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AHRQ Research Studies Date
Topics
- (-) Alcohol Use (13)
- Behavioral Health (2)
- Case Study (1)
- Community-Acquired Infections (1)
- Comparative Effectiveness (1)
- Data (1)
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- Substance Abuse (11)
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- Young Adults (1)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 13 of 13 Research Studies DisplayedShen NT, Salajegheh A, Brown RS
A call to standardize definitions, data collection, and outcome assessment to improve care in alcohol-related liver disease.
Alcohol-related liver disease (ALD) is highly prevalent and appears to be increasingly reported with worsening mortality; thus, optimizing care in this patient population is imperative. This requires a multidisciplinary, multifaceted approach that includes recognizing alcohol use disorder (AUD) and existing treatments for AUD. In this paper, the authors call for standardizing definitions, data collection, and outcome assessment to improve care in alcohol-related liver disease.
AHRQ-funded; HS000066.
Citation: Shen NT, Salajegheh A, Brown RS .
A call to standardize definitions, data collection, and outcome assessment to improve care in alcohol-related liver disease.
Hepatology 2019 Sep;70(3):1038-44. doi: 10.1002/hep.30587..
Keywords: Data, Alcohol Use, Outcomes
Ibrahim N, Alameddine M, Brennan J
New onset alcohol use disorder following bariatric surgery.
Researchers sought to characterize the patients and incidence of alcohol use disorder (AUD) following sleeve gastrectomy (SG) compared to Roux-en-Y gastric bypass (RYGB). They found that the prevalence of alcohol use disorder in patients undergoing SG and RYGB was similar pre- and postoperatively, with the majority of patients developing AUD following their second postoperative year. The authors recommended understanding the timing and incidence of AUD in order to provide appropriate counseling and treatment.
AHRQ-funded; HS023621; HS024403.
Citation: Ibrahim N, Alameddine M, Brennan J .
New onset alcohol use disorder following bariatric surgery.
Surg Endosc 2019 Aug;33(8):2521-30. doi: 10.1007/s00464-018-6545-x..
Keywords: Alcohol Use, Behavioral Health, Obesity, Obesity: Weight Management, Substance Abuse, Surgery
Mabry-Hernandez I, Scoulios N
AHRQ Author: Mabry-Hernandez I
Screening and behavioral counseling interventions to reduce unhealthy alcohol use in adolescents and adults.
This case study concerns a 20-year-old male university student with a history of exercise-induced asthma presenting for his yearly physical. He expresses that he occasionally misses classes in the morning because he is tired.
AHRQ-authored.
Citation: Mabry-Hernandez I, Scoulios N .
Screening and behavioral counseling interventions to reduce unhealthy alcohol use in adolescents and adults.
Am Fam Physician 2019 Jun 15;99(12):771-72..
Keywords: U.S. Preventive Services Task Force (USPSTF), Alcohol Use, Substance Abuse, Screening, Prevention, Primary Care, Case Study
Gupta NM, Lindenauer PK, Yu PC
Association between alcohol use disorders and outcomes of patients hospitalized with community-acquired pneumonia.
The purpose of this study was to compare the causes, treatment, and outcomes of pneumonia in patients with and without alcohol use disorder (AUD). Results suggest that, compared with hospitalized patients with community-acquired pneumonia but without AUD, those with AUD less often harbor resistant organisms. The authors conclude that higher age-adjusted risk of death among patients with AUD appears to be largely attributable to differences in comorbidities, whereas greater use of health care resources may be attributable to alcohol withdrawal.
AHRQ-funded; HS024277; HS025026.
Citation: Gupta NM, Lindenauer PK, Yu PC .
Association between alcohol use disorders and outcomes of patients hospitalized with community-acquired pneumonia.
JAMA Netw Open 2019 Jun 5;2(6):e195172. doi: 10.1001/jamanetworkopen.2019.5172..
Keywords: Alcohol Use, Community-Acquired Infections, Hospitalization, Outcomes, Pneumonia, Substance Abuse
Kazemi DM, Borsari B, Levine MJ
Real-time demonstration of a mHealth app designed to reduce college students hazardous drinking.
