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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 3 of 3 Research Studies DisplayedSlayton RB, Toth D, Lee BY
Vital signs: estimated effects of a coordinated approach for action to reduce antibiotic-resistant infections in health care facilities - United States.
The researchers analyzed data from CDC's National Healthcare Safety Network and Emerging Infections Program to project the number of health care-associated infections (HAIs) from antibiotic-resistant bacteria or C. difficile both with and without a large scale national intervention that would include interrupting transmission and improved antibiotic stewardship. They found that, with effective action now, more than half a million antibiotic-resistant HAIs could be prevented over 5 years and that a coordinated approach to interrupting transmission is more effective than historical independent facility-based efforts.
AHRQ-funded; HS023317.
Citation: Slayton RB, Toth D, Lee BY .
Vital signs: estimated effects of a coordinated approach for action to reduce antibiotic-resistant infections in health care facilities - United States.
MMWR Morb Mortal Wkly Rep 2015 Aug 7;64(30):826-31.
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Keywords: Antibiotics, Clostridium difficile Infections, Healthcare-Associated Infections (HAIs), Patient Safety, Prevention
Pakyz AL, Patterson JA, Motzkus-Feagans C
Performance of the present-on-admission indicator for Clostridium difficile infection.
The researchers compared performance of a hospital- and community-onset Clostridium difficile infection definition using administrative data to a present on- admission indicator with definitions using clinical surveillance. For hospital-onset C. difficile infection, there was moderate sensitivity (68 percent) and high specificity (93 percent); for community-onset, sensitivity and specificity were high (both 85 percent).
AHRQ-funded; HS018578.
Citation: Pakyz AL, Patterson JA, Motzkus-Feagans C .
Performance of the present-on-admission indicator for Clostridium difficile infection.
Infect Control Hosp Epidemiol 2015 Jul;36(7):838-40. doi: 10.1017/ice.2015.63..
Keywords: Clostridium difficile Infections, Patient Safety, Healthcare-Associated Infections (HAIs), Data
Abdelsattar ZM, Krapohl G, Alrahmani L
Postoperative burden of hospital-acquired Clostridium difficile infection.
This study of 35,363 surgical patients found that 0.51 percent developed a clostridium difficile infection (CDI), with the highest rates occurring after lower-extremity amputation, bowel resection or repair, and gastric or esophageal operations. Post-operative CDI was also associated with higher rates of extended length of stay, emergency room presentations, and readmissions.
AHRQ-funded; HS000053
Citation: Abdelsattar ZM, Krapohl G, Alrahmani L .
Postoperative burden of hospital-acquired Clostridium difficile infection.
Infect Control Hosp Epidemiol. 2015 Jan;36(1):40-6. doi: 10.1017/ice.2014.8..
Keywords: Clostridium difficile Infections, Patient Safety, Surgery, Hospitalization