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AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 5 of 5 Research Studies DisplayedKo JY, Hirai AH, Owens PL
AHRQ Author: Owens PL
Neonatal abstinence syndrome and maternal opioid-related diagnoses: analysis of ICD-10-CM transition, 2013-2017.
Researchers sought to evaluate whether the transition from ICD-9-CM to ICD-10-CM may have affected surveillance on rates of neonatal abstinence syndrome (NAS), maternal opioid use disorder (OUD), and opioid-related diagnoses. Using HCUP data, they found that the ICD-10-CM transition did not appear to affect NAS. However, coding of maternal OUD alone may not capture the same population across the transition, potentially confounding the interpretation of trend data spanning this time period.
AHRQ-authored.
Citation: Ko JY, Hirai AH, Owens PL .
Neonatal abstinence syndrome and maternal opioid-related diagnoses: analysis of ICD-10-CM transition, 2013-2017.
Hosp Pediatr 2021 Aug;11(8):902-08. doi: 10.1542/hpeds.2021-005845..
Keywords: Healthcare Cost and Utilization Project (HCUP), Newborns/Infants, Opioids, Medication, Pregnancy, Substance Abuse
Hirai AH, Ko JY, Owens PL
AHRQ Author: Owens PL, Stocks C
Neonatal abstinence syndrome and maternal opioid-Related diagnoses in the US, 2010-2017.
This study analyzed trends in neonatal abstinence syndrome (NAS) and maternal opioid-Related diagnosis (MOD) in the United States from 2010 to 2017. A cross-sectional analysis was done of the HCUP National Inpatient Sample and State Inpatient Database from 2010 through 2017. Diagnoses of NAS and MOD were found using the ICD-10, CM codes. Significant increases occurred in rates of NAS, from 4.0 to 7.3 per birth hospitalizations and MOD, from 3.5 to 8.2 per 1000 delivery hospitalizations. A census of 47 state databases in 2017 found a large range of NAS rates – from 1.3 per 1000 birth hospitalizations in Nebraska to 53.5 per 1000 hospitalizations in West Virginia with the same ranges found for MOD rates. In all states except Nebraska and Vermont which only had significant MOD increases, NAS and MOD rates rose significantly from 2010 to 2017.
AHRQ-authored; AHRQ-funded; 290201800001C.
Citation: Hirai AH, Ko JY, Owens PL .
Neonatal abstinence syndrome and maternal opioid-Related diagnoses in the US, 2010-2017.
Neonatal abstinence syndrome and maternal opioid-Related diagnoses in the US, 2010-2017..
Keywords: Healthcare Cost and Utilization Project (HCUP), Newborns/Infants, Opioids, Medication, Substance Abuse, Hospitalization, Pregnancy
Weinberger DM, Warren JL, Steiner CA
AHRQ Author: Steiner CA
Reduced-dose schedule of prophylaxis based on local data provides near-optimal protection against respiratory syncytial virus.
The researchers considered whether a reduced- dose schedule tailored to the local RSV season in the continental United States would provide adequate protection. They found that a 4-dose schedule of prophylactic injections timed with local RSV epidemics could provide protection comparable to 5 doses and could be considered as a way to improve the cost-effectiveness of prophylaxis.
AHRQ-authored.
Citation: Weinberger DM, Warren JL, Steiner CA .
Reduced-dose schedule of prophylaxis based on local data provides near-optimal protection against respiratory syncytial virus.
Clin Infect Dis 2015 Aug 15;61(4):506-14. doi: 10.1093/cid/civ331..
Keywords: Healthcare Cost and Utilization Project (HCUP), Newborns/Infants, Newborns/Infants, Medication
Weinberger DM, Klugman KP, Steiner CA
AHRQ Author: Steiner CA
Association between respiratory syncytial virus activity and pneumococcal disease in infants: a time series analysis of US hospitalization data.
The researchers evaluated whether variations in respiratory syncytial virus (RSV) epidemic timing and magnitude are associated with variations in pneumococcal disease epidemics and whether changes in pneumococcal disease following the introduction of a pneumococcal conjugate vaccine (PCV7) were associated with changes in the rate of RSV hospitalizations. Their findings indicate that RSV is associated with increases in the incidence of pneumococcal pneumonia.
AHRQ-authored.
Citation: Weinberger DM, Klugman KP, Steiner CA .
Association between respiratory syncytial virus activity and pneumococcal disease in infants: a time series analysis of US hospitalization data.
PLoS Med 2015 Jan 6;12(1):e1001776. doi: 10.1371/journal.pmed.1001776..
Keywords: Healthcare Cost and Utilization Project (HCUP), Newborns/Infants, Respiratory Conditions, Hospitalization
Pitzer VE, Viboud C, Alonso WJ
AHRQ Author: Steiner CA
Environmental drivers of the spatiotemporal dynamics of respiratory syncytial virus in the United States.
The authors examined the association between environmental variables and state-specific measures of respiratory syncytial virus (RSV) seasonality. They found that states with low mean vapor pressure and the largest seasonal variation in potential evapotranspiration tended to experience biennial patterns of RSV activity, with alternating years of "early-big" and "late-small" epidemics. Their results successfully connected environmental drivers to the epidemic dynamics of RSV; however, the results do not fully explain why RSV activity begins in Florida, one of the warmest states, when RSV is a winter-seasonal pathogen.
AHRQ-authored.
Citation: Pitzer VE, Viboud C, Alonso WJ .
Environmental drivers of the spatiotemporal dynamics of respiratory syncytial virus in the United States.
PLoS Pathog 2015 Jan;11(1):e1004591. doi: 10.1371/journal.ppat.1004591.
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Keywords: Children/Adolescents, Healthcare Cost and Utilization Project (HCUP), Newborns/Infants, Infectious Diseases, Respiratory Conditions