National Healthcare Quality and Disparities Report
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AHRQ Research Studies Date
Topics
- Cancer (6)
- Cancer: Colorectal Cancer (4)
- (-) Cancer: Prostate Cancer (22)
- Case Study (1)
- Clinician-Patient Communication (1)
- Colonoscopy (1)
- Comparative Effectiveness (2)
- Decision Making (2)
- Disparities (2)
- Elderly (2)
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- Healthcare Utilization (2)
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- Mortality (2)
- Outcomes (2)
- Patient-Centered Healthcare (1)
- Patient-Centered Outcomes Research (4)
- Patient and Family Engagement (1)
- Payment (1)
- Practice Patterns (3)
- Prevention (1)
- Primary Care (3)
- Quality Measures (2)
- Racial and Ethnic Minorities (3)
- Risk (1)
- Screening (7)
- Sexual Health (1)
- Substance Abuse (1)
- Surgery (2)
- Treatments (1)
- U.S. Preventive Services Task Force (USPSTF) (2)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 22 of 22 Research Studies DisplayedReeve BB, Wang M, Weinfurt K
Psychometric evaluation of PROMIS sexual function and satisfaction measures in a longitudinal population-based cohort of men with localized prostate cancer.
The purpose of this study was to evaluate the psychometric properties of the Patient-Reported Outcomes Measurement Information System (PROMIS) Sexual Function and Satisfaction (SexFS) measures. A population-based cohort of men with localized prostate cancer who were living in North Carolina and who could self-report their health-related quality of life in English completed surveys via phone interviews prior to treatment and at 3, 12, and 24 months after cancer treatment initiation. The researchers’ hypothesis was that men undergoing prostatectomy surgery would report the poorest sexual function at the 3-month survey. The study concludes that use of the PROMIS SexFS measures to assess sexual interest, erectile function, and satisfaction is strongly supported, and that these measures may be useful to identify effective interventions to treat sexual dysfunction and monitor sexual functioning in men with localized prostate cancer over time.
AHRQ-funded; 29020050040ITO6.
Citation: Reeve BB, Wang M, Weinfurt K .
Psychometric evaluation of PROMIS sexual function and satisfaction measures in a longitudinal population-based cohort of men with localized prostate cancer.
J Sex Med 2018 Dec;15(12):1792-810. doi: 10.1016/j.jsxm.2018.09.015..
Keywords: Cancer: Prostate Cancer, Men's Health, Sexual Health
Skolarus TA, Caram ME, Chapman CH
Castration remains despite decreasing definitive treatment of localized prostate cancer in the elderly: a case for de-implementation.
In this editorial, the authors discuss a study by Yang, et al., published in 2017 in Cancer, in which they used the National Cancer Data Base to examine definitive therapy (prostatectomy or radiotherapy) among 400,000 patients who were diagnosed with intermediate-risk or high-risk prostate cancer between 2004 and 2012.
AHRQ-funded; HS025707.
Citation: Skolarus TA, Caram ME, Chapman CH .
Castration remains despite decreasing definitive treatment of localized prostate cancer in the elderly: a case for de-implementation.
Cancer 2018 Oct 15;124(20):3971-74. doi: 10.1002/cncr.31665..
Keywords: Cancer: Prostate Cancer, Elderly, Men's Health
Wolff T, Jadotte YJ
AHRQ Author: Wolff T
Screening for prostate cancer.
This case study describes a 57-year-old black man, non-smoker, who has a history of diabetes mellitus, currently well-controlled. He would like to discuss the prostate-specific antigen (PSA) test even though he has no family history of prostate cancer. The case study questions are based on USPSTF recommendations for prostate cancer screening.
AHRQ-authored.
Citation: Wolff T, Jadotte YJ .
Screening for prostate cancer.
Am Fam Physician 2018 Oct 15;98(8):537-38..
Keywords: Cancer: Prostate Cancer, Case Study, Guidelines, Prevention, Screening
Modi PK, Kaufman SR, Qi J
National trends in active surveillance for prostate cancer: validation of medicare claims-based algorithms.
This study analyzed the use of active surveillance of low-risk prostate cancer among a wide variety of health care practices. Researchers identified men with prostate cancer from 2012-2014 using a 100% sample of Michigan Medicare data and linked them with the Michigan Urologic Surgery Improvement Collaborative (MUSIC) registry. They analyzed the performance of 8 claims-based algorithms that were used and selected 3 of them to apply to a 20% national Medicare sample. The 3 algorithms were determined to be either the most sensitive, the most specific, and a balanced algorithm incorporating age and comorbidity. They found that use of surveillance for men increased from 2007 to 2014 but there was a large decrease in the rate of prostate cancer diagnosis. The rate of active surveillance either increased or remained stable depending on the algorithm used.
