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AHRQ Research Studies Date
Topics
- Anxiety (3)
- Behavioral Health (5)
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- Children/Adolescents (3)
- Community-Based Practice (1)
- Comparative Effectiveness (1)
- (-) Depression (8)
- Diabetes (1)
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- (-) Patient-Centered Outcomes Research (8)
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 8 of 8 Research Studies DisplayedOrtiz D, Perkins AJ, Fuchita M
Pre-existing anxiety and depression in injured older adults: an under-recognized comorbidity with major health implications.
The purpose of this retrospective post-hoc analysis study was to evaluate variations in baseline depression and anxiety screenings between older injured patients with pre-existing diagnoses and those without. Data from the Trauma Medical Home, a multicenter randomized controlled trial was used for analysis. The study found that almost 50% of the patients screened positive for at least mild depressive symptoms as measured by the Patient Health Questionnaire-9, and 41% of the patients screened positive for at least mild anxiety symptoms as measured by the Generalized Anxiety Disorder Scale. Female patients with a history of concurrent anxiety and depression, greater injury severity scores, and higher Charlson scores were more likely to have mild anxiety at the baseline assessment. Patients with a history of depression only, a prior history of depression and concurrent anxiety, and higher Charlson scores (greater medical comorbidity) were more likely to have experienced at least mild depression at the time of hospital discharge after traumatic injury.
AHRQ-funded; HS026390.
Citation: Ortiz D, Perkins AJ, Fuchita M .
Pre-existing anxiety and depression in injured older adults: an under-recognized comorbidity with major health implications.
Ann Surg Open 2022 Dec; 3(4):e217. doi: 10.1097/as9.0000000000000217..
Keywords: Elderly, Anxiety, Depression, Behavioral Health, Patient-Centered Healthcare, Patient-Centered Outcomes Research, Injuries and Wounds
Ivlev I, Beil TL, Haynes JS
Rapid evidence review of digital cognitive-behavioral therapy for adolescents with depression.
This rapid evidence review was conducted to explore the benefits and harms of digital cognitive-behavioral therapy (dCBT) and the barriers to and facilitators of implementing dCBT for adolescents. An extensive literature review was done through December 6, 2021 for controlled trials conducted in settings highly applicable to the US. Additionally, the authors searched relevant systematic reviews for eligible studies. They identified 12 trials that examined the effects of nine dCBT programs. Overall, dCBT was slightly superior to other therapies in improving depression symptoms immediately, but not at a longer follow-up. There did not appear to be an increased risk for suicidal attempts or ideation with dCBT, however the number of events was very small. Potential barriers to implementing and maintaining dCBT included challenges engaging/retaining patients, developing infrastructure, and training therapists to facilitate dCBT. No data on harms or unintended negative consequences were reported in the included studies.
AHRQ-funded; HS026370.
Citation: Ivlev I, Beil TL, Haynes JS .
Rapid evidence review of digital cognitive-behavioral therapy for adolescents with depression.
J Adolesc Health 2022 Jul;71(1):14-19. doi: 10.1016/j.jadohealth.2022.01.220..
Keywords: Children/Adolescents, Depression, Behavioral Health, Evidence-Based Practice, Patient-Centered Outcomes Research
Brunwasser SM, Garber J
Programs for the prevention of youth depression: evaluation of efficacy, effectiveness, and readiness for dissemination.
This study used the Society for Prevention Research's Standards of Evidence to evaluate the degree to which existing depression prevention programs have established intervention efficacy, effectiveness, and readiness for dissemination. The authors concluded that although several programs have demonstrated promise in terms of efficacy, no depression prevention program for children or adolescents has garnered sufficient evidence of effectiveness under real-world conditions to warrant widespread dissemination.
AHRQ-funded; HS022990.
Citation: Brunwasser SM, Garber J .
Programs for the prevention of youth depression: evaluation of efficacy, effectiveness, and readiness for dissemination.
J Clin Child Adolesc Psychol 2016 Nov-Dec;45(6):763-83. doi: 10.1080/15374416.2015.1020541.
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Keywords: Children/Adolescents, Depression, Evidence-Based Practice, Patient-Centered Outcomes Research
Garber J, Brunwasser SM, Zerr AA
Treatment and prevention of depression and anxiety in youth: test of cross-over effects.
