National Healthcare Quality and Disparities Report
Latest available findings on quality of and access to health care
Data
- Data Infographics
- Data Visualizations
- Data Tools
- Data Innovations
- All-Payer Claims Database
- Healthcare Cost and Utilization Project (HCUP)
- Medical Expenditure Panel Survey (MEPS)
- AHRQ Quality Indicator Tools for Data Analytics
- State Snapshots
- United States Health Information Knowledgebase (USHIK)
- Data Sources Available from AHRQ
Search All Research Studies
AHRQ Research Studies Date
Topics
- (-) Cancer (8)
- Cancer: Breast Cancer (1)
- Chronic Conditions (1)
- Comparative Effectiveness (1)
- Data (1)
- Diagnostic Safety and Quality (1)
- Elderly (1)
- Evidence-Based Practice (1)
- Health Status (1)
- Imaging (1)
- Medication (1)
- Patient-Centered Healthcare (2)
- Patient-Centered Outcomes Research (3)
- Quality Indicators (QIs) (1)
- (-) Research Methodologies (8)
AHRQ Research Studies
Sign up: AHRQ Research Studies Email updates
Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 8 of 8 Research Studies DisplayedReimer T, Lee SJC, Garcia S
Cancer center clinic and research team perceptions of identity and interactions.
The purpose of this study was to determine perceptions of roles of cancer center clinic and research teams. The researchers developed and administered survey to research and clinic staff at a National Cancer Institute-designated comprehensive cancer center. Although there are many similarities between clinic and research teams, the researchers also identified key differences, including perceptions of goal clarity and sharing, understanding and alignment with cancer center goals, and importance of outcomes.
AHRQ-funded; HS022418.
Citation: Reimer T, Lee SJC, Garcia S .
Cancer center clinic and research team perceptions of identity and interactions.
J Oncol Pract 2017 Dec;13(12):e1021-e29. doi: 10.1200/jop.2017.024349..
Keywords: Cancer, Patient-Centered Healthcare, Patient-Centered Outcomes Research, Research Methodologies
Pak K, Uno H, Kim DH
Interpretability of cancer clinical trial results using restricted mean survival time as an alternative to the hazard ratio.
To discuss issues of conventional trial design and analysis and to present alternatives to the hazard ratio (HR) using a recent immunotherapy study as an illustrative example. The investigators suggest that the design and analysis of a conventional cancer clinical trial can be improved by adopting a robust statistical procedure that enables clinically meaningful interpretations of the treatment effect.
AHRQ-funded; HS022193.
Citation: Pak K, Uno H, Kim DH .
Interpretability of cancer clinical trial results using restricted mean survival time as an alternative to the hazard ratio.
JAMA Oncol 2017 Dec;3(12):1692-96. doi: 10.1001/jamaoncol.2017.2797..
Keywords: Cancer, Research Methodologies
Kelly G, Wang SY, Lucas G
Facilitating meaningful engagement on community advisory committees in patient-centered outcome research.
In this study, the investigators conducted a process evaluation of ongoing activities of a Patient Advisory Committee (PAC) formed around the development of an individualized decision aid for older women with early stage breast cancer. They indicated that their results suggested that engaging committee members in a process of evaluation and collective reflection during a research collaboration can break down barriers to collaboration, build relationships, create opportunities for co-learning and strengthen researchers' capacity to engage meaningfully with stakeholders.
AHRQ-funded; HS023900.
Citation: Kelly G, Wang SY, Lucas G .
Facilitating meaningful engagement on community advisory committees in patient-centered outcome research.
Prog Community Health Partnersh 2017;11(3):243-51. doi: 10.1353/cpr.2017.0029..
Keywords: Cancer, Cancer: Breast Cancer, Patient-Centered Healthcare, Patient-Centered Outcomes Research, Research Methodologies
Wang WJ, Robertson JC, Basu A
Burden of illness and research investments in translational sciences for pharmaceuticals in metastatic cancers.
This study explored whether investments in translational sciences for six metastatic cancers follow idiosyncratic returns to those investments rather than levels of burden of illness (BI). It concluded that investments in trials were positively associated only with contemporary changes in BI (2008-2014). The relationship was stronger for government-sponsored comparative-effectiveness trials than for industry.
