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AHRQ Research Studies Date
Topics
- Cardiovascular Conditions (2)
- Care Management (1)
- Chronic Conditions (1)
- Comparative Effectiveness (1)
- Depression (1)
- (-) Diabetes (9)
- Elderly (1)
- Lifestyle Changes (1)
- Low-Income (1)
- Medication (2)
- Nutrition (1)
- Obesity (2)
- Obesity: Weight Management (2)
- Outcomes (2)
- (-) Patient-Centered Outcomes Research (9)
- Patient Adherence/Compliance (2)
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 9 of 9 Research Studies DisplayedFlory JH, Ukena JK, Floyd JS
Novel anti-glycemic drugs and reduction of cardiovascular risk in diabetes: expectations realized, promises unmet.
The researchers review evidence on cardiovascular risks and benefits of new treatments for type 2 diabetes mellitus. Their review reports new evidence suggesting that the newest diabetes drugs are safe from a cardiovascular perspective. Evidence on benefit from at least some members of the GLP-1 receptor agonist and SGLT-2 inhibitor classes is encouraging but not yet decisive.
AHRQ-funded; HS023898.
Citation: Flory JH, Ukena JK, Floyd JS .
Novel anti-glycemic drugs and reduction of cardiovascular risk in diabetes: expectations realized, promises unmet.
Curr Atheroscler Rep 2016 Dec;18(12):79. doi: 10.1007/s11883-016-0633-y.
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Keywords: Patient-Centered Outcomes Research, Medication, Diabetes, Cardiovascular Conditions, Risk
Patil SJ, Ruppar T, Koopman RJ
Peer support interventions for adults with diabetes: a meta-analysis of hemoglobin A1c outcomes.
This study aimed to estimate the effect of peer support interventions delivered by people affected by diabetes (those with the disease or a caregiver) on hemoglobin A1c (HbA1c) levels in adults. It found that peer support interventions for diabetes overall achieved a statistically significant but minor improvement in HbA1c levels.
AHRQ-funded; HS022140.
Citation: Patil SJ, Ruppar T, Koopman RJ .
Peer support interventions for adults with diabetes: a meta-analysis of hemoglobin A1c outcomes.
Ann Fam Med 2016 Nov;14(6):540-51. doi: 10.1370/afm.1982.
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Keywords: Care Management, Diabetes, Patient-Centered Outcomes Research
Fischer HH, Fischer IP, Pereira RI
Text message support for weight loss in patients with prediabetes: a randomized clinical trial.
This study explores whether text message support enhances weight loss in patients offered Diabetes Prevention Program (DPP) classes. Stratification by language demonstrated a significant treatment effect in Spanish speakers but not in English speakers. It concluded that text message support can lead to clinically significant weight loss in patients with prediabetes.
AHRQ-funded; HS022143.
Citation: Fischer HH, Fischer IP, Pereira RI .
Text message support for weight loss in patients with prediabetes: a randomized clinical trial.
Diabetes Care 2016 Aug;39(8):1364-70. doi: 10.2337/dc15-2137.
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Keywords: Diabetes, Obesity, Patient-Centered Outcomes Research, Social Media, Obesity: Weight Management
Huang ES
Management of diabetes mellitus in older people with comorbidities.
Guidelines recommend that physicians individualize the intensity of glucose control and treatments on the basis of the prognosis (for example, three tiers based on comorbidities and functional impairments). Very few studies have attempted to study these concepts in clinical practice. To better meet the treatment needs of older patients with diabetes and comorbidities, more research is needed to determine the risks and benefits of intensifying, maintaining, or de-intensifying treatments in this population.
AHRQ-funded; HS018542.
Citation: Huang ES .
Management of diabetes mellitus in older people with comorbidities.
BMJ 2016 Jun 15;353:i2200. doi: 10.1136/bmj.i2200.
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Keywords: Diabetes, Elderly, Patient-Centered Outcomes Research, Chronic Conditions
Heerman WJ, Wallston KA, Osborn CY
Food insecurity is associated with diabetes self-care behaviours and glycaemic control.
The objective of the study was to examine the association between food insecurity, diabetes self-care and glycaemic control. It concluded that there was a high rate of food insecurity in a sample of patients with Type 2 diabetes who were of low socio-economic status. Food insecurity was associated with less adherence to recommended self-care behaviours and worse glycaemic control.
