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AHRQ Research Studies Date
Topics
- (-) Alcohol Use (20)
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 20 of 20 Research Studies DisplayedChavez LJ, Liu CF, Tefft N
The association between unhealthy alcohol use and acute care expenditures in the 30 days following hospital discharge among older Veterans Affairs patients with a medical condition.
Heavy alcohol use could predict increased risk for post-discharge acute care. This study assessed 30-day acute care utilization and expenditures for different categories of alcohol use, using VA and Medicare health care utilization data.
AHRQ-funded; HS022800.
Citation: Chavez LJ, Liu CF, Tefft N .
The association between unhealthy alcohol use and acute care expenditures in the 30 days following hospital discharge among older Veterans Affairs patients with a medical condition.
J Behav Health Serv Res 2017 Oct;44(4):602-24. doi: 10.1007/s11414-016-9529-4..
Keywords: Alcohol Use, Hospital Discharge
Bobb JF, Lee AK, Lapham GT
Evaluation of a pilot implementation to integrate alcohol-related care within primary care.
Researchers and clinical leaders at Kaiser Permanente Washington partnered to design a high-quality Program of Sustained Patient-centered Alcohol-related Care (SPARC). The authors describe the SPARC pilot implementation, evaluate its effectiveness within three large pilot sites, and describe the qualitative findings on barriers and facilitators. They found that alcohol screening increased from 8.9 percent of patients pre-implementation to 62 percent post-implementation.
AHRQ-funded; HS023173.
Citation: Bobb JF, Lee AK, Lapham GT .
Evaluation of a pilot implementation to integrate alcohol-related care within primary care.
Int J Environ Res Public Health 2017 Sep 8;14(9). doi: 10.3390/ijerph14091030.
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Keywords: Alcohol Use, Patient-Centered Healthcare, Patient-Centered Outcomes Research, Primary Care
Kazemi DM, Borsari B, Levine MJ
A systematic review of the mhealth interventions to prevent alcohol and substance abuse.
This systematic review evaluated the recent body of research on mHealth-based interventions for substance use, with aims of (a) examining the functionality and effectiveness of these interventions, (b) evaluating the available research on the effectiveness of these interventions for substance use, and (c) evaluating the design, methodology, results, theoretical grounding, limitations, and implications of each study.
AHRQ-funded; HS023875.
Citation: Kazemi DM, Borsari B, Levine MJ .
A systematic review of the mhealth interventions to prevent alcohol and substance abuse.
J Health Commun 2017 May;22(5):413-32. doi: 10.1080/10810730.2017.1303556.
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Keywords: Alcohol Use, Prevention, Substance Abuse, Telehealth, Young Adults
Bensley KM, Harris AH, Gupta S
Racial/ethnic differences in initiation of and engagement with addictions treatment among patients with alcohol use disorders in the Veterans Health Administration.
In this study, the researchers investigated racial/ethnic variation in initiation of and engagement with specialty addictions treatment in a national sample of Black, Hispanic, and White patients with clinically recognized alcohol use disorders (AUD) from the US Veterans Health Administration (VA). The investigators found, after accounting for facility- and patient-level characteristics, Black and Hispanic patients with AUD were more likely than Whites to initiate specialty addictions treatment, and Black patients were more likely than Whites to engage.
AHRQ-funded; HS013853.
Citation: Bensley KM, Harris AH, Gupta S .
Racial/ethnic differences in initiation of and engagement with addictions treatment among patients with alcohol use disorders in the Veterans Health Administration.
J Subst Abuse Treat 2017 Feb;73:27-34. doi: 10.1016/j.jsat.2016.11.001..
Keywords: Alcohol Use, Racial and Ethnic Minorities, Substance Abuse
Cochran G, Field C, DiClemente C
Latent classes among recipients of a brief alcohol intervention: a replication analysis.
The purpose of this study was to identify differential improvement in alcohol use among injured patients following brief intervention. Increases in both clinical trials for days abstinent were reported by classes characterized by multiple risks and minimal risks. Decreases in volume consumed for both studies were also reported by classes characterized by multiple risks and minimal risks.
AHRQ-funded; HS021394.
Citation: Cochran G, Field C, DiClemente C .
Latent classes among recipients of a brief alcohol intervention: a replication analysis.
Behav Med 2016;42(1):29-38. doi: 10.1080/08964289.2014.951305.
