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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 25 of 253 Research Studies DisplayedRodriguez DV, Lawrence K, Luu S
Development of a computer-aided text message platform for user engagement with a digital diabetes prevention program: a case study.
Investigators partnered with a Digital Diabetes Prevention Programs (dDPP) vendor to develop a personalized automatic message system (PAMS) to promote user engagement to the dDPP platform by sending messages on behalf of the user’s primary care provider. In this article, they discussed the design and development of their system, including key requirements and features, the technical architecture and build, and preliminary user testing.
AHRQ-funded; HS026120.
Citation: Rodriguez DV, Lawrence K, Luu S .
Development of a computer-aided text message platform for user engagement with a digital diabetes prevention program: a case study.
J Am Med Inform Assoc 2021 Dec 28;29(1):155-62. doi: 10.1093/jamia/ocab206..
Keywords: Telehealth, Health Information Technology (HIT), Diabetes, Prevention
James TG, Sullivan MK, Butler JD
Promoting health equity for deaf patients through the electronic health record.
This perspective article outlines barriers to health equity research serving deaf and hard-of-hearing (DHH) American Sign Language users due to systems developed by large-scale informatics networks and to institutional policies on self-serve cohort discovery tools. The authors list potential ways to help adequate capture of language status of DHH American Sign Language users in order to promote health equity for this population.
AHRQ-funded; HS027537.
Citation: James TG, Sullivan MK, Butler JD .
Promoting health equity for deaf patients through the electronic health record.
J Am Med Inform Assoc 2021 Dec 28;29(1):213-16. doi: 10.1093/jamia/ocab239..
Keywords: Electronic Health Records (EHRs), Health Information Technology (HIT), Disabilities
Li LX, Szymczak JE, Keller SC
Antibiotic stewardship in direct-to-consumer telemedicine: translating interventions into the virtual realm.
This article discusses using the core elements for outpatient antibiotic stewardship as a framework for direct-to-consumer (DTC) telemedicine. There is limited scholarship regarding adapting and implementing antibiotic stewardship principles in this setting. The authors discussed utilizing the core elements for outpatient antibiotic stewardship as a framework for efforts moving forward.
AHRQ-funded; HS027819.
Citation: Li LX, Szymczak JE, Keller SC .
Antibiotic stewardship in direct-to-consumer telemedicine: translating interventions into the virtual realm.
J Antimicrob Chemother 2021 Dec 24;77(1):13-15. doi: 10.1093/jac/dkab371..
Keywords: Antibiotics, Antimicrobial Stewardship, Medication, Telehealth, Health Information Technology (HIT)
Kilgallon JL, Gannon M, Burns Z
Multicomponent intervention to improve blood pressure management in chronic kidney disease: a protocol for a pragmatic clinical trial.
This study’s objective is to develop an intervention for the primary care management of uncontrolled hypertension (HTN) in chronic kidney disease (CKD) utilizing user-centered design principles and behavioral economic principles, test the effectiveness of that intervention, and collect implementation data that will facilitate the application of the intervention in other practice settings. One hundred and eighty-four eligible clinical physicians from 15 practices of The Brigham and Women's Practice -Based Research Network are enrolled in the study. The researchers will use the Reach Effectiveness Adoption Implementation Maintenance framework to assess the intervention’s effectiveness in impacting a change in mean systolic blood pressure between baseline and 6 months.
AHRQ-funded; 233201500020I; HS026506; HS028127.
Citation: Kilgallon JL, Gannon M, Burns Z .
Multicomponent intervention to improve blood pressure management in chronic kidney disease: a protocol for a pragmatic clinical trial.
BMJ Open 2021 Dec 22;11(12):e054065. doi: 10.1136/bmjopen-2021-054065..
Keywords: Blood Pressure, Kidney Disease and Health, Chronic Conditions, Clinical Decision Support (CDS), Health Information Technology (HIT)
Peipert JD, Lad T, Khosla PG
A low literacy, multimedia health information technology intervention to enhance patient-centered cancer care in safety net settings increased cancer knowledge in a randomized controlled trial.
In this study, the investigators tested whether a low-literacy-friendly, multimedia information and assessment system used in daily clinical practice enhanced patient-centered care and improved patient outcomes. This was a prospective, parallel-group, randomized controlled trial with 2 arms, CancerHelp-Talking Touchscreen (CancerHelp-TT) versus control, among adults with Stage I-III breast or colorectal cancer receiving chemotherapy and/or radiation therapy in safety net settings.
