National Healthcare Quality and Disparities Report
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AHRQ Research Studies Date
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
101 to 121 of 121 Research Studies DisplayedHsu DY, Brieva J, Silverberg NB
Pediatric Stevens-Johnson syndrome and toxic epidermal necrolysis in the United States.
In this study, the investigators sought to determine the morbidity, mortality, and comorbid health conditions of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in US children. They found that the incidences of SJS, SJS-TEN, and TEN were a mean 5.3, 0.8, and 0.4 cases per million children per year in the US, respectively.The investigators concluded that pediatric SJS/TEN poses a substantial health burden in the United States.
AHRQ-funded; HS023011.
Citation: Hsu DY, Brieva J, Silverberg NB .
Pediatric Stevens-Johnson syndrome and toxic epidermal necrolysis in the United States.
J Am Acad Dermatol 2017 May;76(5):811-17.e4. doi: 10.1016/j.jaad.2016.12.024..
Keywords: Children/Adolescents, Healthcare Cost and Utilization Project (HCUP), Skin Conditions
Kwa MC, Ardalan K, Laumann AE
Validation of International Classification of Diseases codes for the epidemiologic study of dermatomyositis.
The authors assessed the validity of using ICD-9-CM code 710.3 to identify adult patients with dermatomyositis in outpatient and inpatient settings. They found that one or more occurrences of ICD-9 code 710.3 is insufficient to support the diagnosis of dermatomyositis in the outpatient setting, but that ICD-9 710.3 codes appear to be valid in the inpatient setting.
AHRQ-funded; HS023011.
Citation: Kwa MC, Ardalan K, Laumann AE .
Validation of International Classification of Diseases codes for the epidemiologic study of dermatomyositis.
Arthritis Care Res 2017 May;69(5):753-57. doi: 10.1002/acr.23010.
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Keywords: Diagnostic Safety and Quality, Patient-Centered Outcomes Research, Skin Conditions
Sisic M, Kirby JS, Boyal S
Development of a quality-of-life measure for hidradenitis suppurativa.
The objective of this study was to develop a QoL instrument for hidradenitis suppurativa (HS-QoL) in accordance with recommended standards. : Concept elicitation interviews with patients with HS generated 12 themes. Most frequently reported were impacts on daily activities and symptoms due to HS. These themes, along with literature review and input from clinical experts, informed development of the HS-QoL-v1.
AHRQ-funded; HS024585.
Citation: Sisic M, Kirby JS, Boyal S .
Development of a quality-of-life measure for hidradenitis suppurativa.
J Cutan Med Surg 2017 Mar/Apr;21(2):152-55. doi: 10.1177/1203475416677721.
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Keywords: Patient Experience, Quality Measures, Quality of Life, Skin Conditions
Togias A, Cooper SF, Acebal ML
Addendum guidelines for the prevention of peanut allergy in the United States: report of the National Institute of Allergy and Infectious Diseases-sponsored expert panel.
Along with 25 professional organizations, federal agencies, and patient advocacy groups, the National Institute of Allergy and Infectious Diseases facilitated development of addendum guidelines to specifically address the prevention of peanut allergy. This addendum provides 3 separate guidelines for infants at various risk levels for the development of peanut allergy and is intended for use by a wide variety of health care providers.
AHRQ-funded; HS024599.
Citation: Togias A, Cooper SF, Acebal ML .
Addendum guidelines for the prevention of peanut allergy in the United States: report of the National Institute of Allergy and Infectious Diseases-sponsored expert panel.
J Allergy Clin Immunol 2017 Jan;139(1):29-44. doi: 10.1016/j.jaci.2016.10.010.
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Keywords: Guidelines, Prevention, Skin Conditions
Kantor R, Kim A, Thyssen JP
Association of atopic dermatitis with smoking: a systematic review and meta-analysis.
The authors examined the association between atopic dermatitis (AD) and exposure to tobacco smoke. They found that a diagnosis of AD was associated with higher odds of active smoking and exposure to passive smoke but not to maternal smoking during pregnancy, and concluded that active and passive tobacco smoke exposure are associated with increased AD prevalence.
AHRQ-funded; HS023011.
Citation: Kantor R, Kim A, Thyssen JP .
Association of atopic dermatitis with smoking: a systematic review and meta-analysis.
