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AHRQ Research Studies Date
Topics
- Access to Care (1)
- Adverse Drug Events (ADE) (6)
- Adverse Events (4)
- Care Management (3)
- Children/Adolescents (1)
- Clinical Decision Support (CDS) (1)
- Clinician-Patient Communication (1)
- Communication (1)
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- Comparative Effectiveness (1)
- Education: Academic (1)
- Education: Continuing Medical Education (3)
- Elderly (3)
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- Implementation (1)
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- Medical Errors (3)
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- Medication: Safety (9)
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- Practice-Based Research Network (PBRN) (1)
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- Provider (5)
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- (-) Provider: Pharmacist (23)
- Racial and Ethnic Minorities (1)
- Social Media (1)
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- Telehealth (3)
- Transitions of Care (1)
- Transplantation (2)
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 23 of 23 Research Studies DisplayedPestka DL, Brummel AR, Wong MT
Characterizing the reach of comprehensive medication management in a population health primary care model.
As care teams adopt team-based models of care, it is important to examine the reach of interdisciplinary services, such as pharmacists providing comprehensive medication management (CMM). This study examined the reach of pharmacist-delivered CMM in the first 10 months of a population health-focused primary care transformation (PCT). This study illustrated that pharmacists providing CMM see complex patients with a high propensity for medication therapy problems.
AHRQ-funded; HS026379.
Citation: Pestka DL, Brummel AR, Wong MT .
Characterizing the reach of comprehensive medication management in a population health primary care model.
J Am Coll Clin Pharm 2021 Nov;4(11):1410-19. doi: 10.1002/jac5.1525..
Keywords: Medication, Care Management, Provider: Pharmacist, Implementation
Taber DJ, Fleming JN, Su Z
Significant hospitalization cost savings to the payer with a pharmacist-led mobile health intervention to improve medication safety in kidney transplant recipients.
This paper examined hospitalization cost savings to the payer with a pharmacist-led mobile health intervention to improve medication safety in kidney transplant recipients. This study was an economic analysis of a 12-month, parallel arm, randomized controlled trial in adult kidney recipients 6 to 36 months posttransplant (NCT03247322). All participants received usual posttransplant care, while the intervention arm received supplemental clinical pharmacist-led medication therapy monitoring and management, via a smartphone-enabled mHealth app, integrated with risk-based televisits.
AHRQ-funded; HS023754.
Citation: Taber DJ, Fleming JN, Su Z .
Significant hospitalization cost savings to the payer with a pharmacist-led mobile health intervention to improve medication safety in kidney transplant recipients.
Am J Transplant 2021 Oct;21(10):3428-35. doi: 10.1111/ajt.16737..
Keywords: Healthcare Costs, Provider: Pharmacist, Telehealth, Health Information Technology (HIT), Transplantation, Hospitalization, Medication: Safety, Medication
Gilson AM, Stone JA, Morris AO
Impact of a pilot community pharmacy system redesign on reducing over-the-counter medication misuse in older adults.
This pilot study’s goal was to decrease misuse of over-the-counter (OTC) medications by older adults aged 65 years or older by creating a pharmacy “Senior Section”. The Senior Section contains a curated selection of OTC medications and it located close to the prescription department to facilitate pharmacy staff-patient engagement to reduce misuse. The study recruited 87 older adults from 3 pharmacies. Misuse outcomes measured were drug-drug, drug-disease, drug-age, and drug-label, with 5 subtypes. The Senior Section reduced drug-label misuse for different models. Misuse was found to decrease after implementation for 7 of 11 comparisons.
AHRQ-funded; HS024490.
Citation: Gilson AM, Stone JA, Morris AO .
Impact of a pilot community pharmacy system redesign on reducing over-the-counter medication misuse in older adults.
J Am Pharm Assoc (2003) 2021 Sep-Oct;61(5):555-64. doi: 10.1016/j.japh.2021.04.007..
