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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 6 of 6 Research Studies DisplayedMaas MB, Francis BA, Sangha RS
Refining prognosis for intracerebral hemorrhage by early reassessment.
The researchers compared the accuracy of a widely used prognostic score against a model derived from clinical data obtained 5 days after admission for patients with intracerebral hemorrhage (ICH), a condition for which prognostication has proven notoriously challenging and prone to bias. They found that a simple reassessment after 5 days of care significantly improves the accuracy of prognosticating outcome in patients with ICH.
AHRQ-funded; HS023437.
Citation: Maas MB, Francis BA, Sangha RS .
Refining prognosis for intracerebral hemorrhage by early reassessment.
Cerebrovasc Dis 2017;43(3-4):110-16. doi: 10.1159/000452679.
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Keywords: Shared Decision Making, Diagnostic Safety and Quality, Patient-Centered Outcomes Research
Pantalone KM, Hobbs TM, Chagin KM
Prevalence and recognition of obesity and its associated comorbidities: cross-sectional analysis of electronic health record data from a large US integrated health system.
The purpose of the study was to determine the prevalence of obesity and its related comorbidities among patients being actively managed at a US academic medical centre, and to examine the frequency of a formal diagnosis of obesity. This cross-sectional summary from a large US integrated health system found that three out of every four patients had overweight or obesity based on BMI. Less than half of patients who were identified as having obesity according to BMI received a formal diagnosis via ICD-9 documentation.
AHRQ-funded; HS024128.
Citation: Pantalone KM, Hobbs TM, Chagin KM .
Prevalence and recognition of obesity and its associated comorbidities: cross-sectional analysis of electronic health record data from a large US integrated health system.
BMJ Open 2017 Nov 16;7(11):e017583. doi: 10.1136/bmjopen-2017-017583..
Keywords: Diagnostic Safety and Quality, Electronic Health Records (EHRs), Health Systems, Obesity, Patient-Centered Outcomes Research
Balentine CJ, Xie R, Kirklin JK
Failure to diagnose hyperparathyroidism in 10,432 patients with hypercalcemia: opportunities for system-level intervention to increase surgical referrals and cure.
Researchers sought to determine whether a significant number of patients with hyperparathyroidism remain undiagnosed and untreated. After reviewing administrative data on 682,704 patients from a tertiary referral center between 2011 and 2015 and identifying hypercalcemia (>10.5 mg/dL) in 10,432 patients, they concluded that a significant proportion of patients with hyperparathyroidism do not undergo appropriate evaluation and surgical referral.
AHRQ-funded; HS023009.
Citation: Balentine CJ, Xie R, Kirklin JK .
Failure to diagnose hyperparathyroidism in 10,432 patients with hypercalcemia: opportunities for system-level intervention to increase surgical referrals and cure.
Ann Surg 2017 Oct;266(4):632-40. doi: 10.1097/sla.0000000000002370.
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Keywords: Diagnostic Safety and Quality, Patient-Centered Outcomes Research, Surgery
Donnelly JP, Safford MM, Shapiro NI
Application of the Third International Consensus Definitions for Sepsis (Sepsis-3) Classification: a retrospective population-based cohort study.
The Consensus Definitions present clinical criteria for the classification of patients with sepsis. Researchers investigated incidence and long-term outcomes of patients diagnosed with these classifications, which are currently unknown. Their findings support the use of the elevated sepsis-related organ failure assessment (SOFA) score from Sepsis-3, and elevated quick SOFA (qSOFA) score from Sepsis-3 classifications to identify patients with infection who are at elevated risk of poor outcomes.
AHRQ-funded; HS013852.
Citation: Donnelly JP, Safford MM, Shapiro NI .
Application of the Third International Consensus Definitions for Sepsis (Sepsis-3) Classification: a retrospective population-based cohort study.
Lancet Infect Dis 2017 Jun;17(6):661-70. doi: 10.1016/s1473-3099(17)30117-2.
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Keywords: Sepsis, Diagnostic Safety and Quality, Patient-Centered Outcomes Research, Outcomes
Kwa MC, Ardalan K, Laumann AE
Validation of International Classification of Diseases codes for the epidemiologic study of dermatomyositis.
The authors assessed the validity of using ICD-9-CM code 710.3 to identify adult patients with dermatomyositis in outpatient and inpatient settings. They found that one or more occurrences of ICD-9 code 710.3 is insufficient to support the diagnosis of dermatomyositis in the outpatient setting, but that ICD-9 710.3 codes appear to be valid in the inpatient setting.
AHRQ-funded; HS023011.
Citation: Kwa MC, Ardalan K, Laumann AE .
Validation of International Classification of Diseases codes for the epidemiologic study of dermatomyositis.
Arthritis Care Res 2017 May;69(5):753-57. doi: 10.1002/acr.23010.
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Keywords: Diagnostic Safety and Quality, Patient-Centered Outcomes Research, Skin Conditions
Dood RL, Gracia CR, Sammel MD
Endometrial cancer after endometrial ablation vs medical management of abnormal uterine bleeding.
The authors investigated whether endometrial ablation is associated with increased risk or delayed diagnosis of endometrial cancer compared with medical management of abnormal uterine bleeding. They observed no difference in endometrial cancer rates, nor was there a delay in diagnosis when comparing endometrial ablation vs medical management.
AHRQ-funded; HS021336.
Citation: Dood RL, Gracia CR, Sammel MD .
Endometrial cancer after endometrial ablation vs medical management of abnormal uterine bleeding.
J Minim Invasive Gynecol 2014 Sep-Oct;21(5):744-52. doi: 10.1016/j.jmig.2014.02.012.
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Keywords: Cancer, Comparative Effectiveness, Diagnostic Safety and Quality, Patient-Centered Outcomes Research, Women