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- Asthma (1)
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- (-) Quality of Life (26)
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- Shared Decision Making (2)
- Sickle Cell Disease (2)
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 25 of 26 Research Studies DisplayedCrockett KB, Turan B
Moment-to-moment changes in perceived social support and pain for men living with HIV: an experience sampling study.
In this study, the investigators used an experience sampling method (also called Ecological Momentary Assessment) to assess moment-to-moment experiences of pain and social support 3 times a day for 7 days in a sample of 109 men living with HIV. They found that within-persons, experiences of daily social support reduced experiences of pain. Between-persons, attachment style may have influenced how individuals make use of social support in coping with experiences of pain.
AHRQ-funded; HS013852.
Citation: Crockett KB, Turan B .
Moment-to-moment changes in perceived social support and pain for men living with HIV: an experience sampling study.
Pain 2018 Dec;159(12):2503-11. doi: 10.1097/j.pain.0000000000001354..
Keywords: Human Immunodeficiency Virus (HIV), Pain, Quality of Life
Francis BA, Beaumont J, Mass MB
Depressive symptom prevalence after intracerebral hemorrhage: a multi-center study.
In this multi-center study, the investigators examined depressive symptom prevalence after intracerebral hemorrhage. The investigators concluded that depressive symptoms in patients with intracerebral hemorrhage (ICH) are more common than medication treatment or a coded diagnosis in a multi-center cohort, and are a potential opportunity for additional treatment to improve outcomes. There are currently no AHA/ASA treatment guidelines for depression screening of patients with ICH.
AHRQ-funded; HS023437; HS000078.
Citation: Francis BA, Beaumont J, Mass MB .
Depressive symptom prevalence after intracerebral hemorrhage: a multi-center study.
J Patient Rep Outcomes 2018 Nov 23;2(1):55. doi: 10.1186/s41687-018-0083-0..
Keywords: Depression, Patient-Centered Outcomes Research, Quality of Life
Annapureddy A, Valero-Elizondo J, Khera R
Association between financial burden, quality of life, and mental health among those with atherosclerotic cardiovascular disease in the United States.
Currently, there is little information about the relationship between the financial burden of healthcare for patients with atherosclerotic cardiovascular disease (ASCVD) and their health-related quality of life (HRQoL), well-being, and psychological health. Accordingly, the authors of this study, determined the relationship between healthcare financial burden and patient-reported HRQoL, self-perception of health, psychological distress, and risk of depression in a nationally representative US adult population with established ASCVD.
AHRQ-funded; HS023000.
Citation: Annapureddy A, Valero-Elizondo J, Khera R .
Association between financial burden, quality of life, and mental health among those with atherosclerotic cardiovascular disease in the United States.
Circ Cardiovasc Qual Outcomes 2018 Nov;11(11):e005180. doi: 10.1161/circoutcomes.118.005180..
Keywords: Cardiovascular Conditions, Healthcare Costs, Behavioral Health, Quality of Life
Roydhouse JK, Gutman R, Keating NL
The association of proxy care engagement with proxy reports of patient experience and quality of life.
The purpose of this study was to assess the association of proxy-specific covariates with proxy-reported patient cancer care experience, quality rating, and quality of life. The investigators concluded that collecting data on proxy engagement in care is warranted if proxy responses are used.
AHRQ-funded; HS000011.
Citation: Roydhouse JK, Gutman R, Keating NL .
The association of proxy care engagement with proxy reports of patient experience and quality of life.
Health Serv Res 2018 Oct;53(5):3809-24. doi: 10.1111/1475-6773.12980..
Keywords: Cancer, Patient Experience, Patient and Family Engagement, Quality of Life
Abutaleb A, Buchwald A, Chudy-Onwugaje K
Inflammatory bowel disease telemedicine clinical trial: impact of educational text messages on disease-specific knowledge over 1 year.
The authors aimed to determine if delivery of educational messages through a telemedicine system improves inflammatory bowel disease (IBD) knowledge. They found that, although telemedicine improves IBD-specific knowledge through text messaging, telemedicine is not superior to education given through standard visits at referral centers.
AHRQ-funded; HS018975.
Citation: Abutaleb A, Buchwald A, Chudy-Onwugaje K .
Inflammatory bowel disease telemedicine clinical trial: impact of educational text messages on disease-specific knowledge over 1 year.
Inflamm Bowel Dis 2018 Sep 15;24(10):2191-97. doi: 10.1093/ibd/izy149..