The authors developed a smartphone application (SmarTrek) that targets college students and aims to reduce risky alcohol use. They found that the majority of participants agreed that SmarTrek was easy to use and that the information provided was useful and had a positive effect on decreasing their drinking.
AHRQ-funded; HS023875.
Citation: Kazemi DM, Borsari B, Levine MJ .
Real-time demonstration of a mHealth app designed to reduce college students hazardous drinking.
Psychol Serv 2019 May;16(2):255-59. doi: 10.1037/ser0000310..
Keywords: Alcohol Use, Behavioral Health, Lifestyle Changes, Health Information Technology (HIT), Substance Abuse, Telehealth, Young Adults
Shen NT, Londono C, Gold S
Systematic review with meta-analysis on transplantation for alcohol-related liver disease: very low evidence of improved outcomes.
Under the hypothesis that, while liver transplantation for patients with alcohol-related liver disease (ALD) may improve mortality and relapse, findings will be limited by pre-specified causes of heterogeneity, researchers conducted a systematic review. Data from 10 studies comparing use of liver transplant in ALD to no-transplant was analyzed. Primary outcome of both was short- and long-term mortality and relapse. The results of the review indicate that liver transplantation for ALD patients suggests reduced mortality and relapse in heterogeneous, institution-specific populations. The authors note that, to understand efficacy of transplanting ALD, their research approach must change.
AHRQ-funded; HS000066.
Citation: Shen NT, Londono C, Gold S .
Systematic review with meta-analysis on transplantation for alcohol-related liver disease: very low evidence of improved outcomes.
World J Gastroenterol 2019 Apr 7;25(13):1628-39. doi: 10.3748/wjg.v25.i13.1628..
Keywords: Alcohol Use, Evidence-Based Practice, Mortality, Outcomes, Patient-Centered Outcomes Research, Surgery, Transplantation
Shafer PR, Borsky A, Ngo-Metzger Q
AHRQ Author: Shafer PR, Borsky A, Ngo-Metzger Q, Miller T, Meyers D
The practice gap: national estimates of screening and counseling for alcohol, tobacco, and obesity.
The authors of this study estimated screening and counseling rates for tobacco and alcohol use, and obesity by using a nationally representative sample of adults aged 35 years and older. Receipt of the recommended level of services ranged from nearly two-thirds for obesity and tobacco use to less than half for alcohol misuse. The authors conclude that care delivery shows significant room for improvement, but primary care practices may need additional resources to raise their screening and counseling rates.
AHRQ-authored.
Citation: Shafer PR, Borsky A, Ngo-Metzger Q .
The practice gap: national estimates of screening and counseling for alcohol, tobacco, and obesity.
Ann Fam Med 2019 Mar;17(2):161-63. doi: 10.1370/afm.2363..
Keywords: Alcohol Use, Lifestyle Changes, Obesity, Prevention, Primary Care, Screening, Substance Abuse, Tobacco Use
Lapham GT, Rubinsky AD, Williams EC
Decreasing sensitivity of clinical alcohol screening with the AUDIT-C after repeated negative screens in VA clinics.
The purpose of this study was to evaluate the performance of repeat annual clinical alcohol screening in 4 samples of VA outpatients with 1–4 prior consecutive negative annual screens. It found that among patients with repeated negative clinical alcohol screens, the proportion who subsequently screened positive a year later was low and decreased as patients had more prior negative screens.
AHRQ-funded; HS022800.
Citation: Lapham GT, Rubinsky AD, Williams EC .
Decreasing sensitivity of clinical alcohol screening with the AUDIT-C after repeated negative screens in VA clinics.
Drug Alcohol Depend 2014 Sep 1;142:209-15. doi: 10.1016/j.drugalcdep.2014.06.017..
Keywords: Screening, Alcohol Use, Substance Abuse
Jonas DE, Amick HR, Feltner C
Genetic polymorphisms and response to medications for alcohol use disorders: a systematic review and meta-analysis.