AHRQ-funded; HS025707.
Citation: Modi PK, Kaufman SR, Qi J .
National trends in active surveillance for prostate cancer: validation of medicare claims-based algorithms.
Urology 2018 Oct;120:96-102. doi: 10.1016/j.urology.2018.06.037..
Keywords: Cancer, Cancer: Prostate Cancer, Medicare, Men's Health, Payment
Lee DJ, Zhao Z, Huang LC
Racial variation in receipt of quality radiation therapy for prostate cancer.
Racial disparities are apparent in the management and outcomes for prostate cancer; however, disparities in compliance to quality measures for radiation therapy for prostate cancer have not been previously studied. The goal of this study was to characterize disparities in the compliance rates with quality measures. The investigators suggest that addressing disparities in access to providers that meet quality guidelines, and improving adherence to evidence-based processes of care may decrease racial/ethnic disparities in prostate cancer outcomes.
AHRQ-funded; HS019356; HS022640.
Citation: Lee DJ, Zhao Z, Huang LC .
Racial variation in receipt of quality radiation therapy for prostate cancer.
Cancer Causes Control 2018 Oct;29(10):895-99. doi: 10.1007/s10552-018-1065-5..
Keywords: Cancer: Prostate Cancer, Disparities, Quality Measures, Racial and Ethnic Minorities
Lee DJ, Barocas DA, Zhao Z
Contemporary prostate cancer radiation therapy in the United States: patterns of care and compliance with quality measures.
This study measured compliance with quality measures for radiation therapy treatment of prostate cancer. The Comparative Effectiveness Analysis of Surgery and Radiation Study enrolled men who were treated for localized prostate cancer from 2011 and 2012. Medical records were reviewed, and patients completed surveys. Researchers concluded that men who received external beam radiation therapy (EBRT) were treated more appropriately than those treated with brachytherapy (BT). White men were also more likely to receive appropriate treatment than African-American and other minorities.
AHRQ-funded; HS019356; HS022640.
Citation: Lee DJ, Barocas DA, Zhao Z .
Contemporary prostate cancer radiation therapy in the United States: patterns of care and compliance with quality measures.
Pract Radiat Oncol 2018 Sep-Oct;8(5):307-16. doi: 10.1016/j.prro.2018.04.009..
Keywords: Cancer, Cancer: Prostate Cancer, Comparative Effectiveness, Evidence-Based Practice, Guidelines, Patient-Centered Outcomes Research, Practice Patterns, Quality Measures
Modi PK, Kaufman SR, Borza T
Variation in prostate cancer treatment and spending among Medicare shared savings program accountable care organizations.
This study assessed whether the level of engagement in accountable care organizations (ACOs) by urologists affected rates of treatment, overtreatment, and spending. The investigators found that ACOs vary widely in treatment, potential overtreatment, and spending for prostate cancer. ACOs with stronger urologist engagement were less likely to treat men with a high risk of noncancer mortality, and this suggests that organizations that better engage specialists may be able to improve the value of specialty care.
AHRQ-funded; HS024728; HS025707; HS024525.
Citation: Modi PK, Kaufman SR, Borza T .
Variation in prostate cancer treatment and spending among Medicare shared savings program accountable care organizations.
Cancer 2018 Aug;124(16):3364-71. doi: 10.1002/cncr.31573..
Keywords: Cancer: Prostate Cancer, Healthcare Costs, Healthcare Utilization, Medicare
Tyson MD, Koyama T, Lee D
Effect of prostate cancer severity on functional outcomes after localized treatment: comparative effectiveness analysis of surgery and radiation study results.
The purpose of this study was to determine whether differences in predicted function over time between radical prostatectomy (RP) or external beam radiotherapy (EBRT) for localized cancer varied by risk group. Patient-reported, disease-specific function was measured using the Expanded Prostate Index Composite and predicted function was estimated using regression models, compared by disease risk. The study found that sexual function was similar between surgery and radiation for patients with high-risk disease, and the authors conclude that high-risk patients undergoing radiation therapy should be counseled that their sexual function may not be as good as low-risk patients also undergoing radiation.
AHRQ-funded; HS019356; HS022640.
Citation: Tyson MD, Koyama T, Lee D .