Keywords: Telehealth, Health Information Technology (HIT), Digestive Disease and Health, Education: Patient and Caregiver, Health Literacy, Quality of Life
Thorlacius L, Ingram JR, Villumsen B
A core domain set for hidradenitis suppurativa trial outcomes: an international Delphi process.
This article describes the outcome of six stakeholder groups participating in a Delphi process to create a core outcomes set (COS) for hidradenitis suppurative (HS) research. Five anonymous e-Delphi rounds and four face-to-face consensus meetings were conducted. A total of 41 patients and 52 healthcare professionals (HCPs) from 19 countries and 4 continents participated. The consensus adopted included five domains were approved: disease course, physical signs, HS-specific quality of life, pain, and global assessments.
AHRQ-funded; HS024585.
Citation: Thorlacius L, Ingram JR, Villumsen B .
A core domain set for hidradenitis suppurativa trial outcomes: an international Delphi process.
Br J Dermatol 2018 Sep;179(3):642-50. doi: 10.1111/bjd.16672..
Keywords: Skin Conditions, Health Services Research (HSR), Research Methodologies, Quality of Life
Meyers S, Claire Simon K, Bergman-Bock S
Structured clinical documentation to improve quality and support practice-based research in headache.
The authors developed a proprietary toolkit to aid clinicians when creating clinical documentation in electronic medical records (EMRs). This toolkit will help clinicians provide discrete data and not unstructured free text which many clinicians enter into the EMR. The toolkit collects hundreds of fields of data and interprets score tests for a number of difference assessment tools for anxiety disorder, depression, migraine disability, and insomnia. The toolkit was used at 4346 initial patient visits as of April 1, 2018. The toolkit is being shared with other clinics as part of the Neurology Practice-Based Research Network.
AHRQ-funded; HS024057.
Citation: Meyers S, Claire Simon K, Bergman-Bock S .
Structured clinical documentation to improve quality and support practice-based research in headache.
Headache 2018 Sep;58(8):1211-18. doi: 10.1111/head.13348..
Keywords: Quality Improvement, Quality of Life, Tools & Toolkits, Neurological Disorders, Electronic Health Records (EHRs), Health Information Technology (HIT), Practice-Based Research Network (PBRN)
Badawy SM, Thompson AA, Liem RI
Beliefs about hydroxyurea in youth with sickle cell disease.
The objectives of this study were to assess beliefs about hydroxyurea using the Beliefs about Medicines Questionnaire (BMQ), and to examine the relationship of patients' beliefs to their hydroxyurea adherence and health-related quality of life (HRQOL). The investigators found that beliefs about hydroxyurea correlated with HRQOL scores and adherence levels. The authors suggest that addressing patients' concerns about hydroxyurea and medications overall as well as routine assessment of adherence and beliefs could help to overcome adherence barriers.
AHRQ-funded; HS023011.
Citation: Badawy SM, Thompson AA, Liem RI .
Beliefs about hydroxyurea in youth with sickle cell disease.
Hematol Oncol Stem Cell Ther 2018 Sep;11(3):142-48. doi: 10.1016/j.hemonc.2018.01.001..
Keywords: Children/Adolescents, Medication, Patient Adherence/Compliance, Quality of Life, Sickle Cell Disease
Naidech AM, Beaumont J, Muldoon K
Prophylactic seizure medication and health-related quality of life after intracerebral hemorrhage.
Using a prospective cohort study design, the investigators tested the hypothesis that prophylactic levetiracetam is independently associated with differences in cognitive function health-related quality of life. They found that prophylactic levetiracetam was independently associated with lower cognitive function health-related quality of life at follow-up after intracerebral hemorrhage.
AHRQ-funded; HS023437.
Citation: Naidech AM, Beaumont J, Muldoon K .
Prophylactic seizure medication and health-related quality of life after intracerebral hemorrhage.
Crit Care Med 2018 Sep;46(9):1480-85. doi: 10.1097/ccm.0000000000003272..
Keywords: Medication, Neurological Disorders, Quality of Life
Koleck TA, Suero-Tejeda N, Bakken S
The influence of Latino symptom experience on participation in usual activities and satisfaction with participation in social roles.
This study investigated what is known as the Latino symptom experience and how it influences participation in daily activities and satisfaction with participation in social roles. A secondary analysis of survey data from the Health-Related Quality of Life 30-day survey and the Patient Reported Outcome Measurement System survey. Participants were mostly female and Dominican. The surveys were mostly conducted in Spanish in the community setting. There was a negative correlation between the number of days with poor physical or mental health and levels of satisfaction and participation in usual activities.
AHRQ-funded; HS022961.
Citation: Koleck TA, Suero-Tejeda N, Bakken S .