AHRQ-funded; HS017300.
Citation: Peipert JD, Lad T, Khosla PG .
A low literacy, multimedia health information technology intervention to enhance patient-centered cancer care in safety net settings increased cancer knowledge in a randomized controlled trial.
Cancer Control 2021 Jan-Dec;28:10732748211036783. doi: 10.1177/10732748211036783..
Keywords: Health Literacy, Patient-Centered Healthcare, Cancer, Education: Patient and Caregiver, Health Information Technology (HIT)
Fong A, Behzad S, Pruitt Z
A machine learning approach to reclassifying miscellaneous patient safety event reports.
This research paper describes an effort to develop a machine learning natural language processing model to reclassify medical adverse events that were classified as “miscellaneous” as opposed to a specific event-type category. The authors integrated the model into a clinical workflow dashboard, evaluated user feedback, and compared differences in user thresholds for model performance to reclassify those reports.
AHRQ-funded; HS026481.
Citation: Fong A, Behzad S, Pruitt Z .
A machine learning approach to reclassifying miscellaneous patient safety event reports.
J Patient Saf 2021 Dec 1;17(8):e829-e33. doi: 10.1097/pts.0000000000000731..
Keywords: Patient Safety, Health Information Technology (HIT), Medical Errors
Kalwani NM, Wang KM, Johnson AN
Application of the quadruple aim to evaluate the operational impact of a telemedicine program.
This study compared the operational impact of a telemedicine program called CardioClick at a preventive cardiology clinic compared to traditional clinic visits. The authors examined data for 134 patients enrolled in CardioClick with 181 video follow-up visits and 276 patients enrolled in the clinic’s traditional program with 694 in-person follow-up visits. The Quadruple Aim was used to evaluate CardioClick. Both cohorts were similar in characteristics in terms of age, gender balance, and baseline clinical characteristics. Video follow-up visits were shorter in time for clinicians (median 22 vs 30 minutes) than in-person visits and total clinic time (median 22 vs 68 minutes). Video visits were more likely to end on time than in-person visits as well. Physicians more often completed video visit documentation on the day of the visit.
AHRQ-funded; HS026128.
Citation: Kalwani NM, Wang KM, Johnson AN .
Application of the quadruple aim to evaluate the operational impact of a telemedicine program.
Healthc 2021 Dec;9(4):100593. doi: 10.1016/j.hjdsi.2021.100593..
Keywords: Telehealth, Health Information Technology (HIT), Cardiovascular Conditions, COVID-19
Greenberg JK, Ahluwalia R, Hill M
Development and external validation of the KIIDS-TBI tool for managing children with mild traumatic brain injury and intracranial injuries.
This study's objectives were to develop a new risk model with improved sensitivity compared to the CHIIDA model for the post-neuroimaging management of children with mild traumatic brain injuries (mTBI) and intracranial injuries and further to validate externally the new model and CHIIDA model in a multicenter data set. Findings showed that the KIIDS-TBI model had high sensitivity and moderate specificity for risk stratifying children with mTBI and intracranial injuries. The researchers concluded that the use of their clinical decision support tool may help improve the safe, resource-efficient management of this important patient population.
AHRQ-funded; HS027075.
Citation: Greenberg JK, Ahluwalia R, Hill M .
Development and external validation of the KIIDS-TBI tool for managing children with mild traumatic brain injury and intracranial injuries.
Acad Emerg Med 2021 Dec;28(12):1409-20. doi: 10.1111/acem.14333..
Keywords: Children/Adolescents, Brain Injury, Clinical Decision Support (CDS), Decision Making, Health Information Technology (HIT)
Pruitt ZM, Howe JL, Hettinger AZ
Emergency physician perceptions of electronic health record usability and safety.
Investigators sought to identify emergency physicians' perceived electronic health record (EHR) usability and safety strengths and shortcomings across major EHR vendor products. They found that the 3 most commonly discussed usability topics were Workflow Support (shortcoming), Visual Display (strength), and Data Entry. Fourteen cross-hospital/cross-vendor themes, 6 vendor-specific themes, and 4 hospital-specific themes emerged as well.
