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Search All Research Studies
Topics
- Anxiety (1)
- Behavioral Health (5)
- Care Management (1)
- (-) Children/Adolescents (7)
- (-) Depression (7)
- Evidence-Based Practice (3)
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 7 of 7 Research Studies DisplayedIvlev I, Beil TL, Haynes JS
Rapid evidence review of digital cognitive-behavioral therapy for adolescents with depression.
This rapid evidence review was conducted to explore the benefits and harms of digital cognitive-behavioral therapy (dCBT) and the barriers to and facilitators of implementing dCBT for adolescents. An extensive literature review was done through December 6, 2021 for controlled trials conducted in settings highly applicable to the US. Additionally, the authors searched relevant systematic reviews for eligible studies. They identified 12 trials that examined the effects of nine dCBT programs. Overall, dCBT was slightly superior to other therapies in improving depression symptoms immediately, but not at a longer follow-up. There did not appear to be an increased risk for suicidal attempts or ideation with dCBT, however the number of events was very small. Potential barriers to implementing and maintaining dCBT included challenges engaging/retaining patients, developing infrastructure, and training therapists to facilitate dCBT. No data on harms or unintended negative consequences were reported in the included studies.
AHRQ-funded; HS026370.
Citation: Ivlev I, Beil TL, Haynes JS .
Rapid evidence review of digital cognitive-behavioral therapy for adolescents with depression.
J Adolesc Health 2022 Jul;71(1):14-19. doi: 10.1016/j.jadohealth.2022.01.220..
Keywords: Children/Adolescents, Depression, Behavioral Health, Evidence-Based Practice, Patient-Centered Outcomes Research
Liu FF, Adrian MC
Is treatment working? Detecting real change in the treatment of child and adolescent depression.
Effectiveness of evidence-based treatments for youth remain modest at best; while practice parameters recommend measurement-based care to enhance youth depression treatment, the literature offers few guidelines on how to use assessment results to inform care decisions or to detect real and clinically meaningful change. The purpose of this study was to produce reliable change indices for two commonly used standardized assessments of youth depression: Patient Health Questionnaire-9 items, Modified for Adolescents (PHQ-9A) and the Short Moods and Feelings Questionnaire (SMFQ).
AHRQ-funded; HS022982.
Citation: Liu FF, Adrian MC .
Is treatment working? Detecting real change in the treatment of child and adolescent depression.
J Am Acad Child Adolesc Psychiatry 2019 Dec;58(12):1157-64. doi: 10.1016/j.jaac.2019.02.011..
Keywords: Children/Adolescents, Depression, Behavioral Health, Evidence-Based Practice, Patient-Centered Outcomes Research
Lifland B, Wright DR, Mangione-Smith R
The impact of an adolescent depressive disorders clinical pathway on healthcare utilization.
The purpose of this study was to examine the association between level of adherence to an adolescent depressive disorders inpatient clinical pathway with psychiatric patients’ length of stay (LOS), cost, and readmissions. Patients in the high-adherence category were found to have significantly longer LOS and higher costs when compared to those in the low-adherence category. The authors conclude that understanding which of the care processes within the pathway are most cost-effective for improving patient-centered outcomes requires further investigation.
AHRQ-funded; HS024299.
Citation: Lifland B, Wright DR, Mangione-Smith R .
The impact of an adolescent depressive disorders clinical pathway on healthcare utilization.
Adm Policy Ment Health 2018 Nov;45(6):979-87. doi: 10.1007/s10488-018-0878-6..
Keywords: Care Management, Children/Adolescents, Depression, Healthcare Costs, Healthcare Utilization, Hospital Readmissions, Hospitalization, Inpatient Care, Behavioral Health, Outcomes, Patient-Centered Outcomes Research
Brunwasser SM, Gillham JE
Identifying moderators of response to the Penn Resiliency Program: a synthesis study.
Researchers sought to identify moderators of a cognitive-behavioral depression prevention program's effect on depressive symptoms among youth in early adolescence. Data from three randomized controlled trials of the Penn Resiliency Program (PRP) were aggregated to maximize statistical power and sample diversity. The primary analyses suggested that PRP's effects are limited to youth whose parents are unmarried.
AHRQ-funded; HS022990.
Citation: Brunwasser SM, Gillham JE .
Identifying moderators of response to the Penn Resiliency Program: a synthesis study.
Prev Sci 2018 Feb;19(Suppl 1):38-48. doi: 10.1007/s11121-015-0627-y.
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Keywords: Behavioral Health, Children/Adolescents, Depression, Patient-Centered Outcomes Research, Prevention
Brunwasser SM, Garber J
Programs for the prevention of youth depression: evaluation of efficacy, effectiveness, and readiness for dissemination.
This study used the Society for Prevention Research's Standards of Evidence to evaluate the degree to which existing depression prevention programs have established intervention efficacy, effectiveness, and readiness for dissemination. The authors concluded that although several programs have demonstrated promise in terms of efficacy, no depression prevention program for children or adolescents has garnered sufficient evidence of effectiveness under real-world conditions to warrant widespread dissemination.
AHRQ-funded; HS022990.
Citation: Brunwasser SM, Garber J .
Programs for the prevention of youth depression: evaluation of efficacy, effectiveness, and readiness for dissemination.
J Clin Child Adolesc Psychol 2016 Nov-Dec;45(6):763-83. doi: 10.1080/15374416.2015.1020541.
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Keywords: Children/Adolescents, Depression, Evidence-Based Practice, Patient-Centered Outcomes Research
Garber J, Brunwasser SM, Zerr AA
Treatment and prevention of depression and anxiety in youth: test of cross-over effects.
The present meta-analytic review examined whether interventions for children and adolescents that explicitly targeted either anxiety or depression showed treatment specificity or also impacted the other outcome (i.e. cross-over effects). Anxiety prevention studies (n = 14) significantly affected anxious, but not depressive symptoms, indicating no cross-over effect of anxiety prevention trials on depression. For depression prevention studies (n = 15), the effects were not significant for either depressive or anxiety symptoms, although the effect was significantly larger for depressive than for anxious symptoms.
AHRQ-funded; HS022990.
Citation: Garber J, Brunwasser SM, Zerr AA .
Treatment and prevention of depression and anxiety in youth: test of cross-over effects.
Depress Anxiety 2016 Oct;33(10):939-59. doi: 10.1002/da.22519.
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Keywords: Anxiety, Children/Adolescents, Depression, Patient-Centered Outcomes Research
Brent DA, Brunwasser SM, Hollon SD
Effect of a cognitive-behavioral prevention program on depression 6 years after implementation among at-risk adolescents: a randomized clinical trial.
The objective of this paper is to determine whether a cognitive-behavioral prevention (CBP) program reduced the incidence of depressive episodes, increased depression-free days, and improved developmental competence 6 years after implementation. Over the 75-month follow-up, youths assigned to CBP had a lower incidence of depression; the CBP program's overall significant effect was driven by a lower incidence of depressive episodes during the first 9 months after enrollment.
AHRQ-funded; HS022990.
Citation: Brent DA, Brunwasser SM, Hollon SD .
Effect of a cognitive-behavioral prevention program on depression 6 years after implementation among at-risk adolescents: a randomized clinical trial.
JAMA Psychiatry 2015 Nov;72(11):1110-8. doi: 10.1001/jamapsychiatry.2015.1559.
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Keywords: Behavioral Health, Children/Adolescents, Depression, Patient-Centered Outcomes Research