National Healthcare Quality and Disparities Report
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AHRQ Research Studies Date
Topics
- Access to Care (1)
- Adverse Drug Events (ADE) (1)
- Adverse Events (1)
- Blood Pressure (1)
- Care Management (1)
- Case Study (1)
- Chronic Conditions (3)
- Comparative Effectiveness (2)
- (-) Diabetes (22)
- Diagnostic Safety and Quality (1)
- Electronic Health Records (EHRs) (1)
- Evidence-Based Practice (2)
- Guidelines (2)
- Healthcare Utilization (1)
- Health Information Technology (HIT) (3)
- Health Promotion (1)
- Labor and Delivery (1)
- Lifestyle Changes (7)
- Low-Income (1)
- Maternal Care (7)
- Medicaid (1)
- Medical Expenditure Panel Survey (MEPS) (1)
- Medication (2)
- Newborns/Infants (2)
- Nutrition (1)
- Obesity (2)
- Obesity: Weight Management (1)
- Outcomes (3)
- Patient-Centered Healthcare (1)
- Patient-Centered Outcomes Research (3)
- Practice Patterns (1)
- Pregnancy (19)
- Prevention (6)
- Racial and Ethnic Minorities (3)
- Risk (4)
- Screening (5)
- Social Determinants of Health (1)
- Telehealth (1)
- U.S. Preventive Services Task Force (USPSTF) (2)
- (-) Women (22)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 22 of 22 Research Studies DisplayedVenkatesh KK, Grobman WA, Wu J
Association of a large-for-gestational-age infant and maternal prediabetes mellitus and diabetes mellitus 10 to 14 years after delivery in the Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study.
Hypothesizing that having a large-for-gestational-age (LGA) infant even without gestational diabetes mellitus (GDM) may be a precursor to postpartum dysglycemia, researchers estimated the association of having had an LGA infant with developing maternal prediabetes mellitus and type 2 diabetes mellitus after delivery among individuals without GDM. They conducted a secondary analysis of the prospective Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study (HAPO FUS). Their findings suggested that having an LGA infant was associated with a higher risk of prediabetes mellitus or diabetes mellitus by 10 to 14 years
after delivery.
after delivery.
AHRQ-funded; HS028822.
Citation: Venkatesh KK, Grobman WA, Wu J .
Association of a large-for-gestational-age infant and maternal prediabetes mellitus and diabetes mellitus 10 to 14 years after delivery in the Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study.
Am J Obstet Gynecol 2023 Jun; 228(6):756-58.e3. doi: 10.1016/j.ajog.2023.02.017..
Keywords: Newborns/Infants, Maternal Care, Women, Diabetes
Field C, Lynch CD, Fareed N
Association of community walkability and glycemic control among pregnant individuals with pregestational diabetes mellitus.
The role of community walkability in influencing glycemic regulation in expectant individuals with pre-existing diabetes is yet to be established. The purpose of this study was to explore the relationship between the walkability of a neighborhood at the community level and glycemic control, as indicated by hemoglobin A1c (A1C), in pregnant individuals with pregestational diabetes. The researchers conducted a retrospective examination of expectant individuals with pregestational diabetes who participated in a combined prenatal and diabetic care program from 2012 to 2016. The determinant of interest was community walkability, determined by the US Environmental Protection Agency National Walkability Index (score range 1-20), which includes intersection concentration (design), closeness to transit stops (distance), and a combination of job and household varieties (diversity). Participants from the most walkable neighborhoods were contrasted with those from less walkable neighborhoods as per the National Environmental Protection Agency's definition. The outcomes were glycemic control, including A1C, measured both in early and late pregnancy, and the average change in A1C throughout pregnancy. The study found that out of 417 expectant individuals, 10% resided in the most walkable areas. All 417 participants had an A1C assessment in early pregnancy, and 376 had another A1C assessment in late pregnancy. Pregnant individuals living in the most walkable areas were more likely to have an A1C <6.0% in early pregnancy, and an A1C <6.5% in late pregnancy compared with those in less walkable areas. The change in A1C across pregnancy was not related to walkability. The study concluded that individuals with pre-existing diabetes residing in more walkable areas demonstrated better glycemic control during both early and late pregnancy.
