National Healthcare Quality and Disparities Report
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AHRQ Research Studies Date
Topics
- Behavioral Health (2)
- Cardiovascular Conditions (7)
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- Dementia (1)
- Diabetes (2)
- Disparities (2)
- Elderly (1)
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- Obesity: Weight Management (1)
- Opioids (2)
- Outcomes (8)
- Patient-Centered Outcomes Research (1)
- Patient Adherence/Compliance (1)
- Pregnancy (1)
- Prevention (1)
- Racial and Ethnic Minorities (5)
- Risk (2)
- (-) Sex Factors (17)
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- Stress (1)
- Stroke (2)
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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 17 of 17 Research Studies DisplayedMcCoy RG, Van Houten HK, Dunlay SM
Race and sex differences in the initiation of diabetes drugs by privately insured US adults.
The authors examined the differences in the use of three glucose-lowering medications as a function of both sex and race. They found that, compared to white men, GLP-1RA were 43% more likely to be started by White women, 12% more likely to be started by non-White men, and 21% less likely to be started by non-White women. SGLT2i were at least 10% less likely to be started by all groups compared to White men, and DPP4i were used more often by non-White than White patients of both sexes.
AHRQ-funded; HS024075.
Citation: McCoy RG, Van Houten HK, Dunlay SM .
Race and sex differences in the initiation of diabetes drugs by privately insured US adults.
Race and sex differences in the initiation of diabetes drugs by privately insured US adults..
Keywords: Diabetes, Chronic Conditions, Medication, Sex Factors, Racial and Ethnic Minorities
Mody P, Pandey A, Slutsky AS
AHRQ Author: Bierman AS
Gender-based differences in outcomes among resuscitated patients with out-of-hospital cardiac arrest.
In this study, the investigators examined gender based differences in outcomes among resuscitated patients with out-of-hospital cardiac arrest. Studies examining gender-based differences in outcomes of out-of-hospital cardiac arrest patients have demonstrated that despite a higher likelihood of return of spontaneous circulation, women do not have higher survival. The investigators concluded that among resuscitated out-of-hospital cardiac arrest patients, discharge to survival was significantly lower in women compared with men especially among patients considered to have a favorable prognosis.
AHRQ-authored.
Citation: Mody P, Pandey A, Slutsky AS .
Gender-based differences in outcomes among resuscitated patients with out-of-hospital cardiac arrest.
Circulation 2021 Feb 16;143(7):641-49. doi: 10.1161/circulationaha.120.050427..
Keywords: Sex Factors, Heart Disease and Health, Cardiovascular Conditions, Outcomes
Thompson HM
Stakeholder experiences with gender identity data capture in electronic health records: implementation effectiveness and a visibility paradox.
Advocates have endorsed transgender visibility via gender identity (GI) data capture with the advent of the Affordable Care Act and electronic health record (EHR) requirements. Visibility in data in order to enumerate a population contrasts with ways in which other LGBT and public health scholars have deployed these concepts. This article aims to assess the effectiveness of GI data capture in EHRs and implications for trans health care quality improvements and research.
AHRQ-funded; HS026385.
Citation: Thompson HM .
Stakeholder experiences with gender identity data capture in electronic health records: implementation effectiveness and a visibility paradox.
Health Educ Behav 2021 Feb;48(1):93-101. doi: 10.1177/1090198120963102.
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Keywords: Electronic Health Records (EHRs), Health Information Technology (HIT), Health Services Research (HSR), Vulnerable Populations, Sex Factors
Khodneva Y, Richman J, Kertesz S
Gender differences in association of prescription opioid use and mortality: a propensity-matched analysis from the REasons for Geographic And Racial Differences in Stroke (REGARDS) prospective cohort.
Prescription opioids (PO) have been widely used for chronic non-cancer pain, with commensurate concerns for overdose. The long-term effect of these medications on non-overdose mortality in the general population remains poorly understood. This study's objective was to examine the association of prescription opioid use and mortality in a large cohort, accounting for gender differences and concurrent benzodiazepine use, and using propensity score matching.
AHRQ-funded; HS013852.
Citation: Khodneva Y, Richman J, Kertesz S .
