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Search All Research Studies
AHRQ Research Studies Date
Topics
- Adverse Events (5)
- Ambulatory Care and Surgery (2)
- Antibiotics (2)
- Antimicrobial Stewardship (2)
- Cardiovascular Conditions (2)
- Children/Adolescents (1)
- Comprehensive Unit-based Safety Program (CUSP) (1)
- Elderly (1)
- Electronic Health Records (EHRs) (3)
- (-) Healthcare-Associated Infections (HAIs) (15)
- Healthcare Costs (2)
- Health Information Technology (HIT) (4)
- Health Insurance (1)
- Heart Disease and Health (1)
- Hospitals (2)
- Infectious Diseases (3)
- Injuries and Wounds (7)
- Medicare (1)
- Medication (1)
- Obesity (1)
- Outcomes (1)
- Patient-Centered Outcomes Research (1)
- Patient Safety (11)
- Payment (3)
- Pneumonia (1)
- Prevention (4)
- Provider Performance (1)
- Public Health (1)
- Risk (1)
- Sepsis (1)
- (-) Surgery (15)
- Surveys on Patient Safety Culture (1)
- Telehealth (1)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 15 of 15 Research Studies DisplayedKline SE, Sanstead EC, Johnson JR
Cost-effectiveness of pre-operative Staphylococcus aureus screening and decolonization.
In this study, the investigators developed a decision analytic model to evaluate the impact of a preoperative Staphylococcus aureus decolonization bundle on surgical site infections (SSIs), health-care-associated costs (HCACs), and deaths due to SSI. The investigators predict that the treat-all strategy would be the most effective and cost-saving strategy for preventing SSIs. However, they concluded that because this strategy might select more extensively for mupirocin-resistant S. aureus and cause more medication adverse effects than the test-and-treat approach or the SOC, additional studies are needed to define its comparative benefits and harms.
AHRQ-funded; HS022912.
Citation: Kline SE, Sanstead EC, Johnson JR .
Cost-effectiveness of pre-operative Staphylococcus aureus screening and decolonization.
Infect Control Hosp Epidemiol 2018 Nov;39(11):1340-46. doi: 10.1017/ice.2018.228..
Keywords: Surgery, Antibiotics, Antimicrobial Stewardship, Healthcare-Associated Infections (HAIs), Infectious Diseases, Patient Safety, Prevention, Healthcare Costs
Colborn KL, Bronsert M, Amioka E
Identification of surgical site infections using electronic health record data.
The objective of this study was to develop an algorithm for identifying surgical site infections (SSIs) using independent variables from electronic health record data and outcomes from the American College of Surgeons National Surgical Quality Improvement Program to supplement manual chart review. The investigators concluded that they identified a model that accurately identified SSIs. They indicated that the framework presented can be easily implemented by other American College of Surgeons National Surgical Quality Improvement Program-participating hospitals to develop models for enhancing surveillance of SSIs.
AHRQ-funded; HS026019.
Citation: Colborn KL, Bronsert M, Amioka E .
Identification of surgical site infections using electronic health record data.
Am J Infect Control 2018 Nov;46(11):1230-35. doi: 10.1016/j.ajic.2018.05.011..
Keywords: Electronic Health Records (EHRs), Health Information Technology (HIT), Healthcare-Associated Infections (HAIs), Injuries and Wounds, Patient Safety, Surgery
Karavite DJ, Miller MW, Ramos MJ
User testing an information foraging tool for ambulatory surgical site infection surveillance.
Surveillance for surgical site infections (SSIs) after ambulatory surgery in children requires a detailed manual chart review to assess criteria defined by the National Health and Safety Network. Electronic health records (EHRs) impose an inefficient search process. Using text mining and business intelligence software, the authors developed an information foraging application, the SSI Workbench, to visually present which postsurgical encounters included SSI-related terms and synonyms, antibiotic, and culture orders. This study compares the Workbench and EHR.
AHRQ-funded; HS020921.
Citation: Karavite DJ, Miller MW, Ramos MJ .
User testing an information foraging tool for ambulatory surgical site infection surveillance.
Appl Clin Inform 2018 Oct;9(4):791-802. doi: 10.1055/s-0038-1675179..