Keywords: Elderly, Provider: Pharmacist, Medication, Medication: Safety
Snyder ME, Adeoye-Olatunde OA, Gernant SA
A user-centered evaluation of medication therapy management alerts for community pharmacists: recommendations to improve usability and usefulness.
Community pharmacists provide comprehensive medication reviews (CMRs) through pharmacy contracts with medication therapy management (MTM) vendors. These CMRs are documented in the vendors' web-based MTM software platforms, which often integrate alerts to assist pharmacists in the detection of medication therapy problems. The objectives of this study were to 1) assess the usability and usefulness of MTM alerts for MTM vendor-contracted community pharmacists and 2) generate recommendations for improving MTM alerts for use by community pharmacists.
AHRQ-funded; HS025005.
Citation: Snyder ME, Adeoye-Olatunde OA, Gernant SA .
A user-centered evaluation of medication therapy management alerts for community pharmacists: recommendations to improve usability and usefulness.
Res Social Adm Pharm 2021 Aug;17(8):1433-43. doi: 10.1016/j.sapharm.2020.10.015..
Keywords: Medication, Provider: Pharmacist, Community-Based Practice
De Oliveira GS, Castro-Alves LJ, Kendall MC
Effectiveness of pharmacist intervention to reduce medication errors and health-care resources utilization after transitions of care: a meta-analysis of randomized controlled trials.
The main objective of the current investigation was to examine the effectiveness of pharmacist-based transition-of-care interventions on the reduction of medication errors after hospital discharge. Findings showed that pharmacist transition-of-care intervention is an effective strategy to reduce medication errors after hospital discharge and also reduces subsequent emergency room visits.
AHRQ-funded; HS024158.
Citation: De Oliveira GS, Castro-Alves LJ, Kendall MC .
Effectiveness of pharmacist intervention to reduce medication errors and health-care resources utilization after transitions of care: a meta-analysis of randomized controlled trials.
J Patient Saf 2021 Aug 1;17(5):375-80. doi: 10.1097/pts.0000000000000283..
Keywords: Medication: Safety, Medication, Adverse Drug Events (ADE), Adverse Events, Medical Errors, Patient Safety, Provider: Pharmacist, Transitions of Care
Green TC, Stopka T, Xuan Z
Examining nonprescription syringe sales in Massachusetts and Rhode Island community pharmacies.
The authors sought to describe, compare, and assess the convergent validity of staff-reported nonprescription syringe (NPS) sales volume and NPS administrative sales data from community pharmacies in Massachusetts and Rhode Island. They found that the counts of administrative pharmacy syringe sales data in both states indicated high need, substantial volume, and notable access at community pharmacies. They recommended future research of NPS sales data rather than self-reported data to track emerging trends and to tailor local responses.
AHRQ-funded; HS024021.
Citation: Green TC, Stopka T, Xuan Z .
Examining nonprescription syringe sales in Massachusetts and Rhode Island community pharmacies.
J Am Pharm Assoc 2021 Jul-Aug;61(4):e237-e41. doi: 10.1016/j.japh.2021.03.004..
Keywords: Provider: Pharmacist
Gonzales HM, Fleming JN, Gebregziabher M
Pharmacist-led mobile health intervention and transplant medication safety: a randomized controlled clinical trial.
The goal of this study was to examine the efficacy of improving medication safety through a pharmacist-led, mobile health-based intervention. In this single-center study of adult kidney recipients 6-36 months post-transplant, findings showed that participants receiving the intervention experienced a significant reduction in medication errors and a significantly lower incidence risk of Grade 3 or higher adverse events. The intervention arm also demonstrated significantly lower rates of hospitalizations.
AHRQ-funded; HS023754.
Citation: Gonzales HM, Fleming JN, Gebregziabher M .
Pharmacist-led mobile health intervention and transplant medication safety: a randomized controlled clinical trial.
Clin J Am Soc Nephrol 2021 May 8;16(5):776-84. doi: 10.2215/cjn.15911020..
