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Topics
- Adverse Drug Events (ADE) (1)
- Adverse Events (2)
- Antibiotics (1)
- Anxiety (1)
- Behavioral Health (2)
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- (-) Children/Adolescents (14)
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- Outcomes (2)
- (-) Pregnancy (14)
- Prevention (2)
- Racial and Ethnic Minorities (1)
- Screening (2)
- Sex Factors (1)
- Sexual Health (2)
- Shared Decision Making (1)
- Social Stigma (1)
- Stress (1)
- U.S. Preventive Services Task Force (USPSTF) (2)
- Women (6)
- Young Adults (2)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 14 of 14 Research Studies DisplayedPineles BL, Harris AD, Goodman KE
Adverse maternal and delivery outcomes in children and very young (age ≤13 years) US adolescents compared with older adolescents and adults.
This study compared adverse maternal and delivery outcomes of pregnant 10- to 13-year-olds vs 14- to 17-year-olds and 18- to 19-year-olds. This cross-sectional study looked at all patients aged 10 to 19 years who delivered at hospitals in the Premier Healthcare Database from January 2019 through May 2021. The study included 90,876 deliveries across 655 US hospitals. Controlling for patient race and ethnicity, insurance type, and obesity status: 10- to 13-year-olds had significantly higher risks of preterm delivery and cesarean delivery compared with 14- to 17-year-olds. The risk of preeclampsia was not higher for 10- to 13-year-olds compared to 14- to 17-year-olds. There was a higher risk of preterm delivery for 10- to 13-year-olds compared to 18- to 19-year-olds, but not significantly different for cesarean delivery and preeclampsia.
AHRQ-funded; HS028363.
Citation: Pineles BL, Harris AD, Goodman KE .
Adverse maternal and delivery outcomes in children and very young (age ≤13 years) US adolescents compared with older adolescents and adults.
JAMA 2022 Nov 1;328(17):1766-68. doi: 10.1001/jama.2022.18340..
Keywords: Children/Adolescents, Pregnancy, Labor and Delivery, Women, Outcomes, Adverse Events, Maternal Care
Wesemann DG, Wilson AC, Riley AR
Parental cannabis use, negative parenting, and behavior problems of young children.
This cross-sectional survey of parents of young children aged 1.5-5 years examined whether cannabis use is associated with increased risk for negative parenting and child emotional and behavioral problems. The parents reported on family demographics, last 6-months cannabis use, negative parenting, parent mental health, parents' adverse childhood experiences (ACEs), and child emotional/behavioral problems. Of 266 responding parents from five primary care practices in three states, 34 (13%) reported cannabis use in the last 6 months. Those parents who endorsed cannabis use reported significantly more negative parenting, ACEs, anxiety, depression, and child emotional/behavioral problems. However, parental cannabis use did not predict child emotional/behavioral problems when other risk factors were considered. The authors call for further research.
AHRQ-funded; HS022981.
Citation: Wesemann DG, Wilson AC, Riley AR .
Parental cannabis use, negative parenting, and behavior problems of young children.
Subst Use Misuse 2022;57(13):2015-19. doi: 10.1080/10826084.2022.2130001..
Keywords: Children/Adolescents, Behavioral Health, Pregnancy
Ing C, Landau R, DeStephano D
Prenatal exposure to general anesthesia and childhood behavioral deficit.
This study looked at the association of prenatal exposure to general anesthesia and childhood behavioral deficits. The Raine Study was an observational cohort study of children born in Perth, Western Australia with 2 generations of participations. The first generation (Gen1) were mothers enrolled during pregnancy, and the second generation (Gen2) were the children born from 1989 to 1992 with neuropsychological and behavioral tests evaluated at age 10. Six neuropsychological and behavioral tests were used with the Child Behavior Checklist (CBCL) as the main test. Among 2024 children with available outcome scores, 22 were prenatally exposed to general anesthesia. These children had higher CBCL Externalizing behavioral scores than unexposed children. Of the six tests used, only CBCL Externalizing behavioral scores remained significant after multiple comparisons adjustment.
AHRQ-funded; HS026493.
Citation: Ing C, Landau R, DeStephano D .
Prenatal exposure to general anesthesia and childhood behavioral deficit.
Anesth Analg 2021 Sep 1;133(3):595-605. doi: 10.1213/ane.0000000000005389..
Keywords: Children/Adolescents, Behavioral Health, Pregnancy, Adverse Drug Events (ADE), Adverse Events
Schwartz GL, Leifheit KM, Berkman LF
Health selection into eviction: adverse birth outcomes and children's risk of eviction through age 5 years.
Adverse birth outcomes put children at increased risk of poor future health. They also put families under sudden socioeconomic and psychological strain, which has poorly understood consequences. In this study, the investigators tested whether infants experiencing an adverse birth outcome-low birthweight or prematurity, as well as lengthy hospital stays-were more likely to be evicted in early childhood, through age 5 years.
AHRQ-funded; HS000046.
Citation: Schwartz GL, Leifheit KM, Berkman LF .
Health selection into eviction: adverse birth outcomes and children's risk of eviction through age 5 years.