AHRQ-funded; HS028822.
Citation: Field C, Lynch CD, Fareed N .
Association of community walkability and glycemic control among pregnant individuals with pregestational diabetes mellitus.
Am J Obstet Gynecol MFM 2023 May; 5(5):100898. doi: 10.1016/j.ajogmf.2023.100898..
Keywords: Diabetes, Maternal Care, Social Determinants of Health, Women
Fareed N, Swoboda C, Singh P
Developing and testing an integrated patient mHealth and provider dashboard application system for type 2 diabetes management among Medicaid-enrolled pregnant individuals based on a user-centered approach: mixed-methods study.
The objective of this study was to develop user specifications for a tailored and integrated technology, patient application (mHealth) and provider dashboard, that provides a complete view of Medicaid-enrolled patients with type 2 diabetes (T2D) during pregnancy and to develop prototypes based on users’ needs. Participating patients and providers stated a core set of expectations for the mHealth and dashboard applications. Participants then provided feedback to improve these applications. The authors concluded that digital health tools could transform health care among Medicaid-enrolled patients with T2D during pregnancy, with the goal of managing their blood glucose levels. Refining the stated needs and preferences of patients and providers to develop applications holds potential for tackling complicated health care issues.
AHRQ-funded; HS028822.
Citation: Fareed N, Swoboda C, Singh P .
Developing and testing an integrated patient mHealth and provider dashboard application system for type 2 diabetes management among Medicaid-enrolled pregnant individuals based on a user-centered approach: mixed-methods study.
Digit Health 2023 Jan-Dec; 9:20552076221144181. doi: 10.1177/20552076221144181..
Keywords: Patient-Centered Healthcare, Telehealth, Diabetes, Pregnancy, Chronic Conditions, Women, Health Information Technology (HIT)
Mills J, Mohnot S
AHRQ Author: Mills J
Screening for gestational diabetes.
This “Putting Prevention into Practice: An Evidence Based Approach” paper is a case study with questions and answers related to a patient with gestational diabetes.
AHRQ-authored.
Citation: Mills J, Mohnot S .
Screening for gestational diabetes.
Am Fam Physician 2021 Dec 1;104(6):641-42..
Keywords: U.S. Preventive Services Task Force (USPSTF), Diabetes, Pregnancy, Screening, Prevention, Women, Evidence-Based Practice, Guidelines, Case Study
Pillay J, Donovan L, Guitard S
Screening for gestational diabetes: updated evidence report and systematic review for the US Preventive Services Task Force.
The objective of this study was to update the 2012 review on screening for gestational diabetes to inform the US Preventive Services Task Force. The investigators concluded that direct evidence on screening vs no screening remained limited. One- vs 2-step screening was not significantly associated with improved health outcomes. At or after 24 weeks of gestation, treatment of gestational diabetes was significantly associated with improved health outcomes.
Citation: Pillay J, Donovan L, Guitard S .
Screening for gestational diabetes: updated evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2021 Aug 10;326(6):539-62. doi: 10.1001/jama.2021.10404..
Keywords: U.S. Preventive Services Task Force (USPSTF), Diabetes, Pregnancy, Screening, Evidence-Based Practice, Women, Prevention, Guidelines
Herrick CJ, Keller MR, Trolard AM
Factors associated with postpartum diabetes screening in women with gestational diabetes and Medicaid during pregnancy.
This study’s goal was to understand the factors associated with the receipt of postpartum diabetes screening for women with gestational diabetes in a state without Medicaid expansion. Findings showed that prenatal certified diabetes education and access to public transportation were associated with increased screening, the total number of prenatal visits, the use of diabetes medication during pregnancy, and a pregnancy-specific comorbidity index that incorporated age.
AHRQ-funded; HS019455.
Citation: Herrick CJ, Keller MR, Trolard AM .