The influence of Latino symptom experience on participation in usual activities and satisfaction with participation in social roles.
Hisp Health Care Int 2018 Sep;16(3):134-44. doi: 10.1177/1540415318803947..
Keywords: Quality of Life, Racial and Ethnic Minorities
Skolasky RL, Scherer EA, Wegener ST
Does reduction in sciatica symptoms precede improvement in disability and physical health among those treated surgically for intervertebral disc herniation? Analysis of temporal patterns in data from the Spine Patient Outcomes Research Trial.
This study aimed to evaluate pathways for improvements in quality of life during the first year after surgery for IDH by studying temporal relationships between sciatica symptoms, pain-related disability, and physical health. Investigators found that three months after surgery, patients reported reduced sciatica and pain-related disability. Early reduction in pain-related disability is important because path analysis indicated that disability at 3 months was predictive of sciatica and physical health at 1 year.
AHRQ-funded; HS017990; HS016106.
Citation: Skolasky RL, Scherer EA, Wegener ST .
Does reduction in sciatica symptoms precede improvement in disability and physical health among those treated surgically for intervertebral disc herniation? Analysis of temporal patterns in data from the Spine Patient Outcomes Research Trial.
Spine J 2018 Aug;18(8):1318-24. doi: 10.1016/j.spinee.2017.11.016.
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Keywords: Disabilities, Outcomes, Pain, Patient-Centered Outcomes Research, Quality of Life, Surgery
Badawy SM, Barrera L, Cai S
Association between participants' characteristics, patient-reported outcomes, and clinical outcomes in youth with sickle cell disease.
Researchers studied the effects of sickle disease (SCD) on the quality of life (QOL) on youths with the disease. Participant characteristics, chronic pain, and medication adherence were measured against clinical outcomes. Older and female participants had worse QOL than males overall.
AHRQ-funded; HS023011.
Citation: Badawy SM, Barrera L, Cai S .
Association between participants' characteristics, patient-reported outcomes, and clinical outcomes in youth with sickle cell disease.
Biomed Res Int 2018 Jul 18;2018:8296139. doi: 10.1155/2018/8296139..
Keywords: Children/Adolescents, Outcomes, Patient-Centered Outcomes Research, Quality of Life, Sickle Cell Disease
Taylor YJ, Tapp H, Shade LE
Impact of shared decision making on asthma quality of life and asthma control among children.
This study evaluated the impact of shared decision making (SDM) on quality of life and symptom control in children with asthma. The investigators found that implementation of SDM within clinical practices using a standardized toolkit was associated with improved asthma quality of life and asthma control for low-income children with asthma when compared to usual care with decision support.
AHRQ-funded; HS019946.
Citation: Taylor YJ, Tapp H, Shade LE .
Impact of shared decision making on asthma quality of life and asthma control among children.
J Asthma 2018 Jun;55(6):675-83. doi: 10.1080/02770903.2017.1362423..
Keywords: Children/Adolescents, Asthma, Respiratory Conditions, Chronic Conditions, Shared Decision Making, Quality of Life
Hudson KE, Wolf SP, Samsa GP
The surprise question and identification of palliative care needs among hospitalized patients with advanced hematologic or solid malignancies.
Little is known about quality of life (QOL), depression, and end-of-life (EOL) outcomes among hospitalized patients with advanced cancer. The objective of this study was to assess whether a surprise question identified inpatients with advanced cancer likely to have unmet palliative care needs. The investigators indicated that hospitalized patients with advanced cancer may benefit from palliative care interventions to improve mood, QOL, and EOL care, and the surprise question is a practical method to identify those with unmet needs.
AHRQ-funded; HS023681.
Citation: Hudson KE, Wolf SP, Samsa GP .
The surprise question and identification of palliative care needs among hospitalized patients with advanced hematologic or solid malignancies.
J Palliat Med 2018 Jun;21(6):789-95. doi: 10.1089/jpm.2017.0509..
Keywords: Palliative Care, Cancer, Inpatient Care, Quality of Life, Depression, Behavioral Health
Wu S, Leff B
Frailty measurement and its contribution to clinical care and health services: a commentary.
Frailty is associated with poorer quality of life and higher healthcare utilization and spending. Despite its importance, no clear consensus exists on the definition of frailty. The recent IJHPR article by Buch et al. significantly contributes to the advancement of Israel's understanding of frailty by estimating for the first time the prevalence of frailty in the country. This commentary discusses the context of past and current advancements in measuring frailty and discusses how frailty measurement can contribute to both clinical care and the organization of health services to care for frail older adults in Israel and other developed countries.