Effect of prostate cancer severity on functional outcomes after localized treatment: comparative effectiveness analysis of surgery and radiation study results.
Eur Urol 2018 Jul;74(1):26-33. doi: 10.1016/j.eururo.2018.02.012..
Keywords: Cancer: Prostate Cancer, Cancer, Comparative Effectiveness, Treatments, Surgery, Patient-Centered Outcomes Research, Outcomes, Evidence-Based Practice
Misra-Hebert AD, Hom G, Klein EA
Testing of a tool for prostate cancer screening discussions in primary care.
As prostate cancer (PCa) screening decisions often occur in outpatient primary care, a brief tool to help the PCa screening conversation in busy clinic settings is needed. This paper discusses a previously-created 9-item tool to aid (PCa) screening discussions. The study found that the brief conversation tool was well received in busy primary-care settings and improved patients' knowledge about the screening decision.
AHRQ-funded; HS024128.
Citation: Misra-Hebert AD, Hom G, Klein EA .
Testing of a tool for prostate cancer screening discussions in primary care.
Front Oncol 2018 Jun 28;8:238. doi: 10.3389/fonc.2018.00238..
Keywords: Cancer: Prostate Cancer, Decision Making, Patient-Centered Outcomes Research, Primary Care, Screening
Luckenbaugh AN, Holllenbeck BK, Kaufman SR
Impact of accountable care organizations on diagnostic testing for prostate cancer.
The researchers sought to determine if Accountable Care Organizations (ACOs) have the potential to accelerate the impact of prostate cancer screening recommendations. They concluded that the rate of PSA testing was not differentially affected by ACO participation. Conversely, there was an increase in the rate of prostate biopsy among patients of ACO-aligned physicians.
AHRQ-funded; HS024728; HS025707; HS024525.
Citation: Luckenbaugh AN, Holllenbeck BK, Kaufman SR .
Impact of accountable care organizations on diagnostic testing for prostate cancer.
Urology 2018 Jun;116:68-75. doi: 10.1016/j.urology.2018.01.056.
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Keywords: Cancer: Prostate Cancer, Health Services Research (HSR), Screening
Kistler CE, Vu M, Sutkowi-Hemstreet A
Exploring factors that might influence primary-care provider discussion of and recommendation for prostate and colon cancer screening.
This study sought to examine circumstances under which primary-care providers would discuss and recommend two types of cancer screening services across a spectrum of net benefit and other factors known to influence screening. While most providers' reported practice patterns aligned with net benefit, some providers would discuss and recommend low-value cancer screening, particularly when faced with a patient request.
AHRQ-funded; HS019468; HS021133.
Citation: Kistler CE, Vu M, Sutkowi-Hemstreet A .
Exploring factors that might influence primary-care provider discussion of and recommendation for prostate and colon cancer screening.
Int J Gen Med 2018 May 17;11:179-90. doi: 10.2147/ijgm.s153887..
Keywords: Cancer: Colorectal Cancer, Cancer: Prostate Cancer, Primary Care, Practice Patterns, Screening
Chhatre S, Jayadevappa R
Racial and ethnic disparities in substance use disorders and outcomes in elderly prostate cancer patients.
This study used Surveillance, Epidemiology, and End Results (SEER)-Medicare linked data to identify prevalence of substance use among patients with advanced-stage prostate cancer. There are racial and ethnic disparities between substance use and outcomes. A multidisciplinary coordinated care approach is recommended to address these disparities.
AHRQ-funded; HS024106.
Citation: Chhatre S, Jayadevappa R .
Racial and ethnic disparities in substance use disorders and outcomes in elderly prostate cancer patients.
J Ethn Subst Abuse 2018 Apr-Jun;17(2):135-49. doi: 10.1080/15332640.2016.1160019..
Keywords: Cancer: Prostate Cancer, Disparities, Elderly, Outcomes, Racial and Ethnic Minorities, Substance Abuse
Holmes-Rovner M, Srikanth A, Henry SG
Decision aid use during post-biopsy consultations for localized prostate cancer.
The purpose of this study was to characterize the content and communicative function of high-quality decision aids during diagnostic clinic visits for prostate cancer. Results showed that good decision aids, systematically provided to patients, appeared to function not to open up deliberations about how to balance benefits and harms of competing treatments, but rather to allow patients to ask narrow technical questions about recommended treatments.
AHRQ-funded; HS021764.
Citation: Holmes-Rovner M, Srikanth A, Henry SG .
Decision aid use during post-biopsy consultations for localized prostate cancer.