Am J Epidemiol 2021 Jul;190(7):1260-69. doi: 10.1093/aje/kwab007..
Keywords: Children/Adolescents, Newborns/Infants, Labor and Delivery, Pregnancy
Kahwati LC, Clark R, Berkman N
Screening for bacterial vaginosis in pregnant adolescents and women to prevent preterm delivery: updated evidence report and systematic review for the US Preventive Services Task Force.
Researchers sought to update the evidence on screening and treatment of asymptomatic bacterial vaginosis in pregnancy for the USPSTF. They found that the evidence suggests no difference in the incidence of preterm delivery and related outcomes from treatment for asymptomatic bacterial vaginosis in a general obstetric population but was inconclusive for women with a prior preterm delivery. Maternal adverse events from treatment appear to be infrequent and minor, but the evidence about harms from in utero exposure was inconclusive.
AHRQ-funded; 290201500011I.
Citation: Kahwati LC, Clark R, Berkman N .
Screening for bacterial vaginosis in pregnant adolescents and women to prevent preterm delivery: updated evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2020 Apr 7;323(13):1293-309. doi: 10.1001/jama.2020.0233..
Keywords: U.S. Preventive Services Task Force (USPSTF), Screening, Evidence-Based Practice, Prevention, Women, Children/Adolescents, Pregnancy, Maternal Care, Antibiotics, Medication
Cantor AG, Hendrickson R, Blazina I
Screening for elevated blood lead levels in childhood and pregnancy: updated evidence report and systematic review for the US Preventive Services Task Force.
The purpose of this study was to synthesize evidence on the effects of screening, testing, and treatment for elevated blood lead level in pregnant women and children aged 5 years and younger in the primary care setting to inform the US Preventive Services Task Force. The investigators found that screening questionnaires were not accurate for identifying children with elevated blood lead levels. Additionally, chelating agents in children were not significantly associated with sustained effects on blood level levels but were associated with harms.
AHRQ-funded; 290201500009I.
Citation: Cantor AG, Hendrickson R, Blazina I .
Screening for elevated blood lead levels in childhood and pregnancy: updated evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2019 Apr 16;321(15):1510-26. doi: 10.1001/jama.2019.1004..
Keywords: Children/Adolescents, Evidence-Based Practice, Pregnancy, Prevention, Screening, U.S. Preventive Services Task Force (USPSTF), Women
Haley CA, Brault MA, Mwinga K
Promoting progress in child survival across four African countries: the role of strong health governance and leadership in maternal, neonatal and child health.
The researchers conducted four individual case studies concerning the World Health Organization's African Region Millennium Development Goal #4 (MDG#4) to reduce under-five mortality by two-thirds by 2015. They found that strong health governance and leadership (HGL) was a significant driver of the greater success in Liberia and Zambia compared with Kenya and Zimbabwe. Three aspects of HGL which most consistently contributed to the different progress towards MDG#4 among the four study countries were identified. Although child mortality in sub-Saharan Africa remains high, the authors concluded that comparative study suggests key HGL factors that can facilitate the reduction of child mortality and may prove useful in tackling current Sustainable Development Goals.
AHRQ-funded; HS023000.
Citation: Haley CA, Brault MA, Mwinga K .
Promoting progress in child survival across four African countries: the role of strong health governance and leadership in maternal, neonatal and child health.
Health Policy Plan 2019 Feb 1;34(1):24-36. doi: 10.1093/heapol/czy105..
Keywords: Children/Adolescents, Maternal Care, Mortality, Newborns/Infants, Pregnancy
Danilack VA, Brousseau EC, Phipps MG
The effect of gestational weight gain on persistent increase in body mass index in adolescents: a longitudinal study.
Weight retention after pregnancy is a concern for adolescents who may be entering adulthood at unhealthy weights. In this article, the investigators studied associations between each of three measures: pre-pregnancy body mass index (BMI), gestational weight gain (GWG), and post-pregnancy BMI in a longitudinal follow-up of an adolescent pregnancy study cohort. They concluded that teens experienced an increase in BMI from pre-pregnancy to within 4 years after their first delivery, and this increase was related to GWG.
AHRQ-funded; HS025013.
Citation: Danilack VA, Brousseau EC, Phipps MG .
The effect of gestational weight gain on persistent increase in body mass index in adolescents: a longitudinal study.
J Womens Health 2018 Dec;27(12):1456-58. doi: 10.1089/jwh.2017.6635..
Keywords: Children/Adolescents, Pregnancy, Obesity: Weight Management, Obesity, Women
Sutherland S, Brunwasser SM
Sex differences in vulnerability to prenatal stress: a review of the recent literature.
This review evaluates the degree to which recent studies provide evidence that prenatal maternal stress (PNMS) has a varying effect on child health outcomes depending on the child's biological sex. “Stress” includes negative life events, psychological stress, and established stress biomarkers. A review of 50 peer-reviewed articles revealed that most found evidence of either sex-specific associations or significant PNMS (x) stress interactions for at least one outcome. Sex-dependent effects were strongest in the group of studies that evaluated child neural/nervous system development and temperament.