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Keywords: Alcohol Use, Substance Abuse, Behavioral Health, Treatments
Bradley KA, Lapham GT
Is it time for a more ambitious research agenda for decreasing alcohol-related harm among young adults?
The authors commented that brief motivational interviewing-based interventions could probably impact drinking at the population level. They noted that there is a critical need to develop and test more effective interventions and recommended that the public health approach to preventing alcohol-related harm among young adults include known effective approaches, including those that decrease alcohol use by reducing the availability of alcohol.
AHRQ-funded; HS023173.
Citation: Bradley KA, Lapham GT .
Is it time for a more ambitious research agenda for decreasing alcohol-related harm among young adults?
Addiction 2016 Sep;111(9):1531-2. doi: 10.1111/add.13235.
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Keywords: Alcohol Use, Lifestyle Changes, Prevention, Substance Abuse, Young Adults
Clark BJ, Rubinsky AD, Ho PM
Alcohol screening scores and the risk of intensive care unit admission and hospital readmission.
This study sought to determine whether alcohol misuse was associated with admission to an intensive care unit (ICU) among patients receiving outpatient care. Among 486,115 veterans receiving outpatient care, the adjusted probability of ICU admission within 1 year was 2.0 percent for abstinent patients, 1.6 percent for patients with lower-risk alcohol use, 1.8 percent for patients with moderate alcohol misuse, and 2.5 percent for patients with severe alcohol misuse.
AHRQ-funded; HS022800.
Citation: Clark BJ, Rubinsky AD, Ho PM .
Alcohol screening scores and the risk of intensive care unit admission and hospital readmission.
Subst Abus 2016 Jul-Sep;37(3):466-73. doi: 10.1080/08897077.2015.1137259.
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Keywords: Alcohol Use, Hospital Readmissions, Intensive Care Unit (ICU), Ambulatory Care and Surgery, Screening, Substance Abuse
Chavez LJ, Williams EC, Lapham GT
Changes in patient-reported alcohol-related advice following veterans health administration implementation of brief alcohol interventions.
The researchers examined whether an independent measure of brief interventions-patient-reported alcohol-related advice-also increased among VA outpatients who screened positive for alcohol misuse on a mailed survey. They found that among patients with alcohol misuse, the adjusted prevalence of alcohol-related advice increased from 40.4% in 2007 to 55.5% in 2011. Rates of alcohol-related advice increased significantly each year except the last.
AHRQ-funded; HS022800.
Citation: Chavez LJ, Williams EC, Lapham GT .
Changes in patient-reported alcohol-related advice following veterans health administration implementation of brief alcohol interventions.
J Stud Alcohol Drugs 2016 May;77(3):500-8.
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Keywords: Alcohol Use, Behavioral Health, Primary Care, Substance Abuse
Heslin KC, Elixhauser A, Steiner CA
AHRQ Author: Heslin KC, Elixhauser A, Steiner CA
Identifying in-patient costs attributable to the clinical sequelae and comorbidities of alcoholic liver disease in a national hospital database.
The aim of this study was to compare the average costs of hospitalizations with alcoholic liver disease (ALD) and the costs of hospitalizations with other alcohol-related diagnoses that do not involve the liver. It found that costs of hospital care for patients with ALD are higher than those for patients with other alcohol-related diagnoses.
AHRQ-authored.
Citation: Heslin KC, Elixhauser A, Steiner CA .
Identifying in-patient costs attributable to the clinical sequelae and comorbidities of alcoholic liver disease in a national hospital database.
Addiction 2016 May;112(5):782-91. doi: 10.1111/add.13702.
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Keywords: Healthcare Cost and Utilization Project (HCUP), Alcohol Use, Healthcare Costs, Nutrition, Hospitalization
Chavez LJ, Bradley K, Tefft N
Preference weights for the spectrum of alcohol use in the U.S. population.
One barrier to research has been the lack of preference weights needed to calculate Quality Adjusted Life Years (QALYs). Preference weights can be estimated from measures of health-related quality of life (HRQOL). The objective of this study was to describe preference weights for the full spectrum of alcohol use. It concluded that self-reported alcohol consumption may not be associated with preference weights.
AHRQ-funded; HS022800.
Citation: Chavez LJ, Bradley K, Tefft N .
Preference weights for the spectrum of alcohol use in the U.S. population.
Drug Alcohol Depend 2016 Apr 1;161:206-13. doi: 10.1016/j.drugalcdep.2016.02.004.
