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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 1 of 1 Research Studies DisplayedMazi PB, Olsen MA, Stwalley D
Attributable mortality of Candida bloodstream infections in the modern era: a propensity score analysis.
The purpose of this retrospective cohort study was to quantify the mortality attributed to Candida bloodstream infections (BSI). The researchers identified 626 adult patients with Candida BSI that were frequency-matched with 6269 control patients with similar candida BSI risk-factors. The study found that the 90-day crude mortality rate was 42.4% for Candida BSI cases and 17.1% for frequency matched controls. After propensity score-matching, the attributable risk difference for 90-day mortality was 28.4% with hazard ratio (HR) of 2.12. In the stratified analysis, the 90-day mortality risk was highest in patients in the lowest risk quintile to develop Candida BSI. Patients in this lowest risk quintile accounted for 61% of the untreated patients with Candida BSI. Sixty-nine percent of untreated patients died versus 35% of treated patients.
AHRQ-funded; HS019455.
Citation: Mazi PB, Olsen MA, Stwalley D .
Attributable mortality of Candida bloodstream infections in the modern era: a propensity score analysis.
Clin Infect Dis 2022 Sep 29;75(6):1031-36. doi: 10.1093/cid/ciac004..
Keywords: Infectious Diseases, Mortality, Sepsis