Factors associated with postpartum diabetes screening in women with gestational diabetes and Medicaid during pregnancy.
Am J Prev Med 2021 Feb;60(2):222-31. doi: 10.1016/j.amepre.2020.08.028..
Keywords: Diabetes, Screening, Maternal Care, Pregnancy, Women, Medicaid, Access to Care
Tassone C, Keshavjee K, Paglialonga A
Evaluation of mobile apps for treatment of patients at risk of developing gestational diabetes.
This study evaluated mobile apps using a theory-based evaluation framework to discover their applicability for patients at risk of gestational diabetes. It assessed how well the existing mobile apps on the market met the information and tracking needs of patients with gestational diabetes and evaluated the feasibility of how to integrate these apps into patient care.
AHRQ-funded; HS021495; HS24869.
Citation: Tassone C, Keshavjee K, Paglialonga A .
Evaluation of mobile apps for treatment of patients at risk of developing gestational diabetes.
Health Informatics J 2020 Sep;26(3):1983-94. doi: 10.1177/1460458219896639..
Keywords: Diabetes, Risk, Health Information Technology (HIT), Women
Fabiyi CA, Reid LD, Mistry KB
AHRQ Author: Fabiyi CA, Mistry KB
Postpartum health care use after gestational diabetes and hypertensive disorders of pregnancy.
The objective of this study was to examine postpartum health care utilization after a pregnancy complicated by gestational diabetes (GD) and hypertensive disorders of pregnancy (HDP) using nationally representative data. The investigators found that women with GD/HDP did not differ from women with neither complication on postpartum utilization outcomes. Less educated women with GD/HDP were more likely to miss an office visit within 1 year postpartum than less educated women with neither complication. Certain subgroups of women were more likely to forego timely and appropriate postpartum care.
AHRQ-authored.
Citation: Fabiyi CA, Reid LD, Mistry KB .
Postpartum health care use after gestational diabetes and hypertensive disorders of pregnancy.
J Womens Health 2019 Aug;28(8):1116-23. doi: 10.1089/jwh.2018.7198..
Keywords: Medical Expenditure Panel Survey (MEPS), Maternal Care, Pregnancy, Diabetes, Blood Pressure, Women, Healthcare Utilization
Brown SD, Fotuhi O, Grijalva CS
A randomized study of values affirmation to promote interest in diabetes prevention among women with a history of gestational diabetes.
The purpose of this study was to test whether two interventions promote interest in diabetes prevention among women with a history of gestational diabetes mellitus. The researchers designed an email outreach message incorporating ‘values affirmation,’ a theory-based intervention, and promoting an existing preventive lifestyle program. Selected patients were randomized to read an outreach message containing either no affirmation (control) or 1 of 2 affirmations. Results showed that participants randomized to the values affirmation more frequently demonstrated interest in the lifestyle program and sought information about diabetes prevention, while the parenting affirmation yielded no significant differences in either outcome.
AHRQ-funded; HS019367.
Citation: Brown SD, Fotuhi O, Grijalva CS .
A randomized study of values affirmation to promote interest in diabetes prevention among women with a history of gestational diabetes.
Med Care 2019 Jul;57(7):528-35. doi: 10.1097/mlr.0000000000001133..
Keywords: Diabetes, Chronic Conditions, Pregnancy, Women, Health Promotion, Prevention, Lifestyle Changes
Herrick CJ, Keller MR, Trolard AM
Postpartum diabetes screening among low income women with gestational diabetes in Missouri 2010-2015.
This study looked at postpartum screening for type 2 diabetes among low-income women who were previously diagnosed with gestational diabetes. Gestational diabetes increases risk for developing type 2 diabetes 7-fold so it is recommended that screening is done within months after delivery. Results in a Missouri population found that almost 20% were screened within the first year of delivery.
AHRQ-funded; HS019455.
Citation: Herrick CJ, Keller MR, Trolard AM .
Postpartum diabetes screening among low income women with gestational diabetes in Missouri 2010-2015.
