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Search All Research Studies
AHRQ Research Studies Date
Topics
- Asthma (1)
- Cardiovascular Conditions (1)
- Care Management (1)
- Centers for Education and Research on Therapeutics (CERTs) (1)
- (-) Chronic Conditions (9)
- Comparative Effectiveness (2)
- Hepatitis (1)
- Home Healthcare (1)
- Human Immunodeficiency Virus (HIV) (1)
- Medicaid (1)
- Medication (6)
- Patient-Centered Healthcare (2)
- (-) Patient Adherence/Compliance (9)
- Patient Self-Management (1)
- Young Adults (1)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 9 of 9 Research Studies DisplayedLaFleur J, Hoop R, Korner E
Predictors of early discontinuation of pegylated interferon for reasons other than lack of efficacy in United States veterans with chronic hepatitis C.
The researchers determined whether selected patient characteristics predicted discontinued therapy for reasons other than lack of efficcacy (non-LOE) using national databases of U.S. veterans. They found that predictors of greatest magnitude included comorbidities of myocardial infarction/congestive heart failure, renal disease, platelets 100/mm or more, Black race, albumin 3.5 mg/dl or more, sleep aid use, and poor persistence with antidepressants and antihypertensive agents.
AHRQ-funded; HS018582.
Citation: LaFleur J, Hoop R, Korner E .
Predictors of early discontinuation of pegylated interferon for reasons other than lack of efficacy in United States veterans with chronic hepatitis C.
Gastroenterol Nurs 2015 Nov-Dec;38(6):417-28. doi: 10.1097/sga.0000000000000214.
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Keywords: Chronic Conditions, Hepatitis, Medication, Patient Adherence/Compliance
Shah ED, Siegel CA, Chong K
Patients with Crohn's disease are more likely to remain on biologics than immunomodulators: a meta-analysis of treatment durability.
The researchers aimed to clarify treatment durability by assessing subject discontinuations from clinical trials in the context of treatment efficacy. They found that for patients with Crohn’s disease, biologic therapies had higher durability than immunomodulators for induction and maintenance therapy.
AHRQ-funded; HS021747.
Citation: Shah ED, Siegel CA, Chong K .
Patients with Crohn's disease are more likely to remain on biologics than immunomodulators: a meta-analysis of treatment durability.
Dig Dis Sci 2015 Aug;60(8):2408-18. doi: 10.1007/s10620-015-3618-8..
Keywords: Patient Adherence/Compliance, Medication, Chronic Conditions, Comparative Effectiveness
Agwu AL, Lee L, Fleishman JA
AHRQ Author: Fleishman JA
Aging and loss to follow-up among youth living with human immunodeficiency virus in the HIV Research Network.
The researchers sought to evaluate loss to follow-up in the year after each birthday from the 18th through the 25th in a large multisite HIV cohort in the United States. Among the 647 21-year-old youth who were engaged in care, 20 percent were lost to follow-up in the year after their 21st birthday.
AHRQ-authored; AHRQ-funded; 2901100007.
Citation: Agwu AL, Lee L, Fleishman JA .
Aging and loss to follow-up among youth living with human immunodeficiency virus in the HIV Research Network.
J Adolesc Health 2015 Mar;56(3):345-51. doi: 10.1016/j.jadohealth.2014.11.009..
Keywords: Care Management, Chronic Conditions, Human Immunodeficiency Virus (HIV), Patient Adherence/Compliance, Young Adults
Hansen RA, Voils CI, Farley JF
Prescriber continuity and medication adherence for complex patients.
The purpose of this study was to examine the relationship between number of prescribers, number of conditions, and refill adherence to oral medications among 7,933 veterans who were identified with 1 to 4 cardiometabolic conditions: diabetes, hypertension, dyslipidemia, and/or heart failure. It found that for veterans taking antihypertensive or lipid-lowering medications, having more prescribers involved in care modestly decreased the likelihood of being adherent.
AHRQ-funded; HS019445.
Citation: Hansen RA, Voils CI, Farley JF .
Prescriber continuity and medication adherence for complex patients.
Ann Pharmacother 2015 Mar;49(3):293-302. doi: 10.1177/1060028014563266..