Keywords: Medication: Safety, Medication, Patient Safety, Transplantation, Telehealth, Health Information Technology (HIT), Provider: Pharmacist, Provider, Medical Errors, Adverse Drug Events (ADE), Adverse Events
Gurwitz JH, Kapoor A, Garber L
Effect of a multifaceted clinical pharmacist intervention on medication safety after hospitalization in persons prescribed high-risk medications: a randomized clinical trial.
The purpose of this study was to determine whether a multifaceted clinical pharmacist intervention improves medication safety for patients who are discharged from the hospital and prescribed medications within 1 or more of these high-risk drug classes: anticoagulants, diabetes agents, and opioids. The randomized clinical trial was conducted at a large multidisciplinary group practice in Massachusetts and included patients 50 years or older. Findings showed that there was not an observed lower rate of adverse drug-related incidents or clinically important medication errors during the posthospitalization period that was associated with a clinical pharmacist intervention.
AHRQ-funded; HS023774.
Citation: Gurwitz JH, Kapoor A, Garber L .
Effect of a multifaceted clinical pharmacist intervention on medication safety after hospitalization in persons prescribed high-risk medications: a randomized clinical trial.
JAMA Intern Med 2021 May;181(5):610-18. doi: 10.1001/jamainternmed.2020.9285..
Keywords: Elderly, Medication: Safety, Medication, Patient Safety, Adverse Drug Events (ADE), Adverse Events, Provider: Pharmacist, Provider
Gilson AM, Xiong KZ, Stone JA
A pharmacy-based intervention to improve safe over-the-counter medication use in older adults.
This study assessed whether the development of a physical redesign that located a curated inventory of lower-risk over-the-counter (OTC) medications proximal to the pharmacy prescription area was helpful to discourage inappropriate use from OTC medications. An area called the Senior Section™ was developed and placed in 4 pharmacies within a single chain. Eight pharmacists and 5 technicians participated in semi-structured interviews which were transcribed. The staff viewed the Senior Section as contributing to notable improvements in proximity, medication safety, convenience, and patient selection behaviors. It also streamlined the coordination of services between pharmacists and technicians and did not interfere with existing pharmacy workflows.
AHRQ-funded; HS024490.
Citation: Gilson AM, Xiong KZ, Stone JA .
A pharmacy-based intervention to improve safe over-the-counter medication use in older adults.
Res Social Adm Pharm 2021 Mar;17(3):578-87. doi: 10.1016/j.sapharm.2020.05.008..
Keywords: Elderly, Medication: Safety, Medication, Patient Safety, Provider: Pharmacist
Snyder ME, Chewning B, Kreling D
An evaluation of the spread and scale of PatientToc™ from primary care to community pharmacy practice for the collection of patient-reported outcomes: a study protocol.
Patient-reported outcomes (PROs), measuring adherence challenges pertaining to both remembering and intention to take medication, offer a rich data source for pharmacists and prescribers to use to resolve medication non-adherence. PatientToc™ is a PROs collection software developed to facilitate collection of PROs data from low-literacy and non-English speaking patients in Los Angeles. This study evaluated the spread and scale of PatientToc™ from primary care to community pharmacies for the collection and use of PROs data pertaining to medication adherence.
AHRQ-funded; HS025943.
Citation: Snyder ME, Chewning B, Kreling D .
An evaluation of the spread and scale of PatientToc™ from primary care to community pharmacy practice for the collection of patient-reported outcomes: a study protocol.
Res Social Adm Pharm 2021 Feb;17(2):466-74. doi: 10.1016/j.sapharm.2020.03.019..
Keywords: Medication, Patient Adherence/Compliance, Primary Care, Provider: Pharmacist, Provider, Health Information Technology (HIT)
Kane-Gill SL, Wong A, Culley CM
JA, et al. Transforming the medication regimen review process using telemedicine to prevent adverse events.