AHRQ-funded; HS022990.
Citation: Sutherland S, Brunwasser SM .
Sex differences in vulnerability to prenatal stress: a review of the recent literature.
Sex differences in vulnerability to prenatal stress: a review of the recent literature.
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Keywords: Children/Adolescents, Newborns/Infants, Outcomes, Pregnancy, Sex Factors, Stress
Connor KA, Duran G, Faiz-Nassar M
Feasibility of implementing group well baby/well woman dyad care at federally qualified health centers.
The aim of this qualitative study was to assess stakeholder perspectives on the feasibility of implementing Centering Parenting (CP) in federally qualified health centers (FQHCs) in Baltimore. The investigators concluded that perceptions regarding facilitators and barriers to CP implementation in FQHCs were similar to existing group well-child care literature; however the benefit of emphasis on maternal wellness was a unique finding. The investigators suggested that a maternal wellness integration might make CP a particularly desirable model for implementation at FQHCs, but potential systems barriers must be addressed.
AHRQ-funded; HS017596.
Citation: Connor KA, Duran G, Faiz-Nassar M .
Feasibility of implementing group well baby/well woman dyad care at federally qualified health centers.
Acad Pediatr 2018 Jul;18(5):510-15. doi: 10.1016/j.acap.2017.09.011..
Keywords: Caregiving, Children/Adolescents, Education: Patient and Caregiver, Health Promotion, Healthcare Delivery, Maternal Care, Newborns/Infants, Pregnancy, Women
Rice WS, Turan B, Stringer KL
Norms and stigma regarding pregnancy decisions during an unintended pregnancy: development and predictors of scales among young women in the U.S. South.
The researchers sought to create measures of perceived norms and stigma around pregnancy decisions by developing and pre-testing 97 survey items using a mixed methods approach. Their factor analyses revealed four subscales for each pregnancy decision: conditional acceptability, anticipated reactions, stereotypes/misperceptions, and attitudes. Minority women endorsed more negative norms and stigma around adoption.
AHRQ-funded; HS013852.
Citation: Rice WS, Turan B, Stringer KL .
Norms and stigma regarding pregnancy decisions during an unintended pregnancy: development and predictors of scales among young women in the U.S. South.
PLoS One 2017 Mar 22;12(3):e0174210. doi: 10.1371/journal.pone.0174210.
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Keywords: Children/Adolescents, Shared Decision Making, Pregnancy, Social Stigma, Young Adults
Upadhya KK, Jalazo ER, Connor KA
AHRQ Author: Mistry KB
Optimizing preconception health among young women: what are we missing?
This study evaluated whether receipt of specific preconception counseling topics differs between teen, young adult, and older mothers. It found that teen mothers were less than half as likely to be counseled about taking folic acid, 4 times more likely to be counseled about vaccines, and twice as likely to be counseled about mental health before pregnancy compared with adult mothers.
AHRQ-authored.
Citation: Upadhya KK, Jalazo ER, Connor KA .
Optimizing preconception health among young women: what are we missing?
J Pediatr Adolesc Gynecol 2016 Oct;29(5):464-6. doi: 10.1016/j.jpag.2016.02.010.
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Keywords: Children/Adolescents, Sexual Health, Maternal Care, Pregnancy, Women, Young Adults
Morales-Aleman MM, Scarinci IC
Correlates and predictors of sexual health among adolescent Latinas in the United States: a systematic review of the literature, 2004-2015.
The authors conducted a systematic literature review to better understand the correlates and predictors of sexual health among adolescent Latinas in the US. They found that results varied widely between studies, suggesting that the relationship between individual and proximal contextual variables and sexual health may be more complex than previously thought. They concluded that their review integrates the findings on correlates and predictors of sexual health among adolescent Latinas, and supports the need for strengths-based theoretically guided research on the mechanisms driving these associations.
AHRQ-funded; HS013852.
Citation: Morales-Aleman MM, Scarinci IC .
Correlates and predictors of sexual health among adolescent Latinas in the United States: a systematic review of the literature, 2004-2015.
Prev Med 2016 Jun;87:183-93. doi: 10.1016/j.ypmed.2016.03.005.
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Keywords: Children/Adolescents, Racial and Ethnic Minorities, Pregnancy, Racial and Ethnic Minorities, Sexual Health
Johnco C, Lewin AB, Salloum A
Adverse prenatal, perinatal and neonatal experiences in children with anxiety disorders.
The authors examined the incidence of adverse prenatal, perinatal, and neonatal experiences among children with anxiety disorders. They found several associations between neonatal complications and subsequent clinical symptomology, including attention deficit hyperactivity disorder and depressive comorbidity, anxiety severity and functional impairment.
AHRQ-funded; HS018665.
Citation: Johnco C, Lewin AB, Salloum A .
Adverse prenatal, perinatal and neonatal experiences in children with anxiety disorders.
Child Psychiatry Hum Dev 2016 Apr;47(2):317-25. doi: 10.1007/s10578-015-0569-4.
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Keywords: Anxiety, Children/Adolescents, Disabilities, Pregnancy