National Healthcare Quality and Disparities Report
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AHRQ Research Studies Date
Topics
- Access to Care (2)
- Anxiety (2)
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- Human Immunodeficiency Virus (HIV) (2)
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- Injuries and Wounds (1)
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- (-) Young Adults (18)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 18 of 18 Research Studies DisplayedBushnell GA, Rynn MA, Crystal S
Simultaneous benzodiazepine and SSRI initiation in young people with anxiety disorders.
Researchers investigated how often adolescents and young adults with anxiety disorders simultaneously initiate benzodiazepine (BZD) treatment with selective serotonin reuptake inhibitor (SSRI) treatment and examined whether SSRI treatment duration varies by simultaneous BZD initiation. Using a commercial claims database, they found that 4% of adolescents and 17% of young adults simultaneously initiated BZD treatment, varying by age, anxiety disorder, comorbidities, health care utilization, and provider type. They concluded that simultaneous initiation of both treatments is relatively common in young adults with anxiety disorders and was not associated with longer SSRI persistence.
AHRQ-funded; HS026001.
Citation: Bushnell GA, Rynn MA, Crystal S .
Simultaneous benzodiazepine and SSRI initiation in young people with anxiety disorders.
J Clin Psychiatry 2021 Oct 19;82(6). doi: 10.4088/JCP.20m13863..
Keywords: Anxiety, Behavioral Health, Medication, Practice Patterns, Children/Adolescents, Young Adults
Renny MH, Yin HS, Jent V
Temporal trends in opioid prescribing practices in children, adolescents, and younger adults in the US from 2006 to 2018.
Prescription opioids are involved in more than half of opioid overdoses among younger persons. Understanding opioid prescribing practices is essential for developing appropriate interventions for this population. The objective of this study was to examine temporal trends in opioid prescribing practices in children, adolescents, and younger adults in the US from 2006 to 2018.
AHRQ-funded; HS026120.
Citation: Renny MH, Yin HS, Jent V .
Temporal trends in opioid prescribing practices in children, adolescents, and younger adults in the US from 2006 to 2018.
JAMA Pediatr 2021 Oct;175(10):1043-52. doi: 10.1001/jamapediatrics.2021.1832..
Keywords: Children/Adolescents, Young Adults, Opioids, Practice Patterns, Medication
Glenn BA, Nonzee NJ, Tieu L
Human papillomavirus (HPV) vaccination in the transition between adolescence and adulthood.
This study looked at the barriers to human papillomavirus (HPV) vaccination among young adults receiving care at the student health center of a large public university. The authors conducted semi-structured interviews (n=27) and four focus groups with undergraduate and graduate students (n=18) and semi-structured interviews with 6 health care providers. The interviews and focus groups explored perceived risk of HPV infection, benefits of the HPV vaccine, and motivations for and barriers to HPV vaccination. Many students cited their parents’ views and recommendations from their medical providers as influential on their decision-making process. Cervical cancer prevention was considered the main benefit of the HPV vaccine and sexual activity was a risk factor for HPV infection. Students often lacked knowledge about the vaccine’s benefit for males. Safety and side effects of the vaccine perceived as new were also cited. Providers’ vaccine recommendations were impacted by health system factors including clinical infrastructure, office visit priorities, and processes for recommending and documentation vaccination. Providers suggested various promotion strategies including improving the timing and messaging of outreach efforts on campus and bolstering clinical infrastructure.
AHRQ-funded; HS000046.
Citation: Glenn BA, Nonzee NJ, Tieu L .
Human papillomavirus (HPV) vaccination in the transition between adolescence and adulthood.
Vaccine 2021 Jun 8;39(25):3435-44. doi: 10.1016/j.vaccine.2021.04.019..
Keywords: Young Adults, Sexual Health, Infectious Diseases, Vaccination, Prevention, Cancer: Cervical Cancer, Cancer, Women
Heneghan MB, Hussain T, Barrera L
Access to technology and preferences for an mHealth intervention to promote medication adherence in pediatric acute lymphoblastic leukemia: approach leveraging behavior change techniques.
This study’s objectives were to examine access to mobile technology and preferences for an mHealth intervention to improve medication adherence in pediatric acute lymphoblastic leukemia (ALL). Parents of children with ALL as well as adolescents and young adults (AYAs) with ALL who received maintenance chemotherapy were given a cross-sectional survey. Findings showed that parents, adolescents, and AYAs reported ubiquitous access to mobile technology and strong interest in multiple adherence-specific mHealth app features. Parents and AYAs provided valuable insight into preferred features for a multifunctional behavioral intervention to promote medication adherence in pediatric ALL.
AHRQ-funded; HS023011.
Citation: Heneghan MB, Hussain T, Barrera L .