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Keywords: Medical Expenditure Panel Survey (MEPS), Alcohol Use, Substance Abuse, Health Status
Rentsch C, Tate JP, Akgun KM
Alcohol-related diagnoses and all-cause hospitalization among HIV-infected and uninfected patients: a longitudinal analysis of United States veterans from 1997 to 2011.
From 1997 to 2011, 46,428 HIV-infected and 93,997 uninfected patients were followed for 1,497,536 person-years. Overall hospitalization rates decreased among HIV-infected and uninfected patients. However, cardiovascular and renal insufficiency admissions increased for all groups while gastrointestinal and liver, endocrine, neurologic, and non-AIDS cancer admissions increased among those with an alcohol-related diagnosis.
AHRQ-funded; HS018372.
Citation: Rentsch C, Tate JP, Akgun KM .
Alcohol-related diagnoses and all-cause hospitalization among HIV-infected and uninfected patients: a longitudinal analysis of United States veterans from 1997 to 2011.
AIDS Behav 2016 Mar;20(3):555-64. doi: 10.1007/s10461-015-1025-y.
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Keywords: Alcohol Use, Hospitalization, Human Immunodeficiency Virus (HIV)
Liu L, Strawderman RL, Johnson BA
Analyzing repeated measures semi-continuous data, with application to an alcohol dependence study.
The authors reviewed and considered three extensions of two-part random effects models. They compared the performance through applications to daily drinking records in a secondary data analysis from a randomized controlled trial of topiramate for alcohol dependence treatment. They found that all three models provide a significantly better fit than the log-normal model, and there exists strong evidence for heteroscedasticity.
AHRQ-funded; HS020263.
Citation: Liu L, Strawderman RL, Johnson BA .
Analyzing repeated measures semi-continuous data, with application to an alcohol dependence study.
Stat Methods Med Res 2016 Feb;25(1):133-52. doi: 10.1177/0962280212443324.
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Keywords: Alcohol Use, Behavioral Health, Substance Abuse
Williams EC, Achtmeyer CE, Young JP
Local implementation of alcohol screening and brief intervention at five Veterans Health Administration primary care clinics: Perspectives of clinical and administrative staff.
The researchers conducted a qualitative key informant study to describe local implementation of alcohol screening and brief intervention from the perspectives of frontline adopters in VA primary care . Findings suggest that the local process of implementing alcohol screening and brief intervention may have inadequately addressed important adopter needs.
AHRQ-funded; HS022800.
Citation: Williams EC, Achtmeyer CE, Young JP .
Local implementation of alcohol screening and brief intervention at five Veterans Health Administration primary care clinics: Perspectives of clinical and administrative staff.
J Subst Abuse Treat 2016 Jan;60:27-35. doi: 10.1016/j.jsat.2015.07.011.
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Keywords: Alcohol Use, Screening, Primary Care
Chavez LJ, Liu CF, Tefft N
Unhealthy alcohol use in older adults: association with readmissions and emergency department use in the 30 days after hospital discharge.
This study examined the association between AUDIT-C alcohol screening results and 30-day readmissions or ED visits. Alcohol screening results indicating high-risk drinking that were available in medical records were modestly associated with risk for 30-day readmissions and were not associated with risk for ED visits.
AHRQ-funded; HS022800.
Citation: Chavez LJ, Liu CF, Tefft N .
Unhealthy alcohol use in older adults: association with readmissions and emergency department use in the 30 days after hospital discharge.
Drug Alcohol Depend 2016 Jan;158:94-101. doi: 10.1016/j.drugalcdep.2015.11.008.
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Keywords: Alcohol Use, Elderly, Emergency Department, Hospital Readmissions, Lifestyle Changes
Lapham GT, Rubinsky AD, Williams EC
Decreasing sensitivity of clinical alcohol screening with the AUDIT-C after repeated negative screens in VA clinics.
The purpose of this study was to evaluate the performance of repeat annual clinical alcohol screening in 4 samples of VA outpatients with 1–4 prior consecutive negative annual screens. It found that among patients with repeated negative clinical alcohol screens, the proportion who subsequently screened positive a year later was low and decreased as patients had more prior negative screens.
AHRQ-funded; HS022800.
Citation: Lapham GT, Rubinsky AD, Williams EC .
Decreasing sensitivity of clinical alcohol screening with the AUDIT-C after repeated negative screens in VA clinics.
