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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 3 of 3 Research Studies DisplayedParker WF, Georges RJ, Gao YN
Association between groundwater lithium and the diagnosis of bipolar disorder and dementia in the United States.
This study examined the association between groundwater lithium and the diagnoses of bipolar disorder and dementia in the United States, with adjustment for local health care resources and demographics. Data on groundwater lithium concentrations was collected by the US Geological Survey, and diagnoses were identified from inpatient hospital, long-term care, and other therapy claims files from several sources. The results of the study indicate that, in spite of the substantial variations in groundwater lithium exposure, no significant association between exposure and the risk of bipolar disorder or dementia after adjustment for county-level demographics and health care resource was found. The authors note that therapeutic lithium doses are orders of magnitude larger than groundwater lithium concentrations, which makes a true causal relationship between groundwater lithium and mental health dubious.
AHRQ-funded; HS000084.
Citation: Parker WF, Georges RJ, Gao YN .
Association between groundwater lithium and the diagnosis of bipolar disorder and dementia in the United States.
JAMA Psychiatry 2018 Jul;75(7):751-54. doi: 10.1001/jamapsychiatry.2018.1020..
Keywords: Dementia, Behavioral Health, Neurological Disorders, Risk
Olfson M, Wall M, Wang S
Suicide after deliberate self-harm in adolescents and young adults.
This study’s objective was to identify risk factors for repeated nonfatal self-harm and suicide death among adolescents and young adults, using a national cohort of patients in the Medicaid program who were followed for up to 1 year after initial self-harm. Data on cause of death was obtained from the National Death Index. The results of the study indicated that adolescents and young adults showed a markedly elevated risk of suicide after nonfatal self-harm. The 12-month suicide standardized mortality rate ratio after self-harm was significantly higher for adolescents than young adults. Hazards of suicide after self-harm were also higher for American Indians and Alaskan natives than for non-Hispanic white patients and for those self-harm patients who initially used violent methods, particularly firearms. The authors conclude that these results underscore the importance of follow-up care to help ensure the safety of self-harm patients.
AHRQ-funded; HS021112.
Citation: Olfson M, Wall M, Wang S .
Suicide after deliberate self-harm in adolescents and young adults.
Pediatrics 2018 Apr;141(4). doi: 10.1542/peds.2017-3517..
Keywords: Children/Adolescents, Medicaid, Behavioral Health, Risk, Young Adults
Chambers C, Chiu S, Scott AN
Factors associated with poor mental health status among homeless women with and without dependent children.
The researchers estimated the prevalence of mental health problems among homeless women as well as the effects of risk factors on those problems. They found that, in a group of 522 homeless women in Toronto, Canada, poor mental health was associated with low perceived access to social support, physical/sexual assault in the past 12 months, presence of a chronic health condition, and presence of a drug use problem.
AHRQ-funded; HS014129
Citation: Chambers C, Chiu S, Scott AN .
Factors associated with poor mental health status among homeless women with and without dependent children.
Community Ment Health J. 2014 Jul;50(5):553-9. doi: 10.1007/s10597-013-9605-7..
Keywords: Behavioral Health, Chronic Conditions, Social Determinants of Health, Risk