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Search All Research Studies
AHRQ Research Studies Date
Topics
- Adverse Drug Events (ADE) (1)
- Adverse Events (1)
- Arthritis (1)
- Blood Thinners (1)
- Cardiovascular Conditions (5)
- Chronic Conditions (1)
- Data (1)
- Depression (1)
- Elderly (1)
- Electronic Health Records (EHRs) (1)
- Evidence-Based Practice (1)
- (-) Heart Disease and Health (10)
- Medication (1)
- Mortality (3)
- Patient-Centered Outcomes Research (1)
- Patient Safety (2)
- Racial and Ethnic Minorities (1)
- Registries (2)
- Respiratory Conditions (1)
- (-) Risk (10)
- Sleep Problems (1)
- Social Determinants of Health (1)
- Stress (1)
- Stroke (2)
- Surgery (1)
AHRQ Research Studies
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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 10 of 10 Research Studies DisplayedO'Brien EC, Simon DN, Thomas LE
The ORBIT bleeding score: a simple bedside score to assess bleeding risk in atrial fibrillation.
The researchers sought to develop and validate a novel bleeding risk score using routinely available clinical information to predict major bleeding in a large, community-based in atrial fibrillation (AF) population. They concluded that their five-element ORBIT bleeding risk score had better ability to predict major bleeding in AF patients when compared with HAS-BLED and ATRIA risk scores.
AHRQ-funded; HS021092.
Citation: O'Brien EC, Simon DN, Thomas LE .
The ORBIT bleeding score: a simple bedside score to assess bleeding risk in atrial fibrillation.
Eur Heart J 2015 Dec 7;36(46):3258-64. doi: 10.1093/eurheartj/ehv476.
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Keywords: Blood Thinners, Heart Disease and Health, Cardiovascular Conditions, Adverse Drug Events (ADE), Adverse Events, Risk, Registries, Patient-Centered Outcomes Research, Evidence-Based Practice
Abdelsattar ZM, Hendren S, Wong SL
The impact of untreated obstructive sleep apnea on cardiopulmonary complications in general and vascular surgery: a cohort study.
The purpose of this study was to determine whether preoperatively untreated obstructive sleep apnea (OSA) affects postoperative outcomes. It found that compared with treated OSA, untreated OSA was independently associated with more cardiopulmonary complications (risk-adjusted rates 6.7 percent versus 4.0 percent; particularly unplanned reintubations and myocardial infarction.
AHRQ-funded; HS000053.
Citation: Abdelsattar ZM, Hendren S, Wong SL .
The impact of untreated obstructive sleep apnea on cardiopulmonary complications in general and vascular surgery: a cohort study.
Sleep 2015 Aug;38(8):1205-10. doi: 10.5665/sleep.4892..
Keywords: Sleep Problems, Surgery, Patient Safety, Risk, Heart Disease and Health, Respiratory Conditions, Chronic Conditions
Kabra R, Cram P, Girotra S
Effect of race on outcomes (stroke and death) in patients >65 years with atrial fibrillation.
The researchers sought to determine whether there are any racial differences in the outcomes of death and stroke in patients with newly diagnosed AF in patients >65 years. They found that the risks of death and stroke are higher in blacks and Hispanics compared with whites. The increased risk was eliminated or significantly reduced after adjusting for preexisting co-morbidities.
AHRQ-funded; HS021992.
Citation: Kabra R, Cram P, Girotra S .
Effect of race on outcomes (stroke and death) in patients >65 years with atrial fibrillation.
Am J Cardiol 2015 Jul 15;116(2):230-5. doi: 10.1016/j.amjcard.2015.04.012..
Keywords: Elderly, Heart Disease and Health, Cardiovascular Conditions, Racial and Ethnic Minorities, Stroke, Mortality, Risk
Qian F, Hannan EL, Pine M
Can adding laboratory values improve risk-adjustment mortality models using clinical percutaneous cardiac intervention registry data?
The authors predicted in-hospital/30-day mortality with and without appended laboratory data using New York's percutaneous coronary intervention registry data from 2008-2010. They found that adding laboratory data did not significantly improve the risk-adjustment mortality models' performance and did not dramatically change the quality assessment of hospitals.
AHRQ-funded; HS019965.
Citation: Qian F, Hannan EL, Pine M .
Can adding laboratory values improve risk-adjustment mortality models using clinical percutaneous cardiac intervention registry data?
J Invasive Cardiol 2015 Jul;27(7):E117-24.
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Keywords: Heart Disease and Health, Mortality, Registries, Risk
Solomon DH, Reed GW, Kremer JM
Disease activity in rheumatoid arthritis and the risk of cardiovascular events.
