National Healthcare Quality and Disparities Report
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AHRQ Research Studies Date
Topics
- Access to Care (1)
- Asthma (1)
- Behavioral Health (2)
- Blood Pressure (1)
- Breast Feeding (1)
- Cancer (3)
- Cancer: Breast Cancer (1)
- Cancer: Colorectal Cancer (1)
- Cancer: Lung Cancer (1)
- Cancer: Ovarian Cancer (1)
- Cancer: Prostate Cancer (3)
- Cardiovascular Conditions (2)
- Case Study (6)
- Children/Adolescents (6)
- Chronic Conditions (1)
- Colonoscopy (1)
- Decision Making (2)
- Evidence-Based Practice (12)
- Eye Disease and Health (1)
- Family Health and History (2)
- Genetics (1)
- Guidelines (8)
- Health Promotion (1)
- Imaging (1)
- Infectious Diseases (2)
- Lifestyle Changes (1)
- Maternal Care (1)
- Medication (1)
- Newborns/Infants (1)
- Nutrition (1)
- Obesity (3)
- Practice Patterns (2)
- Pregnancy (3)
- Prevention (10)
- Primary Care (3)
- Research Methodologies (1)
- Respiratory Conditions (1)
- Risk (2)
- Screening (19)
- Sexual Health (1)
- Sleep Problems (2)
- (-) U.S. Preventive Services Task Force (USPSTF) (27)
- Vitamins and Supplements (1)
- Women (5)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 25 of 27 Research Studies DisplayedNgo-Metzger Q, Gottfredson R
AHRQ Author: Ngo-Metzger Q
Statin use for the primary prevention of cardiovascular disease in adults.
This case study concerns a 66-year-old generally healthy white man, who presents for his annual physical. He has no history of cardiovascular disease (CVD); he has had consistent systolic blood pressure measurements of 140 mm Hg. You calculate his 10-year risk of a CVD event to be 16.7 percent. The case study poses three multiple choice questions together with the U.S. Preventive Services Task Force recommendations and related background information.
AHRQ-authored.
Citation: Ngo-Metzger Q, Gottfredson R .
Statin use for the primary prevention of cardiovascular disease in adults.
Am Fam Physician 2017 Dec 15;96(12):805-06.
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Keywords: Cardiovascular Conditions, Case Study, Medication, Prevention, U.S. Preventive Services Task Force (USPSTF)
Gartlehner G, Patel SV, Feltner C
Hormone therapy for the primary prevention of chronic conditions in postmenopausal women: evidence report and systematic review for the US Preventive Services Task Force.
This review updated evidence for the US Preventive Services Task Force on the benefits and harms of hormone therapy in reducing risks for chronic conditions. It concluded that hormone therapy for the primary prevention of chronic conditions in menopausal women is associated with some beneficial effects but also with a substantial increase of risks for harms. The available evidence regarding benefits and harms of early initiation of hormone therapy is inconclusive.
AHRQ-funded; 290201200015I.
Citation: Gartlehner G, Patel SV, Feltner C .
Hormone therapy for the primary prevention of chronic conditions in postmenopausal women: evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2017 Dec 12;318(22):2234-49. doi: 10.1001/jama.2017.16952.
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Keywords: Chronic Conditions, Evidence-Based Practice, Guidelines, Prevention, U.S. Preventive Services Task Force (USPSTF), Women
Kemper AR, Fan T, Grossman DC
AHRQ Author: Fan T
Gaps in evidence regarding iron deficiency anemia in pregnant women and young children: summary of US Preventive Services Task Force recommendations.
The USPSTF found insufficient evidence to recommend routine iron supplementation for pregnant women or routine screening for iron deficiency anemia in pregnant women or young children. The USPSTF identified a critical evidence gap that is related to whether changing hematologic indexes in otherwise asymptomatic pregnant women or in infants within populations who are reflective of the United States leads to an improvement in maternal or child health outcomes.
AHRQ-authored.
Citation: Kemper AR, Fan T, Grossman DC .
Gaps in evidence regarding iron deficiency anemia in pregnant women and young children: summary of US Preventive Services Task Force recommendations.
Am J Clin Nutr 2017 Dec;106(Suppl 6):1555s-58s. doi: 10.3945/ajcn.117.155788.
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Keywords: Children/Adolescents, Evidence-Based Practice, Maternal Care, U.S. Preventive Services Task Force (USPSTF)
Fan T, Rogers A
AHRQ Author: Fan T
Screening for latent tuberculosis infection in adults.