Keywords: Patient Adherence/Compliance, Medication, Chronic Conditions
Beadles CA, Farley JF, Ellis AR
Do medical homes increase medication adherence for persons with multiple chronic conditions?
The goal of this study was to assess the association between medical homes and adherence to newly initiated medications among Medicaid enrollees with multiple chronic conditions (MCC). The researchers examined data from North Carolina Medicaid enrollees with MCC and found that adherence to new medications is greater for those enrolled in medical homes.
AHRQ-funded; HS000032; HS019659.
Citation: Beadles CA, Farley JF, Ellis AR .
Do medical homes increase medication adherence for persons with multiple chronic conditions?
Med Care 2015 Feb;53(2):168-76. doi: 10.1097/mlr.0000000000000292..
Keywords: Chronic Conditions, Medication, Medicaid, Patient Adherence/Compliance, Patient-Centered Healthcare
McMullen CK, Safford MM, Bosworth HB
Patient-centered priorities for improving medication management and adherence.
The goal of the workshop was to identify and prioritize opportunities to advance PCMM by convening diverse stakeholders involved in prescribing and/or medication taking. A major conclusion was that engaging multiple stakeholders in setting a patient-centered research agenda and broadening the scope of adherence interventions to include other aspects of medication management resulted in priorities outside the traditional scope of adherence research.
AHRQ-funded; HS021093; HS021094; HS021107.
Citation: McMullen CK, Safford MM, Bosworth HB .
Patient-centered priorities for improving medication management and adherence.
Patient Educ Couns 2015 Jan;98(1):102-10. doi: 10.1016/j.pec.2014.09.015..
Keywords: Centers for Education and Research on Therapeutics (CERTs), Chronic Conditions, Medication, Patient Adherence/Compliance, Patient-Centered Healthcare
Mowrer JL, Tapp H, Ludden T
Patients' and providers' perceptions of asthma and asthma care: a qualitative study.
The primary goal of this qualitative study was to further explore patient and provider perceptions of asthma and asthma care as part of a larger Asthma Comparative Effectiveness Study. Three overarching themes, with a variety of subthemes, emerged as the main findings of this study. The three main themes were Cost/Economic Barriers/Process, Self-Governance/Adherence and Education.
AHRQ-funded; HS019946.
Citation: Mowrer JL, Tapp H, Ludden T .
Patients' and providers' perceptions of asthma and asthma care: a qualitative study.
J Asthma 2015;52(9):949-56. doi: 10.3109/02770903.2015.1010731..
Keywords: Asthma, Comparative Effectiveness, Patient Adherence/Compliance, Chronic Conditions
Kendall L, Eschler J, Lozano P
Engineering for reliability in at-home chronic disease management.
The researchers examined how individuals responsible for managing their own or others’ chronic conditions integrate reminders and notification systems into their daily routines. Based on the participants’ experiences, they contend that many self-management failures should be viewed as systems failures, rather than individual failures and non-compliance.
AHRQ-funded; HS021590.
Citation: Kendall L, Eschler J, Lozano P .
Engineering for reliability in at-home chronic disease management.
AMIA Annu Symp Proc 2014 Nov 14;2014:777-86..
Keywords: Chronic Conditions, Patient Self-Management, Home Healthcare, Patient Adherence/Compliance
Kesselheim AS, Bykov K, Avorn J
Burden of changes in pill appearance for patients receiving generic cardiovascular medications after myocardial infarction: cohort and nested case-control studies.
This study sought to determine whether nonpersistent use of generic drugs among patients with cardiovascular disease after a heart attack is associated with the different shapes or colors of generic medications. It found that patients who subsequently discontinued treatment with their cardiovascular medications were 30 percent more likely to have had a change in pill shape or color preceding the discontinuation.
AHRQ-funded; HS018465
Citation: Kesselheim AS, Bykov K, Avorn J .
Burden of changes in pill appearance for patients receiving generic cardiovascular medications after myocardial infarction: cohort and nested case-control studies.
Ann Intern Med. 2014 Jul 15;161(2):96-103. doi: 10.7326/M13-2381..
Keywords: Cardiovascular Conditions, Medication, Chronic Conditions, Patient Adherence/Compliance