Health Expect 2018 Feb;21(1):279-87. doi: 10.1111/hex.12613..
Keywords: Cancer: Prostate Cancer, Decision Making, Evidence-Based Practice, Patient and Family Engagement, Patient-Centered Healthcare, Clinician-Patient Communication
Borza T, Kaufman SR, Yan P
Early effect of Medicare Shared Savings Program accountable care organization participation on prostate cancer care.
The purpose of this study was to understand the effect of Medicare Shared Savings Program accountable care organizations (ACOs) on prostate cancer care. The authors found that the treatment of prostate cancer and annual payments decreased significantly between 2010 and 2013, but ACO participation did not appear to impact these trends. Among men least likely to benefit, Medicare Shared Savings Program ACO alignment was associated with a significant decline in prostate cancer treatment.
AHRQ-funded; HS024728; HS024525.
Citation: Borza T, Kaufman SR, Yan P .
Early effect of Medicare Shared Savings Program accountable care organization participation on prostate cancer care.
Cancer 2018 Feb 1;124(3):563-70. doi: 10.1002/cncr.31081..
Keywords: Cancer: Prostate Cancer, Healthcare Costs, Medicare
Elstad EA, Sheridan SL, Lee JG
Have screening harms become newsworthy? News coverage of prostate and colorectal cancer screening since the 2008 USPSTF recommendation changes.
The researchers aimed to determine whether newspapers portrayed screening for prostate and colorectal cancers differently after the 2008 USPSTF recommendation changes. In US newspapers from 2005 to 2012, they found that benefits in prostate cancer screening articles and harms and benefits in colonoscopy articles did not change over time, but mentions of prostate cancer screening harms increased after 2008. They concluded that consumers, especially lay consumers, are receiving unbalanced information on cancer screening.
AHRQ-funded; HS021133; HS000032.
Citation: Elstad EA, Sheridan SL, Lee JG .
Have screening harms become newsworthy? News coverage of prostate and colorectal cancer screening since the 2008 USPSTF recommendation changes.
J Behav Med 2014 Dec;37(6):1242-51. doi: 10.1007/s10865-014-9572-7.
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Keywords: Cancer: Colorectal Cancer, Colonoscopy, Cancer: Prostate Cancer, Screening, U.S. Preventive Services Task Force (USPSTF)
Bhavsar NA, Bream JH, Meeker AK
A peripheral circulating TH1 cytokine profile is inversely associated with prostate cancer risk in CLUE II.
The authors evaluated the association between peripheral-cytokine concentrations and prostate cancer. They found that men with a prediagnostic circulating TH1 profile and higher IL6 may have a lower risk of prostate cancer, including aggressive disease. They concluded that identifying specific inflammatory cytokines associated with prostate cancer may lead to improved prevention and treatment strategies.
AHRQ-funded; HS019488.
Citation: Bhavsar NA, Bream JH, Meeker AK .
A peripheral circulating TH1 cytokine profile is inversely associated with prostate cancer risk in CLUE II.
Cancer Epidemiol Biomarkers Prev 2014 Nov;23(11):2561-7. doi: 10.1158/1055-9965.epi-14-0010.
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Keywords: Patient-Centered Outcomes Research, Cancer: Prostate Cancer, Risk
Rabin BA, Ellis JL, Steiner JF
Health-care utilization by prognosis profile in a managed care setting: using the Surveillance, Epidemiology and End Results Cancer Survival Calculator SEER*CSC.
The authors described health service utilization patterns of subgroups of prostate cancer and colorectal cancer (CRC) patients with different relative probabilities of dying of their cancer or other conditions. They found that although a new diagnosis of cancer increased utilization of cancer-related services for an extended time period, the timing of cancer diagnosis did not appear to affect other types of utilization.
AHRQ-funded; HS019520.
Citation: Rabin BA, Ellis JL, Steiner JF .
Health-care utilization by prognosis profile in a managed care setting: using the Surveillance, Epidemiology and End Results Cancer Survival Calculator SEER*CSC.
J Natl Cancer Inst Monogr 2014 Nov;2014(49):275-81. doi: 10.1093/jncimonographs/lgu023.
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Keywords: Cancer: Prostate Cancer, Cancer: Colorectal Cancer, Cancer, Healthcare Utilization, Mortality, Healthcare Delivery
Feuer EJ, Rabin BA, Zou Z
The Surveillance, Epidemiology, and End Results Cancer Survival Calculator SEER*CSC: validation in a managed care setting.
