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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 4 of 4 Research Studies DisplayedFlory JH, Keating SJ, Siscovick D
Identifying prevalence and risk factors for metformin non-persistence: a retrospective cohort study using an electronic health record.
Non-persistence may be a significant barrier to the use of metformin. The objective of this study was to assess reasons for metformin non-persistence, and whether initial metformin dosing or use of extended release (ER) formulations affect persistence to metformin therapy. The investigators concluded that their data supported the routine prescribing of low starting doses of metformin as a tool to improve persistence.
AHRQ-funded; HS023898.
Citation: Flory JH, Keating SJ, Siscovick D .
Identifying prevalence and risk factors for metformin non-persistence: a retrospective cohort study using an electronic health record.
BMJ Open 2018 Jul 23;8(7):e021505. doi: 10.1136/bmjopen-2018-021505..
Keywords: Diabetes, Electronic Health Records (EHRs), Health Information Technology (HIT), Medication, Patient Adherence/Compliance, Outcomes, Patient-Centered Outcomes Research, Risk
Rasmussen E, Fosnacht Morgan AM, Munson R
Use of an electronic medical record to track adherence to the mediterranean diet in a US neurology clinical practice.
The authors of this paper describe their experience with routinely capturing and analyzing Mediterranean diet data via structured clinical documentation support tools built into the electronic medical record and describe adherence to the Mediterranean diet in patients at risk for either stroke or dementia in a US neurology clinical practice.
AHRQ-funded; HS024057.
Citation: Rasmussen E, Fosnacht Morgan AM, Munson R .
Use of an electronic medical record to track adherence to the mediterranean diet in a US neurology clinical practice.
Mayo Clin Proc Innov Qual Outcomes 2018 Mar;2(1):49-59. doi: 10.1016/j.mayocpiqo.2017.12.003..
Keywords: Electronic Health Records (EHRs), Nutrition, Patient Adherence/Compliance
Flory J, Gerhard T, Stempniewicz N
Comparative adherence to diabetes drugs: an analysis of electronic health records and claims data.
The objective of this brief report is to compare adherence rates for 6 major classes of diabetes medications: metformin, sulfonylurea, thiazolidinedione, basal insulin, DPP-4 inhibitors, and GLP-1 receptor agonists. The authors note that the rates at which diabetes drugs are prescribed, and the rates at which patients actually take them, differ substantially. The authors also note that the physicians should be aware of potentially significant challenges concerning adherence to newer agents.
AHRQ-funded; HS023898.
Citation: Flory J, Gerhard T, Stempniewicz N .
Comparative adherence to diabetes drugs: an analysis of electronic health records and claims data.
Diabetes Obes Metab 2017 Aug;19(8):1184-87. doi: 10.1111/dom.12931..
Keywords: Diabetes, Electronic Health Records (EHRs), Patient Adherence/Compliance, Practice Patterns, Medication
Lyles CR, Sarkar U, Schillinger D
Refilling medications through an online patient portal: consistent improvements in adherence across racial/ethnic groups.
The researchers evaluated longitudinal changes in statin adherence to determine whether racial/ethnic minorities initiating use of the online refill function in patient portals had similar changes over time compared with whites. Their examination of a retrospective cohort of diabetes patients who were existing patient portal users found that all racial/ethnic minority groups had poorer baseline statin adherence compared with whites.
AHRQ-funded; HS022408.
Citation: Lyles CR, Sarkar U, Schillinger D .
Refilling medications through an online patient portal: consistent improvements in adherence across racial/ethnic groups.
J Am Med Inform Assoc 2016 Apr;23(e1):e28-e33. doi: 10.1093/jamia/ocv126.
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Keywords: Medication, Web-Based, Patient Adherence/Compliance, Electronic Health Records (EHRs), Racial and Ethnic Minorities