This review assessed whether response to medications for alcohol use disorders varies by genotype. It found that estimates of effect for return to heavy drinking suggest it is possible that patients with at least one G allele of A118G polymorphism of OPRM1 might be more likely to respond to naltrexone.
290201200008I; 29032002T
Citation: Jonas DE, Amick HR, Feltner C .
Genetic polymorphisms and response to medications for alcohol use disorders: a systematic review and meta-analysis.
Pharmacogenomics 2014 Sep;15(13):1687-700. doi: 10.2217/pgs.14.121..
Keywords: Medication, Alcohol Use, Substance Abuse, Genetics
Jonas DE, Amick HR, Feltner C
Genetic polymorphisms and response to medications for alcohol use disorders: a systematic review and meta-analysis.
This review assessed whether response to medications for alcohol use disorders varies by genotype. It found that estimates of effect for return to heavy drinking suggest it is possible that patients with at least one G allele of A118G polymorphism of OPRM1 might be more likely to respond to naltrexone.
290201200008I; 29032002T
Citation: Jonas DE, Amick HR, Feltner C .
Genetic polymorphisms and response to medications for alcohol use disorders: a systematic review and meta-analysis.
Pharmacogenomics 2014 Sep;15(13):1687-700. doi: 10.2217/pgs.14.121..
Keywords: Medication, Alcohol Use, Substance Abuse, Genetics
Hartung DM, McCarty D, Fu R
Extended-release naltrexone for alcohol and opioid dependence: a meta-analysis of healthcare utilization studies.
The authors evaluated cost and utilization outcomes between extended-release naltrexone (XR-NTX) and other pharmacotherapies for treatment of alcohol and opioid dependence. They found that alcohol dependent XR-NTX patients had longer medication refill persistence versus acamprosate and oral naltrexone, with healthcare utilization and costs being generally lower or as low for XR-NTX-treated patients relative to other alcohol dependence agents. Opioid dependent XR-NTX patients had lower inpatient substance abuse-related utilization versus other agents and $8170 lower total cost versus methadone.
AHRQ-funded; HS019456.
Citation: Hartung DM, McCarty D, Fu R .
Extended-release naltrexone for alcohol and opioid dependence: a meta-analysis of healthcare utilization studies.
J Subst Abuse Treat 2014 Aug;47(2):113-21. doi: 10.1016/j.jsat.2014.03.007.
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Keywords: Alcohol Use, Comparative Effectiveness, Medication, Opioids, Substance Abuse
Cochran G, Field C, Caetano R
Injury-related consequences of alcohol misuse among injured patients who received screening and brief intervention for alcohol: a latent class analysis.
This study identifies latent classes of intervention recipients based on injury-related consequences and risks of alcohol misuse and then determines which profiles experienced the greatest improvements in drinking. It found that the patients who reported the greatest improvements in drinking following discharge were those characterized by multiple alcohol-related risks and those characterized by a history of alcohol-related accidents and injuries.
AHRQ-funded; HS021394.
Citation: Cochran G, Field C, Caetano R .
Injury-related consequences of alcohol misuse among injured patients who received screening and brief intervention for alcohol: a latent class analysis.
Subst Abus 2014;35(2):153-62. doi: 10.1080/08897077.2013.820679..
Keywords: Alcohol Use, Substance Abuse, Risk
Quanbeck A, Chih MY, Isham A
Mobile delivery of treatment for alcohol use disorders: A review of the literature.
This article explores questions about mobile applications intended for patients dealing with alcohol-use disorders (AUD) s including: What mHealth applications to treat AUDs exist that have been evaluated in the peer-reviewed literature and how can they be categorized? What are common features of these applications? How effective are currently commercially available mHealth applications for AUDs? What are the characteristics, benefits, and limitations of mHealth applications for AUDs?
AHRQ-funded; HS01991702.
Citation: Quanbeck A, Chih MY, Isham A .
Mobile delivery of treatment for alcohol use disorders: A review of the literature.
Alcohol Res 2014;36(1):111-22..
Keywords: Alcohol Use, Health Information Technology (HIT), Substance Abuse, Telehealth