Keywords: Surgery, Ambulatory Care and Surgery, Children/Adolescents, Electronic Health Records (EHRs), Health Information Technology (HIT), Healthcare-Associated Infections (HAIs), Patient Safety
George M, Iramiot JS, Muhindo R
Bacterial aetiology and antibiotic susceptibility profile of post-operative sepsis among surgical patients in a tertiary hospital in rural Eastern Uganda.
This study aimed at determining the prevalence and antimicrobial resistance patterns of bacterial pathogens isolated from post-operative wound infections at Mbale Regional Referral Hospital. The investigators found that Staphylococcus aureus was the most common causative agent associated with postoperative sepsis with most of the strains being MRSA. Multi-drug resistance was observed in 60.6% of the isolated organisms in their study.
AHRQ-funded; HS020098.
Citation: George M, Iramiot JS, Muhindo R .
Bacterial aetiology and antibiotic susceptibility profile of post-operative sepsis among surgical patients in a tertiary hospital in rural Eastern Uganda.
Microbiol Res J Int 2018;24(2). doi: 10.9734/mrji/2018/41690..
Keywords: Adverse Events, Healthcare-Associated Infections (HAIs), Sepsis, Surgery
Yokoe DS, Avery TR, Platt R
Ranking hospitals based on colon surgery and abdominal hysterectomy surgical site infection outcomes: impact of limiting surveillance to the operative hospital.
This study examined how hospitals are ranked based on colon surgery and abdominal surgical site infection (SSI) outcomes. This ranking can impact how financial penalties are determined. Currently SSI surveillance focuses mainly on the operative hospital, but patients sometimes go to a different hospital after an SSI as opposed to readmission in the operative hospital. The authors used data from a California statewide hospital registry to assess for evidence of SSI for surgeries performed from March 2011 through November 2013. This analysis showed show that operational hospital surveillance alone would have missed 7.2% of colon surgery and 13.4% of abdominal hysterectomy SSIs. This leads to an inaccurate assignment or avoidance of financial penalties for approximately 1 in 11-16 hospitals.
AHRQ-funded; HS021424.
Citation: Yokoe DS, Avery TR, Platt R .
Ranking hospitals based on colon surgery and abdominal hysterectomy surgical site infection outcomes: impact of limiting surveillance to the operative hospital.
Clin Infect Dis 2018 Sep 14;67(7):1096-102. doi: 10.1093/cid/ciy223..
Keywords: Surgery, Healthcare-Associated Infections (HAIs), Infectious Diseases, Injuries and Wounds, Adverse Events, Hospitals, Payment, Patient Safety, Provider Performance
Thompson MP, Cabrera L, Strobel RJ
Association between postoperative pneumonia and 90-day episode payments and outcomes among Medicare beneficiaries undergoing cardiac surgery.
Postoperative pneumonia is the most common healthcare-associated infection in cardiac surgical patients, yet their impact across a 90-day episode of care remains unknown. The objective of this study was to examine the relationship between pneumonia and 90-day episode payments and outcomes among Medicare beneficiaries undergoing cardiac surgery. The investigators concluded that postoperative pneumonia was associated with significantly higher 90-day episode payments and inferior outcomes at the patient and hospital level.
AHRQ-funded; HS022535.
Citation: Thompson MP, Cabrera L, Strobel RJ .
Association between postoperative pneumonia and 90-day episode payments and outcomes among Medicare beneficiaries undergoing cardiac surgery.
Circ Cardiovasc Qual Outcomes 2018 Sep;11(9):e004818. doi: 10.1161/circoutcomes.118.004818..
Keywords: Elderly, Surgery, Medicare, Cardiovascular Conditions, Heart Disease and Health, Pneumonia, Payment, Healthcare Costs, Outcomes, Healthcare-Associated Infections (HAIs), Health Insurance
Grundmeier RW, Xiao R, Ross RK
Grundmeier RW, Xiao R, Ross RK, Ramos MJ, Karavite DJ, Michel JJ, Gerber JS, et al. Identifying surgical site infections in electronic health data using predictive models,.
The objective of this study was to prospectively derive and validate a prediction rule for detecting cases warranting investigation for surgical site infections (SSI) after ambulatory surgery. The investigators concluded that electronic health record data can facilitate SSI surveillance with adequate sensitivity and positive predictive value.
