National Healthcare Quality and Disparities Report
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AHRQ Research Studies Date
Topics
- Access to Care (1)
- Adverse Drug Events (ADE) (2)
- Adverse Events (6)
- Antibiotics (2)
- Breast Feeding (1)
- Cardiovascular Conditions (1)
- Care Coordination (1)
- Caregiving (3)
- Care Management (1)
- Case Study (1)
- Children/Adolescents (6)
- Clinical Decision Support (CDS) (1)
- Communication (1)
- Comparative Effectiveness (1)
- Comprehensive Unit-based Safety Program (CUSP) (1)
- Critical Care (2)
- Decision Making (3)
- Depression (1)
- Diagnostic Safety and Quality (3)
- Disabilities (1)
- Education: Continuing Medical Education (1)
- Electronic Prescribing (E-Prescribing) (1)
- Emergency Department (2)
- Emergency Preparedness (1)
- Evidence-Based Practice (4)
- Eye Disease and Health (1)
- Family Health and History (2)
- Guidelines (3)
- Healthcare-Associated Infections (HAIs) (1)
- Healthcare Cost and Utilization Project (HCUP) (2)
- Healthcare Costs (2)
- Health Information Technology (HIT) (2)
- Health Insurance (2)
- Health Services Research (HSR) (1)
- Heart Disease and Health (1)
- Hospital Discharge (1)
- Hospitalization (4)
- Hospital Readmissions (2)
- Hospitals (4)
- Infectious Diseases (4)
- Injuries and Wounds (1)
- Inpatient Care (2)
- Intensive Care Unit (ICU) (7)
- Kidney Disease and Health (2)
- Labor and Delivery (3)
- Lifestyle Changes (1)
- Maternal Care (4)
- Medicaid (3)
- Medical Errors (1)
- Medication (5)
- Medication: Safety (2)
- Mortality (3)
- Neonatal Intensive Care Unit (NICU) (5)
- Neurological Disorders (1)
- (-) Newborns/Infants (41)
- Nutrition (3)
- Outcomes (10)
- Patient-Centered Outcomes Research (4)
- Patient and Family Engagement (2)
- Patient Safety (10)
- Pregnancy (7)
- Pressure Ulcers (1)
- Prevention (4)
- Provider (2)
- Provider: Clinician (1)
- Provider: Health Personnel (1)
- Provider: Nurse (1)
- Provider: Physician (2)
- Provider Performance (1)
- Quality Improvement (1)
- Quality Indicators (QIs) (1)
- Quality Measures (1)
- Quality of Care (3)
- Quality of Life (1)
- Registries (2)
- Respiratory Conditions (2)
- Risk (2)
- Rural Health (1)
- Screening (2)
- Simulation (2)
- Skin Conditions (1)
- Social Determinants of Health (1)
- Surgery (2)
- Surveys on Patient Safety Culture (1)
- Teams (1)
- TeamSTEPPS (1)
- Training (2)
- Transitions of Care (1)
- U.S. Preventive Services Task Force (USPSTF) (1)
- Urinary Tract Infection (UTI) (2)
- Women (4)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 25 of 41 Research Studies DisplayedGreenhawt M, Shaker M
Determining levers of cost-effectiveness for screening infants at high risk for peanut sensitization before early peanut introduction.
The authors sought to identify scenarios in which current early peanut introduction guidelines would be cost-effective. They found that the current screening approach to early peanut introduction could be cost-effective at a particular health utility for an in-clinic reaction, skin prick test sensitivity and specificity, and high baseline peanut allergy prevalence among high-risk infants. However, such conditions are unlikely to be plausible to achieve realistically. They recommend further research to define the health state utility associated with reaction location.
AHRQ-funded; HS024599.
Citation: Greenhawt M, Shaker M .
Determining levers of cost-effectiveness for screening infants at high risk for peanut sensitization before early peanut introduction.
JAMA Netw Open 2019 Dec 2;2(12):e1918041. doi: 10.1001/jamanetworkopen.2019.18041..
Keywords: Patient-Centered Outcomes Research, Newborns/Infants, Children/Adolescents, Respiratory Conditions, Skin Conditions, Screening, Healthcare Costs, Evidence-Based Practice, Guidelines
Stoops C, Stone S, Evans E
Baby NINJA (Nephrotoxic Injury Negated by Just-in-Time Action): reduction of nephrotoxic medication-associated acute kidney injury in the neonatal intensive care unit.