The researchers externally validate the nomograms for prostate and colorectal cancer using data from Kaiser Permanente Colorado. Their results indicated that the colorectal and prostate cancer nomograms are reliable tools for physicians and patients to use to obtain information on prognosis and assist in establishing priorities for both treatment of the cancer and other conditions, particularly when a patient is elderly and/or has significant comorbidities.
AHRQ-funded; HS019520.
Citation: Feuer EJ, Rabin BA, Zou Z .
The Surveillance, Epidemiology, and End Results Cancer Survival Calculator SEER*CSC: validation in a managed care setting.
J Natl Cancer Inst Monogr 2014 Nov;2014(49):265-74. doi: 10.1093/jncimonographs/lgu021.
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Keywords: Cancer: Colorectal Cancer, Cancer: Prostate Cancer, Cancer, Mortality
Merdan S, Womble PR, Miller DC
Toward better use of bone scans among men with early-stage prostate cancer.
This study evaluated the performance of published guidelines compared with that of current practice for radiographic staging of men with newly diagnosed prostate cancer. It found that, based on current practice patterns, more uniform application of existing guidelines would ensure that bone scans are performed for almost all men with bone metastases, while avoiding many negative imaging studies.
AHRQ-funded; HS018346
Citation: Merdan S, Womble PR, Miller DC .
Toward better use of bone scans among men with early-stage prostate cancer.
Urology. 2014 Oct;84(4):793-8. doi: 10.1016/j.urology.2014.06.010..
Keywords: Cancer: Prostate Cancer, Guidelines, Imaging
Goodwin JS, Jaramillo E, Yang L
Is anyone listening? Variation in PSA screening among providers for men 75+ before and after United States Preventive Services Task Force recommendations against it: a retrospective cohort study.
The authors assessed prostate specific antigen (PSA) screening by primary care physicians (PCPs) before and after the 2008 United States Preventive Services Task Force (USPSTF) recommendations. They found that the USPSTF recommendation did not increase consensus among PCPs regarding PSA screening of older men.
AHRQ-funded; HS022134.
Citation: Goodwin JS, Jaramillo E, Yang L .
Is anyone listening? Variation in PSA screening among providers for men 75+ before and after United States Preventive Services Task Force recommendations against it: a retrospective cohort study.
PLoS One 2014 Sep 10;9(9):e107352. doi: 10.1371/journal.pone.0107352.
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Keywords: Cancer: Prostate Cancer, Practice Patterns, Primary Care, Screening, U.S. Preventive Services Task Force (USPSTF)
Cobran EK, Wutoh AK, Lee E
Perceptions of prostate cancer fatalism and screening behavior between United States-born and Caribbean-born Black males.
The purpose of this study was to compare perceptions of prostate cancer (CaP) fatalism and predictors of CaP screening with Prostate Specific Antigen (PSA) testing between U.S.-born and Caribbean-born African-American males. In their study of 211 U.S.-born and Caribbean-born Black males between ages 39–75, the researchers found that nativity was not a significant predictor of CaP screening with PSA testing within the last year.
AHRQ-funded; HS011673.
Citation: Cobran EK, Wutoh AK, Lee E .
Perceptions of prostate cancer fatalism and screening behavior between United States-born and Caribbean-born Black males.
J Immigr Minor Health 2014 Jun;16(3):394-400. doi: 10.1007/s10903-013-9825-5..
Keywords: Cancer: Prostate Cancer, Screening, Racial and Ethnic Minorities, Racial and Ethnic Minorities, Cancer
Barbash GI, Friedman B, Glied SA
AHRQ Author: Barbash GI, Friedman B, Glied SA, Steiner CA
Factors associated with adoption of robotic surgical technology in US hospitals and relationship to radical prostatectomy procedure volume.
The authors aimed to identify the factors associated with hospitals' decisions to adopt robotic technology and the consequences of these decisions. They found that hospitals in areas where a higher proportion of other hospitals had already acquired a robot were more likely to acquire one, as were those with more than 300 beds and teaching hospitals. They also found a significant association between years with a robot and the change in the number of radical prostatectomies. They concluded that local area robot competition was associated with the rapid spread of robot technology in the United States.
AHRQ-authored.
Citation: Barbash GI, Friedman B, Glied SA .
Factors associated with adoption of robotic surgical technology in US hospitals and relationship to radical prostatectomy procedure volume.
Ann Surg 2014 Jan;259(1):1-6. doi: 10.1097/SLA.0b013e3182a5c8b8.
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Keywords: Hospitals, Cancer: Prostate Cancer, Surgery