AHRQ-funded; HS020921.
Citation: Grundmeier RW, Xiao R, Ross RK .
Grundmeier RW, Xiao R, Ross RK, Ramos MJ, Karavite DJ, Michel JJ, Gerber JS, et al. Identifying surgical site infections in electronic health data using predictive models,.
J Am Med Inform Assoc 2018 Sep;25(9):1160-66. doi: 10.1093/jamia/ocy075..
Keywords: Healthcare-Associated Infections (HAIs), Injuries and Wounds, Surgery, Electronic Health Records (EHRs), Health Information Technology (HIT), Risk, Patient Safety, Adverse Events, Ambulatory Care and Surgery
Baker AW, Haridy S, Salem J
Performance of statistical process control methods for regional surgical site infection surveillance: a 10-year multicentre pilot study.
The authors performed a pilot study within a large network of community hospitals to evaluate performance of statistical process control (SPC) methods for detecting surgical site infections (SSI) outbreaks. Their findings illustrated the potential usefulness and feasibility of real-time SPC surveillance of SSI to rapidly identify outbreaks and improve patient safety. Further study is needed to optimize SPC chart selection and calculation, statistical outbreak detection rules and the process for reacting to signals of potential outbreaks.
AHRQ-funded; HS023821.
Citation: Baker AW, Haridy S, Salem J .
Performance of statistical process control methods for regional surgical site infection surveillance: a 10-year multicentre pilot study.
BMJ Qual Saf 2018 Aug;27(8):600-10. doi: 10.1136/bmjqs-2017-006474..
Keywords: Healthcare-Associated Infections (HAIs), Patient Safety, Surgery, Hospitals, Public Health, Prevention, Adverse Events
Lin DM, Carson KA, Lubomski LH
Statewide collaborative to reduce surgical site infections results of the Hawaii Surgical Unit-based Safety Program.
Surgical Site Infections (SSI) after colorectal surgery are common, lead to patient harm, and are costly to the healthcare system. This study's purpose was to evaluate the effectiveness of the Agency for Healthcare Research and Quality (AHRQ) Safety Program for Surgery in Hawaii. Participation in the program was associated with a 61.7% decrease in colorectal SSI rate and an increase in patient safety culture.
AHRQ-funded.
Citation: Lin DM, Carson KA, Lubomski LH .
Statewide collaborative to reduce surgical site infections results of the Hawaii Surgical Unit-based Safety Program.
J Am Coll Surg 2018 Aug;227(2):189-97.e1. doi: 10.1016/j.jamcollsurg.2018.04.031..
Keywords: Comprehensive Unit-based Safety Program (CUSP), Healthcare-Associated Infections (HAIs), Surgery, Surveys on Patient Safety Culture, Injuries and Wounds
Wahl TS, Patel FC, Goss LE
The obese colorectal surgery patient: surgical site infection and outcomes.
The purpose of this study was to understand the association between BMI and 30-day postoperative outcomes, including surgical site infection, among patients undergoing colorectal surgery. The study found that patients with increasing BMI showed an incremental and independent risk for adverse 30-day postoperative outcomes, especially surgical site infections.
AHRQ-funded; HS013852
Citation: Wahl TS, Patel FC, Goss LE .
The obese colorectal surgery patient: surgical site infection and outcomes.
Dis Colon Rectum 2018 Aug;61(8):938-45. doi: 10.1097/dcr.0000000000001085..
Keywords: Adverse Events, Healthcare-Associated Infections (HAIs), Obesity, Patient-Centered Outcomes Research, Surgery
Hsu HE, Kawai AT, Wang R
The impact of the Medicaid healthcare-associated condition program on mediastinitis following coronary artery bypass graft.
This study aimed to evaluate the impact of a program that eliminated additional Medicare payment for mediastinitis following coronary artery bypass graft (CABG) to include Medicaid on mediastinitis rates reported by the National Healthcare Safety Network (NHSN). It found that the 2012 Medicaid program to eliminate additional payments for mediastinitis following CABG had no impact on reported mediastinitis rates.
AHRQ-funded; HS025008; HS018414; HS000063.
Citation: Hsu HE, Kawai AT, Wang R .
