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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 2 of 2 Research Studies DisplayedAuty SG, Daw JR, Admon LK
Comparing approaches to identify live births using the Transformed Medicaid Statistical Information System.
The objective of this study was to evaluate the performance of five approaches to identifying live births using Transformed Medicaid Statistical Information System Analytic Files (TAF). The approaches each used a different combination of diagnosis and procedure, revenue, and place of service codes to identify live births. The findings showed that Approach 4 achieved the best match of birth counts relative to CDC birth record data; Approaches 1 and 3 resulted in overcounts of births and Approaches 2 and 5 resulted in undercounts. The authors concluded that including claims from both inpatient and other services files, and excluding codes unrelated to the delivery episode, improved accuracy of live birth identification in the TAF data.
AHRQ-funded; HS028754; HS027640.
Citation: Auty SG, Daw JR, Admon LK .
Comparing approaches to identify live births using the Transformed Medicaid Statistical Information System.
Health Serv Res 2024 Feb; 59(1):e14233. doi: 10.1111/1475-6773.14233..
Keywords: Medicaid, Research Methodologies
Kyler KE, Hall M, Antoon JW
Major drug-drug interaction exposure among Medicaid-insured children in the outpatient setting.
This study’s objective was to determine the prevalence of major drug-drug interactions (DDI) exposure and factors associated with higher DDI exposure rates among children in an outpatient setting. The authors performed a cross-sectional study of children aged 0 to 18 years with ≥1 ambulatory encounter, and ≥2 dispensed outpatient prescriptions using the 2019 Marketscan Medicaid database. Primary outcomes were the prevalence and rate of major DDI exposure. Out of 781,019 children with ≥2 medication exposures, 21.4% experienced ≥1 major DDI exposure. The odds of exposure increased with age and with medical and mental health complexity. Frequently mentioned drugs included Clonidine, psychiatric medications, and asthma medications. The highest adverse physiologic effect exposure rate per 100 children included: increased drug concentrations (14.6), central nervous system depression (13.6), and heart rate-corrected QT interval prolongation (9.9).
AHRQ-funded; HS028979.
Citation: Kyler KE, Hall M, Antoon JW .
Major drug-drug interaction exposure among Medicaid-insured children in the outpatient setting.
Pediatrics 2024 Jan; 153(2):e2023063506. doi: 10.1542/peds.2023-063506.
Keywords: Children/Adolescents, Adverse Drug Events (ADE), Adverse Events, Medicaid, Medication: Safety