Access to technology and preferences for an mHealth intervention to promote medication adherence in pediatric acute lymphoblastic leukemia: approach leveraging behavior change techniques.
J Med Internet Res 2021 Feb 18;23(2):e24893. doi: 10.2196/24893..
Keywords: Children/Adolescents, Young Adults, Caregiving, Cancer, Medication, Patient Adherence/Compliance, Health Information Technology (HIT), Treatments
Jackman KP, Hightow-Weidman L, Poteat T
Evaluating psychometric determinants of willingness to adopt sexual health patient portal services among black college students: a mixed-methods approach.
The authors used mixed methods to describe perceptions of access to sexually transmitted infection test results via electronic personal health record (PHR) and correlates of willingness to adopt its use. Three qualitative themes emerged on relative advantages, barriers, and functionality of PHRs. Reliable latent factors, centering on PHR convenience and functionality, were positively associated with adoption willingness. Adoption may be boosted with tailored designs responsive to expressed service needs.
AHRQ-funded; HS023057.
Citation: Jackman KP, Hightow-Weidman L, Poteat T .
Evaluating psychometric determinants of willingness to adopt sexual health patient portal services among black college students: a mixed-methods approach.
J Am Coll Health 2021 Feb-Mar;69(2):190-97. doi: 10.1080/07448481.2019.1660352..
Keywords: Electronic Health Records (EHRs), Health Information Technology (HIT), Racial and Ethnic Minorities, Young Adults, Sexual Health, Disparities, Infectious Diseases
Tremblay ES, Ruiz J, Buccigrosso T
Health care transition in youth with type 1 diabetes and an A1C >9%: qualitative analysis of pre-transition perspectives.
The purpose of this training was to explore expectations for transition to adult care and experiences with transition planning among adolescents and young adults with type 1 diabetes and an A1C >9% at a tertiary care U.S. pediatric center. The investigators concluded that a lack of transition preparation and anxiety about transition and adult care among youth with type 1 diabetes and elevated A1C.
AHRQ-funded; HS000063.
Citation: Tremblay ES, Ruiz J, Buccigrosso T .
Health care transition in youth with type 1 diabetes and an A1C >9%: qualitative analysis of pre-transition perspectives.
Diabetes Spectr 2020 Nov;33(4):331-38. doi: 10.2337/ds20-0011..
Keywords: Children/Adolescents, Young Adults, Diabetes, Chronic Conditions, Transitions of Care, Patient Experience
Mills J, Wonoprabowo L
AHRQ Author: Mills J
Primary care-based interventions to prevent illicit drug use in children, adolescents, and young adults.
This case study concerns a 14-year-old patient who presents for a well-child visit. The patient eats a healthy diet, is part of a local soccer league, is an overall good student, and just started high school in the fall. The patient denies trying any illicit substances but reports trying to “get high” from cough syrup. Three questions are presented, and answers provided.
AHRQ-authored.
Citation: Mills J, Wonoprabowo L .
Primary care-based interventions to prevent illicit drug use in children, adolescents, and young adults.
Am Fam Physician 2020 Oct 15;102(8):493-94..
Keywords: Children/Adolescents, Young Adults, Substance Abuse, Primary Care, Prevention, U.S. Preventive Services Task Force (USPSTF), Case Study, Guidelines, Evidence-Based Practice
Cha P, Brindis CD
Early Affordable Care Act Medicaid: coverage effects for low- and moderate-income young adults.
This study examined the effects of early Medicaid expansions on low- and moderate-income young adults. They used the American Community Survey 2008-2013 to study three early expansion states: California, Connecticut and Minnesota. Results shows that Medicaid expansion reduced uninsurance in all three states and increased public insurance in California and Minnesota. Young men benefitted more than young women, who historically tend to be uninsured.
AHRQ-funded; HS022241.
Citation: Cha P, Brindis CD .
Early Affordable Care Act Medicaid: coverage effects for low- and moderate-income young adults.
J Adolesc Health 2020 Sep;67(3):425-31. doi: 10.1016/j.jadohealth.2020.05.029..
Keywords: Young Adults, Policy, Medicaid, Uninsured, Access to Care
Jackman KP, Murray S, Hightow-Weidman
Digital technology to address HIV and other sexually transmitted infection disparities: intentions to disclose online personal health records to sex partners among students at a historically Black college.
Among an online survey sample of co-ed students, the authors described latent constructs and other variables associated with perceived behavioral intentions to disclose sexually transmitted infection (STI) test history using patient portals. They found that latent constructs representing communication valuation beliefs and practices were not associated with intentions, while self-reporting prior STI diagnosis was associated with intentions to disclose. They concluded that point-of-care messages focused on improvements to validating test results, communication, and empowerment, may be an effective strategy to support the adoption of patient portals for STI prevention among populations of college-aged Black youth.