AHRQ-funded; HS000029.
Citation: Wu S, Leff B .
Frailty measurement and its contribution to clinical care and health services: a commentary.
Isr J Health Policy Res 2018 May 23;7(1):27. doi: 10.1186/s13584-018-0225-0.
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Keywords: Elderly, Health Services Research (HSR), Quality of Life
Roy B, Riley C, Herrin J
Identifying county characteristics associated with resident well-being: a population based study.
The authors aimed to identify county attributes that are independently associated with a comprehensive, multi-dimensional assessment of individual well-being. They identified twelve county-level factors that were independently associated with individual well-being scores. Collectively, these twelve factors explained 91% of the variance in individual well-being scores, and they represent four conceptually distinct categories: demographic; social and economic; clinical care; and physical environment.
AHRQ-funded; HS023000.
Citation: Roy B, Riley C, Herrin J .
Identifying county characteristics associated with resident well-being: a population based study.
PLoS One 2018 May 23;13(5):e0196720. doi: 10.1371/journal.pone.0196720.
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Keywords: Health Status, Quality of Life, Social Determinants of Health
McCreedy EM, Weinstein BE, Chodosh J
Hearing loss: why does it matter for nursing homes?
This paper examines the impact of hearing loss on residents in nursing home settings and provides an estimate of prevalence using the Minimum Data Set (MDS v.3.0). They outline steps to mitigate hearing loss and discuss solutions that may be inexpensive and low-tech.
AHRQ-funded; HS000011.
Citation: McCreedy EM, Weinstein BE, Chodosh J .
Hearing loss: why does it matter for nursing homes?
J Am Med Dir Assoc 2018 Apr;19(4):323-27. doi: 10.1016/j.jamda.2017.12.007..
Keywords: Nursing Homes, Elderly, Quality of Life, Depression, Behavioral Health
Vakharia PP, Chopra R, Sacotte R
Severity strata for five patient-reported outcomes in adults with atopic dermatitis.
Several patient-reported outcomes have been used to assess the burden of atopic dermatitis (AD). Some are disease specific, such as the Patient-Oriented Eczema Measure (POEM), while others pertain to itch, for example the numerical rating scale (NRS)-itch, ItchyQoL and 5-D itch, or dermatological disease in general, for example the Dermatology Life Quality Index (DLQI). The purpose of this study was to confirm previously developed strata for POEM, DLQI and raw ItchyQoL, and develop strata for the NRS-itch, mean ItchyQoL and 5-D itch scale for use in adults with AD.
AHRQ-funded; HS023011.
Citation: Vakharia PP, Chopra R, Sacotte R .
Severity strata for five patient-reported outcomes in adults with atopic dermatitis.
Br J Dermatol 2018 Apr;178(4):925-30. doi: 10.1111/bjd.16078..
Keywords: Outcomes, Patient-Centered Outcomes Research, Quality of Life, Skin Conditions
Bush RA, Beaumont JL, Liotta EM
Fever burden and health-related quality of life after intracerebral hemorrhage.
In this prospective observational cohort study, the investigators tested the hypothesis that increased burden of fever is independently associated with decreased health-related quality of life (HRQoL) at follow-up. The authors found that each additional day with a fever was predictive of worse HRQoL domains of Cognitive Function and Mobility after intracerebral hemorrhage up to 1 year. They suggest that HRQoL outcomes may be a sensitive and powerful way to measure the efficacy of fever control in future research.
AHRQ-funded; HS023437.
Citation: Bush RA, Beaumont JL, Liotta EM .
Fever burden and health-related quality of life after intracerebral hemorrhage.
Neurocrit Care 2018 Mar 29;29(2):189-94. doi: 10.1007/s12028-018-0523-y..
Keywords: Brain Injury, Neurological Disorders, Outcomes, Patient-Centered Outcomes Research, Quality of Life
Khan S, Biju A, Wang S
Mobile critical care recovery program (m-CCRP) for acute respiratory failure survivors: study protocol for a randomized controlled trial.
The Mobile Critical Care Recovery Program (m-CCRP) study is a two arm, randomized clinical trial. The researchers will randomize 620 patients admitted to the ICU with acute respiratory failure requiring mechanical ventilation to one of two arms - m-CCRP intervention versus attention control. Their primary aim is to assess the efficacy of m-CCRP in improving the quality of life of acute respiratory failure survivors at 12 months
AHRQ-funded; HS024384.
Citation: Khan S, Biju A, Wang S .
Mobile critical care recovery program (m-CCRP) for acute respiratory failure survivors: study protocol for a randomized controlled trial.