The impact of the Medicaid healthcare-associated condition program on mediastinitis following coronary artery bypass graft.
Infect Control Hosp Epidemiol 2018 Jun;39(6):694-700. doi: 10.1017/ice.2018.69.
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Keywords: Cardiovascular Conditions, Payment, Healthcare-Associated Infections (HAIs), Patient Safety, Surgery
Allegranzi B, Aiken AM, Zeynep Kubilay N
A multimodal infection control and patient safety intervention to reduce surgical site infections in Africa: a multicentre, before-after, cohort study.
The researchers aimed to establish the effect of a multimodal intervention on surgical site infections (SSIs) in Africa. SSI cumulative incidence significantly decreased post intervention, from 8.0 percent to 3.8 percent and this decrease persisted in the sustainability period. A substantial improvement in compliance with prevention measures was consistently observed in the follow-up and sustainability periods.
AHRQ-funded; 290201000027.
Citation: Allegranzi B, Aiken AM, Zeynep Kubilay N .
A multimodal infection control and patient safety intervention to reduce surgical site infections in Africa: a multicentre, before-after, cohort study.
Lancet Infect Dis 2018 May;18(5):507-15. doi: 10.1016/s1473-3099(18)30107-5.
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Keywords: Healthcare-Associated Infections (HAIs), Patient Safety, Surgery, Injuries and Wounds, Prevention
Johnson SP, Zhong L, Chung KC
Perioperative antibiotics for clean hand surgery: a national study.
This research is a national study on the use of prophylactic antibiotics in soft tissue hand surgery when antimicrobials are not indicated. Insurance claims from the Truven MarketScan Databases were used to identify patients who had 1 of 5 outpatient surgery procedures including: open or endoscopic carpal tunnel release; trigger finger release; de Ouervain release, and wrist ganglion excision between 2009 and 2015. An increase of 72.5% in prophylactic intravenous antibiotics was shown from 2009 to 2015. Patients with a younger age, male sex, lower income, or obesity had higher odds of receiving antibiotics. Total charge for these antibiotics equaled $1.6 million.
AHRQ-funded; HS023313.
Citation: Johnson SP, Zhong L, Chung KC .
Perioperative antibiotics for clean hand surgery: a national study.
J Hand Surg Am 2018 May;43(5):407-16.e1. doi: 10.1016/j.jhsa.2017.11.018..
Keywords: Antibiotics, Antimicrobial Stewardship, Healthcare-Associated Infections (HAIs), Infectious Diseases, Medication, Patient Safety, Surgery
Taaffe K, Lee B, Ferrand Y
The influence of traffic, area location, and other factors on operating room microbial load.
The researchers sought to determine how the movement of patients, equipment, materials, staff, and door openings within the operating room (OR) affect microbial loads at various locations within the OR. They found that the microbial load was affected by the time of year that the samples were taken. Both microbial load measured by the air samplers and by settle plates in 1 area of the OR was correlated with the physical movement of people in the same area.
AHRQ-funded; HS024380.
Citation: Taaffe K, Lee B, Ferrand Y .
The influence of traffic, area location, and other factors on operating room microbial load.
Infect Control Hosp Epidemiol 2018 Apr;39(4):391-97. doi: 10.1017/ice.2017.323.
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Keywords: Surgery, Healthcare-Associated Infections (HAIs), Injuries and Wounds, Prevention, Patient Safety
Gunter RL, Fernandes-Taylor S, Rahman S
Feasibility of an image-based mobile health protocol for postoperative wound monitoring.
Many surgical site infections (SSIs) develop in the postdischarge period and are inadequately recognized by patients. To address this, the authors developed a mobile health protocol of remote wound monitoring using smartphone technology. The current study aims to establish its feasibility among patients and providers. It found that participant and provider satisfaction was universally high.
AHRQ-funded; HS023395.
Citation: Gunter RL, Fernandes-Taylor S, Rahman S .
Feasibility of an image-based mobile health protocol for postoperative wound monitoring.
J Am Coll Surg 2018 Mar;226(3):277-86. doi: 10.1016/j.jamcollsurg.2017.12.013.
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Keywords: Healthcare-Associated Infections (HAIs), Surgery, Injuries and Wounds, Telehealth, Patient Safety, Health Information Technology (HIT)