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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 3 of 3 Research Studies DisplayedWhooten R, Kerem L, Stanley T
Physical activity in adolescents and children and relationship to metabolic health.
The purpose of this review was to summarize recent developments relating to the role of physical activity in insulin resistance and increased metabolic health in children and adolescents. Recent findings confirm the role of physical activity in decreasing insulin resistance and metabolic syndrome, but the authors note that the current literature is limited by unstandardized research methods and definitions. Future research that addresses these issues in order to offer targeted physical activity interventions is recommended.
AHRQ-funded; HS000063.
Citation: Whooten R, Kerem L, Stanley T .
Physical activity in adolescents and children and relationship to metabolic health.
Curr Opin Endocrinol Diabetes Obes 2019 Feb;26(1):25-31. doi: 10.1097/med.0000000000000455..
Keywords: Children/Adolescents, Diabetes, Lifestyle Changes, Obesity, Obesity: Weight Management
Azar KM, Chung S, Wang EJ
Impact of education on weight in newly diagnosed type 2 diabetes: every little bit helps.
The researchers sought to evaluate the benefit of participation in more limited counseling and/or education among individuals with newly diagnosed type 2 diabetes in more modest real-world clinical settings. The average weight loss of patients who received counseling/education alone during the follow-up period (up to three years post-exposure to participation) was 6.3 lbs., and, if received with medication prescription, 8.1 lbs. The weight loss associated with medication was only 3.5 lbs.
AHRQ-funded; HS019815.
Citation: Azar KM, Chung S, Wang EJ .
Impact of education on weight in newly diagnosed type 2 diabetes: every little bit helps.
PLoS One 2015 Jun 8;10(6):e0129348. doi: 10.1371/journal.pone.0129348..
Keywords: Diabetes, Education: Patient and Caregiver, Lifestyle Changes, Obesity, Obesity: Weight Management
Romanelli RJ, Chung S, Pu J
Comparative effectiveness of early versus delayed metformin in the treatment of type 2 diabetes.
The purpose of this study was to quantify the effectiveness of early versus delayed initiation of metformin monotherapy on glycemic control (measured by change in HbA1c) and weight modification (change in body mass index [BMI]). It found that treatment with metformin earlier in the course of type 2 diabetes is associated with better glycemic control, more pronounced weight reduction, and a lower risk for therapy intensification than delayed treatment.
AHRQ-funded; HS019815.
Citation: Romanelli RJ, Chung S, Pu J .
Comparative effectiveness of early versus delayed metformin in the treatment of type 2 diabetes.
Diabetes Res Clin Pract 2015 Apr;108(1):170-8. doi: 10.1016/j.diabres.2014.12.019..
Keywords: Diabetes, Medication, Comparative Effectiveness, Obesity: Weight Management, Outcomes