Trials 2018 Feb 7;19(1):94. doi: 10.1186/s13063-018-2449-2.
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Keywords: Critical Care, Intensive Care Unit (ICU), Quality of Life, Respiratory Conditions, Respiratory Conditions
Dickerson JF, Feeny DH, Clarke GN
Evidence on the longitudinal construct validity of major generic and utility measures of health-related quality of life in teens with depression.
This study examined the longitudinal construct validity in the assessment of changes in depressive symptoms of widely used utility and generic health-related quality of life (HRQL) instruments in teens. Its findings support the longitudinal construct validity of included HRQL instruments for the assessment of change in depression outcomes in teens.
AHRQ-funded; HS017720.
Citation: Dickerson JF, Feeny DH, Clarke GN .
Evidence on the longitudinal construct validity of major generic and utility measures of health-related quality of life in teens with depression.
Qual Life Res 2018 Feb;27(2):447-54. doi: 10.1007/s11136-017-1728-9.
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Keywords: Children/Adolescents, Depression, Genetics, Quality of Life
Greenhawt M, Oppenheimer JJ
Is the better part of valor truly discretion?
The authors argue that the current model for managing peanut allergy is broken, and this fracture is hallmarked by the rapid increase in poor quality of life and poor empowerment of patients. The risk of fatality is often overblown in the face of data that suggest food allergy fatality is exceedingly low. However, the horizon is bright for future therapies and additional risk modeling, which can better arm decision making and means to inform patients about how to personalize management of their food allergy going forward.
AHRQ-funded; HS024599.
Citation: Greenhawt M, Oppenheimer JJ .
Is the better part of valor truly discretion?
Ann Allergy Asthma Immunol 2018 Feb;120(2):111-12. doi: 10.1016/j.anai.2017.11.003.
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Keywords: Shared Decision Making, Mortality, Patient-Centered Outcomes Research, Patient Self-Management, Quality of Life
Yanez BR, Buitrago D, Buscemi J
Study design and protocol for My Guide: an e-health intervention to improve patient-centered outcomes among Hispanic breast cancer survivors.
This article describes a randomized controlled trial designed to investigate the feasibility and efficacy of a Smartphone application intended to improve health-related quality of life (HRQoL) among Hispanic breast cancer survivors. Participants are randomized to receive either the intervention application My Guide, or the health education control condition application My Health for six weeks, and also receive weekly telecoaching to enhance adherence to both applications. The study's outcomes are measured prior to intervention, immediately after, and eight weeks following initial application use.
AHRQ-funded; HS023011.
Citation: Yanez BR, Buitrago D, Buscemi J .
Study design and protocol for My Guide: an e-health intervention to improve patient-centered outcomes among Hispanic breast cancer survivors.
Contemp Clin Trials 2018 Feb;65:61-68. doi: 10.1016/j.cct.2017.11.018..
Keywords: Cancer, Cancer: Breast Cancer, Health Information Technology (HIT), Outcomes, Patient-Centered Healthcare, Patient-Centered Outcomes Research, Quality of Life, Racial and Ethnic Minorities, Women
Roydhouse JK, Gutman R, Keating NL
Proxy and patient reports of health-related quality of life in a national cancer survey.
The objective of this study was to evaluate the difference between patient and proxy reports of patient HRQOL in a large national cancer survey, and determine if this difference could be mitigated by adjusting for clinical and sociodemographic information about patients. It concluded that the proxy-reported outcome scores for both physical and mental health were clinically and significantly lower than patient-reported scores for these outcomes.
AHRQ-funded; HS000011.
Citation: Roydhouse JK, Gutman R, Keating NL .
Proxy and patient reports of health-related quality of life in a national cancer survey.
Health Qual Life Outcomes 2018 Jan 5;16(1):6. doi: 10.1186/s12955-017-0823-5.
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Keywords: Cancer, Quality of Life, Patient-Centered Healthcare, Patient-Centered Outcomes Research, Behavioral Health
Prescott HC, Costa DK
Improving long-term outcomes after sepsis.
This study discusses how to improve long term outcomes after sepsis and asserts that to improve long-term outcomes, in-hospital care should focus on early, effective treatment of sepsis; minimization of delirium, distress, and immobility; and preparing patients for hospital discharge.
AHRQ-funded; HS024552.
Citation: Prescott HC, Costa DK .
Improving long-term outcomes after sepsis.
Crit Care Clin 2018 Jan;34(1):175-88. doi: 10.1016/j.ccc.2017.08.013..
Keywords: Outcomes, Quality of Life, Sepsis