Gender differences in association of prescription opioid use and mortality: a propensity-matched analysis from the REasons for Geographic And Racial Differences in Stroke (REGARDS) prospective cohort.
Subst Abus 2021;42(1):94-103. doi: 10.1080/08897077.2019.1702609..
Keywords: Stroke, Cardiovascular Conditions, Sex Factors, Opioids, Medication, Mortality
Sutherland S, Brunwasser SM
Sex differences in vulnerability to prenatal stress: a review of the recent literature.
This review evaluates the degree to which recent studies provide evidence that prenatal maternal stress (PNMS) has a varying effect on child health outcomes depending on the child's biological sex. “Stress” includes negative life events, psychological stress, and established stress biomarkers. A review of 50 peer-reviewed articles revealed that most found evidence of either sex-specific associations or significant PNMS (x) stress interactions for at least one outcome. Sex-dependent effects were strongest in the group of studies that evaluated child neural/nervous system development and temperament.
AHRQ-funded; HS022990.
Citation: Sutherland S, Brunwasser SM .
Sex differences in vulnerability to prenatal stress: a review of the recent literature.
Sex differences in vulnerability to prenatal stress: a review of the recent literature.
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Keywords: Children/Adolescents, Newborns/Infants, Outcomes, Pregnancy, Sex Factors, Stress
Donato KM, Leon-Perez G, Wallston KA
Something old, something new: when gender matters in the relationship between social support and health.
This paper investigated how social support differentially benefitted self-rated health among men and women hospitalized with heart disease. They found that gender differentiated the effect of nonmarital family contact on health but only when heart disease was newly diagnosed. When newly diagnosed, more frequent contact with family was associated with better self-rated health for women but not men.
AHRQ-funded; HS024898.
Citation: Donato KM, Leon-Perez G, Wallston KA .
Something old, something new: when gender matters in the relationship between social support and health.
J Health Soc Behav 2018 Sep;59(3):352-70. doi: 10.1177/0022146518789362..
Keywords: Cardiovascular Conditions, Hospitalization, Sex Factors
Angraal S, Khera R, Wang Y
Sex and race differences in the utilization and outcomes of coronary artery bypass grafting among Medicare beneficiaries, 1999-2014.
The authors sought to evaluate how the use of coronary artery bypass grafting (CABG) and its outcomes have evolved in different sex and racial subgroups. Using Medicare data, they found that women and black patients had persistently higher CABG mortality than men and white patients, respectively, despite greater declines over the time period. The authors conclude that these findings indicate progress, but further progress is needed.
AHRQ-funded; HS023000.
Citation: Angraal S, Khera R, Wang Y .
Sex and race differences in the utilization and outcomes of coronary artery bypass grafting among Medicare beneficiaries, 1999-2014.
J Am Heart Assoc 2018 Jul 12;7(14). doi: 10.1161/jaha.118.009014..
Keywords: Cardiovascular Conditions, Elderly, Evidence-Based Practice, Heart Disease and Health, Healthcare Utilization, Medicare, Outcomes, Patient-Centered Outcomes Research, Racial and Ethnic Minorities, Sex Factors
Gilmore-Bykovskyi A, Johnson R, Walljasper L
Underreporting of gender and race/ethnicity differences in NIH-funded dementia caregiver support interventions.
The objective of this study was to determine the inclusion and reporting rates among NIH-funded dementia caregiver support interventions. Findings suggested limited NIH guideline compliance that may reflect a lack of awareness regarding potential gender disparities in caregiving roles. In order to ensure NIH guideline compliance, shared investments from researchers, editors, and reviewers to make certain that group differences are systematically identified and reported are recommended.
AHRQ-funded; HS022548.
Citation: Gilmore-Bykovskyi A, Johnson R, Walljasper L .
Underreporting of gender and race/ethnicity differences in NIH-funded dementia caregiver support interventions.
Am J Alzheimers Dis Other Demen 2018 May;33(3):145-52. doi: 10.1177/1533317517749465..
Keywords: Caregiving, Sex Factors, Racial and Ethnic Minorities, Guidelines, Dementia, Disparities
Marsh JC, Park K, Lin YA
Gender differences in trends for heroin use and nonmedical prescription opioid use, 2007-2014.