The researchers studied whether time-averaged disease activity in rheumatoid arthritis (RA) correlates with cardiovascular (CV) events. They found that reduced time-averaged disease activity in RA is associated with fewer CV events.
AHRQ-funded; HS018517.
Citation: Solomon DH, Reed GW, Kremer JM .
Disease activity in rheumatoid arthritis and the risk of cardiovascular events.
Arthritis Rheumatol 2015 Jun;67(6):1449-55. doi: 10.1002/art.39098.
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Keywords: Cardiovascular Conditions, Heart Disease and Health, Arthritis, Risk, Stroke
Dupre ME, George LK, Liu G
Association between divorce and risks for acute myocardial infarction.
This study investigated the association between lifetime exposure to divorce and the incidence of acute myocardial infarction (AMI) in US adults. Divorce is a significant risk factor for AMI. It found that the risks associated with multiple divorces are especially high in women and are not reduced with remarriage.
AHRQ-funded; HS021092.
Citation: Dupre ME, George LK, Liu G .
Association between divorce and risks for acute myocardial infarction.
Circ Cardiovasc Qual Outcomes 2015 May;8(3):244-51. doi: 10.1161/circoutcomes.114.001291..
Keywords: Heart Disease and Health, Risk, Social Determinants of Health
Brooks JM, Cook E, Chapman CG
Statin use after acute myocardial infarction by patient complexity: are the rates right?
The researchers assessed the benefits and risks associated with higher rates of statin use after AMI by baseline patient complexity. Their results provide strong evidence that providers were attempting to individualize statin prescribing to patients after AMI. Statin users after AMI were less complex and had higher rates of prior statin use.
AHRQ-funded; HS019574.
Citation: Brooks JM, Cook E, Chapman CG .
Statin use after acute myocardial infarction by patient complexity: are the rates right?
Med Care 2015 Apr;53(4):324-31. doi: 10.1097/mlr.0000000000000322..
Keywords: Patient Safety, Risk, Cardiovascular Conditions, Heart Disease and Health, Medication
Alcantara C, Muntner P, Edmondson D
Perfect storm: concurrent stress and depressive symptoms increase risk of myocardial infarction or death.
A recently offered psychosocial perfect storm conceptual model hypothesizes amplified risk will occur in those with concurrent stress and depressive symptoms. The authors tested this hypothesis in a large sample of US adults with coronary heart disease. They found that those with low stress and high depressive symptoms or high stress and low depressive symptoms were not at increased risk, while participants with concurrent high stress and high depressive symptoms had increased risk for myocardial infarction or death relative to those with low stress and low depressive symptoms. They concluded that their results provide initial support for a psychosocial perfect storm conceptual model.
AHRQ-funded; HS023009.
Citation: Alcantara C, Muntner P, Edmondson D .
Perfect storm: concurrent stress and depressive symptoms increase risk of myocardial infarction or death.
Circ Cardiovasc Qual Outcomes 2015 Mar;8(2):146-54. doi: 10.1161/circoutcomes.114.001180.
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Keywords: Depression, Heart Disease and Health, Mortality, Risk, Stress
Navar-Boggan AM, Peterson ED, D'Agostino RB
Hyperlipidemia in early adulthood increases long-term risk of coronary heart disease.
The researchers evaluated the association between years of exposure to high cholesterol levels in early adulthood and future coronary heart disease (CHD) risk. They found that cumulative exposure to hyperlipidemia in the fourth and fifth decades of life is associated with a substantially increased risk of CHD in a dose-responsive fashion, even among adults otherwise predicted to have low risk of cardiovascular disease.
AHRQ-funded; HS021092
Citation: Navar-Boggan AM, Peterson ED, D'Agostino RB .
Hyperlipidemia in early adulthood increases long-term risk of coronary heart disease.
Circulation. 2015 Feb 3;131(5):451-8. doi: 10.1161/circulationaha.114.012477..
Keywords: Heart Disease and Health, Cardiovascular Conditions, Risk
Panahiazar M, Taslimitehrani V, Pereira N
Using EHRs and machine learning for heart failure survival analysis.
This study assessed the performance of the Seattle Heart Failure Model using EHRs at Mayo Clinic, and sought to develop a risk prediction model using machine learning techniques that applied routine clinical care data. Its results showed the models which were built using EHR data are more accurate (11 percent improvement in AUC) with the convenience of being more readily applicable in routine clinical care.
AHRQ-funded; HS023077.
Citation: Panahiazar M, Taslimitehrani V, Pereira N .
Using EHRs and machine learning for heart failure survival analysis.
Stud Health Technol Inform 2015;216:40-4..
Keywords: Electronic Health Records (EHRs), Heart Disease and Health, Risk, Data