J Am Acad Dermatol 2016 Dec;75(6):1119-25.e1. doi: 10.1016/j.jaad.2016.07.017.
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Keywords: Skin Conditions, Tobacco Use, Risk, Evidence-Based Practice
Strom MA, Fishbein AB, Paller AS
Association between atopic dermatitis and attention deficit hyperactivity disorder in US children and adults.
The researchers sought to determine if childhood and adult atopic dermatitis (AD) and AD severity are associated with ADD/ADHD and to delineate the factors contributing to such an association. It found that AD was most strongly associated with severe ADHD. AD unaccompanied by other allergic disease, was also associated with increased risk of ADD/ADHD in children.
AHRQ-funded; HS023011.
Citation: Strom MA, Fishbein AB, Paller AS .
Association between atopic dermatitis and attention deficit hyperactivity disorder in US children and adults.
Br J Dermatol 2016 Nov;175(5):920-29. doi: 10.1111/bjd.14697.
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Keywords: Skin Conditions, Behavioral Health, Risk
Kantor R, Thyssen JP, Paller AS
Atopic dermatitis, atopic eczema, or eczema? A systematic review, meta-analysis, and recommendation for uniform use of 'atopic dermatitis'.
The authors sought to determine the most commonly-used terms for atopic dermatitis. They found that atopic dermatitis was the most commonly-used term in studies across almost all publication types, languages, and journals and appears to be increasing in popularity. They concluded by suggesting the use of the term atopic dermatitis in publications, healthcare clinician training, and patient education.
AHRQ-funded; HS023011.
Citation: Kantor R, Thyssen JP, Paller AS .
Atopic dermatitis, atopic eczema, or eczema? A systematic review, meta-analysis, and recommendation for uniform use of 'atopic dermatitis'.
Allergy 2016 Oct;71(10):1480-5. doi: 10.1111/all.12982.
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Keywords: Education: Patient and Caregiver, Diagnostic Safety and Quality, Patient-Centered Healthcare, Clinician-Patient Communication, Skin Conditions
Kirby JS, Sisic M, Tan J
Exploring coping strategies for patients with hidradenitis suppurativa.
The authors explored the coping strategies of individuals with hidradenitis suppurativa (HS). They found that negative coping included behavioral disengagement and social isolation, while positive coping included use of humor and positive reframing as well as the support of others.
AHRQ-funded; HS024585.
Citation: Kirby JS, Sisic M, Tan J .
Exploring coping strategies for patients with hidradenitis suppurativa.
JAMA Dermatol 2016 Oct;152(10):1166-67. doi: 10.1001/jamadermatol.2016.1942.
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Keywords: Health Status, Quality of Life, Patient Self-Management, Skin Conditions
Kathuria P, Silverberg JI
Association of pollution and climate with atopic eczema in US children.
The authors sought to determine the relationship between childhood eczema, environmental pollutants, and climate. They found that pollutants, in conjunction with climate factors, may differentially impact eczema prevalence and severity.
AHRQ-funded; HS023011.
Citation: Kathuria P, Silverberg JI .
Association of pollution and climate with atopic eczema in US children.
Pediatr Allergy Immunol 2016 Aug;27(5):478-85. doi: 10.1111/pai.12543.
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Keywords: Children/Adolescents, Children/Adolescents, Skin Conditions
Silverberg JI, Song J, Pinto D
Atopic dermatitis is associated with less physical activity in US adults.
The authors sought to use objective measures to confirm whether adults with atopic dermatitis (AD) have decreased vigorous physical activity. Their results confirmed and expanded on previous studies that found less self-reported vigorous physical activity among adults with AD.
AHRQ-funded; HS023011.
Citation: Silverberg JI, Song J, Pinto D .
Atopic dermatitis is associated with less physical activity in US adults.
J Invest Dermatol 2016 Aug;136(8):1714-6. doi: 10.1016/j.jid.2016.04.025.
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Keywords: Lifestyle Changes, Risk, Skin Conditions
Park JK, Yang JA, Ahn EY
Survival rates of cancer patients with and without rheumatic disease: a retrospective cohort analysis.
The researchers compared the outcomes of gastric, colon, lung, and breast cancer patients with and without rheumatic diseases. They found that rheumatoid arthritis and dermatomyositis/polymyositis seemed to be associated with a higher mortality in patients with lung or breast cancers, whereas systemic sclerosis seemed to be associated with decreased mortality in patients with lung cancer.