This study uses National Survey on Drug Use and Health (NSDUH) data to study gender differences in trends for heroin use and nonmedical prescription opioid use from 2007-2014. There has been a steady decline in nonmedical prescription heroin use but a notable increase in heroin use during this period for both men and women. However, women are increasing heroin use at a faster rate than men but their nonmedical prescription opioid use is not decreasing as fast as men. The researchers conclude that more study is needed on gender differences in use and treatment access.
AHRQ-funded; HS000084.
Citation: Marsh JC, Park K, Lin YA .
Gender differences in trends for heroin use and nonmedical prescription opioid use, 2007-2014.
J Subst Abuse Treat 2018 Apr;87:79-85. doi: 10.1016/j.jsat.2018.01.001..
Keywords: Medication, Opioids, Sex Factors, Substance Abuse
Lau KSL, Rosenman MB, Wiehe SE
Race/ethnicity, and behavioral health status: first arrest and outcomes in a large sample of juvenile offenders.
The objective of this study was to assess the simultaneous effects of gender, race/ethnicity, and pre-arrest behavioral health (BH) service-use on age at first arrest, and first arrest outcomes. It found that black youth were arrested at younger ages than white or Hispanic youth. Youth with psychiatric problems were arrested at younger ages than youth with substance-use, dual-diagnoses, or no BH problems.
AHRQ-funded; HS024296; HS023318.
Citation: Lau KSL, Rosenman MB, Wiehe SE .
Race/ethnicity, and behavioral health status: first arrest and outcomes in a large sample of juvenile offenders.
J Behav Health Serv Res 2018 Apr;45(2):237-51. doi: 10.1007/s11414-017-9578-3.
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Keywords: Behavioral Health, Outcomes, Racial and Ethnic Minorities, Sex Factors
Gupta A, Barrabes JA, Strait K
Sex differences in timeliness of reperfusion in young patients with ST-segment-elevation myocardial infarction by initial electrocardiographic characteristics.
Investigators aimed to determine the electrocardiographic correlates of delay in reperfusion in young patients with ST-segment-elevation myocardial infarction. They found that sex disparities in timeliness to reperfusion in young patients with ST-segment-elevation myocardial infarction persisted, despite adjusting for initial electrocardiographic characteristics. They concluded that left ventricular hypertrophy by voltage criteria and absence of prehospital ECG are strongly positively correlated and ST elevation in lateral leads is negatively correlated with reperfusion delay.
AHRQ-funded; HS023000.
Citation: Gupta A, Barrabes JA, Strait K .
Sex differences in timeliness of reperfusion in young patients with ST-segment-elevation myocardial infarction by initial electrocardiographic characteristics.
J Am Heart Assoc 2018 Mar 7;7(6). doi: 10.1161/jaha.117.007021..
Keywords: Sex Factors, Heart Disease and Health, Cardiovascular Conditions, Disparities
Kochkodan J, Telem DA, Ghaferi AA
Physiologic and psychological gender differences in bariatric surgery.
This paper aims to describe differences in bariatric surgery outcomes by gender and to understand the physiologic and psychological differences that may explain this gender gap. It concludes that, despite significantly lower weight loss and increased complication rates, males tend to have markedly higher satisfaction and psychological well-being scores than females.
AHRQ-funded; HS023621; HS024403.
Citation: Kochkodan J, Telem DA, Ghaferi AA .
Physiologic and psychological gender differences in bariatric surgery.
Surg Endosc 2018 Mar;32(3):1382-88. doi: 10.1007/s00464-017-5819-z.
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Keywords: Obesity, Outcomes, Sex Factors, Surgery, Obesity: Weight Management
Sun CJ, Seloilwe ES, Magowe M
Gender differences in sexual and reproductive health protective and risk factors of Batswana adolescents: implications for parent and adolescent interventions.
The HIV epidemic continues in sub-Saharan Africa and Botswana and adolescents there have borne the brunt. This analysis assessed gender differences in sexual and reproductive health protective and risk factors in 228 Batswana adolescents. Although three-quarters of adolescents prefer to have their parents teach them about sex, it is the fourth most common source of information.