AHRQ-funded; HS025136.
Citation: Pruitt ZM, Howe JL, Hettinger AZ .
Emergency physician perceptions of electronic health record usability and safety.
J Patient Saf 2021 Dec 1;17(8):e983-e87. doi: 10.1097/pts.0000000000000849..
Keywords: Emergency Department, Electronic Health Records (EHRs), Health Information Technology (HIT), Patient Safety
McAlearney AS, Sieck CJ, Gregory ME
Examining patients' capacity to use patient portals: insights for telehealth.
The objective of this study was to examine factors related to patients' capacity to use a patient portal and test the impact of these factors on patients' portal use. Using data from a large-scale randomized controlled trial of patient portal use, over one thousand hospitalized patients responded to survey items that were then mapped onto the 4 dimensions of the Engagement Capacity Framework. Findings showed that patients with fewer resources, fewer capabilities, lower willingness, and lower overall capacity to use patient portals used the portal less; in contrast, those with lower perceived self-efficacy used the portal more. These differences in patients' capacity to use patient portals provide an initial understanding of factors that may influence the use of telehealth and offer important guidance in efforts to support patients' telehealth use.
AHRQ-funded; HS024379; HS024091; HS024349.
Citation: McAlearney AS, Sieck CJ, Gregory ME .
Examining patients' capacity to use patient portals: insights for telehealth.
Med Care 2021 Dec;59(12):1067-74. doi: 10.1097/mlr.0000000000001639..
Keywords: Telehealth, Health Information Technology (HIT), Patient and Family Engagement
Abraham J, Meng A, Holzer KJ
Exploring patient perspectives on telemedicine monitoring within the operating room.
The authors sought to identify participant-rated items contributing to patient attitudes, beliefs, and level of comfort with electronic OR (eOR) monitoring and to highlight barriers and facilitators to eOR use. They found that participants expressed significant support for intraoperative telemedicine use and greater comfort with local telemedicine systems instead of long-distance telemedicine systems. They further found that reservations centered on organizational policies, procedures, environment, culture; people; workflow and communication; and hardware and software.
Citation: Abraham J, Meng A, Holzer KJ .
Exploring patient perspectives on telemedicine monitoring within the operating room.
Int J Med Inform 2021 Dec;156:104595. doi: 10.1016/j.ijmedinf.2021.104595..
Keywords: Telehealth, Health Information Technology (HIT), Surgery, Patient Experience
Iqbal AR, Parau CA, Kazi S
Identifying electronic medication administration record (eMAR) usability issues from patient safety event reports.
This study investigated the contribution of usability challenges associated with the electronic medication administration record (eMAR) to medication errors using patient safety event reports (PSEs). The authors analyzed free-text descriptions of 849 medication-related PSEs selected from 2.3 million reports. Specific health IT components, usability challenge categories, and nuanced usability themes that contributed to each PSE were identified by coders. Usability challenges included workflow support, alerting, and display/visual clutter.
AHRQ-funded; HS025136.
Citation: Iqbal AR, Parau CA, Kazi S .
Identifying electronic medication administration record (eMAR) usability issues from patient safety event reports.
Jt Comm J Qual Patient Saf 2021 Dec;47(12):793-801. doi: 10.1016/j.jcjq.2021.09.004..
Keywords: Electronic Prescribing (E-Prescribing), Health Information Technology (HIT), Medication, Medical Errors, Patient Safety
Adams KT, Pruitt Z, Kazi S
Identifying health information technology usability issues contributing to medication errors across medication process stages.
Researchers sought to identify the types of medication errors associated with health IT use, whether they reached the patient, where in the medication process those errors occurred, and the specific usability issues contributing to those errors. They found that health IT usability issues were a prevalent contributing factor to medication errors, many of which reach the patient. They recommended that data entry, workflow support, and alerting be prioritized during usability and safety optimization efforts.
AHRQ-funded; HS025136.
Citation: Adams KT, Pruitt Z, Kazi S .
Identifying health information technology usability issues contributing to medication errors across medication process stages.
J Patient Saf 2021 Dec 1;17(8):e988-e94. doi: 10.1097/pts.0000000000000868..
