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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 5 of 5 Research Studies DisplayedDownes KJ, Patil NR, Rao MB
Risk factors for acute kidney injury during aminoglycoside therapy in patients with cystic fibrosis.
The aim of this study was to identify factors associated with acute kidney injury (AKI) during intravenous aminoglycoside (AG) courses in this population. It identified receipt of an AG within 90 days prior to admission, longer duration of AG therapy, low serum albumin, and receipt of trimethoprim/ sulfamethoxazole as independent risk factors for developing AKI.
AHRQ-funded; HS021114.
Citation: Downes KJ, Patil NR, Rao MB .
Risk factors for acute kidney injury during aminoglycoside therapy in patients with cystic fibrosis.
Pediatr Nephrol 2015 Oct;30(10):1879-88. doi: 10.1007/s00467-015-3097-3..
Keywords: Adverse Events, Patient-Centered Outcomes Research, Patient Safety, Respiratory Conditions
Michelson KA, Monuteaux MC, Neuman MI
Glucocorticoids and hospital length of stay for children with anaphylaxis: a retrospective study.
The objective of this study was to evaluate whether glucocorticoid administration is associated with improved outcomes in children with anaphylaxis. The investigators found that the use of glucocorticoids was inversely associated with prolonged length of stay among children hospitalized with anaphylaxis, but was not associated with 3-day emergency department revisits among discharged children, thus supporting the use of glucocorticoids in children hospitalized with anaphylaxis.
AHRQ-funded; HS000063.
Citation: Michelson KA, Monuteaux MC, Neuman MI .
Glucocorticoids and hospital length of stay for children with anaphylaxis: a retrospective study.
J Pediatr 2015 Sep;167(3):719-24.e1-3. doi: 10.1016/j.jpeds.2015.05.033.
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Keywords: Children/Adolescents, Medication, Respiratory Conditions, Respiratory Conditions, Patient-Centered Outcomes Research
Wysham NG, Cox CE, Wolf SP
Symptom burden of chronic lung disease compared with lung cancer at time of referral for palliative care consultation.
The authors compared the symptom burden of chronic lung disease with that of lung cancer at the time of initial palliative care consultation. They found that patients with chronic lung disease have symptom burdens similar to those of patients with lung cancer at the time of the first palliative care encounter. They concluded that, given the population burden of chronic lung disease and limitations in the palliative care workforce, attention should be focused on ensuring that pulmonologists are prepared to assess and manage the common palliative care needs of patients with chronic lung disease.
AHRQ-funded; HS023681.
Citation: Wysham NG, Cox CE, Wolf SP .
Symptom burden of chronic lung disease compared with lung cancer at time of referral for palliative care consultation.
Ann Am Thorac Soc 2015 Sep;12(9):1294-301. doi: 10.1513/AnnalsATS.201503-180OC.
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Keywords: Respiratory Conditions, Cancer: Lung Cancer, Pain, Palliative Care, Patient-Centered Outcomes Research
Hajizadeh N, Goldfeld
What happens to patients with COPD with long-term oxygen treatment who receive mechanical ventilation for COPD exacerbation? A 1-year retrospective follow-up study.
This study describes outcomes for patients with chronic obstructive pulmonary disease (COPD) on long-term oxygen treatment who are admitted to an ICU for respiratory failure and receive invasive mechanical ventilation. Of the 4,791 patients, 23 percent died in the hospital, and 45 percent died in the subsequent 12 months. Also, 67 percent of patients were readmitted at least once in the subsequent 12 months.
AHRQ-funded; HS019473.
Citation: Hajizadeh N, Goldfeld .
What happens to patients with COPD with long-term oxygen treatment who receive mechanical ventilation for COPD exacerbation? A 1-year retrospective follow-up study.
Thorax 2015 Mar;70(3):294-6. doi: 10.1136/thoraxjnl-2014-205248..
Keywords: Patient-Centered Outcomes Research, Outcomes, Comparative Effectiveness, Respiratory Conditions
Kaplan RM, Sun Q, Ries AL
AHRQ Author: Kaplan RM
Quality of well-being outcomes in the National Emphysema Treatment Trial.
The purpose of this article is to report outcomes from the National Emphysema Treatment Trial (NETT) using an index that combines quality and quantity of life. Results showed that, compared with maximal medical therapy alone, patients undergoing maximal medical therapy plus lung volume reduction surgery experienced improved health-related quality of life and gained more quality-adjusted life years.
AHRQ-authored.
Citation: Kaplan RM, Sun Q, Ries AL .
Quality of well-being outcomes in the National Emphysema Treatment Trial.
Chest 2015 Feb;147(2):377-87. doi: 10.1378/chest.14-0528.
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Keywords: Comparative Effectiveness, Patient-Centered Outcomes Research, Quality of Life, Respiratory Conditions, Surgery