AHRQ-funded; HS023057.
Citation: Jackman KP, Murray S, Hightow-Weidman .
Digital technology to address HIV and other sexually transmitted infection disparities: intentions to disclose online personal health records to sex partners among students at a historically Black college.
PLoS One 2020 Aug 21;15(8):e0237648. doi: 10.1371/journal.pone.0237648..
Keywords: Human Immunodeficiency Virus (HIV), Infectious Diseases, Electronic Health Records (EHRs), Health Information Technology (HIT), Young Adults, Racial and Ethnic Minorities, Prevention
Greenzang KA, Fasciano KM, Block SD
Early information needs of adolescents and young adults about late effects of cancer treatment.
This study evaluated the importance, quality, and implications of information about late effects in adolescents and young adults (AYA) recently diagnosed with cancer. Surveying AYAs with cancer who were 15 to 29 years old and were treated at the Dana-Farber Cancer Institute, researchers found that most AYAs with cancer value early information about the risks of late effects and infertility, yet many patients felt that they had not received high-quality information about these topics. They recommended the development of age-appropriate late-effect communication strategies that recognize high AYA distress to address the gap between desired information and perceived information quality.
AHRQ-funded; HS022986.
Citation: Greenzang KA, Fasciano KM, Block SD .
Early information needs of adolescents and young adults about late effects of cancer treatment.
Cancer 2020 Jul 15;126(14):3281-88. doi: 10.1002/cncr.32932..
Keywords: Children/Adolescents, Young Adults, Cancer, Education: Patient and Caregiver, Clinician-Patient Communication, Communication, Risk
Bushnell GA, Gerhard T, Crystal S
Benzodiazepine treatment and fracture risk in young persons with anxiety disorders.
This study examined whether benzodiazepine treatment increases fall and fracture risk in young persons as it has been shown to do in older adults. They examined whether children (6-17 years) and young adults (18-24) recently diagnosed with anxiety disorder had an increased fracture risk. A cohort of commercially insured children and young adults who had initiated use of benzodiazepine or SSRIs were followed for 3 months, or until fracture, treatment discontinuation or switching or disenrollment occurred. The cohort consisted of 120,715 children and 179,768 young adults. There was an increased fracture rate found in children, but not young adults.
AHRQ-funded; HS026001.
Citation: Bushnell GA, Gerhard T, Crystal S .
Benzodiazepine treatment and fracture risk in young persons with anxiety disorders.
Pediatrics 2020 Jul;146(1):e20193478. doi: 10.1542/peds.2019-3478..
Keywords: Children/Adolescents, Young Adults, Medication, Falls, Injuries and Wounds, Risk, Anxiety, Behavioral Health
Friedman AS, Xu S
Associations of flavored e-cigarette uptake with subsequent smoking initiation and cessation.
Researchers evaluated whether new uptake of flavored e-cigarettes is more strongly associated with subsequent smoking initiation and cessation than uptake of unflavored e-cigarettes for youths, emerging adults, and prime-age adults. The cohort study conducted secondary data analyses of survey data from the Population Assessment of Tobacco and Health Study. The researchers found that vaping uptake was positively associated with smoking initiation in youth and in emerging adults, while vaping uptake was associated with cessation in adults. Additionally, vaping nontobacco flavors was no more associated with youth smoking initiation than vaping tobacco-flavors but was associated with increased adult smoking cessation. They recommended more research to establish the relationship between e-cigarette flavors and smoking and to guide related policy.
AHRQ-funded; HS017589.
Citation: Friedman AS, Xu S .
Associations of flavored e-cigarette uptake with subsequent smoking initiation and cessation.
JAMA Netw Open 2020 Jun;3(6):e203826. doi: 10.1001/jamanetworkopen.2020.3826..
Keywords: Children/Adolescents, Young Adults, Tobacco Use: Smoking Cessation, Tobacco Use, Substance Abuse
Hill LM, Maseko B, Chagomerana M
HIV risk, risk perception, and PrEP interest among adolescent girls and young women in Lilongwe, Malawi: operationalizing the PrEP cascade.
The objective of this study was to understand the level of interest in oral pre-exposure prophylaxis (PrEP) among adolescent girls and young women (AGYW) at highest HIV risk and the potential role of perceived risk in motivating PrEP interest. Findings highlighted key relationships between epidemiologic HIV risk, risk perception, and interest in PrEP. The high number of participants with risk scores below the high-risk cutoff who both expressed high perceived risk and interest in PrEP suggested that the demand for PrEP among AGYW may not be well-aligned with epidemiologic risk.
AHRQ-funded; HS000032.
Citation: Hill LM, Maseko B, Chagomerana M .
HIV risk, risk perception, and PrEP interest among adolescent girls and young women in Lilongwe, Malawi: operationalizing the PrEP cascade.