AHRQ-funded; HS022990.
Citation: Heerman WJ, Wallston KA, Osborn CY .
Food insecurity is associated with diabetes self-care behaviours and glycaemic control.
Diabet Med 2016 Jun;33(6):844-50. doi: 10.1111/dme.12896.
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Keywords: Diabetes, Nutrition, Patient Adherence/Compliance, Patient-Centered Outcomes Research, Patient Self-Management
Osborn CY, Mayberry LS, Kim JM
Medication adherence may be more important than other behaviours for optimizing glycaemic control among low-income adults.
The authors sought to identify which behaviors are most important for HbA1c among low-socioeconomic status patients with type 2 diabetes mellitus. They found that only medication adherence was significantly associated with lower HbA1c after adjusting for the other self-care behaviours and further adjusting for demographic and diabetes characteristics. They suggested that focused efforts to improve medication adherence among low-socioeconomic status patient populations may improve glycemic control.
AHRQ-funded; HS022990.
Citation: Osborn CY, Mayberry LS, Kim JM .
Medication adherence may be more important than other behaviours for optimizing glycaemic control among low-income adults.
J Clin Pharm Ther 2016 Jun;41(3):256-9. doi: 10.1111/jcpt.12360.
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Keywords: Diabetes, Low-Income, Medication, Patient Adherence/Compliance, Patient-Centered Outcomes Research
Ehrlich SF, Sternfeld B, Krefman AE
Moderate and vigorous intensity exercise during pregnancy and gestational weight gain in women with gestational diabetes.
The researchers estimated the associations of exercise intensity during pregnancy with the rate of gestational weight gain (GWG) from gestational diabetes (GDM) diagnosis to delivery. Upon stratification by prepregnancy overweight/obesity, they found that significant associations were only observed for BMI greater than or equal to 25.0. There were no associations observed for moderate intensity exercise.
AHRQ-funded; HS019367.
Citation: Ehrlich SF, Sternfeld B, Krefman AE .
Moderate and vigorous intensity exercise during pregnancy and gestational weight gain in women with gestational diabetes.
Matern Child Health J 2016 Jun;20(6):1247-57. doi: 10.1007/s10995-016-1926-z.
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Keywords: Diabetes, Lifestyle Changes, Obesity, Obesity: Weight Management, Outcomes, Patient-Centered Outcomes Research, Pregnancy, Women
Cummings DM, Kirian K, Howard G
Consequences of comorbidity of elevated stress and/or depressive symptoms and incident cardiovascular outcomes in diabetes: results from the REasons for Geographic And Racial Differences in Stroke (REGARDS) study.
The authors evaluated the impact of comorbid depressive symptoms and/or stress on adverse cardiovascular (CV) outcomes in individuals with diabetes compared with those without diabetes. They concluded that comorbid stress and/or depressive symptoms are common in individuals with diabetes and together are associated with progressively increased risks for adverse CV outcomes.
AHRQ-funded; HS023009.
Citation: Cummings DM, Kirian K, Howard G .
Consequences of comorbidity of elevated stress and/or depressive symptoms and incident cardiovascular outcomes in diabetes: results from the REasons for Geographic And Racial Differences in Stroke (REGARDS) study.
Diabetes Care 2016 Jan;39(1):101-9. doi: 10.2337/dc15-1174.
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Keywords: Cardiovascular Conditions, Depression, Diabetes, Patient-Centered Outcomes Research, Stress
Neugebauer R, Fireman B, Roy JA
Impact of specific glucose-control strategies on microvascular and macrovascular outcomes in 58,000 adults with type 2 diabetes.
This study used comparative effectiveness research methods to compare the effect of four distinct glucose-control strategies on subsequent myocardial infarction and nephropathy in type 2 diabetes. It found that in a large group of adults with type 2 diabetes, more aggressive glucose-control strategies have mixed short-term effects on microvascular complications and do not reduce the myocardial infarction rate over 4 years of follow-up.
AHRQ-funded; 29020050033I.
Citation: Neugebauer R, Fireman B, Roy JA .
Impact of specific glucose-control strategies on microvascular and macrovascular outcomes in 58,000 adults with type 2 diabetes.
Diabetes Care 2013 Nov;36(11):3510-6. doi: 10.2337/dc12-2675..
Keywords: Comparative Effectiveness, Diabetes, Outcomes, Patient-Centered Outcomes Research, Treatments