The purpose of this study was to test if acute kidney injury (AKI) is preventable in patients in the neonatal intensive care unit and if infants at high-risk of nephrotoxic medication-induced AKI can be identified using a systematic surveillance program previously used in the pediatric non-intensive care unit setting. The authors concluded that a systematic surveillance program to identify high-risk infants can prevent nephrotoxic-induced AKI and has the potential to prevent short and long-term consequences of AKI in critically ill infants.
AHRQ-funded; HS023763.
Citation: Stoops C, Stone S, Evans E .
Baby NINJA (Nephrotoxic Injury Negated by Just-in-Time Action): reduction of nephrotoxic medication-associated acute kidney injury in the neonatal intensive care unit.
J Pediatr 2019 Dec;215:223-28.e6. doi: 10.1016/j.jpeds.2019.08.046..
Keywords: Newborns/Infants, Medication, Medication: Safety, Patient Safety, Kidney Disease and Health, Intensive Care Unit (ICU), Critical Care, Quality Improvement, Quality of Care, Prevention, Adverse Drug Events (ADE), Adverse Events
Fleischer E, Neuman MI, Wang ME
Cerebrospinal fluid profiles of infants </=60 days of age with bacterial meningitis.
This study’s aim was to describe the cerebrospinal fluid (CSF) profiles in infants 60 days old or younger with bacterial meningitis and characteristics of infants with bacterial meningitis who do not have CSF abnormalities. Infants with culture-positive bacterial meningitis were evaluated in emergency departments of 11 children’s hospitals between 2011 and 2016. Clinical and laboratory data were abstracted from their medical records. Sensitivity of a CFS Gram-stain and corrected CSF pleocytosis was calculated for bacterial meningitis. Most infants 60 days or younger with bacterial meningitis have CSF pleocytosis or a positive Gram-stain result. Bacterial meningitis was unlikely in infants with no CSF pleocytosis and a negative Gram-stain result.
AHRQ-funded; HS026006.
Citation: Fleischer E, Neuman MI, Wang ME .
Cerebrospinal fluid profiles of infants </=60 days of age with bacterial meningitis.
Hosp Pediatr 2019 Dec;9(12):979-82. doi: 10.1542/hpeds.2019-0202..
Keywords: Newborns/Infants, Children/Adolescents, Infectious Diseases
Shafer G, Singh H, Suresh G
Diagnostic errors in the neonatal intensive care unit: state of the science and new directions.
In this narrative review, the authors discuss how the concept of diagnostic errors framed as missed opportunities can be applied to the non-linear nature of diagnosis in a critical care environment such as the NICU. They then explore how the etiology of an error in diagnosis can be related to both individual cognitive factors as well as organizational and systemic factors - all of which often contribute to the error.
AHRQ-funded; HS022087.
Citation: Shafer G, Singh H, Suresh G .
Diagnostic errors in the neonatal intensive care unit: state of the science and new directions.
Semin Perinatol 2019 Dec;43(8):151175. doi: 10.1053/j.semperi.2019.08.004..
Keywords: Newborns/Infants, Diagnostic Safety and Quality, Neonatal Intensive Care Unit (NICU), Medical Errors, Adverse Events, Patient Safety
Williams CN, Eriksson CO, Kirby A
Hospital mortality and functional outcomes in pediatric neurocritical care.
Pediatric neurocritical care (PNCC) outcomes research is scarce. In this study, the investigators aimed to expand knowledge about outcomes in PNCC by evaluating death and changes in Functional Status Scale (FSS) from baseline among PNCC diagnoses. The investigators concluded that PNCC patients had high rates of death and new disability at discharge, varying significantly between PNCC diagnoses. Multiple domains of disability were affected, underscoring the ongoing multidisciplinary health care needs of survivors.
AHRQ-funded; HS022981.
Citation: Williams CN, Eriksson CO, Kirby A .
Hospital mortality and functional outcomes in pediatric neurocritical care.
Hosp Pediatr 2019 Dec;9(12):958-66. doi: 10.1542/hpeds.2019-0173..
