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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 4 of 4 Research Studies DisplayedLin D, Lapen K, Sherer MV
A systematic review of contouring guidelines in radiation oncology: analysis of frequency, methodology, and delivery of consensus recommendations.
Clinical trials have described variation in radiation therapy plan quality, of which contour delineation is a key component, and linked this to inferior patient outcomes. In response, consensus guidelines have been developed to standardize contour delineation. This investigation assessed trends in contouring guidelines and examined the methodologies used to generate and deliver recommendations. The investigators concluded that this review highlighted an increase in consensus contouring recommendations over time.
AHRQ-funded; HS026881.
Citation: Lin D, Lapen K, Sherer MV .
A systematic review of contouring guidelines in radiation oncology: analysis of frequency, methodology, and delivery of consensus recommendations.
Int J Radiat Oncol Biol Phys 2020 Jul 15;107(4):827-35. doi: 10.1016/j.ijrobp.2020.04.011..
Keywords: Guidelines, Evidence-Based Practice, Research Methodologies
Krist AH, Barry MJ, Wolff TA
AHRQ Author: Wolff TA, Fan TM
Evolution of the U.S. Preventive Services Task Force's methods.
In this commentary on an article appearing in the same issue, the authors stated that the methods used by the USPSTF deliberately set a high bar for making evidence-based recommendations. They indicated that consumers of preventive service guidelines need to know concretely what is known and unknown and further need confidence that what is being recommended is not influenced by economic or political pressures or by professional opinion with a limited evidence basis.
AHRQ-authored.
Citation: Krist AH, Barry MJ, Wolff TA .
Evolution of the U.S. Preventive Services Task Force's methods.
Am J Prev Med 2020 Mar;58(3):332-35. doi: 10.1016/j.amepre.2019.11.003..
Keywords: U.S. Preventive Services Task Force (USPSTF), Guidelines, Evidence-Based Practice, Prevention, Research Methodologies
Camp KM, Parisi MA, Acosta PB
AHRQ Author: Chang CS
Phenylketonuria Scientific Review Conference: state of the science and future research needs.
An NIH State-of-the-Science Conference was convened in 2012 to address new findings, particularly the use of the medication sapropterin to treat some individuals with phenylketonuria (PKU), and to develop a research agenda. An AHRQ Evidence-based Practice Center conducted a systematic review of adjuvant treatments for PKU and presented its conclusions at the conference. New drugs that are safe, efficacious, and impact a larger proportion of individuals with PKU are needed. The identification of a research agenda has facilitated the development of clinical practice guidelines by professional organizations and serves as a model for other inborn errors of metabolism.
AHRQ-authored.
Citation: Camp KM, Parisi MA, Acosta PB .
Phenylketonuria Scientific Review Conference: state of the science and future research needs.
Mol Genet Metab 2014 Jun;112(2):87-122. doi: 10.1016/j.ymgme.2014.02.013.
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Keywords: Comparative Effectiveness, Evidence-Based Practice, Guidelines, Medication, Research Methodologies
Lawrence WF
AHRQ Author: Lawrence WF
Comparative effectiveness research in practice and policy for radiation oncology.
In radiation oncology, the line between comparative effectiveness research (CER) and traditional research may be blurred, but an increased emphasis on CER can help to bridge the research enterprise and clinical practice, helping to inform decision making at the patient, clinician, and policy levels.
AHRQ-authored.
Citation: Lawrence WF .
Comparative effectiveness research in practice and policy for radiation oncology.
Semin Radiat Oncol 2014 Jan;24(1):54-60. doi: 10.1016/j.semradonc.2013.09.001.
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Keywords: Comparative Effectiveness, Evidence-Based Practice, Guidelines, Policy, Research Methodologies