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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 6 of 6 Research Studies DisplayedConnolly Gibbons MB, Gallop R, Thompson D
Comparative effectiveness of cognitive therapy and dynamic psychotherapy for major depressive disorder in a community mental health setting: a randomized clinical noninferiority trial.
The authors sought to determine whether dynamic psychotherapy (DT) is not inferior to cognitive therapy (CT) in the treatment of major depressive disorder (MDD) in a community mental health setting. This study suggests that DT is not inferior to CT on change in depression for the treatment of MDD in a community mental health setting.
AHRQ-funded; HS018440.
Citation: Connolly Gibbons MB, Gallop R, Thompson D .
Comparative effectiveness of cognitive therapy and dynamic psychotherapy for major depressive disorder in a community mental health setting: a randomized clinical noninferiority trial.
JAMA Psychiatry 2016 Sep;73(9):904-11. doi: 10.1001/jamapsychiatry.2016.1720.
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Keywords: Comparative Effectiveness, Community-Based Practice, Depression, Behavioral Health, Patient-Centered Outcomes Research
Elliot DL, Goldberg L, MacKinnon DP
Empiric validation of a process for behavior change.
In this report, the researchers compared the process of change for three evidence-based programs that shared theories, intervention elements and potential mediating variables. Each investigation assessed pre- and post-intervention variables using survey constructs with established reliability. Each used mediation analyses to define relationships. They found that knowledge was a significant mediator in each program, and that norms, perceived control abilities, and self-monitoring were confirmed in at least two studies. The researchers concluded that combined findings demonstrate a means to substantiate process aspects and theoretical models to advance understanding of behavior change.
AHRQ-funded; HS022981; HS019456.
Citation: Elliot DL, Goldberg L, MacKinnon DP .
Empiric validation of a process for behavior change.
Transl Behav Med 2016 Sep;6(3):449-56. doi: 10.1007/s13142-015-0343-y.
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Keywords: Behavioral Health, Comparative Effectiveness, Patient-Centered Outcomes Research
Smith LR, Earnshaw VA, Copenhaver MM
Substance use stigma: reliability and validity of a theory-based scale for substance-using populations.
The researchers aimed to advance measurement efforts of substance use stigma by drawing on stigma theory to develop and evaluate the Substance Use Stigma Mechanisms Scale (SU-SMS). Their findings support the structural and construct validity of the SU-SMS, suggesting the scale was able to capture enacted, anticipated, and internalized stigma as distinct stigma experiences, also differentiating between two distinct stigma sources, family and healthcare providers. They concluded that the SU-SMS may serve as a valuable tool for better understanding the processes through which substance use stigma serves to undermine key health behaviors and outcomes among persons with substance use disorders.
AHRQ-funded; HS022986.
Citation: Smith LR, Earnshaw VA, Copenhaver MM .
Substance use stigma: reliability and validity of a theory-based scale for substance-using populations.
Drug Alcohol Depend 2016 May 1;162:34-43. doi: 10.1016/j.drugalcdep.2016.02.019.
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Keywords: Behavioral Health, Patient-Centered Outcomes Research, Social Stigma, Substance Abuse
Lin LY, Sidani JE, Shensa A
Association between social media use and depression among U.S. young adults.
The authors assessed the association between social media use and depression in a nationally representative sample of young adults. They found that participants in the highest quartile of total time per day using social media had significantly increased odds of depression. They conluded that social media use was significantly associated with increased depression.
AHRQ-funded; HS022989.
Citation: Lin LY, Sidani JE, Shensa A .
Association between social media use and depression among U.S. young adults.
Depress Anxiety 2016 Apr;33(4):323-31. doi: 10.1002/da.22466.
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Keywords: Social Media, Depression, Young Adults, Behavioral Health, Patient-Centered Outcomes Research
Deckersbach T, Nierenberg AA, McInnis MG
Baseline disability and poor functioning in bipolar disorder predict worse outcomes: results from the Bipolar CHOICE study.
This study examined the effects of treatment on functioning impairments and quality of life and assessed baseline functioning and employment status as predictors of treatment response in symptomatic individuals from the Bipolar Clinical Health Outcomes Initiative in Comparative Effectiveness (Bipolar CHOICE) study. It found that prior disability status was associated with a worse treatment response and prospective illness course.
AHRQ-funded; HS019371.
Citation: Deckersbach T, Nierenberg AA, McInnis MG .
Baseline disability and poor functioning in bipolar disorder predict worse outcomes: results from the Bipolar CHOICE study.
J Clin Psychiatry 2016 Jan;77(1):100-8. doi: 10.4088/JCP.14m09210.
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Keywords: Behavioral Health, Comparative Effectiveness, Patient-Centered Outcomes Research, Medication
Nierenberg AA, McElroy SL, Friedman ES
Bipolar CHOICE (Clinical Health Outcomes Initiative in Comparative Effectiveness): a pragmatic 6-month trial of lithium versus quetiapine for bipolar disorder.
The purpose of this trial was to compare lithium and second-generation antipsychotics. The investigators found that outcomes with lithium + APT and quetiapine + APT were not significantly different across 6 months of treatment for bipolar disorder.
AHRQ-funded; HS019371.
Citation: Nierenberg AA, McElroy SL, Friedman ES .
Bipolar CHOICE (Clinical Health Outcomes Initiative in Comparative Effectiveness): a pragmatic 6-month trial of lithium versus quetiapine for bipolar disorder.
J Clin Psychiatry 2016 Jan;77(1):90-9. doi: 10.4088/JCP.14m09349.
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Keywords: Adverse Drug Events (ADE), Comparative Effectiveness, Medication, Behavioral Health, Patient-Centered Outcomes Research