AHRQ-funded; HS018517.
Citation: Park JK, Yang JA, Ahn EY .
Survival rates of cancer patients with and without rheumatic disease: a retrospective cohort analysis.
BMC Cancer 2016 Jul 4;16:381. doi: 10.1186/s12885-016-2444-5.
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Keywords: Cancer, Mortality, Arthritis, Skin Conditions
Strom MA, Silverberg JI
Associations of physical activity and sedentary behavior with atopic disease in United States children.
The purpose of this study was to determine if eczema, asthma, and hay fever are associated with vigorous physical activity, television/video game usage, and sports participation and if sleep disturbance modifies such associations. The investigators concluded that children with severe atopic disease, accompanied by sleep disturbance, have higher risk of sedentary behaviors.
AHRQ-funded; HS023011.
Citation: Strom MA, Silverberg JI .
Associations of physical activity and sedentary behavior with atopic disease in United States children.
J Pediatr 2016 Jul;174:247-53.e3. doi: 10.1016/j.jpeds.2016.03.063..
Keywords: Children/Adolescents, Lifestyle Changes, Risk, Skin Conditions
Volkmann ER, Chang YL, Barroso N
Association of systemic sclerosis with a unique colonic microbial consortium.
The authors compared colonic microbial composition in systemic sclerosis (SSc) patients and healthy controls and determined whether certain microbial genera are associated with gastrointestinal (GI) tract symptoms in patients with SSc. They found that SSc patients had decreased levels of commensal bacteria and increased levels of pathobiont bacteria compared with healthy controls. They concluded that this unique ecologic change may perpetuate immunologic aberrations and contribute to clinical manifestations of SSc.
AHRQ-funded; HS021747.
Citation: Volkmann ER, Chang YL, Barroso N .
Association of systemic sclerosis with a unique colonic microbial consortium.
Arthritis Rheumatol 2016 Jun;68(6):1483-92. doi: 10.1002/art.39572.
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Keywords: Adverse Events, Digestive Disease and Health, Skin Conditions
Silverberg JI
Association between childhood eczema and headaches: an analysis of 19 US population-based studies.
The researchers sought to determine whether childhood eczema is associated with increased headaches and whether such association is related to fatigue or sleep disturbance. After analyzing national survey data from 401,002 children and adolescents, they found that eczema is associated with increased headaches in childhood, particularly in patients with severe disease accompanied by atopy, fatigue, and sleep disturbances.
AHRQ-funded; HS023011.
Citation: Silverberg JI .
Association between childhood eczema and headaches: an analysis of 19 US population-based studies.
J Allergy Clin Immunol 2016 Feb;137(2):492-99.e5. doi: 10.1016/j.jaci.2015.07.020.
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Keywords: Children/Adolescents, Neurological Disorders, Sleep Problems, Risk, Skin Conditions
Banerjee M, Lao CD, Wancata LM
Implications of age and conditional survival estimates for patients with melanoma.
This study identified newly diagnosed cutaneous melanoma patients and estimated conditional 5-year survival. Over time, conditional survival estimates improved for older patients with localized and regional disease. Understanding the conditional 5-year disease-specific survival of melanoma based on age and stage can help patients and physicians, informing decision-making about treatment and surveillance.
AHRQ-funded; HS020937.
Citation: Banerjee M, Lao CD, Wancata LM .
Implications of age and conditional survival estimates for patients with melanoma.
Melanoma Res 2016 Feb;26(1):77-82. doi: 10.1097/cmr.0000000000000213.
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Keywords: Elderly, Cancer: Skin Cancer, Cancer, Mortality, Skin Conditions
Strom MA, Silverberg JI
Eczema is associated with childhood speech disorder: a retrospective analysis from the National Survey of Children's Health and the National Health Interview Survey.
The researchers sought to determine if eczema is associated with an increased risk of a speech disorder. They found that pooled prevalence of speech disorder in children with eczema was 4.7 percent compared with 2.2 percent in children without eczema. They concluded that pediatric eczema may be associated with increased risk of speech disorder.
AHRQ-funded; HS023011.
Citation: Strom MA, Silverberg JI .