BMC Public Health 2019 Feb 4;19(1):148. doi: 10.1186/s12889-019-6475-0..
Keywords: Diabetes, Low-Income, Pregnancy, Screening, Women
Gadgil MD, Ehrlich SF, Zhu Y
Dietary quality and glycemic control among women with gestational diabetes mellitus.
Poor dietary quality, measured by the Healthy Eating Index 2010 (HEI-2010), is associated with risk of gestational diabetes mellitus (GDM) and type 2 diabetes. The aim was to investigate the association between dietary quality and glycemic control in women with GDM. The authors concluded that clinicians should be aware that even a small improvement in diet quality may be beneficial for the achievement of improved glycemic control in women with GDM.
AHRQ-funded; HS019367.
Citation: Gadgil MD, Ehrlich SF, Zhu Y .
Dietary quality and glycemic control among women with gestational diabetes mellitus.
J Womens Health 2019 Feb;28(2):178-84. doi: 10.1089/jwh.2017.6788..
Keywords: Pregnancy, Diabetes, Nutrition, Women, Risk, Prevention
Hedderson MM, Brown SD, Ehrlich SF
A tailored letter based on electronic health record data improves gestational weight gain among women with gestational diabetes mellitus: the Gestational Diabetes' Effects on Moms (GEM) cluster-randomized controlled trial.
The purpose of this study was to evaluate whether a tailored letter improved gestational weight gain (GWG) and whether GWG mediated a multicomponent intervention's effect on postpartum weight retention among women with gestational diabetes mellitus (GDM). The authors concluded that a tailored electronic health record-based letter improved GWG, which mediated the effect of a multicomponent intervention in reducing postpartum weight retention.
AHRQ-funded; HS019367.
Citation: Hedderson MM, Brown SD, Ehrlich SF .
A tailored letter based on electronic health record data improves gestational weight gain among women with gestational diabetes mellitus: the Gestational Diabetes' Effects on Moms (GEM) cluster-randomized controlled trial.
Diabetes Care 2018 Jul;41(7):1370-77. doi: 10.2337/dc17-1133..
Keywords: Diabetes, Electronic Health Records (EHRs), Health Information Technology (HIT), Lifestyle Changes, Patient-Centered Outcomes Research, Pregnancy, Women
Dickens LT, Naylor RN
Clinical management of women with monogenic diabetes during pregnancy.
This study discusses clinical management of women with monogenic diabetes during pregnancy. Monogenic diabetes is rare and only accounts for 1-2% of all diabetes cases so it is frequently misdiagnoses as one of the other diabetes types. Diabetes treatment is different for this type of diabetes, and if untreated can cause fetal mutations. However, if treated there can be transplacental transfer of the medication (sulfonylurea). The study authors recommend large prospective studies be conducted to better define the need and timing of initiation of insulin treatment.
AHRQ-funded; HS023007.
Citation: Dickens LT, Naylor RN .
Clinical management of women with monogenic diabetes during pregnancy.
Curr Diab Rep 2018 Feb 15;18(3):12. doi: 10.1007/s11892-018-0982-8..
Keywords: Care Management, Chronic Conditions, Diabetes, Maternal Care, Pregnancy, Women
Ehrlich SF, Hedderson MM, Brown SD
Moderate intensity sports and exercise is associated with glycaemic control in women with gestational diabetes.
The aim of the study was to assess the association of regular, unsupervised sports and exercise during pregnancy, by intensity level, with glycaemic control in women with gestational diabetes (GDM). The study concluded that higher volumes of moderate intensity sports and exercise, reported shortly after GDM diagnosis, were significantly associated with increased odds of achieving glycaemic control.
AHRQ-funded; HS019367.
Citation: Ehrlich SF, Hedderson MM, Brown SD .
Moderate intensity sports and exercise is associated with glycaemic control in women with gestational diabetes.
Diabetes Metab 2017 Oct;43(5):416-23. doi: 10.1016/j.diabet.2017.01.006..
