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AHRQ Research Studies Date
Topics
- Adverse Drug Events (ADE) (2)
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 13 of 13 Research Studies DisplayedHeslin KC, Owens PL, Karaca Z
AHRQ Author: Heslin KC; Owens PL; Karaca Z; Elixhauser A
Trends in opioid-related inpatient stays shifted after the US transitioned to ICD-10-CM diagnosis coding in 2015.
This study examines how trend analyses of inpatient stays involving opioid diagnoses were affected by the transition to ICD-10-CM. It found a sharp increase in opioid-related stays overall during the transition to ICD-10-CM. This may indicate that the new classification system is capturing stays that were missed by ICD-9-CM data.
AHRQ-authored.
Citation: Heslin KC, Owens PL, Karaca Z .
Trends in opioid-related inpatient stays shifted after the US transitioned to ICD-10-CM diagnosis coding in 2015.
Med Care 2017 Nov;55(11):918-23. doi: 10.1097/mlr.0000000000000805.
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Keywords: Critical Care, Healthcare Cost and Utilization Project (HCUP), Hospitalization, Opioids, Substance Abuse
Tedesco D, Asch SM, Curtin C
Opioid abuse and poisoning: trends in inpatient and emergency department discharges.
This study analyzed national trends in inpatient and emergency department (ED) discharges for opioid abuse, dependence, and poisoning using Healthcare Cost and Utilization Project data.
AHRQ-funded; HS024096.
Citation: Tedesco D, Asch SM, Curtin C .
Opioid abuse and poisoning: trends in inpatient and emergency department discharges.
Health Aff 2017 Oct;36(10):1748-53. doi: 10.1377/hlthaff.2017.0260..
Keywords: Emergency Department, Healthcare Cost and Utilization Project (HCUP), Hospital Discharge, Opioids, Substance Abuse
Balbale SN, Trivedi I, O'Dwyer LC
Strategies to identify and reduce opioid misuse among patients with gastrointestinal disorders: a systematic scoping review.
In this study, the investigators conducted a systematic scoping review to describe published scientific literature on strategies to identify and reduce opioid misuse among patients with gastrointestinal (GI) symptoms and disorders. They concluded that prescription drug monitoring and self-management interventions may be promising strategies to identify and reduce opioid misuse in GI care. They suggest that rigorous, empirical research is needed to evaluate the longer-term impact of these strategies.
AHRQ-funded; HS000084.
Citation: Balbale SN, Trivedi I, O'Dwyer LC .
Strategies to identify and reduce opioid misuse among patients with gastrointestinal disorders: a systematic scoping review.
Dig Dis Sci 2017 Oct;62(10):2668-85. doi: 10.1007/s10620-017-4705-9..
Keywords: Behavioral Health, Chronic Conditions, Digestive Disease and Health, Medication, Medication: Safety, Opioids, Patient Self-Management, Prevention, Substance Abuse
Chhatre S, Cook R, Mallik E
Trends in substance use admissions among older adults.
Researchers sought to analyze the trends in admissions for substance abuse treatment among older adults (aged 55 and older). Substantial changes in the demographic, substance use pattern, and treatment characteristics for the older adult admissions were noted. The proportion of admissions for following primary substances showed increase: cocaine/crack, marijuana/hashish, heroin, non-prescription methadone, and other opiates and synthetics.
AHRQ-funded; HS024106.
Citation: Chhatre S, Cook R, Mallik E .
Trends in substance use admissions among older adults.
BMC Health Serv Res 2017 Aug 22;17(1):584. doi: 10.1186/s12913-017-2538-z.
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Keywords: Behavioral Health, Elderly, Hospitalization, Opioids, Substance Abuse
Horton M, McDonald R, Green TC
A mapping review of take-home naloxone for people released from correctional settings.
The objective of this review is to map research into take-home naloxone (THN) for people released from correctional settings in order to identify further research needs. It concluded that the feasibility of THN in the context of release from a correctional setting has been established, but there is a need for rigorous research into health outcomes and program implementation.
AHRQ-funded; HS024021.
Citation: Horton M, McDonald R, Green TC .
A mapping review of take-home naloxone for people released from correctional settings.
Int J Drug Policy 2017 Aug;46:7-16. doi: 10.1016/j.drugpo.2017.05.015.
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Keywords: Adverse Drug Events (ADE), Medication, Opioids, Substance Abuse, Vulnerable Populations
Carroll JJ, Marshall BDL, Rich JD
Exposure to fentanyl-contaminated heroin and overdose risk among illicit opioid users in Rhode Island: a mixed methods study.
This study describes patterns and perceptions of fentanyl exposure among opioid users in Rhode Island. It concluded that among illicit opioid users in Rhode Island, known or suspected fentanyl exposure is common, yet demand for fentanyl is low. Fentanyl-contaminated drugs are generating user interest in effective risk mitigation strategies, including treatment.
AHRQ-funded; HS024021.
Citation: Carroll JJ, Marshall BDL, Rich JD .
Exposure to fentanyl-contaminated heroin and overdose risk among illicit opioid users in Rhode Island: a mixed methods study.
Int J Drug Policy 2017 Aug;46:136-45. doi: 10.1016/j.drugpo.2017.05.023.
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Keywords: Opioids, Substance Abuse, Medication, Adverse Drug Events (ADE)
Olfson M, Wall M, Wang S
Service use preceding opioid-related fatality.
The authors analyzed health service patterns before opioid-related death among nonelderly individuals in the Medicaid program, focusing on decedents with and without past-year diagnoses of non-cancer chronic pain. They found that persons dying of opioid-related causes, particularly those who were diagnosed with chronic pain conditions, commonly received services related to drug use disorders and mental disorders in the last year of life, though opioid use disorder diagnoses near the time of death were rare.