Eczema is associated with childhood speech disorder: a retrospective analysis from the National Survey of Children's Health and the National Health Interview Survey.
J Pediatr 2016 Jan;168:185-92.e4. doi: 10.1016/j.jpeds.2015.09.066.
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Keywords: Children/Adolescents, Skin Conditions
Silverberg JI, Patel N, Immaneni S
Assessment of atopic dermatitis using self-report and caregiver report: a multicentre validation study.
The researchers sought to validate the assessment of self- and caregiver-reported eczema. They performed a prospective multicentre dermatology-practice-based study (three sites) to determine the validity of caregiver- and self-reported ever having eczema and 1-year history of eczema. Their conclusion was that self- and caregiver-reported diagnosis of eczema ever or in the past year based on a single question demonstrated sufficient validity for the epidemiological study of eczema.
AHRQ-funded; HS023011.
Citation: Silverberg JI, Patel N, Immaneni S .
Assessment of atopic dermatitis using self-report and caregiver report: a multicentre validation study.
Br J Dermatol 2015 Dec;173(6):1400-4. doi: 10.1111/bjd.14031.
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Keywords: Skin Conditions, Diagnostic Safety and Quality, Caregiving
Yu SH, Silverberg JI
Association between atopic dermatitis and depression in US adults.
The researchers sought to determine the prevalence of depression in US adults with atopic dermatitis (AD). They concluded that approximately one in three US adults with AD reported any symptoms of depression and one in three adults with AD met diagnostic criteria for major depressive disorder.
AHRQ-funded; HS023011.
Citation: Yu SH, Silverberg JI .
Association between atopic dermatitis and depression in US adults.
J Invest Dermatol 2015 Dec;135(12):3183-6. doi: 10.1038/jid.2015.337..
Keywords: Depression, Behavioral Health, Risk, Skin Conditions
Li JC, Silverberg JI
Varicella infection is not associated with increasing prevalence of eczema: a U.S. population-based study.
The investigators sought to understand the impact of declining rates of chickenpox infection on the prevalence of eczema. Using National Health Interview Survey data, they found that eczema was inversely associated with chickenpox. They concluded that lower rates of chickenpox infection secondary to widespread vaccination against varicella zoster virus are not contributing to higher rates of childhood eczema in the U.S.
AHRQ-funded; HS023011.
Citation: Li JC, Silverberg JI .
Varicella infection is not associated with increasing prevalence of eczema: a U.S. population-based study.
Br J Dermatol 2015 Nov;173(5):1169-74. doi: 10.1111/bjd.14028.
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Keywords: Infectious Diseases, Skin Conditions, Skin Conditions, Vaccination
Silverberg JI
Health care utilization, patient costs, and access to care in US adults with eczema: a population-based study.
This study examined the out-of-pocket costs, health care access and utilization in adult eczema in the United States. It found that adults with eczema had $371 to $489 higher out-of-pocket costs per person-year compared with those without eczema, with higher odds of increased out-of-pocket costs.
AHRQ-funded; HS023011.
Citation: Silverberg JI .
Health care utilization, patient costs, and access to care in US adults with eczema: a population-based study.
JAMA Dermatol 2015 Jul;151(7):743-52. doi: 10.1001/jamadermatol.2014.5432.
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Keywords: Access to Care, Healthcare Costs, Healthcare Utilization, Skin Conditions
Balachandra S, Pardos de la Gandara M, Salvato S
Recurrent furunculosis caused by a community-acquired Staphylococcus aureus strain belonging to the USA300 clone.
This study is a clinical history of a patient with recurrent skin infections caused by a strain of CA-MRSA belonging to the USA300 clone. The strain was recovered repeatedly from wounds and lower body sites but never from the nostrils. The clinical history of recurrence strongly suggests the existence of a common environmental source of the MRSA strain.
AHRQ-funded; HS021667.
Citation: Balachandra S, Pardos de la Gandara M, Salvato S .
Recurrent furunculosis caused by a community-acquired Staphylococcus aureus strain belonging to the USA300 clone.
Microb Drug Resist 2015 Apr;21(2):237-43. doi: 10.1089/mdr.2014.0283..
Keywords: Skin Conditions, Methicillin-Resistant Staphylococcus aureus (MRSA), Injuries and Wounds, Community-Acquired Infections