AHRQ-funded; HS022981.
Citation: Sun CJ, Seloilwe ES, Magowe M .
Gender differences in sexual and reproductive health protective and risk factors of Batswana adolescents: implications for parent and adolescent interventions.
AIDS Educ Prev 2018 Feb;30(1):35-46. doi: 10.1521/aeap.2018.30.1.35..
Keywords: Caregiving, Children/Adolescents, Human Immunodeficiency Virus (HIV), Prevention, Risk, Sex Factors, Sexual Health
Dakwar E, Levin FR, Olfson M
First treatment contact for ADHD: predictors of and gender differences in treatment seeking.
The investigators aimed to estimate ADHD treatment-seeking probabilities over the lifetime and to identify predictors of treatment seeking for ADHD separately for males and females. They found that a large proportion of persons with ADHD do not seek treatment, and that treatment seeking by males was affected by a greater number of identifiable characteristics, suggesting that males might be more responsive to efforts directed toward expediting treatment entry.
AHRQ-funded; HS016097.
Citation: Dakwar E, Levin FR, Olfson M .
First treatment contact for ADHD: predictors of and gender differences in treatment seeking.
Psychiatr Serv 2014 Dec;65(12):1465-73. doi: 10.1176/appi.ps.201300298.
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Keywords: Behavioral Health, Sex Factors, Patient Adherence/Compliance
Duffy RP, Adams JE, Callas PW
The influence of gender on functional outcomes of lower extremity bypass.
The researchers aimed to evaluate the effect of gender on early and late procedural and functional outcomes of lower extremity bypass (LEB). They found that women have complication rates similar to men with inferior early and late functional outcomes after LEB. The reduced patency rates in women with critical limb ischemia did not translate into differences in limb salvage.
AHRQ-funded; HS021581.
Citation: Duffy RP, Adams JE, Callas PW .
The influence of gender on functional outcomes of lower extremity bypass.
J Vasc Surg 2014 Nov;60(5):1282-90, 90.e1. doi: 10.1016/j.jvs.2014.05.008.
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Keywords: Cardiovascular Conditions, Outcomes, Sex Factors, Surgery
Strom Williams JL, Lynch CP, Winchester R
Gender differences in composite control of cardiovascular risk factors among patients with type 2 diabetes.
This study examined the gender differences in multiple cardiovascular disease (CVD) risk factor control in adults with type 2 diabetes seen in diverse clinical settings. It found that women had significantly poorer composite control of CVD risk outcomes compared with men, adjusting for relevant confounding factors. In unadjusted analyses, women had higher mean systolic blood pressure and LDL cholesterol levels compared with men.
AHRQ-funded; HS011418.
Citation: Strom Williams JL, Lynch CP, Winchester R .
Gender differences in composite control of cardiovascular risk factors among patients with type 2 diabetes.
Diabetes Technol Ther 2014 Jul;16(7):421-7. doi: 10.1089/dia.2013.0329..
Keywords: Cardiovascular Conditions, Risk, Diabetes, Outcomes, Sex Factors
Boehme AK, Siegler JE, Mullen MT
Racial and gender differences in stroke severity, outcomes, and treatment in patients with acute ischemic stroke.
This study sought to determine the association of race and gender on initial stroke severity, thrombolysis, and functional outcome after acute ischemic stroke (AIS). The investigators concluded that race and gender were not significantly associated with short-term outcome, although black women were significantly less likely to be treated with tissue plasminogen activator (tPA). Black women had more tPA exclusions than any other group. The primary reason for tPA exclusion in this study was not arriving within 3 hours of stroke symptom onset.
AHRQ-funded; HS013852.
Citation: Boehme AK, Siegler JE, Mullen MT .
Racial and gender differences in stroke severity, outcomes, and treatment in patients with acute ischemic stroke.
J Stroke Cerebrovasc Dis 2014 Apr;23(4):e255-61. doi: 10.1016/j.jstrokecerebrovasdis.2013.11.003..
Keywords: Racial and Ethnic Minorities, Outcomes, Sex Factors, Stroke