Keywords: Medication, Health Information Technology (HIT), Medical Errors, Adverse Drug Events (ADE), Adverse Events, Patient Safety
Coley RY, Boggs JM, Beck A
Predicting outcomes of psychotherapy for depression with electronic health record data.
This study evaluated models for predicting outcomes of psychotherapy for depression in a clinical practice setting. Findings showed that prediction models did not accurately predict depression treatment outcomes despite using rich electronic health record data and advanced analytic techniques. Recommendations included caution when considering prediction models for psychiatric outcomes using baseline intake information and transparent research to evaluate performance of any model intended for clinical use.
AHRQ-funded; HS026369.
Citation: Coley RY, Boggs JM, Beck A .
Predicting outcomes of psychotherapy for depression with electronic health record data.
J Affect Disord Rep 2021 Dec;6:100198. doi: 10.1016/j.jadr.2021.100198..
Keywords: Depression, Behavioral Health, Electronic Health Records (EHRs), Health Information Technology (HIT), Patient-Centered Outcomes Research, Outcomes
Hayden EM, Davis C, Clark S
Telehealth in emergency medicine: a consensus conference to map the intersection of telehealth and emergency medicine.
Through the 2020 Society for Academic Emergency Medicine's annual consensus conference, experts in emergency medicine (EM) and telehealth created a research agenda to explore how EM should intersect with telehealth. The multiyear process resulted in consensus with a final set of 24 important research questions. The primary finding from the process was the breadth of gaps in the evidence for telehealth in EM and telehealth in general. The consensus process identified priority research questions for the use of and evaluation of telehealth in EM to fill the current knowledge gaps.
AHRQ-funded; HS027528.
Citation: Hayden EM, Davis C, Clark S .
Telehealth in emergency medicine: a consensus conference to map the intersection of telehealth and emergency medicine.
Acad Emerg Med 2021 Dec;28(12):1452-74. doi: 10.1111/acem.14330..
Keywords: Telehealth, Health Information Technology (HIT), Emergency Department, COVID-19
Schirle L, Jeffery A, Yaqoob A
Two data-driven approaches to identifying the spectrum of problematic opioid use: a pilot study within a chronic pain cohort.
Although electronic health records (EHR) have significant potential for the study of opioid use disorders (OUD), detecting OUD in clinical data is challenging. Models using EHR data to predict OUD often rely on case/control classifications focused on extreme opioid use. IN this study, the investigators discussed two data-driven approaches to identifying the spectrum of problematic opioid use. The investigators concluded that risk scores comprising comorbidities and text offer differing but synergistic insights into characterizing problematic opioid use.
AHRQ-funded; HS026395.
Citation: Schirle L, Jeffery A, Yaqoob A .
Two data-driven approaches to identifying the spectrum of problematic opioid use: a pilot study within a chronic pain cohort.
Int J Med Inform 2021 Dec;156:104621. doi: 10.1016/j.ijmedinf.2021.104621..
Keywords: Opioids, Pain, Chronic Conditions, Medication, Health Information Technology (HIT)
Abraham CM, Zheng K, Norful AA
Use of multifunctional electronic health records and burnout among primary care nurse practitioners.
This study investigated whether there is an association with the use of multifunctional electronic health records (EHRs) with nurse practitioner (NP) burnout in primary care practices. The study used cross-sectional survey data secondary analysis collected from NPs in Pennsylvania and New Jersey. The NPs completed surveys measuring burnout, use of multifunctional EHRs, demographics, and characteristics of their practice. Of 396 NPs included, 25.3% reported burnout, but the use of multifunctional EHRs did not increase primary care NP burnout.
AHRQ-funded; HS027290.
Citation: Abraham CM, Zheng K, Norful AA .
Use of multifunctional electronic health records and burnout among primary care nurse practitioners.
J Am Assoc Nurse Pract 2021 Dec;33(12):1182-89. doi: 10.1097/jxx.0000000000000533..
Keywords: Electronic Health Records (EHRs), Health Information Technology (HIT), Burnout, Provider: Nurse, Primary Care
Wang M, Pantell MS, Gottlieb LM
Documentation and review of social determinants of health data in the EHR: measures and associated insights.