Keywords: Children/Adolescents, Newborns/Infants, Intensive Care Unit (ICU), Critical Care, Neurological Disorders, Mortality, Hospitals, Inpatient Care, Outcomes, Patient-Centered Outcomes Research
Cruz AT, Nigrovic LE, Xie J
Predictors of invasive herpes simplex virus infection in young infants.
This study’s objective was to identify independent predictors of invasive herpes simplex virus (HSV) infection in infants aged 60 days or less. This 23-center nested case-control study matched 149 infants with HSV to 1340 controls. All were 60 days or less old and had cerebrospinal fluid obtained within 24 hours of presentation or had HSV detected. Of the 149 infants with HSV, 90 had invasive and 59 had skin, eyes, and mouth disease. Predictors independently associated with invasive HSV included younger age (<28 days), prematurity, seizure at home, ill appearance, abnormal triage temperature, vesicular rash, thrombocytopenia, and cerebrospinal fluid pleocytosis. Infants with invasive HSV had a higher median risk score than those without invasive HSV.
AHRQ-funded; HS026006; HS025138.
Citation: Cruz AT, Nigrovic LE, Xie J .
Predictors of invasive herpes simplex virus infection in young infants.
Pediatrics 2021 Sep;148(3). doi: 10.1542/peds.2021-050052..
Keywords: Newborns/Infants, Infectious Diseases, Risk
Adelman JS, Applebaum JR, Southern WN
Risk of wrong-patient orders among multiple vs singleton births in the neonatal intensive care units of 2 integrated health care systems.
Researchers assessed the risk of wrong-patient orders among multiple-birth infants and singletons receiving care in the NICU and examined the proportion of wrong-patient orders between multiple-birth infants and siblings (intrafamilial errors) and between multiple-birth infants and nonsiblings (extrafamilial errors). They found that multiple-birth status in the NICU is associated with significantly increased risk of wrong-patient orders compared with singleton-birth status. Strategies to reduce this risk include using given names at birth, changing from temporary to given names when available, and encouraging parents to select names for multiple births before they are born when acceptable to families.
AHRQ-funded; HS024538.
Citation: Adelman JS, Applebaum JR, Southern WN .
Risk of wrong-patient orders among multiple vs singleton births in the neonatal intensive care units of 2 integrated health care systems.
JAMA Pediatr 2019 Oct 10;173(10):979-85. doi: 10.1001/jamapediatrics.2019.2733..
Keywords: Newborns/Infants, Intensive Care Unit (ICU), Adverse Drug Events (ADE), Adverse Events, Medication: Safety, Medication, Patient Safety, Electronic Prescribing (E-Prescribing), Health Information Technology (HIT)
Vemulakonda VM, Hamer MK, Kempe A
Surgical decision-making in infants with suspected UPJ obstruction: stakeholder perspectives.
Although there are significant demographic and clinical variations in treatment decisions for infants with high-grade hydronephrosis concerning for ureteropelvic junction obstruction (UPJO), there has been little research on the roles of parents and surgeons in the surgical decision-making (DM) process. The purpose of this study was to understand parents' and surgeons' perceived roles in the surgical DM process for infants with high-grade hydronephrosis.
AHRQ-funded; HS024597.
Citation: Vemulakonda VM, Hamer MK, Kempe A .
Surgical decision-making in infants with suspected UPJ obstruction: stakeholder perspectives.
J Pediatr Urol 2019 Oct;15(5):469.e1-69.e9. doi: 10.1016/j.jpurol.2019.05.027..
Keywords: Newborns/Infants, Decision Making, Surgery, Kidney Disease and Health, Caregiving, Provider: Physician, Provider, Patient and Family Engagement
Klawetter S, Neu M, Roybal KL S, Neu M, Roybal KL
Mothering in the NICU: a qualitative exploration of maternal engagement.
This qualitative study reflected a transdisciplinary research partnership between social work, nursing, and neonatology. Maternal experiences in the NICU, from the perspectives of mothers of preterm infants hospitalized in two NICUs, are collected. Results support an ecological systems framework to understanding barriers and facilitators to maternal engagement in the NICU and the utilization of a trauma-informed health care approach in NICU settings.
AHRQ-funded; HS026370.
Citation: Klawetter S, Neu M, Roybal KL S, Neu M, Roybal KL .