AHRQ-funded; HS021112.
Citation: Olfson M, Wall M, Wang S .
Service use preceding opioid-related fatality.
Am J Psychiatry 2017 Jun;175(6):538-44. doi: 10.1176/appi.ajp.2017.17070808.
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Keywords: Chronic Conditions, Opioids, Medicaid, Mortality, Substance Abuse
Kozhimannil KB, Graves AJ, Jarlenski M
Non-medical opioid use and sources of opioids among pregnant and non-pregnant reproductive-aged women.
This study characterized non-medical use (NMU) of prescription opioids among reproductive-age U.S. women, with a focus on pregnancy status. Nearly 1 percent of pregnant women and 2.3 percent of non-pregnant reproductive-age women reported opioid NMU in the past 30 days. Forty-six percent of pregnant women identified a doctor as their source compared with 27.6 percent of non-pregnant women reporting NMU.
AHRQ-funded; HS000029.
Citation: Kozhimannil KB, Graves AJ, Jarlenski M .
Non-medical opioid use and sources of opioids among pregnant and non-pregnant reproductive-aged women.
Drug Alcohol Depend 2017 May 1;174:201-08. doi: 10.1016/j.drugalcdep.2017.01.003.
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Keywords: Medication, Opioids, Pregnancy, Substance Abuse, Women
Macmadu A, Carroll JJ, Hadland SE
Prevalence and correlates of fentanyl-contaminated heroin exposure among young adults who use prescription opioids non-medically.
Researchers examined risk factors for exposure to fentanyl-contaminated heroin (FCH) and experiences with FCH use among young adult non-medical prescription opioids (NMPO) users. Several drug use patterns and risk behaviors were associated with FCH exposure, including: regular heroin and cocaine use; diverted pharmaceutical fentanyl use in the prior six months; NMPO use to avoid withdrawal symptoms; regular injection drug use; and prior overdose.
AHRQ-funded; HS024021.
Citation: Macmadu A, Carroll JJ, Hadland SE .
Prevalence and correlates of fentanyl-contaminated heroin exposure among young adults who use prescription opioids non-medically.
Addict Behav 2017 May;68:35-38. doi: 10.1016/j.addbeh.2017.01.014.
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Keywords: Opioids, Medication, Risk, Substance Abuse, Young Adults
Kennedy-Hendricks A, Barry CL, Gollust SE
Social stigma toward persons with prescription opioid use disorder: associations with public support for punitive and public health-oriented policies.
This study examined social stigma toward individuals with prescription opioid use disorder and tested whether stigma was associated with support for various policy interventions. Respondents expressed high levels of stigma toward individuals with prescription opioid use disorder. Higher levels of stigma were associated with greater support for punitive policies and lower support for public health-oriented policies.
AHRQ-funded; HS000029.
Citation: Kennedy-Hendricks A, Barry CL, Gollust SE .
Social stigma toward persons with prescription opioid use disorder: associations with public support for punitive and public health-oriented policies.
Psychiatr Serv 2017 May;68(5):462-69. doi: 10.1176/appi.ps.201600056.
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Keywords: Medication, Opioids, Policy, Social Stigma, Substance Abuse
Green TC, Case P, Fiske H
Perpetuating stigma or reducing risk? Perspectives from naloxone consumers and pharmacists on pharmacy-based naloxone in 2 states.
This study examined perceptions and experiences of pharmacy naloxone from people with opioid use disorder, patients taking chronic opioids for pain, caregivers of opioid users, and pharmacists. It found that consumer groups differed in awareness of naloxone and availability at pharmacies, but all groups expressed support for the pharmacist's role and preferences for a universal offer of naloxone based on clear criteria.
AHRQ-funded; HS024021.
Citation: Green TC, Case P, Fiske H .
Perpetuating stigma or reducing risk? Perspectives from naloxone consumers and pharmacists on pharmacy-based naloxone in 2 states.
J Am Pharm Assoc 2017 Mar - Apr;57(2s):S19-S27.e4. doi: 10.1016/j.japh.2017.01.013.
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Keywords: Opioids, Provider: Pharmacist, Social Stigma, Substance Abuse
Korthuis PT, McCarty D, Weimer M
Primary care-based models for the treatment of opioid use disorder: a scoping review.
This article summarizes findings of a technical report for AHRQ describing medication-assisted treatment (MAT) models of care for opioid use disorder, based on a literature review and interviews with key informants in the field. The report describes 12 representative models of care for integrating MAT into primary care settings that could be considered for adaptation across diverse health care settings.
AHRQ-funded; 290201500009I.
Citation: Korthuis PT, McCarty D, Weimer M .
Primary care-based models for the treatment of opioid use disorder: a scoping review.
Ann Intern Med 2017 Feb 21;166(4):268-78. doi: 10.7326/m16-2149.
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Keywords: Opioids, Primary Care, Primary Care: Models of Care, Substance Abuse, Medication
Parchman ML, Von Korff M, Baldwin LM
Primary care clinic re-design for prescription opioid management.
The researchers describe a framework comprised of 6 Building Blocks to guide efforts within the primary care clinic setting to address the use of opioids for chronic pain. In response to prescription opioid overuse and the resulting epidemic of overdose and addiction, primary care clinics are making improvements driven by a common set of best practices that address complex challenges of managing chronic opioid therapy patients in primary care settings.
AHRQ-funded; HS023750.
Citation: Parchman ML, Von Korff M, Baldwin LM .
Primary care clinic re-design for prescription opioid management.
J Am Board Fam Med 2017 Jan-Feb;30(1):44-51. doi: 10.3122/jabfm.2017.01.160183.
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Keywords: Chronic Conditions, Opioids, Pain, Substance Abuse, Teams