Keywords: Diabetes, Lifestyle Changes, Outcomes, Patient-Centered Outcomes Research, Pregnancy, Women
Brown SD, Ehrlich SF, Kubo A
Lifestyle behaviors and ethnic identity among diverse women at high risk for type 2 diabetes.
The authors examined if ethnic identity could help account for variations in lifestyle behaviors within a diverse population at high risk for type 2 diabetes. Their findings suggest that ethnic group attachment is associated with some lifestyle behaviors, independent of acculturation indicators, among young women with gestational diabetes who are at high risk for type 2 diabetes. They suggest that prospective research is needed to clarify the temporal nature of associations between ethnic identity and modifiable diabetes risk factors.
AHRQ-funded; HS019367.
Citation: Brown SD, Ehrlich SF, Kubo A .
Lifestyle behaviors and ethnic identity among diverse women at high risk for type 2 diabetes.
Soc Sci Med 2016 Jul;160:87-93. doi: 10.1016/j.socscimed.2016.05.024.
.
.
Keywords: Diabetes, Lifestyle Changes, Pregnancy, Racial and Ethnic Minorities, Women
Ehrlich SF, Sternfeld B, Krefman AE
Moderate and vigorous intensity exercise during pregnancy and gestational weight gain in women with gestational diabetes.
The researchers estimated the associations of exercise intensity during pregnancy with the rate of gestational weight gain (GWG) from gestational diabetes (GDM) diagnosis to delivery. Upon stratification by prepregnancy overweight/obesity, they found that significant associations were only observed for BMI greater than or equal to 25.0. There were no associations observed for moderate intensity exercise.
AHRQ-funded; HS019367.
Citation: Ehrlich SF, Sternfeld B, Krefman AE .
Moderate and vigorous intensity exercise during pregnancy and gestational weight gain in women with gestational diabetes.
Matern Child Health J 2016 Jun;20(6):1247-57. doi: 10.1007/s10995-016-1926-z.
.
.
Keywords: Diabetes, Lifestyle Changes, Obesity, Obesity: Weight Management, Outcomes, Patient-Centered Outcomes Research, Pregnancy, Women
Ferrara A, Hedderson MM, Brown SD
The comparative effectiveness of diabetes prevention strategies to reduce postpartum weight retention in women with gestational diabetes mellitus: the gestational diabetes' effects on moms (GEM) cluster randomized controlled trial.
The researchers compared the effectiveness of diabetes prevention strategies addressing postpartum weight retention for women with gestational diabetes mellitus (GDM) delivered at the health system level: mailed recommendations (usual care) versus usual care plus a Diabetes Prevention Program (DPP)-derived lifestyle intervention. They found that a DPP-derived lifestyle intervention modestly reduced postpartum weight retention and increased vigorous-intensity physical activity.
AHRQ-funded; HS019367.
Citation: Ferrara A, Hedderson MM, Brown SD .
The comparative effectiveness of diabetes prevention strategies to reduce postpartum weight retention in women with gestational diabetes mellitus: the gestational diabetes' effects on moms (GEM) cluster randomized controlled trial.
Diabetes Care 2016 Jan;39(1):65-74. doi: 10.2337/dc15-1254.
.
.
Keywords: Comparative Effectiveness, Diabetes, Lifestyle Changes, Pregnancy, Prevention, Women
Pu J, Zhao B, Wang EJ
Racial/ethnic differences in gestational diabetes prevalence and contribution of common risk factors.
This study aimed to assess racial/ethnic differences in relative contribution of risk factors of gestational diabetes mellitus (GDM) among Asian subgroups (Asian Indian, Chinese, Filipino, Japanese, Korean, and Vietnamese), Hispanics, non-Hispanic blacks, and non-Hispanic whites. It found that GDM was most prevalent among Asian Indians (19.3 percent). Relative risks were similar across all race/ethnic groups.
AHRQ-funded; HS019815.
Citation: Pu J, Zhao B, Wang EJ .
Racial/ethnic differences in gestational diabetes prevalence and contribution of common risk factors.