Electronic Health Records (EHRs) increasingly include designated fields to capture social determinants of health (SDOH). The investigators developed measures to characterize their use, and use of other SDOH data types, to optimize SDOH data integration. The investigators concluded for their institution, measures revealed substantial variation across data types, suggesting the need to engage in efforts such as EHR-user education and targeted workflow integration. They also concluded that measures revealed opportunities to optimize SDOH data documentation and review.
AHRQ-funded; HS026383.
Citation: Wang M, Pantell MS, Gottlieb LM .
Documentation and review of social determinants of health data in the EHR: measures and associated insights.
J Am Med Inform Assoc 2021 Nov 25;28(12):2608-16. doi: 10.1093/jamia/ocab194..
Keywords: Social Determinants of Health, Electronic Health Records (EHRs), Health Information Technology (HIT)
Lafferty M, Harrod M, Krein S
It's like sending a message in a bottle: a qualitative study of the consequences of one-way communication technologies in hospitals.
Researchers examined how physicians and nurses use available communication technologies and identify the implications for communication and patient care based on the theory of workarounds. They found that one-way communication technologies created an environment where workarounds could flourish. By placing results within the context of the theory of workarounds, they extended what is known about why and how workarounds develop, and they offered strategies to minimize workarounds' adverse effects. They concluded that two-way communication technologies could minimize workarounds and gaps in information exchange and could reduce unnecessary interruptions and the potential for adverse events.
J Am Med Inform Assoc 2021 Nov 25;28(12):2601-07. doi: 10.1093/jamia/ocab191.
Citation: Lafferty M, Harrod M, Krein S .
It's like sending a message in a bottle: a qualitative study of the consequences of one-way communication technologies in hospitals.
AHRQ-funded; HS022305..
Keywords: Hospitals, Communication, Health Information Technology (HIT), Provider: Physician
Rogers H, Madathil KC, Joseph A
An exploratory study investigating the barriers, facilitators, and demands affecting caregivers in a telemedicine integrated ambulance-based setting for stroke care.
This study investigates the impact of telemedicine on workload, teamwork, workflow, and communication of geographically distributed caregivers delivering stroke care in ambulance-based telemedicine. Simulated stroke sessions were conducted with selected caregivers, then followed with a survey and interviews. Findings showed that barriers included frustration with equipment, the loss of personal connection of the neurologists with the patients, and physical constraints in the ambulance. Facilitators included live visual communication increasing teamwork and efficiency, the ease of access to neurologist, increased flexibility, and high overall satisfaction and usability.
AHRQ-funded; HS026809.
Citation: Rogers H, Madathil KC, Joseph A .
An exploratory study investigating the barriers, facilitators, and demands affecting caregivers in a telemedicine integrated ambulance-based setting for stroke care.
Appl Ergon 2021 Nov;97:103537. doi: 10.1016/j.apergo.2021.103537..
Keywords: Telehealth, Health Information Technology (HIT), Caregiving, Stroke, Cardiovascular Conditions, Emergency Medical Services (EMS)
Hsueh L, Huang J, Millman AK
Disparities in use of video telemedicine among patients with limited English proficiency during the COVID-19 pandemic.
The authors hypothesized that limited English proficiency (LEP) would be associated with lower video use compared with telephone, especially among patients without prior video visit experience. They found that one-third of patients with LEP scheduled a visit by video instead of telephone. Patients with LEP chose video less often than patients without LEP, even after adjusting for technology factors. However, among patients with prior video visit experience, no significant difference in video visit use by LEP was found.
AHRQ-funded; HS025189.
Citation: Hsueh L, Huang J, Millman AK .
Disparities in use of video telemedicine among patients with limited English proficiency during the COVID-19 pandemic.
JAMA Netw Open 2021 Nov;4(11):e2133129. doi: 10.1001/jamanetworkopen.2021.33129..
Keywords: COVID-19, Telehealth, Health Information Technology (HIT), Disparities, Communication
Chartash D, Sharifi M, Emerson B
Documentation of shared decisionmaking in the emergency department.