Mothering in the NICU: a qualitative exploration of maternal engagement.
Soc Work Health Care 2019 Sep;58(8):746-63. doi: 10.1080/00981389.2019.1629152..
Keywords: Newborns/Infants, Intensive Care Unit (ICU), Patient and Family Engagement
Desai S, Aronson PL, Shabanova V
Parenteral antibiotic therapy duration in young infants with bacteremic urinary tract infections.
This study compared rates of recurring bacteremic urinary tract infections (UTIs) among hospitalized infants who received parenteral antibiotics 7 days or less compared with infants who received long-term treatment defined as greater than 7 days. Among 115 infants with bactermic UTI, half received short-course parenteral antibiotics and no difference in 30-day UTI recurrence was found.
AHRQ-funded; HS026006.
Citation: Desai S, Aronson PL, Shabanova V .
Parenteral antibiotic therapy duration in young infants with bacteremic urinary tract infections.
Pediatrics 2019 Sep;144(3). doi: 10.1542/peds.2018-3844..
Keywords: Newborns/Infants, Antibiotics, Urinary Tract Infection (UTI), Medication, Inpatient Care, Hospitalization, Outcomes, Comparative Effectiveness, Patient-Centered Outcomes Research, Evidence-Based Practice
Ferguson MC, O'Shea KJ, Hammer LD
The impact of following solid food feeding guides on BMI among infants: a simulation study.
The objective of this study was to determine the impact of following different feeding guidelines on weight trajectories of infants. The study team developed a computational simulation model to capture feeding behaviors, activity levels, metabolism, and body size of infants from 6 months to 1 year old; daily food intake of virtual infants was based on feeding recommendations and translated to changes in body weight. Results identified situations in which infants could reach unhealthy weights, even while following complementary feeding guidelines, suggesting that current recommended portion sizes should be tightened.
AHRQ-funded; HS023317.
Citation: Ferguson MC, O'Shea KJ, Hammer LD .
The impact of following solid food feeding guides on BMI among infants: a simulation study.
Am J Prev Med 2019 Sep;57(3):355-64. doi: 10.1016/j.amepre.2019.04.011..
Keywords: Newborns/Infants, Nutrition, Guidelines
Knox CA, Hampp C, Palmsten K
Validation of mother-infant linkage using Medicaid Case ID variable within the Medicaid Analytic eXtract (MAX) database.
The authors established and validated an algorithm within the Medicaid Analytic eXtract (MAX) that links mothers to infants and to identify factors influencing successful mother-infant linkage. They found that their algorithm can correctly link liveborn infants to their mothers, with linkage performance being associated with certain characteristics that may affect representativeness of successfully linked pairs.
AHRQ-funded; HS022384.
Citation: Knox CA, Hampp C, Palmsten K .
Validation of mother-infant linkage using Medicaid Case ID variable within the Medicaid Analytic eXtract (MAX) database.
Pharmacoepidemiol Drug Saf 2019 Sep;28(9):1222-30. doi: 10.1002/pds.4843..
Keywords: Caregiving, Medicaid, Newborns/Infants, Patient Safety, Pregnancy
Aronson PL, Cruz AT, Freedman SB
Association of herpes simplex virus testing with hospital length of stay for infants </=60 days of age undergoing evaluation for meningitis.
The objective of this study was to examine the association of cerebrospinal fluid herpes simplex virus polymerase chain reaction (CSF HSV PCR) testing with length of stay in a 20-center retrospective cohort of hospitalized infants aged </=60 days undergoing evaluation for meningitis after adjustment for patient-level factors and clustering by center. The investigators found that of 20,496 eligible infants, 7,399 (36.1%) had a CSF HSV PCR test performed, and 46 (0.6% of those tested) had a positive test.
AHRQ-funded; HS026006.
Citation: Aronson PL, Cruz AT, Freedman SB .
Association of herpes simplex virus testing with hospital length of stay for infants </=60 days of age undergoing evaluation for meningitis.
J Hosp Med 2019 Aug;14(8):492-95. doi: 10.12788/jhm.3202..
Keywords: Diagnostic Safety and Quality, Infectious Diseases, Newborns/Infants
Gephart SM, Quinn MC
Relationship of necrotizing enterocolitis rates to adoption of prevention practices in US neonatal intensive care units.
