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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 2 of 2 Research Studies DisplayedTotten M, Ross T, Voskertchian A
Analysis of morphologically similar Staphylococcus aureus colonies for assessment of phenotypic and genotypic correlation.
In an effort to track and control the transmission of Staphylococcus aureus, patient isolates are saved for epidemiological studies (1–3). Study investigators often assume that colonies with the same morphology on the original culture plate represent the same clone. However, there is very limited literature to support this assumption. In this study, multiple S. aureus colonies were saved from a single culture plate and tested to determine their genotypes and susceptibility profiles.
AHRQ-funded; HS022872.
Citation: Totten M, Ross T, Voskertchian A .
Analysis of morphologically similar Staphylococcus aureus colonies for assessment of phenotypic and genotypic correlation.
J Clin Microbiol 2017 Jul;55(7):2285-86. doi: 10.1128/jcm.00402-17..
Keywords: Genetics, Infectious Diseases, Research Methodologies
Rodriguez M, Hogan PG, Satola SW
Discriminatory indices of typing methods for epidemiologic analysis of contemporary Staphylococcus aureus strains.
The researchers compared the discriminatory index of 5 typing methods for contemporary S. aureus strain characterization. They found that the typing methods yielded comparable discriminatory power for Aureus characterization overall; when discriminating among USA300 isolates, repetitive sequence-based PCR (repPCR) retained the highest discriminatory power.
AHRQ-funded; HS021736.
Citation: Rodriguez M, Hogan PG, Satola SW .
Discriminatory indices of typing methods for epidemiologic analysis of contemporary Staphylococcus aureus strains.
Medicine 2015 Sep;94(37):e1534. doi: 10.1097/md.0000000000001534..
Keywords: Research Methodologies, Genetics, Public Health