The objective of this study was to determine the impact of pharmacist-led telemedicine services on reducing high-risk medication adverse drug events (ADEs) for nursing home (NH) residents using medication reconciliation and prospective medication regimen reviews (MRRs) on admission plus ongoing clinical decision support alerts throughout the residents' stay. Studying residents in four NHs in Southwestern Pennsylvania, findings showed that the intervention group had a 92% lower incidence of alert-specific ADEs than usual care, and all-cause hospitalization was similar between groups, as were 30-day readmissions.
AHRQ-funded; HS02420.
Citation: Kane-Gill SL, Wong A, Culley CM .
JA, et al. Transforming the medication regimen review process using telemedicine to prevent adverse events.
J Am Geriatr Soc 2021 Feb;69(2):530-38. doi: 10.1111/jgs.16946..
Keywords: Medication: Safety, Medication, Adverse Drug Events (ADE), Adverse Events, Medical Errors, Patient Safety, Telehealth, Health Information Technology (HIT), Provider: Pharmacist, Provider, Clinical Decision Support (CDS), Prevention
Gernant SA, Snyder ME, Jaynes H
The effectiveness of pharmacist-provided telephonic medication therapy management on emergency department utilization in home health patients.
This article's objective is to evaluate the effectiveness of a telephonic medication therapy management (MTM) service on reducing emergency department utilization within a Medicare-insured home health population. The authors found that this pharmacist-delivered telephonic medication therapy management program did not decrease emergency department utilization overall but may further reduce the such risk among patients who are at lower risk of utilization.
AHRQ-funded; HS022119.
Citation: Gernant SA, Snyder ME, Jaynes H .
The effectiveness of pharmacist-provided telephonic medication therapy management on emergency department utilization in home health patients.
J Pharm Technol 2016 Oct 1;32(5):179-84. doi: 10.1177/8755122516660376.
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Keywords: Care Management, Emergency Department, Medication, Patient-Centered Healthcare, Patient-Centered Outcomes Research, Prevention, Provider: Pharmacist, Provider
Pevnick JM, Shane R, Schnipper JL
The problem with medication reconciliation.
The authors discussed medication reconciliation and the issue that benefits reaped by organizations focused on interventions have not generalized easily to other institutions. They specified that medication reconciliation interventions need to be carefully matched to organizational strengths, workflows, and goals based on institutional priorities, and that there are several broad recommendations that can be targeted to organizational leaders, clinicians and investigators.
AHRQ-funded; HS019598; HS023757.
Citation: Pevnick JM, Shane R, Schnipper JL .
The problem with medication reconciliation.
BMJ Qual Saf 2016 Sep;25(9):726-30. doi: 10.1136/bmjqs-2015-004734.
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Keywords: Electronic Health Records (EHRs), Medication, Patient Safety, Provider: Pharmacist
Trogdon JG, Shafer PR, Shah PD
Are state laws granting pharmacists authority to vaccinate associated with HPV vaccination rates among adolescents?
Researchers explored whether state laws allowing pharmacists to administer human papillomavirus (HPV) vaccinations to adolescents are associated with a higher likelihood of HPV vaccine uptake. They concluded that, as currently implemented, state laws allowing pharmacists to administer HPV vaccine to adolescents were not associated with uptake.
AHRQ-funded; HS000032.
Citation: Trogdon JG, Shafer PR, Shah PD .
Are state laws granting pharmacists authority to vaccinate associated with HPV vaccination rates among adolescents?
Vaccine 2016 Aug 31;34(38):4514-19. doi: 10.1016/j.vaccine.2016.07.056.
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Keywords: Children/Adolescents, Infectious Diseases, Policy, Provider: Pharmacist, Vaccination
Augustine J, Warholak TL, Hines LE
Ability and use of comparative effectiveness research by P&T committee members and support staff: a 1-year follow-up.
The study’s objective was to provide a follow-up assessment of the use of comparative effectiveness research (CER) in the pharmacy and therapeutics (P&T) committee decision-making process, using information collected from participants 1 year after attending a live continuing education program. It concluded that health professionals attending a continuing education CER program reported higher use of CER materials compared with nonattendees.