G.R. is a 21-year-old nonpregnant woman who is new to the area and your office. She is applying to graduate school and wants to make sure her vaccinations are up to date. She reports she is doing well and has no concerns. This case study on tuberculosis screening poses three multiple choice questions together with the U.S. Preventive Services Task Force recommendations and related background information.
AHRQ-authored.
Citation: Fan T, Rogers A .
Screening for latent tuberculosis infection in adults.
Am Fam Physician 2017 Nov 15;96(10):675-76.
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Keywords: Case Study, Infectious Diseases, Screening, U.S. Preventive Services Task Force (USPSTF)
Mabry-Hernandez I, Gottfredson R
AHRQ Author: Mabry-Hernandez I
Screening for lipid disorders in children and adolescents.
This case study concerns a healthy 12-year-old boy presenting for a school physical and well visit. His family history reveals that his maternal grandfather had a heart attack and that his father has started taking a medication for elevated cholesterol levels. His mother is concerned about his genetic risk of a cholesterol disorder and asks if he should be screened. The article poses three multiple choice questions together with the U.S. Preventive Services Task Force recommendations and related background information.
AHRQ-authored.
Citation: Mabry-Hernandez I, Gottfredson R .
Screening for lipid disorders in children and adolescents.
Am Fam Physician 2017 Oct 15;96(8):529-30.
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Keywords: Children/Adolescents, Family Health and History, Screening, U.S. Preventive Services Task Force (USPSTF)
Fan T, Rogers A
AHRQ Author: Fan T
Screening for syphilis infection in nonpregnant adults and adolescents.
R.J. is a 27-year-old man who presents for a well-patient visit. He always keeps his appointments and likes to make sure he is healthy. R.J. has started a new relationship and asks if he should be screened for syphilis. The case study asks a series of three questions based on the USPSTF recommendation statement. Answers are provided.
AHRQ-authored.
Citation: Fan T, Rogers A .
Screening for syphilis infection in nonpregnant adults and adolescents.
Am Fam Physician 2017 Sep 15;96(6):393-94.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Screening, Decision Making, Infectious Diseases, Case Study
Jonas DE, Amick HR, Wallace IF
Vision screening in children aged 6 months to 5 years: Evidence report and systematic review for the US Preventive Services Task Force.
The researchers reviewed the evidence on screening for and treatment of amblyopia, its risk factors, and refractive error in children aged 6 months to 5 years to inform the US Preventive Services Task Force. They concluded that studies directly evaluating the effectiveness of screening were limited and do not establish whether vision screening in preschool children is better than no screening.
AHRQ-funded; 290201200015I.
Citation: Jonas DE, Amick HR, Wallace IF .
Vision screening in children aged 6 months to 5 years: Evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2017 Sep 5;318(9):845-58. doi: 10.1001/jama.2017.9900.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Eye Disease and Health, Children/Adolescents, Screening, Newborns/Infants
Fan T, Amobi A
AHRQ Author: Fan T
Screening for gynecologic conditions with pelvic examination.
A 37-year-old woman presents to your office for her annual wellness visit. She is not due for a Papanicolaou (Pap) smear this year. She is not pregnant, reports no problems, and has no risk factors for sexually transmitted infections. She asks if she should have a pelvic examination today. The case study asks a series of three questions based on the USPSTF recommendation statement. Answers are provided.
AHRQ-authored.
Citation: Fan T, Amobi A .
Screening for gynecologic conditions with pelvic examination.
Am Fam Physician 2017 Aug 15;96(4):253-54.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Women, Case Study, Decision Making, Screening
Misra-Hebert AD, Hu B, Klein EA
Prostate cancer screening practices in a large, integrated health system: 2007-2014.
The researchers assessed prostate cancer screening practices in primary care since the initial United States Preventive Services Task Force (USPSTF) recommendation against prostate-specific antigen (PSA) testing for older men. Prostate cancer screening declined from 2007 to 2014 even in higher-risk groups and follow-up screening rates were not related to previous PSA level.
AHRQ-funded; HS024128.
Citation: Misra-Hebert AD, Hu B, Klein EA .
Prostate cancer screening practices in a large, integrated health system: 2007-2014.
BJU Int 2017 Aug;120(2):257-64. doi: 10.1111/bju.13793.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Cancer: Prostate Cancer, Screening, Primary Care, Practice Patterns
Quattrin Wilfley, DE
The promise and opportunities for screening and treating childhood obesity: USPSTF recommendation statement.