Patient-centered communication and shared decision making is a vital element of clinical practice, but little is known about its impact or value in the emergency department (ED) setting. The researchers of this study developed a natural language processing tool using regular expressions to identify shared decision making, patient-centered communications, and to describe visit-, site-, and temporal-level patterns within a large health system. The study took place in two parts: part 1 was the development and validation of the natural language processing tool, and part 2 was a retrospective analysis of shared decision making and patient discussion using the processing tool to assess ED physician and advanced practitioner documentation from 2013 to 2020. Compared to chart review of 600 ED notes, the accuracy rates of the natural language processing tool were 96.7% and 88.9% respectively. Between 2013 to 2020 the researchers observed greater likelihood of shared decision-making documentation among physicians vs advanced practice providers, higher likelihood among female vs male patients, and lower likelihood of shared decision-making in Black patients compared with White patients. The researchers also found that patient discussion and shared decision-making were associated with higher levels of commercial insurance status and level of triage. The study concluded that a natural language processing tool was developed, validated, and utilized to identify incidences of shared decision making from ED documentation, with the researchers finding multiple possible factors which contribute to variation in shared decision making.
AHRQ-funded; HS025701.
Citation: Chartash D, Sharifi M, Emerson B .
Documentation of shared decisionmaking in the emergency department.
Ann Emerg Med 2021 Nov;78(5):637-49. doi: 10.1016/j.annemergmed.2021.04.038..
Keywords: Decision Making, Emergency Department, Patient-Centered Healthcare, Electronic Health Records (EHRs), Health Information Technology (HIT)
Bowles EJA, O'Neill SC, Li T
Effect of a randomized trial of a web-based intervention on patient-provider communication about breast density.
This study evaluated a personalized web-based intervention between women and their providers designed to improve breast cancer risk communication. This randomized trial included women aged 40-69 years with 504 women in the control group and 492 women who used the intervention website. The website included information about breast density, personalized breast cancer risk, chemoprevention, and magnetic resonance imaging. Participants self-reported their communication about density with providers at 6 weeks and 12 months. Women in the intervention arm were 2.39 times more likely to report density communication at 6 weeks than the control arm. This effect persisted at 12 months. At 6 weeks the effect was only significant among women who reported versus those who did not report any previous density discussions. A quarter of women in each arm did not have a density conversation at any point during the study.
AHRQ-funded; HS022982.
Citation: Bowles EJA, O'Neill SC, Li T .
Effect of a randomized trial of a web-based intervention on patient-provider communication about breast density.
J Womens Health 2021 Nov;30(11):1529-37. doi: 10.1089/jwh.2021.0053.
AHRQ-funded; HS022982..
AHRQ-funded; HS022982..
Keywords: Communication, Women, Cancer: Breast Cancer, Cancer, Health Information Technology (HIT)
Reed M, Huang J, Graetz I
Treatment and follow-up care associated with patient-scheduled primary care telemedicine and in-person visits in a large integrated health system.
Telemedicine visits can offer patients convenient access to a clinician, but it is unclear whether treatment differs from that with in-person visits or how often patients require in-person follow-up. The objectives of this study was to examine whether physician prescribing and orders differed between telemedicine and office visits, whether physicians conducting telemedicine visits were more likely to require in-person follow-up, and whether telemedicine visits were associated with more health events.
AHRQ-funded; HS25189.
Citation: Reed M, Huang J, Graetz I .
Treatment and follow-up care associated with patient-scheduled primary care telemedicine and in-person visits in a large integrated health system.
JAMA Netw Open 2021 Nov;4(11):e2132793. doi: 10.1001/jamanetworkopen.2021.32793..
Keywords: Telehealth, Health Information Technology (HIT), Primary Care
Salwei ME, Carayon P, Hoonakker PLT
Workflow integration analysis of a human factors-based clinical decision support in the emergency department.
Numerous challenges with the implementation, acceptance, and use of health IT are related to poor usability and a lack of integration of the technologies into clinical workflow, and have, therefore, limited the potential of these technologies to improve patient safety. In this paper, the investigators propose a definition and conceptual model of health IT workflow integration. Using interviews of 12 emergency department (ED) physicians, they identified 134 excerpts of barriers and facilitators to workflow integration of a human factors (HF)-based clinical decision support (CDS) implemented in the ED.
AHRQ-funded; HS022086.
Citation: Salwei ME, Carayon P, Hoonakker PLT .
Workflow integration analysis of a human factors-based clinical decision support in the emergency department.
Appl Ergon 2021 Nov;97:103498. doi: 10.1016/j.apergo.2021.103498..
Keywords: Emergency Department, Workflow, Clinical Decision Support (CDS), Health Information Technology (HIT), Implementation