AHRQ-funded; HS019220.
Citation: Augustine J, Warholak TL, Hines LE .
Ability and use of comparative effectiveness research by P&T committee members and support staff: a 1-year follow-up.
J Manag Care Spec Pharm 2016 Jun;22(6):618-25. doi: 10.18553/jmcp.2016.22.6.618.
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Keywords: Comparative Effectiveness, Education: Continuing Medical Education, Provider: Health Personnel, Provider: Pharmacist
Snyder ME, Frail CK, Gernant SA
Fellowships in community pharmacy research: experiences of five schools and colleges of pharmacy.
The researchers described common facilitators, challenges, and lessons learned in 5 schools and colleges of pharmacy in establishing community pharmacy research fellowships. They found that common characteristics across the programs include length of training, prerequisites, graduate coursework, mentoring structure, and immersion into a pharmacist patient care practice. A common challenge has been recruitment, with many programs experiencing at least one year without filling the fellowship position.
AHRQ-funded; HS022119.
Citation: Snyder ME, Frail CK, Gernant SA .
Fellowships in community pharmacy research: experiences of five schools and colleges of pharmacy.
J Am Pharm Assoc 2016 May-Jun;56(3):316-22. doi: 10.1016/j.japh.2015.11.015.
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Keywords: Community-Based Practice, Education: Continuing Medical Education, Provider: Pharmacist
Kennelty KA, Witry MJ, Gehring M
A four-phase approach for systematically collecting data and measuring medication discrepancies when patients transition between health care settings.
This article proposes a four-phase approach for systematically collecting medication data and measuring medication discrepancies between a hospital and community pharmacies. Using this phase-based approach, the study team successfully identified and reported medication discrepancies between a hospital and community pharmacies at the patient, medication, and community pharmacy units of analyses.
AHRQ-funded; HS021984.
Citation: Kennelty KA, Witry MJ, Gehring M .
A four-phase approach for systematically collecting data and measuring medication discrepancies when patients transition between health care settings.
Res Social Adm Pharm 2016 Jul-Aug;12(4):548-58. doi: 10.1016/j.sapharm.2015.09.001..
Keywords: Medication, Medication: Safety, Adverse Drug Events (ADE), Patient Safety, Provider: Pharmacist
Kozak MA, Melton JR, Gernant SA
A needs assessment of unused and expired medication disposal practices: a study from the Medication Safety Research Network of Indiana.
The investigators sought to describe the extent of the unused and expired medication (UEM) issue in Indiana, identify patient beliefs about UEM, and determine any association between those beliefs and various personal and demographic characteristics. They concluded that there remains a need for more disposal locations for both non-controlled and controlled medication.
AHRQ-funded; HS022119.
Citation: Kozak MA, Melton JR, Gernant SA .
A needs assessment of unused and expired medication disposal practices: a study from the Medication Safety Research Network of Indiana.
Res Social Adm Pharm 2016 Mar-Apr;12(2):336-40. doi: 10.1016/j.sapharm.2015.05.013.
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Keywords: Medication: Safety, Medication, Patient Safety, Provider: Pharmacist, Practice-Based Research Network (PBRN)
Lee JL, Choudhry NK, Wu AW
Patient use of email, Facebook, and physician websites to communicate with physicians: a national online survey of retail pharmacy users.
The researchers explored patient behavior and interest in using the Internet to contact physicians. They surveyed CVS customers with at least one chronic condition in the household and found strong interest among patients in the use of email and Facebook to communicate with their physicians. They identified a gap between patient interest and what physicians may currently provide. They suggested the adoption of secure Web messaging systems as a possible solution that addresses both institutional concerns and patient demand.
AHRQ-funded; HS000029.
Citation: Lee JL, Choudhry NK, Wu AW .
Patient use of email, Facebook, and physician websites to communicate with physicians: a national online survey of retail pharmacy users.