This editorial discusses the updated recommendation statement and evidence review released by the United States Preventive Services Task Force (USPSTF) on screening for obesity in children. The Task Force recommendations are called ‘a call to arms’ against a condition that has immediate as well as long-term consequences for the health of the children affected. The authors note that the evaluation techniques for screening for obesity carry very few risks. Family-based behavioral treatment and the effectiveness of behavioral interventions, as well as pharmacotherapies, are also discussed.
AHRQ-funded; HS022816.
Citation: Quattrin Wilfley, DE .
The promise and opportunities for screening and treating childhood obesity: USPSTF recommendation statement.
JAMA Pediatr 2017 Aug;171(8):733-35. doi: 10.1001/jamapediatrics.2017.1604..
Keywords: Children/Adolescents, Guidelines, Obesity, Prevention, Screening, U.S. Preventive Services Task Force (USPSTF)
McNellis RJ, Thomas S
AHRQ Author: McNellis RJ
Screening for obstructive sleep apnea in adults.
This case study involves a 52-year-old white man who presents to your office for a preventive health visit. He is overweight and has a history of hypertension and hyperlipidemia, which are stable and well controlled with medication. The study poses three multiple choice questions together with the U.S. Preventive Services Task Force recommendations and related background information.
AHRQ-authored.
Citation: McNellis RJ, Thomas S .
Screening for obstructive sleep apnea in adults.
Am Fam Physician 2017 Jul 15;96(2):123-24.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Sleep Problems, Screening, Evidence-Based Practice, Case Study, Guidelines
Patnode CD, Evans CV, Senger CA
Behavioral counseling to promote a healthful diet and physical activity for cardiovascular disease prevention in adults without known cardiovascular disease risk factors: updated evidence report and systematic review for the USPSTF
The researchers systematically reviewed the evidence on the benefits and harms of behavioral counseling for the primary prevention of cardiovascular disease in adults without known cardiovascular risk factors to inform the US Preventive Services Task Force (USPSTF). Diet and physical activity behavioral interventions were found to result in consistent modest benefits across a variety of important intermediate health outcomes across 6 to 12 months, including blood pressure, low-density lipoprotein and total cholesterol levels, and adiposity.
AHRQ-funded; 290201200015I.
Citation: Patnode CD, Evans CV, Senger CA .
Behavioral counseling to promote a healthful diet and physical activity for cardiovascular disease prevention in adults without known cardiovascular disease risk factors: updated evidence report and systematic review for the USPSTF
JAMA 2017 Jul 11;318(2):175-93. doi: 10.1001/jama.2017.3303.
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Keywords: Behavioral Health, Cardiovascular Conditions, Evidence-Based Practice, Health Promotion, Lifestyle Changes, Nutrition, Prevention, Risk, U.S. Preventive Services Task Force (USPSTF)
O'Connor EA, Evans CV, Burda BU
Screening for obesity and intervention for weight management in children and adolescents: evidence report and systematic review for the US Preventive Services Task Force.
The researchers conducted a systematic review of the benefits and harms of screening and treatment for obesity and overweight in children and adolescents to inform the US Preventive Services Task Force. They concluded that lifestyle-based weight loss interventions with 26 or more hours of intervention contact are likely to help reduce excess weight in children and adolescents. The clinical significance of the small benefit of medication use is unclear.
AHRQ-funded; 290201200015IEPC4.
Citation: O'Connor EA, Evans CV, Burda BU .
Screening for obesity and intervention for weight management in children and adolescents: evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2017 Jun 20;317(23):2427-44. doi: 10.1001/jama.2017.0332.
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Keywords: Children/Adolescents, Obesity, Screening, U.S. Preventive Services Task Force (USPSTF)
Meyers D, Duncan J
AHRQ Author: Meyers D
Serologic screening for genital herpes infection.
This case study involves a 23-year-old woman who presents to your office for her first prenatal visit. She is in the eighth week of her first pregnancy. The study poses three multiple choice questions together with the U.S. Preventive Services Task Force recommendations and related background information.
AHRQ-authored.
Citation: Meyers D, Duncan J .
Serologic screening for genital herpes infection.
Am Fam Physician 2017 Jun 15;95(12):801-02.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Screening, Sexual Health, Case Study
Lin JS, Bowles EJA, Williams SB
Screening for thyroid cancer: updated evidence report and systematic review for the US Preventive Services Task Force.
The researchers systematically reviewed the benefits and harms associated with thyroid cancer screening and treatment of early thyroid cancer in asymptomatic adults to inform the US Preventive Services Task Force. They concluded that although ultrasonography of the neck using high-risk sonographic characteristics plus follow-up cytology from fine-needle aspiration can identify thyroid cancers, it is unclear if population-based or targeted screening can decrease mortality rates or improve important patient health outcomes.