The present meta-analytic review examined whether interventions for children and adolescents that explicitly targeted either anxiety or depression showed treatment specificity or also impacted the other outcome (i.e. cross-over effects). Anxiety prevention studies (n = 14) significantly affected anxious, but not depressive symptoms, indicating no cross-over effect of anxiety prevention trials on depression. For depression prevention studies (n = 15), the effects were not significant for either depressive or anxiety symptoms, although the effect was significantly larger for depressive than for anxious symptoms.
AHRQ-funded; HS022990.
Citation: Garber J, Brunwasser SM, Zerr AA .
Treatment and prevention of depression and anxiety in youth: test of cross-over effects.
Depress Anxiety 2016 Oct;33(10):939-59. doi: 10.1002/da.22519.
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Keywords: Anxiety, Children/Adolescents, Depression, Patient-Centered Outcomes Research
Connolly Gibbons MB, Gallop R, Thompson D
Comparative effectiveness of cognitive therapy and dynamic psychotherapy for major depressive disorder in a community mental health setting: a randomized clinical noninferiority trial.
The authors sought to determine whether dynamic psychotherapy (DT) is not inferior to cognitive therapy (CT) in the treatment of major depressive disorder (MDD) in a community mental health setting. This study suggests that DT is not inferior to CT on change in depression for the treatment of MDD in a community mental health setting.
AHRQ-funded; HS018440.
Citation: Connolly Gibbons MB, Gallop R, Thompson D .
Comparative effectiveness of cognitive therapy and dynamic psychotherapy for major depressive disorder in a community mental health setting: a randomized clinical noninferiority trial.
JAMA Psychiatry 2016 Sep;73(9):904-11. doi: 10.1001/jamapsychiatry.2016.1720.
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Keywords: Comparative Effectiveness, Community-Based Practice, Depression, Behavioral Health, Patient-Centered Outcomes Research
Lin LY, Sidani JE, Shensa A
Association between social media use and depression among U.S. young adults.
The authors assessed the association between social media use and depression in a nationally representative sample of young adults. They found that participants in the highest quartile of total time per day using social media had significantly increased odds of depression. They conluded that social media use was significantly associated with increased depression.
AHRQ-funded; HS022989.
Citation: Lin LY, Sidani JE, Shensa A .
Association between social media use and depression among U.S. young adults.
Depress Anxiety 2016 Apr;33(4):323-31. doi: 10.1002/da.22466.
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Keywords: Social Media, Depression, Young Adults, Behavioral Health, Patient-Centered Outcomes Research
Cummings DM, Kirian K, Howard G
Consequences of comorbidity of elevated stress and/or depressive symptoms and incident cardiovascular outcomes in diabetes: results from the REasons for Geographic And Racial Differences in Stroke (REGARDS) study.
The authors evaluated the impact of comorbid depressive symptoms and/or stress on adverse cardiovascular (CV) outcomes in individuals with diabetes compared with those without diabetes. They concluded that comorbid stress and/or depressive symptoms are common in individuals with diabetes and together are associated with progressively increased risks for adverse CV outcomes.
AHRQ-funded; HS023009.
Citation: Cummings DM, Kirian K, Howard G .
Consequences of comorbidity of elevated stress and/or depressive symptoms and incident cardiovascular outcomes in diabetes: results from the REasons for Geographic And Racial Differences in Stroke (REGARDS) study.
Diabetes Care 2016 Jan;39(1):101-9. doi: 10.2337/dc15-1174.
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Keywords: Cardiovascular Conditions, Depression, Diabetes, Patient-Centered Outcomes Research, Stress
Mooney TK, Gibbons MB, Gallop R
Psychotherapy credibility ratings: patient predictors of credibility and the relation of credibility to therapy outcome.
The researchers examined the relation between credibility ratings for adult psychotherapies and various patient factors as well as the relation between credibility ratings and subsequent symptom change. Their findings indicate that patient beliefs after a brief exposure to treatment may influence symptom improvement. Age and education may influence the patient’s beliefs about the credibility of a treatment.
AHRQ-funded; HS022124.
Citation: Mooney TK, Gibbons MB, Gallop R .
Psychotherapy credibility ratings: patient predictors of credibility and the relation of credibility to therapy outcome.
Psychother Res 2014;24(5):565-77. doi: 10.1080/10503307.2013.847988..
Keywords: Anxiety, Depression, Behavioral Health, Outcomes, Patient-Centered Outcomes Research