National Healthcare Quality and Disparities Report
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 3 of 3 Research Studies DisplayedMcCarthy IM
Putting the patient in patient reported outcomes: a robust methodology for health outcomes assessment.
Through a series of Monte Carlo simulations, this paper illustrates that reliance solely on the summary score may lead to biased estimates of incremental effects, and proposes a novel two-stage approach that allows for unbiased estimation of incremental effects. The proposed methodology essentially reverses the order of the analysis, from one of 'aggregate, then estimate' to one of 'estimate, then aggregate'.
AHRQ-funded; HS022431.
Citation: McCarthy IM .
Putting the patient in patient reported outcomes: a robust methodology for health outcomes assessment.
Health Econ 2015 Dec;24(12):1588-603. doi: 10.1002/hec.3113.
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Keywords: Patient-Centered Outcomes Research, Outcomes, Quality of Life, Research Methodologies
Dusetzina SB, Brookhart MA, Maciejewski ML
Control outcomes and exposures for improving internal validity of nonrandomized studies.
The authors review examples of control outcomes and exposures from prior studies and provide recommendations for conducting and reporting these analyses. They found that there is inconsistent terminology for these concepts, making study identification challenging. They recommend that the rigor of nonrandomized studies can be improved with inclusion of control outcomes and exposures for bias detection.
AHRQ-funded; HS023099; HS023085.
Citation: Dusetzina SB, Brookhart MA, Maciejewski ML .
Control outcomes and exposures for improving internal validity of nonrandomized studies.
Health Serv Res 2015 Oct;50(5):1432-51. doi: 10.1111/1475-6773.12279..
Keywords: Research Methodologies, Patient-Centered Outcomes Research, Outcomes
Smith SR
AHRQ Author: Smith SR
Preface to the AHRQ supplement.
AHRQ, through its Developing Evidence to Inform Decisions about Effectiveness (DEcIDE) Research Network, sponsored this supplement to present various strategies in the design, analysis, and conduct of health outcomes studies relevant to rare diseases. The purpose of this supplement is to disseminate illustrative examples of research methods that can be applied to understand health outcomes and potentially to stimulate new patient-centered outcomes studies for rare diseases.
AHRQ-authored.
Citation: Smith SR .
Preface to the AHRQ supplement.
J Gen Intern Med 2014 Aug;29 Suppl 3:S712-3. doi: 10.1007/s11606-014-2922-x.
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Keywords: Comparative Effectiveness, Evidence-Based Practice, Outcomes, Patient-Centered Outcomes Research, Research Methodologies