Applying quality improvement methods has reduced necrotizing enterocolitis (NEC) in some neonatal intensive care units (NICUs) by 40% to 90%. This study was conducted to (1) examine relationships between adoption of prevention practices using the NEC-Zero adherence score and NEC rates, and (2) describe implementation strategies NICUs use to prevent NEC. The investigators concluded that broader use of evidence-based implementation strategies could bolster delivery of NEC prevention practices. The indicated that maternal lactation support is paramount.
AHRQ-funded; HS022908.
Citation: Gephart SM, Quinn MC .
Relationship of necrotizing enterocolitis rates to adoption of prevention practices in US neonatal intensive care units.
Adv Neonatal Care 2019 Aug;19(4):321-32. doi: 10.1097/anc.0000000000000592..
Keywords: Newborns/Infants, Neonatal Intensive Care Unit (NICU), Intensive Care Unit (ICU), Prevention
Wang HH, Kurtz M, Logvinenko T
Why does prevention of recurrent urinary tract infection not result in less renal scarring? A deeper dive into the RIVUR trial.
The RIVUR (Randomized Intervention for Children with Vesicoureteral Reflux) trial reported that antibiotic prophylaxis reduced recurrent urinary tract infection but antibiotic prophylaxis was not associated with decreased new renal scarring. However, the original reports did not assess the relationship among recurrent urinary tract infection, new renal scarring and antibiotic prophylaxis in detail. Therefore, this study investigated the relationship among these issues.
AHRQ-funded; HS000063.
Citation: Wang HH, Kurtz M, Logvinenko T .
Why does prevention of recurrent urinary tract infection not result in less renal scarring? A deeper dive into the RIVUR trial.
J Urol 2019 Aug;202(2):400-05. doi: 10.1097/ju.0000000000000292..
Keywords: Newborns/Infants, Urinary Tract Infection (UTI), Antibiotics, Medication, Prevention
Aronson PL, Schaeffer P, Fraenkel L
Physicians' and nurses' perspectives on the decision to perform lumbar punctures on febrile infants </=8 weeks old.
This paper discusses the reasons for wide variation in the decision to perform lumbar punctures (LPs) in febrile infants 8 weeks or less. Semi-structured interviews were conducted with 15 pediatric and general emergency medicine physicians and 8 pediatric emergency medicine nurses at an urban, academic medical center. Five themes emerged from the interviews that included: age of the infant, the physician’s clinical experience, physician’s use of research findings, the physician’s values, and the role of the primary care pediatrician.
AHRQ-funded; HS026006.
Citation: Aronson PL, Schaeffer P, Fraenkel L .
Physicians' and nurses' perspectives on the decision to perform lumbar punctures on febrile infants </=8 weeks old.
Hosp Pediatr 2019 Jun;9(6):405-14. doi: 10.1542/hpeds.2019-0002..
Keywords: Newborns/Infants, Decision Making, Provider: Physician, Provider: Nurse, Provider: Clinician, Provider, Emergency Department, Diagnostic Safety and Quality
Campbell KH, Illuzzi JL, Lee HC
Optimal maternal and neonatal outcomes and associated hospital characteristics.
The goal of this study was to examine hospital variation in both maternal and neonatal morbidities and to identify institutional characteristics associated with hospital performance in a combined measure of maternal and neonatal outcomes. The authors found that hospitals with low maternal morbidity rates may not have low neonatal morbidity rates and vice versa, highlighting the importance of assessing joint maternal-newborn outcomes in order to fully characterize a hospital's obstetrical performance.
AHRQ-funded; HS023801.
Citation: Campbell KH, Illuzzi JL, Lee HC .
Optimal maternal and neonatal outcomes and associated hospital characteristics.
Birth 2019 Jun;46(2):289-99. doi: 10.1111/birt.12400.
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Keywords: Hospitals, Newborns/Infants, Outcomes, Pregnancy, Provider Performance, Quality of Care, Women
Ozawa Y, Ades A, Foglia EE
Premedication with neuromuscular blockade and sedation during neonatal intubation is associated with fewer adverse events.
