect estimates was low: a meta-epidemiological study.
J Clin Epidemiol 2016 Feb;70:52-60. doi: 10.1016/j.jclinepi.2015.08.018.
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Keywords: Evidence-Based Practice, Research Methodologies, Quality Measures
Berkman ND, Lohr KN, Ansari MT, et al.
AHRQ Author: Chang S
Grading the strength of a body of evidence when assessing health care interventions: an EPC update.
The purpose of this article is to revise the 2010 guidance on grading the strength of evidence (SOE) of the effectiveness of drugs, devices, and other preventive and therapeutic interventions produced by AHRQ’s Evidence-based Practice Center program. It concluded that no single approach for grading SOE suits all reviews, but a more consistent and transparent approach to reporting summary information will make reviews more useful.
AHRQ authored; AHRQ-funded 290200710056I
Citation: Berkman ND, Lohr KN, Ansari MT, et al..
Grading the strength of a body of evidence when assessing health care interventions: an EPC update.
J Clin Epidemiol. 2015 Nov;68(11):1312-24. doi: 10.1016/j.jclinepi.2014.11.023..
Keywords: Comparative Effectiveness, Evidence-Based Practice, Research Methodologies, Quality Measures