AHRQ-funded; 290201200015I.
Citation: Lin JS, Bowles EJA, Williams SB .
Screening for thyroid cancer: updated evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2017 May 9;317(18):1888-903. doi: 10.1001/jama.2017.0562.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Screening, Cancer, Evidence-Based Practice, Guidelines
Henderson JT, Thompson JH, Burda BU
Preeclampsia screening: evidence report and systematic review for the US Preventive Services Task Force.
The researchers systematically reviewed the benefits and harms of preeclampsia screening and risk assessment for the US Preventive Services Task Force. Their review of 21 studies concluded that evidence to estimate benefits and harms of preeclampsia screening and the test performance of different screening approaches over the course of pregnancy was limited. Externally validated risk prediction models had limited applicability.
AHRQ-funded; 290201200151I.
Citation: Henderson JT, Thompson JH, Burda BU .
Preeclampsia screening: evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2017 Apr 25;317(16):1668-83. doi: 10.1001/jama.2016.18315.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Pregnancy, Blood Pressure, Screening, Evidence-Based Practice, Guidelines, Women, Prevention
Bibbins-Domingo K, Whitlock E, Wolff T
AHRQ Author: Wolff T, Ngo-Metzger Q
Developing recommendations for evidence-based clinical preventive services for diverse populations: methods of the U.S. Preventive Services Task Force.
The U.S. Preventive Services Task Force (USPSTF) summarizes the principles and considerations that guide development of its recommendations for diverse U.S. populations. It uses these principles through each step in the evidence-based guideline process: developing the research plan, conducting the evidence review, developing the recommendation, and communicating to guideline users. A comprehensive list of recommendations that includes considerations for specific populations is provided.
AHRQ-authored; AHRQ-funded.
Citation: Bibbins-Domingo K, Whitlock E, Wolff T .
Developing recommendations for evidence-based clinical preventive services for diverse populations: methods of the U.S. Preventive Services Task Force.
Ann Intern Med 2017 Apr 18;166(8):565-71. doi: 10.7326/m16-2656.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Evidence-Based Practice, Prevention, Research Methodologies, Guidelines
Kato E, Rajupet S
AHRQ Author: Kato E
Primary interventions to support breastfeeding.
This case study involves a 26-year-old woman, who presents for a routine prenatal visit at 28 weeks’ gestation. Her medical history is significant for poorly controlled asthma, and her family history is significant for breast cancer diagnosed in her mother. It poses three multiple choice questions together with the U.S. Preventive Services Task Force recommendations and related background information.
AHRQ-authored.
Citation: Kato E, Rajupet S .
Primary interventions to support breastfeeding.
Am Fam Physician 2017 Apr 15;95(8):517-18.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Breast Feeding, Primary Care, Pregnancy, Asthma
Chou R, Bougatsos C, Blazina I
Screening for celiac disease: evidence report and systematic review for the US Preventive Services Task Force.
The researchers reviewed the evidence on benefits and harms of screening for celiac disease in asymptomatic adults, adolescents, and children 3 years and older for the US Preventive Services Task Force. Although some evidence was found regarding diagnostic accuracy of tests for celiac disease, little or no evidence was identified to inform most of the key questions related to benefits and harms of screening for celiac disease in asymptomatic individuals.
AHRQ-funded; 290201200015I.
Citation: Chou R, Bougatsos C, Blazina I .
Screening for celiac disease: evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2017 Mar 28;317(12):1258-68. doi: 10.1001/jama.2016.10395.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Screening, Prevention, Evidence-Based Practice, Guidelines
Guirguis-Blake JM, Henderson JT, Perdue LA
Periodic screening pelvic examination: evidence report and systematic review for the US Preventive Services Task Force.
The researchers systematically reviewed literature on health benefits, accuracy, and harms of the screening pelvic examination for gynecologic conditions for the US Preventive Services Task Force (USPSTF). : No direct evidence was identified for overall benefits and harms of the pelvic examination as a 1-time or periodic screening test. Limited evidence was identified regarding the diagnostic accuracy and harms of routine screening pelvic examinations in asymptomatic primary care populations.
AHRQ-funded.
Citation: Guirguis-Blake JM, Henderson JT, Perdue LA .
Periodic screening pelvic examination: evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2017 Mar 7;317(9):954-66. doi: 10.1001/jama.2016.12819.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Screening, Evidence-Based Practice, Women, Prevention
Jonas DE, Amick HR, Feltner C
Screening for obstructive sleep apnea in adults: evidence report and systematic review for the US Preventive Services Task Force.