AHRQ-funded; HS022982.
Citation: Wang WJ, Robertson JC, Basu A .
Burden of illness and research investments in translational sciences for pharmaceuticals in metastatic cancers.
J Comp Eff Res 2017 Jan;6(1):15-24. doi: 10.2217/cer-2016-0021.
.
.
Keywords: Cancer, Comparative Effectiveness, Medication, Research Methodologies
Ma X, Chen Y, Cole SR
A hybrid Bayesian hierarchical model combining cohort and case-control studies for meta-analysis of diagnostic tests: accounting for partial verification bias.
In this paper, the authors proposed a novel hybrid Bayesian hierarchical model combining cohort and case-control studies while simultaneously correcting partial verification bias. They presented two case studies on assessing the diagnostic accuracy of gadolinium-enhanced magnetic resonance imaging in detecting lymph node metastases and of adrenal fluorine-18 fluorodeoxyglucose positron emission tomography in characterizing adrenal masses.
AHRQ-funded; HS022900.
Citation: Ma X, Chen Y, Cole SR .
A hybrid Bayesian hierarchical model combining cohort and case-control studies for meta-analysis of diagnostic tests: accounting for partial verification bias.
Stat Methods Med Res 2016 Dec;25(6):3015-37. doi: 10.1177/0962280214536703.
.
.
Keywords: Cancer, Diagnostic Safety and Quality, Imaging, Research Methodologies
Patel HD, Iyoha E, Pierorazio PM
A systematic review of research gaps in the evaluation and management of localized renal masses.
The authors conducted a systematic review to summarize research gaps for the evaluation of composite models for predicting malignancy; use of percutaneous renal sampling for diagnosis; and comparative effectiveness of surgery, thermal ablation, and active surveillance. They recommended incorporation of emerging biomarkers into validated composite models, standardization of biopsy protocols, standard reporting of clinical stage, and performance of prospective studies with objective selection criteria.
AHRQ-funded; 290201200007I.
Citation: Patel HD, Iyoha E, Pierorazio PM .
A systematic review of research gaps in the evaluation and management of localized renal masses.
Urology 2016 Dec;98:14-20. doi: 10.1016/j.urology.2016.08.013.
.
.
Keywords: Cancer, Evidence-Based Practice, Patient-Centered Outcomes Research, Quality Indicators (QIs), Research Methodologies
Kenzik KM, Kent EE, Martin MY
Chronic condition clusters and functional impairment in older cancer survivors: a population-based study.
The purpose of this study was to identify chronic condition clusters at pre- and post-cancer diagnosis, evaluate predictors of developing clusters post-cancer, and examine the impact on functional impairment among older cancer survivors. It found that distinct condition clusters of two or more chronic conditions are prevalent among older cancer survivors. Cluster prevalence increases from pre- to post-cancer diagnosis.
AHRQ-funded; HS023009; HS013852.
Citation: Kenzik KM, Kent EE, Martin MY .
Chronic condition clusters and functional impairment in older cancer survivors: a population-based study.
J Cancer Surviv 2016 Dec;10(6):1096-103. doi: 10.1007/s11764-016-0553-4.
.
.
Keywords: Chronic Conditions, Cancer, Elderly, Research Methodologies, Health Status
Liu L, Huang X, Yaroshinsky A
Joint frailty models for zero-inflated recurrent events in the presence of a terminal event.
The authors proposed two joint frailty models for zero-inflated recurrent events in the presence of a terminal event, combining a logistic model for "structural zero" status and a joint frailty proportional hazards model for recurrent and terminal event times. They applied the two methods to model recurrent opportunistic diseases in the presence of death in an AIDS study and tumor recurrences and a terminal event in a sarcoma study.
AHRQ-funded; HS020263.
Citation: Liu L, Huang X, Yaroshinsky A .
Joint frailty models for zero-inflated recurrent events in the presence of a terminal event.
Biometrics 2016 Mar;72(1):204-14. doi: 10.1111/biom.12376.
.
.
Keywords: Cancer, Data, Research Methodologies