J Gen Intern Med 2016 Jan;31(1):45-51. doi: 10.1007/s11606-015-3374-7.
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Keywords: Communication, Health Information Technology (HIT), Clinician-Patient Communication, Provider: Pharmacist, Web-Based
Qato DM, Daviglus ML, Wilder J
'Pharmacy deserts' are prevalent in Chicago's predominantly minority communities, raising medication access concerns.
The authors examined whether trends in the availability of pharmacies varied across communities in Chicago with different racial or ethnic compositions and whether "pharmacy deserts," or low-access neighborhoods, were more common in segregated black and Hispanic communities than elsewhere. They found that in 2012 there were disproportionately more pharmacy deserts in segregated black communities, as well as in low-income communities and federally designated Medically Underserved Areas. These findings suggest that public policies aimed at improving access to prescription medications may need to address factors beyond insurance coverage and medication affordability.
AHRQ-funded; HS021093.
Citation: Qato DM, Daviglus ML, Wilder J .
'Pharmacy deserts' are prevalent in Chicago's predominantly minority communities, raising medication access concerns.
Health Aff 2014 Nov;33(11):1958-65. doi: 10.1377/hlthaff.2013.1397.
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Keywords: Access to Care, Medication, Provider: Pharmacist, Racial and Ethnic Minorities, Urban Health
Werth SR, Sachdeva N, Roberts AW
North Carolina Medicaid recipient management lock-in program: the pharmacist's perspective.
The objectives of this study were (a) evaluate pharmacists’ perceptions of the implementation of the North Carolina (NC) recipient management lock-in program (MLIP) and (b) determine how the beliefs and attitudes of pharmacists could promote or inhibit its success. It concluded that, although possible improvements were identified, the NC MLIP has strong potential for success as it utilizes pharmacists’ medication gate-keeping role, while minimizing the effort required for successful implementation.
AHRQ-funded; HS000032.
Citation: Werth SR, Sachdeva N, Roberts AW .
North Carolina Medicaid recipient management lock-in program: the pharmacist's perspective.
J Manag Care Spec Pharm 2014 Nov;20(11):1122-9..
Keywords: Medicaid, Medication, Opioids, Provider: Pharmacist, Substance Abuse
Snyder ME, Frail CK, Jaynes H
Predictors of medication-related problems among Medicaid patients participating in a pharmacist-provided telephonic medication therapy management program.
The objective of this study was to identify predictors of medication-related problems (MRPs) among Medicaid patients participating in a telephonic medication therapy management (MTM) program. The analysis of study results supports the relative importance of number of medications as a predictor of MRPs in the Medicaid population and identifies other predictors.
AHRQ-funded; HS022119.
Citation: Snyder ME, Frail CK, Jaynes H .
Predictors of medication-related problems among Medicaid patients participating in a pharmacist-provided telephonic medication therapy management program.
Pharmacotherapy 2014 Oct;34(10):1022-32. doi: 10.1002/phar.1462..
Keywords: Adverse Drug Events (ADE), Care Management, Community-Based Practice, Medicaid, Medication, Provider: Pharmacist
Ness GL, Sheehan AH, Snyder ME
Graduating student pharmacists' perspectives on e-professionalism and social media: qualitative findings.
The researchers conducted a cross-sectional survey of 212 graduating student pharmacists to characterize their views of professionalism on popular social media sites. The themes identified in the analysis were separation of personal and professional lives, how accountability for actions should vary by severity, and the extent of representation of the students’ character on social media.
AHRQ-funded; HS022119.
Citation: Ness GL, Sheehan AH, Snyder ME .
Graduating student pharmacists' perspectives on e-professionalism and social media: qualitative findings.
J Am Pharm Assoc 2014 Mar-Apr;54(2):138-43. doi: 10.1331/JAPhA.2014.13188..
Keywords: Education: Academic, Education: Continuing Medical Education, Provider: Pharmacist, Social Media