The effectiveness of stool-based colorectal cancer (CRC) screening is contingent on colonoscopy completion in patients with an abnormal fecal immunochemical test (FIT). This study found that FIT positive patients never referred to gastroenterology or who missed their appointment after referrals were more likely to have comorbid conditions and documented illicit substance use compared with patients who completed a colonoscopy.
AHRQ-funded; 290201200015I.
Citation: Jonas DE, Amick HR, Feltner C .
Screening for obstructive sleep apnea in adults: evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2017 Jan 24;317(4):415-33. doi: 10.1001/jama.2016.19635.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Screening, Sleep Problems, Evidence-Based Practice, Respiratory Conditions
Viswanathan M, Treiman KA, Kish-Doto J
Folic acid supplementation for the prevention of neural tube defects: an updated evidence report and systematic review for the US Preventive Services Task Force.
This report reviewed the evidence on folic acid supplementation for preventing neural tube defects to inform the US Preventive Services Task Force for an updated Recommendation Statement. In studies conducted before the initiation of food fortification in the United States in 1998, folic acid supplementation provided protection against neural tube defects. Newer postfortification studies have not demonstrated a protective association but have the potential for misclassification and recall bias.
AHRQ-funded; 290201200015I.
Citation: Viswanathan M, Treiman KA, Kish-Doto J .
Folic acid supplementation for the prevention of neural tube defects: an updated evidence report and systematic review for the US Preventive Services Task Force.
JAMA 2017 Jan 10;317(2):190-203. doi: 10.1001/jama.2016.19193.
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Keywords: U.S. Preventive Services Task Force (USPSTF), Pregnancy, Prevention, Evidence-Based Practice, Vitamins and Supplements
Wilfley DE, Staiano AE, Altman M
Improving Access and Systems of Care for Evidence-Based Childhood Obesity Treatment: conference key findings and next steps.
This conference sought ways to improve systems of care to advance implementation of the U.S. Preventive Services Task Force recommendations for childhood obesity treatment and to expand payment for these services. Consensus recommendations for childhood obesity treatment included: family-based multicomponent behavioral therapy; integrated care model; and multidisciplinary care team.
AHRQ-funded; HS022816.
Citation: Wilfley DE, Staiano AE, Altman M .
Improving Access and Systems of Care for Evidence-Based Childhood Obesity Treatment: conference key findings and next steps.
Obesity 2017 Jan;25(1):16-29. doi: 10.1002/oby.21712.
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Keywords: Obesity, Children/Adolescents, U.S. Preventive Services Task Force (USPSTF), Behavioral Health, Access to Care
Smieliauskas F, MacMahon H, Salgia R
Geographic variation in radiologist capacity and widespread implementation of lung cancer CT screening.
The researchers estimated the prevalence of capacity constraints in the radiologist workforce and resulting potential disparities in access to lung cancer screening. They found that scaling up lung cancer screening would increase imaging procedures by an average of 4% across Health Service Areas (HSAs). HSAs that were rural, with many eligible smokers, and disproportionately Hispanic or low-income smokers had significantly higher odds of facing capacity constraints.
AHRQ-funded; HS018535.
Citation: Smieliauskas F, MacMahon H, Salgia R .
Geographic variation in radiologist capacity and widespread implementation of lung cancer CT screening.
J Med Screen 2014 Dec;21(4):207-15. doi: 10.1177/0969141314548055..
Keywords: U.S. Preventive Services Task Force (USPSTF), Cancer, Cancer: Lung Cancer, Screening, Imaging
Elstad EA, Sheridan SL, Lee JG
Have screening harms become newsworthy? News coverage of prostate and colorectal cancer screening since the 2008 USPSTF recommendation changes.
The researchers aimed to determine whether newspapers portrayed screening for prostate and colorectal cancers differently after the 2008 USPSTF recommendation changes. In US newspapers from 2005 to 2012, they found that benefits in prostate cancer screening articles and harms and benefits in colonoscopy articles did not change over time, but mentions of prostate cancer screening harms increased after 2008. They concluded that consumers, especially lay consumers, are receiving unbalanced information on cancer screening.
AHRQ-funded; HS021133; HS000032.
Citation: Elstad EA, Sheridan SL, Lee JG .
Have screening harms become newsworthy? News coverage of prostate and colorectal cancer screening since the 2008 USPSTF recommendation changes.
J Behav Med 2014 Dec;37(6):1242-51. doi: 10.1007/s10865-014-9572-7.
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Keywords: Cancer: Colorectal Cancer, Colonoscopy, Cancer: Prostate Cancer, Screening, U.S. Preventive Services Task Force (USPSTF)