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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 2 of 2 Research Studies DisplayedHochman MJ, Kamal AH, Wolf SP
Anticholinergic drug burden in noncancer versus cancer patients near the end of life.
This article's objective is to determine anticholinergic load (ACL) and its impact in noncancer versus cancer palliative care patients. The authors concluded that ACL is associated with worse fatigue and quality of life and may not differ significantly between cancer and noncancer patients nearing end of life. Symptom management drugs are more responsible for ACL in cancer and noncancer patients, although disease management drugs contribute significantly to ACL in the latter group. They recommend more attention to reducing anticholinergic use in all patients with life-limiting illness.
AHRQ-funded; HS023681.
Citation: Hochman MJ, Kamal AH, Wolf SP .
Anticholinergic drug burden in noncancer versus cancer patients near the end of life.
J Pain Symptom Manage 2016 Nov;52(5):737-43.e3. doi: 10.1016/j.jpainsymman.2016.03.020.
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Keywords: Adverse Drug Events (ADE), Cancer, Medication, Palliative Care, Quality of Life
Amin AP, Wang TY, McCoy L
Impact of bleeding on quality of life in patients on DAPT: insights from TRANSLATE-ACS.
This study sought to determine the incidence of post-percutaneous coronary intervention (PCI) bleeding that occurs on contemporary prolonged dual antiplatelet therapy (DAPT) and its impact on quality of life (QOL). Among patients undergoing PCI for acute myocardial infarction, bleeding during follow-up was associated with worse 6-month utility and QOL
AHRQ-funded; HS022481.
Citation: Amin AP, Wang TY, McCoy L .
Impact of bleeding on quality of life in patients on DAPT: insights from TRANSLATE-ACS.
J Am Coll Cardiol 2016 Jan 5;67(1):59-65. doi: 10.1016/j.jacc.2015.10.034.
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Keywords: Quality of Life, Heart Disease and Health, Adverse Drug Events (ADE), Adverse Events