J Int AIDS Soc 2020 Jun;23 Suppl 3:e25502. doi: 10.1002/jia2.25502..
Keywords: Human Immunodeficiency Virus (HIV), Risk, Prevention, Women, Children/Adolescents, Young Adults
O'Connor E, Thomas R, Senger CA
Interventions to prevent illicit and nonmedical drug use in children, adolescents, and young adults: updated evidence report and systematic review for the US Preventive Services Task Force.
The authors reviewed the benefits and harms of interventions to prevent illicit and nonmedical drug use in children, adolescents, and young adults to inform the US Preventive Services Task Force. They found that the evidence for behavioral counseling interventions to prevent initiation of illicit and nonmedical drug use among adolescents and young adults was inconsistent and imprecise, with some interventions associated with reduction in use and others associated with no benefit or increased use. Health, social, and legal outcomes were sparsely reported, and few showed improvements.
AHRQ-funded; 2902015000017I.
Citation: O'Connor E, Thomas R, Senger CA .
Interventions to prevent illicit and nonmedical drug use in children, adolescents, and young adults: updated evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2020 May 26;323(20):2067-79. doi: 10.1001/jama.2020.1432..
Keywords: U.S. Preventive Services Task Force (USPSTF), Children/Adolescents, Young Adults, Substance Abuse, Primary Care, Prevention, Guidelines, Evidence-Based Practice
Oates GR, Juarez LD, Hansen B
Social risk factors for medication nonadherence: findings from the CARDIA study.
The purpose of this study was to investigate the combined effect of social risk factors on medication nonadherence. Using data from the Coronary Artery Risk Development in Young Adults study, the results showed that low income and chronic stress are associated with medication nonadherence, and that the odds of nonadherence increase with the accumulation of social risk factors. These findings may assist with developing risk prediction tools to identify individuals who can benefit from adherence-promoting interventions.
AHRQ-funded; HS023009.
Citation: Oates GR, Juarez LD, Hansen B .
Social risk factors for medication nonadherence: findings from the CARDIA study.
Am J Health Behav 2020 Mar 1;44(2):232-43. doi: 10.5993/ajhb.44.2.10..
Keywords: Patient Adherence/Compliance, Medication, Risk, Young Adults, Cardiovascular Conditions, Patient-Centered Outcomes Research
Hernandez-Boussard T, Burns CS, Wang NE
The Affordable Care Act reduces emergency department use by young adults: evidence from three States.
The authors tested the impact of the Affordable Care Act (ACA) on how young adults used ED services. They found that the largest relative decreases were found in women and blacks. This relative decrease in ED use implies a total reduction of more than 60,000 visits from young adults across three states in 2011.
AHRQ-funded; HS018558.
Citation: Hernandez-Boussard T, Burns CS, Wang NE .
The Affordable Care Act reduces emergency department use by young adults: evidence from three States.
Health Aff 2014 Sep;33(9):1648-54. doi: 10.1377/hlthaff.2014.0103.
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Keywords: Emergency Department, Health Insurance, Policy, Healthcare Cost and Utilization Project (HCUP), Young Adults
Saloner B, Le Cook B
An ACA provision increased treatment for young adults with possible mental illnesses relative to comparison group.
The researchers examined the impact of the ACA dependent coverage provision on people ages 18-25 with possible mental health or substance use disorders. They found that after implementation of the ACA provision, among people ages 18-25 with possible mental health disorders, mental health treatment increased by 5.3 percentage points relative to a comparison group of similar people ages 26-35. For those using mental health treatment, uninsured visits declined by 12.4 percentage points, and visits paid by private insurance increased by 12.9 percentage points.
AHRQ-funded; HS021486.
Citation: Saloner B, Le Cook B .
An ACA provision increased treatment for young adults with possible mental illnesses relative to comparison group.
Health Aff 2014 Aug;33(8):1425-34. doi: 10.1377/hlthaff.2014.0214.
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Keywords: Access to Care, Health Insurance, Behavioral Health, Substance Abuse, Young Adults
Forehand RL, Williamson RS, Russo GS
College health as a partner in the care of pediatric cancer survivors.
The authors reviewed an initiative to educate providers on pediatric cancer survivor care and to establish a cancer survivor registry in a college health center. They concluded that, through education and optimization of health informatics, college health centers can identify and provide survivor care to this medically vulnerable population.
AHRQ-funded; HS021251.
Citation: Forehand RL, Williamson RS, Russo GS .
College health as a partner in the care of pediatric cancer survivors.
J Am Coll Health 2014;62(7):506-10. doi: 10.1080/07448481.2014.917655.
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Keywords: Cancer, Health Services Research (HSR), Young Adults, Education: Academic