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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 5 of 5 Research Studies DisplayedGliklich RE, Leavy MB, Cosgrove L
AHRQ Author: Berliner E
Harmonized outcome measures for use in depression patient registries and clinical practice.
This project’s goal was to develop a minimum set of standardized outcome measures relevant to both patients and clinicians that can be collected in depression registries and clinical practice. A multi-stakeholder panel categorized the 27 identified measures using AHRQ's supported Outcome Measures Framework. The panel then identified 10 broadly relevant measures and harmonized definitions for these measures. These harmonized measures represent a minimum set of outcomes that are relevant to clinicians and patients and appropriate for use in depression research and clinical practice.
AHRQ-authored; AHRQ-funded; 290201400004C.
Citation: Gliklich RE, Leavy MB, Cosgrove L .
Harmonized outcome measures for use in depression patient registries and clinical practice.
Ann Intern Med 2020 Jun 16;172(12):803-09. doi: 10.7326/m19-3818..
Keywords: Registries, Depression, Behavioral Health, Outcomes, Patient-Centered Outcomes Research
Coley RY, Boggs JM, Beck A
Defining success in measurement-based care for depression: a comparison of common metrics.
This study compared response and remission measures with effect size and severity-adjusted effect size (SAES) measures and examined the relationship between baseline symptom severity and treatment success for depression. Electronic records from two large integrated health systems were used to identify new psychotherapy episodes. Findings showed that response was preferable for comparing treatment outcomes, as it did not favor more or less baseline symptom severity, indicated clinically meaningful improvement, and was transparent and easy to calculate.
AHRQ-funded; HS026369.
Citation: Coley RY, Boggs JM, Beck A .
Defining success in measurement-based care for depression: a comparison of common metrics.
Psychiatr Serv 2020 Apr;71(4):312-18. doi: 10.1176/appi.ps.201900295..
Keywords: Depression, Behavioral Health, Patient-Centered Outcomes Research, Outcomes, Quality of Care, Quality Measures
Yaramala SR, McElroy SL, Geske J
The impact of binge eating behavior on lithium- and quetiapine-associated changes in body weight, body mass index, and waist circumference during 6 months of treatment: Findings from the bipolar CHOICE study.
Lithium and quetiapine can cause weight gain, but their comparative longer term anthropometric effects are unknown, as are the potential moderating effects of baseline binge-eating (BE) behavior. In this research, the investigators assessed 6 month changes in body weight, body mass index (BMI) and waist circumference in 482 adults with DSM-IV bipolar disorders who participated in a comparative effectiveness study of lithium and quetiapine with evidence-based adjunctive treatment (Bipolar CHOICE).
AHRQ-funded; HS019371.
Citation: Yaramala SR, McElroy SL, Geske J .
The impact of binge eating behavior on lithium- and quetiapine-associated changes in body weight, body mass index, and waist circumference during 6 months of treatment: Findings from the bipolar CHOICE study.
months of treatment: Findings from the bipolar CHOICE study.
J Affect Disord 2020 Apr 1;266:772-81. doi: 10.1016/j.jad.2018.09.025.
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J Affect Disord 2020 Apr 1;266:772-81. doi: 10.1016/j.jad.2018.09.025.
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Keywords: Behavioral Health, Medication, Obesity, Comparative Effectiveness, Patient-Centered Outcomes Research, Evidence-Based Practice, Outcomes
Crits-Christoph P, Gallop R, Gaines A
Instrumental variable analyses for causal inference: application to multilevel analyses of the alliance-outcome relation.
In this paper, researchers introduced readers to instrumental variable analyses for causal inferences, using as an example a test of the hypothesis that the quality of the therapeutic alliance has a causal role in relation to the outcome of psychotherapy. They reported that their results supported their hypothesis that, at least at the therapist level, the alliance plays a causal role in producing better outcomes. They recommended that instrumental variable analyses be used as a tool to supplement standard analyses.
AHRQ-funded; HS022124; HS018440.
Citation: Crits-Christoph P, Gallop R, Gaines A .
Instrumental variable analyses for causal inference: application to multilevel analyses of the alliance-outcome relation.
Psychother Res 2020 Jan;30(1):53-67. doi: 10.1080/10503307.2018.1544724..
Keywords: Depression, Behavioral Health, Outcomes, Patient-Centered Outcomes Research, Comparative Effectiveness
Mooney TK, Gibbons MB, Gallop R
Psychotherapy credibility ratings: patient predictors of credibility and the relation of credibility to therapy outcome.
The researchers examined the relation between credibility ratings for adult psychotherapies and various patient factors as well as the relation between credibility ratings and subsequent symptom change. Their findings indicate that patient beliefs after a brief exposure to treatment may influence symptom improvement. Age and education may influence the patient’s beliefs about the credibility of a treatment.
AHRQ-funded; HS022124.
Citation: Mooney TK, Gibbons MB, Gallop R .
Psychotherapy credibility ratings: patient predictors of credibility and the relation of credibility to therapy outcome.
Psychother Res 2014;24(5):565-77. doi: 10.1080/10503307.2013.847988..
Keywords: Anxiety, Depression, Behavioral Health, Outcomes, Patient-Centered Outcomes Research