Drug Alcohol Depend 2014 Sep 1;142:209-15. doi: 10.1016/j.drugalcdep.2014.06.017..
Keywords: Screening, Alcohol Use, Substance Abuse
Jonas DE, Amick HR, Feltner C
Genetic polymorphisms and response to medications for alcohol use disorders: a systematic review and meta-analysis.
This review assessed whether response to medications for alcohol use disorders varies by genotype. It found that estimates of effect for return to heavy drinking suggest it is possible that patients with at least one G allele of A118G polymorphism of OPRM1 might be more likely to respond to naltrexone.
290201200008I; 29032002T
Citation: Jonas DE, Amick HR, Feltner C .
Genetic polymorphisms and response to medications for alcohol use disorders: a systematic review and meta-analysis.
Pharmacogenomics 2014 Sep;15(13):1687-700. doi: 10.2217/pgs.14.121..
Keywords: Medication, Alcohol Use, Substance Abuse, Genetics
Jonas DE, Amick HR, Feltner C
Genetic polymorphisms and response to medications for alcohol use disorders: a systematic review and meta-analysis.
This review assessed whether response to medications for alcohol use disorders varies by genotype. It found that estimates of effect for return to heavy drinking suggest it is possible that patients with at least one G allele of A118G polymorphism of OPRM1 might be more likely to respond to naltrexone.
290201200008I; 29032002T
Citation: Jonas DE, Amick HR, Feltner C .
Genetic polymorphisms and response to medications for alcohol use disorders: a systematic review and meta-analysis.
Pharmacogenomics 2014 Sep;15(13):1687-700. doi: 10.2217/pgs.14.121..
Keywords: Medication, Alcohol Use, Substance Abuse, Genetics
Hartung DM, McCarty D, Fu R
Extended-release naltrexone for alcohol and opioid dependence: a meta-analysis of healthcare utilization studies.
The authors evaluated cost and utilization outcomes between extended-release naltrexone (XR-NTX) and other pharmacotherapies for treatment of alcohol and opioid dependence. They found that alcohol dependent XR-NTX patients had longer medication refill persistence versus acamprosate and oral naltrexone, with healthcare utilization and costs being generally lower or as low for XR-NTX-treated patients relative to other alcohol dependence agents. Opioid dependent XR-NTX patients had lower inpatient substance abuse-related utilization versus other agents and $8170 lower total cost versus methadone.
AHRQ-funded; HS019456.
Citation: Hartung DM, McCarty D, Fu R .
Extended-release naltrexone for alcohol and opioid dependence: a meta-analysis of healthcare utilization studies.
J Subst Abuse Treat 2014 Aug;47(2):113-21. doi: 10.1016/j.jsat.2014.03.007.
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Keywords: Alcohol Use, Comparative Effectiveness, Medication, Opioids, Substance Abuse
Cochran G, Field C, Caetano R
Injury-related consequences of alcohol misuse among injured patients who received screening and brief intervention for alcohol: a latent class analysis.
This study identifies latent classes of intervention recipients based on injury-related consequences and risks of alcohol misuse and then determines which profiles experienced the greatest improvements in drinking. It found that the patients who reported the greatest improvements in drinking following discharge were those characterized by multiple alcohol-related risks and those characterized by a history of alcohol-related accidents and injuries.
AHRQ-funded; HS021394.
Citation: Cochran G, Field C, Caetano R .
Injury-related consequences of alcohol misuse among injured patients who received screening and brief intervention for alcohol: a latent class analysis.
Subst Abus 2014;35(2):153-62. doi: 10.1080/08897077.2013.820679..
Keywords: Alcohol Use, Substance Abuse, Risk
Quanbeck A, Chih MY, Isham A
Mobile delivery of treatment for alcohol use disorders: A review of the literature.
This article explores questions about mobile applications intended for patients dealing with alcohol-use disorders (AUD) s including: What mHealth applications to treat AUDs exist that have been evaluated in the peer-reviewed literature and how can they be categorized? What are common features of these applications? How effective are currently commercially available mHealth applications for AUDs? What are the characteristics, benefits, and limitations of mHealth applications for AUDs?
AHRQ-funded; HS01991702.
Citation: Quanbeck A, Chih MY, Isham A .
Mobile delivery of treatment for alcohol use disorders: A review of the literature.
Alcohol Res 2014;36(1):111-22..
Keywords: Alcohol Use, Health Information Technology (HIT), Substance Abuse, Telehealth