This study assessed the impact of using sedation with neuromuscular blockade in non-emergency tracheal intubation of neonates. The retrospective cohort was from infants in neonatal intensive care units (NICUs) participating the National Emergency Airway Registry for Neonates from 2014 to 2017. There was less adverse events associated with use of the neuromuscular blockade premedication.
AHRQ-funded; HS024511.
Citation: Ozawa Y, Ades A, Foglia EE .
Premedication with neuromuscular blockade and sedation during neonatal intubation is associated with fewer adverse events.
J Perinatol 2019 Jun;39(6):848-56. doi: 10.1038/s41372-019-0367-0..
Keywords: Adverse Events, Medication, Newborns/Infants, Outcomes, Patient Safety, Registries
Vanderlaan J, Rochat R, Williams B
Associations between hospital maternal service level and delivery outcomes.
This study explored the associations between delivery hospital self-reported level of maternal service, as defined by the American Hospital Association, and both maternal and neonatal outcomes among women at high maternal risk, as defined by the Obstetric Comorbidity Index. The investigators concluded that for the group of pregnant women in need of maternal transfer, delivery hospital self-reported level of maternal care was not associated with the odds of poor maternal or neonatal outcomes.
AHRQ-funded; HS024655.
Citation: Vanderlaan J, Rochat R, Williams B .
Associations between hospital maternal service level and delivery outcomes.
Womens Health Issues 2019 May - Jun;29(3):252-58. doi: 10.1016/j.whi.2019.02.004..
Keywords: Maternal Care, Labor and Delivery, Pregnancy, Women, Outcomes, Hospitals, Quality of Care, Newborns/Infants, Mortality
Hoch JM, Fatusin O, Yenokyan G
Feeding methods for infants with single ventricle physiology are associated with length of stay during stage 2 surgery hospitalization.
The purpose of this paper was to identify types of feeding methods following stage 2 palliation and their influence on length of stay. Results showed that feeding methods established at admission for stage 2 palliation are not likely to change by discharge, and that length of stay is more likely to be impacted by tube feeding and intubation history than by age or weight-for-age z score at admission. Recommendations included a better understanding for selection of feeding methods and their impact on patient outcomes in order to develop evidence-based guidelines to decrease variability in clinical practice patterns and to provide appropriate counseling to caregivers.
AHRQ-funded; HS021114.
Citation: Hoch JM, Fatusin O, Yenokyan G .
Feeding methods for infants with single ventricle physiology are associated with length of stay during stage 2 surgery hospitalization.
Congenit Heart Dis 2019 May;14(3):438-45. doi: 10.1111/chd.12742.
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Keywords: Nutrition, Newborns/Infants, Children/Adolescents, Hospitalization, Surgery, Heart Disease and Health, Cardiovascular Conditions, Evidence-Based Practice, Patient-Centered Outcomes Research
Patel SM, Spees L, Smieja M
Patel SM, Spees L, Smieja M, Luinstra K, Steenhoff AP, Feemster KA, Arscott-Mills T, et al. Predictors of poor outcomes among infants with respiratory syncytial virus-associated acute lower respiratory infection in Botswana.
This article examined predictors of poor outcomes among infants with respiratory syncytial virus-associated acute lower respiratory infection in Botswana. Among children 1-23 months of age with respiratory syncytial virus-associated acute lower respiratory infection in Botswana, young age (<6 months), household use of wood as a cooking fuel, moderate or severe malnutrition and oxygen saturation <90% on room air were independent predictors of clinical nonresponse at 48 hours.
AHRQ-funded; HS000032.
Citation: Patel SM, Spees L, Smieja M .
Patel SM, Spees L, Smieja M, Luinstra K, Steenhoff AP, Feemster KA, Arscott-Mills T, et al. Predictors of poor outcomes among infants with respiratory syncytial virus-associated acute lower respiratory infection in Botswana.
Pediatr Infect Dis J 2019 May;38(5):525-27. doi: 10.1097/inf.0000000000002168..
Keywords: Newborns/Infants, Respiratory Conditions, Outcomes
Lapcharoensap W, Cong A, Sherman J
Safety and ergonomic challenges of ventilating a premature infant during delayed cord clamping.
