National Healthcare Quality and Disparities Report
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Topics
- Comparative Effectiveness (1)
- (-) Evidence-Based Practice (2)
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- (-) Newborns/Infants (2)
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 2 of 2 Research Studies DisplayedGuirguis-Blake JM, Evans CV, Rushkin M
Ocular prophylaxis for gonococcal ophthalmia neonatorum: updated evidence report and systematic review for the US Preventive Services Task Force.
This evidence report and systematic review was commissioned for the U.S. Preventive Services Task Force to update the evidence of using prophylactic ocular topic medication for all newborns to prevent gonococcal ophthalmia neonatorum (GON) which can cause blindness if not treated immediately. Many articles were screened for inclusion, and of those included the recommendations remained an “A” grade recommendation, which is to apply the topical medication on all newborns due to an increase in syphilis prevalence.
AHRQ-funded; 290201500007I.
Citation: Guirguis-Blake JM, Evans CV, Rushkin M .
Ocular prophylaxis for gonococcal ophthalmia neonatorum: updated evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2019 Jan 29;321(4):404-06. doi: 10.1001/jama.2018.17847..
Keywords: Evidence-Based Practice, Eye Disease and Health, Guidelines, Newborns/Infants, Prevention, U.S. Preventive Services Task Force (USPSTF)
Wu P, Escobar GJ, Gebretsadik T
Effectiveness of respiratory syncytial virus immunoprophylaxis in reducing bronchiolitis hospitalizations among high-risk infants.
This retrospective cohort study examined the effectiveness of respiratory syncytial virus (RSV) prophylaxis for infants born between 1996 and 2008. The infants were enrolled in the Kaiser Permanente Northern California integrated health system. Infants who ever received RSV immunoprophylaxis had a 32% decreased risk of bronchiolitis hospitalization and finants with chronic lung disease (CLD) had a 52% decreased risk. The 2014 American Academy of Pediatrics (AAP) guidelines changed recommendations for RSV immunoprophylaxis which made 48% of infants no longer eligible but nearly all infants with CLD would remain eligible.
AHRQ-funded; HS018454.
Citation: Wu P, Escobar GJ, Gebretsadik T .
Effectiveness of respiratory syncytial virus immunoprophylaxis in reducing bronchiolitis hospitalizations among high-risk infants.
Am J Epidemiol 2018 Jul;187(7):1490-500. doi: 10.1093/aje/kwy008..
Keywords: Comparative Effectiveness, Evidence-Based Practice, Hospitalization, Newborns/Infants, Outcomes, Patient-Centered Outcomes Research, Prevention, Respiratory Conditions, Risk