Paediatr Perinat Epidemiol 2015 Sep;29(5):436-43. doi: 10.1111/ppe.12209.
.
.
Keywords: Diabetes, Obesity, Pregnancy, Racial and Ethnic Minorities, Risk, Women
Scifres CM, Abebe KZ, Jones KA
Gestational diabetes diagnostic methods (GD2M) pilot randomized trial.
The researchers tested the feasibility of conducting a pragmatic randomized controlled trial (RCT) comparing the International Association of Diabetes in Pregnancy Study Groups (IADPSG) versus Carpenter-Coustan diagnostic criteria for gestational diabetes (GDM), and examined patient and provider views on GDM screening. They found that both pregnant women and providers value GDM screening, and pregnant women can be recruited to a blinded, randomized GDM screening trial with minimal attrition and missing data.
AHRQ-funded; HS019461.
Citation: Scifres CM, Abebe KZ, Jones KA .
Gestational diabetes diagnostic methods (GD2M) pilot randomized trial.
Matern Child Health J 2015 Jul;19(7):1472-80. doi: 10.1007/s10995-014-1651-4..
Keywords: Diabetes, Diagnostic Safety and Quality, Pregnancy, Screening, Women
Tang JW, Foster KE, Pumarino J
Perspectives on prevention of type 2 diabetes after gestational diabetes: a qualitative study of Hispanic, African-American and White women.
This qualitative study explored the perspectives of Hispanic, African-American, and White women affected by gestational diabetes mellitus (GDM). The goal is for this work to inform the development of effective approaches to engage diverse populations affected by GDM in taking steps to reduce their risk for type 2 diabetes mellitus.
AHRQ-funded; HS021141.
Citation: Tang JW, Foster KE, Pumarino J .
Perspectives on prevention of type 2 diabetes after gestational diabetes: a qualitative study of Hispanic, African-American and White women.
Matern Child Health J 2015 Jul;19(7):1526-34. doi: 10.1007/s10995-014-1657-y..
Keywords: Diabetes, Lifestyle Changes, Pregnancy, Prevention, Racial and Ethnic Minorities, Risk, Women
Camelo Castillo W, Boggess K, Sturmer T
Association of adverse pregnancy outcomes with glyburide vs insulin in women with gestational diabetes.
The purpose of this study was to estimate the risks of adverse pregnancy outcomes among women receiving glyburide compared with insulin for the treatment of gestational diabetes mellitus (GDM) in a US population-based cohort. It found an association between glyburide (compared with insulin) and elevated risk of NICU admission, neonatal hypoglycemia, respiratory distress, birth injury, and large for gestational age in women with GDM.
AHRQ-funded; HS017950.
Citation: Camelo Castillo W, Boggess K, Sturmer T .
Association of adverse pregnancy outcomes with glyburide vs insulin in women with gestational diabetes.
JAMA Pediatr 2015 May;169(5):452-8. doi: 10.1001/jamapediatrics.2015.74..
Keywords: Adverse Drug Events (ADE), Adverse Events, Comparative Effectiveness, Diabetes, Labor and Delivery, Maternal Care, Medication, Newborns/Infants, Outcomes, Pregnancy, Women
Camelo Castillo W, Boggess K, Stürmer T
Trends in glyburide compared with insulin use for gestational diabetes treatment in the United States, 2000-2011.
The researchers sought to characterize pharmacologic treatment of women with gestational diabetes (GDM) by describing trends in the use of glyburide compared with insulin over the past decade (2000-2011) and identifying predictors of initial choice of pharmacotherapy. They found that glyburide has replaced insulin as the more common pharmacotherapy for GDM among those privately insured.
AHRQ-funded; HS017950
Citation: Camelo Castillo W, Boggess K, Stürmer T .
Trends in glyburide compared with insulin use for gestational diabetes treatment in the United States, 2000-2011.
Obstet Gynecol. 2014 Jun;123(6):1177-84. doi: 10.1097/AOG.0000000000000285..
Keywords: Diabetes, Maternal Care, Medication, Practice Patterns, Pregnancy, Women