This study discussed the reasons that delayed cord clamping (DCC) for term and preterm infants is endorsed by multiple medical organizations. It has been shown to reduce hemorrhage, lower incidence of necrotizing enterocolitis and the need for transfusions in preterm infants. The writers held a number of multidisciplinary simulation workshops of vaginal and Caesarean deliveries, with providers starting positive pressure ventilation and ending with CPAP on a preterm manikin. Videos were also reviewed and identified 5 themes of concern: sterility, equipment, mobility, space, and workflow.
AHRQ-funded; HS023506.
Citation: Lapcharoensap W, Cong A, Sherman J .
Safety and ergonomic challenges of ventilating a premature infant during delayed cord clamping.
Children 2019 Apr 13;6(4). doi: 10.3390/children6040059..
Keywords: Adverse Events, Labor and Delivery, Newborns/Infants, Patient Safety
Farra S, Hodgson E, Miller ET
Effects of virtual reality simulation on worker emergency evacuation of neonates.
This study compared differences in learning outcomes among newborn intensive care unit (NICU) workers who underwent emergency evacuation training either with virtual reality simulation (VRS) or web-based clinical updates (CU). The workers were evaluated based on knowledge gained, confidence with evacuation, and performance in a live evacuation exercise. Workers were randomly assigned to VRS or CU. The groups did not statistically differ based on Cognitive Assessment scores or self-evaluations. However, the VRS group performed statistically better than the CU group in the live exercise. This study points to the effectiveness of virtual reality training.
AHRQ-funded; HS023149.
Citation: Farra S, Hodgson E, Miller ET .
Effects of virtual reality simulation on worker emergency evacuation of neonates.
Disaster Med Public Health Prep 2019 Apr;13(2):301-08. doi: 10.1017/dmp.2018.58..
Keywords: Emergency Preparedness, Newborns/Infants, Intensive Care Unit (ICU), Simulation, Training, Education: Continuing Medical Education
Kahwati LC, Sorensen AV, Teixeira-Poit S
AHRQ Author: Mistry KB
Impact of the Agency for Healthcare Research and Quality's Safety Program for Perinatal Care.
The purpose of this study was to describe the Safety Program for Perinatal Care (SPPC) implementation experience and evaluate the short-term impact on labor and delivery (L&D) unit patient safety culture, processes, and adverse events. SPPC implementation by L&D units were supported sing a program toolkit, trainings, and technical assistance. Researchers then evaluated the program using a pre-post, mixed-methods design. Changes in safety and quality were measured using the Modified Adverse Outcome Index (MAOI) and other perinatal care indicators. Findings showed that SPPC had a favorable impact on unit patient safety culture and processes, but mixed short-term impact on maternal and neonatal adverse events.
AHRQ-authored; AHRQ-funded; 2902010000241.
Citation: Kahwati LC, Sorensen AV, Teixeira-Poit S .
Impact of the Agency for Healthcare Research and Quality's Safety Program for Perinatal Care.
Jt Comm J Qual Patient Saf 2019 Apr;45(4):231-40. doi: 10.1016/j.jcjq.2018.11.002..
Keywords: Adverse Events, Communication, Comprehensive Unit-based Safety Program (CUSP), Labor and Delivery, Maternal Care, Newborns/Infants, Outcomes, Patient Safety, Pregnancy, Simulation, Surveys on Patient Safety Culture, Teams, TeamSTEPPS, Training, Women
Khamash DF, Mongodin EF, White JR
The association between the developing nasal microbiota of hospitalized neonates and Staphylococcus aureus colonization.
This research studied the association between hospitalized neonates who develop Staphylococcus aureus infections and nasal microbiota populations that preceded infection. Nares samples were obtained for neonates who were screened weekly for S. aureus. DNA was extracted and DNA of the bacterias were sequenced. It was found that controls and treated cases had a higher abundance of genes that contributed to the synthesis of natural antimicrobial compounds from several commensal bacterial types.
AHRQ-funded; HS022872.
Citation: Khamash DF, Mongodin EF, White JR .
The association between the developing nasal microbiota of hospitalized neonates and Staphylococcus aureus colonization.
Open Forum Infect Dis 2019 Apr;6(4):ofz062. doi: 10.1093/ofid/ofz062..
Keywords: Healthcare-Associated Infections (HAIs), Hospitalization, Hospitals, Infectious Diseases, Newborns/Infants