National Healthcare Quality and Disparities Report
Latest available findings on quality of and access to health care
Data
- Data Infographics
- Data Visualizations
- Data Tools
- Data Innovations
- All-Payer Claims Database
- Healthcare Cost and Utilization Project (HCUP)
- Medical Expenditure Panel Survey (MEPS)
- AHRQ Quality Indicator Tools for Data Analytics
- State Snapshots
- United States Health Information Knowledgebase (USHIK)
- Data Sources Available from AHRQ
Search All Research Studies
AHRQ Research Studies Date
Topics
- Adverse Drug Events (ADE) (1)
- Adverse Events (4)
- Ambulatory Care and Surgery (2)
- Arthritis (1)
- Behavioral Health (2)
- Blood Clots (1)
- Blood Pressure (4)
- Blood Thinners (1)
- Cancer (3)
- Cancer: Breast Cancer (1)
- Cancer: Colorectal Cancer (4)
- Cancer: Prostate Cancer (2)
- (-) Cardiovascular Conditions (73)
- Care Management (2)
- Case Study (1)
- Children/Adolescents (4)
- Colonoscopy (1)
- Community-Based Practice (1)
- Comparative Effectiveness (4)
- COVID-19 (1)
- Data (1)
- Depression (4)
- Diabetes (6)
- Diagnostic Safety and Quality (3)
- Dialysis (1)
- Disparities (2)
- Education: Patient and Caregiver (2)
- Elderly (5)
- Electronic Health Records (EHRs) (1)
- Emergency Medical Services (EMS) (1)
- Evidence-Based Practice (6)
- Guidelines (2)
- Healthcare Cost and Utilization Project (HCUP) (2)
- Healthcare Delivery (1)
- Healthcare Utilization (1)
- Health Information Technology (HIT) (2)
- Health Insurance (1)
- Health Literacy (1)
- Heart Disease and Health (23)
- Hospital Discharge (1)
- Hospitalization (2)
- Hospital Readmissions (2)
- Hospitals (4)
- Imaging (4)
- Inpatient Care (2)
- Intensive Care Unit (ICU) (1)
- Kidney Disease and Health (2)
- Medical Devices (1)
- Medicare (2)
- Medication (15)
- Mortality (7)
- Nursing (1)
- Outcomes (10)
- Patient-Centered Healthcare (1)
- Patient-Centered Outcomes Research (12)
- Patient Adherence/Compliance (2)
- Patient and Family Engagement (2)
- Patient Experience (1)
- Patient Safety (5)
- Patient Self-Management (1)
- Pneumonia (1)
- Prevention (6)
- Primary Care (4)
- Provider Performance (1)
- Public Health (1)
- Public Reporting (2)
- Quality Improvement (1)
- Quality Indicators (QIs) (2)
- Quality Measures (2)
- Quality of Care (1)
- Quality of Life (2)
- Racial and Ethnic Minorities (8)
- Registries (3)
- Rehabilitation (1)
- Research Methodologies (2)
- Respiratory Conditions (1)
- Risk (14)
- Sepsis (1)
- Sex Factors (2)
- Shared Decision Making (3)
- Social Determinants of Health (2)
- Stress (2)
- Stroke (4)
- Surgery (9)
- Teams (2)
- Telehealth (2)
- Training (1)
- Transitions of Care (1)
- Treatments (2)
- U.S. Preventive Services Task Force (USPSTF) (4)
- Urban Health (1)
- Vulnerable Populations (1)
- Women (1)
- Young Adults (1)
AHRQ Research Studies
Sign up: AHRQ Research Studies Email updates
Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
51 to 73 of 73 Research Studies DisplayedMcConnell KJ, Lindrooth RC, Wholey DR
Modern management practices and hospital admissions.
The researchers investigated whether the modern management practices and publicly reported performance measures are associated with choice of hospital for patients with acute myocardial infarction (AMI). They found that, overall, a one standard deviation change in management practice scores is associated with an 8% increase in AMI admissions.
AHRQ-funded; HS018466.
Citation: McConnell KJ, Lindrooth RC, Wholey DR .
Modern management practices and hospital admissions.
Health Econ 2016 Apr;25(4):470-85. doi: 10.1002/hec.3171.
.
.
Keywords: Hospitals, Heart Disease and Health, Cardiovascular Conditions, Quality Indicators (QIs), Quality Measures, Quality of Care, Public Reporting, Provider Performance
Redmond N, Booth JN, 3rd, Tanner RM
Prevalence of masked hypertension and its association with subclinical cardiovascular disease in African Americans: results from the Jackson Heart Study.
Using data from the Jackson Heart Study, an exclusively African American population-based cohort, the researchers evaluated the association of masked hypertension and prehypertension with left ventricular mass index and common carotid intima media thickness. Masked hypertension was common among African Americans with prehypertension and also normal clinic blood pressure, and was associated with subclinical cardiovascular disease.
AHRQ-funded; HS023009.
Citation: Redmond N, Booth JN, 3rd, Tanner RM .
Prevalence of masked hypertension and its association with subclinical cardiovascular disease in African Americans: results from the Jackson Heart Study.
J Am Heart Assoc 2016 Mar 29;5(3):e002284. doi: 10.1161/jaha.115.002284.
.
.
Keywords: Blood Pressure, Heart Disease and Health, Cardiovascular Conditions, Racial and Ethnic Minorities
Brown JR, Rezaee ME, Nichols EL
Incidence and in-hospital mortality of acute kidney injury (AKI) and dialysis-requiring AKI (AKI-D) after cardiac catheterization in the National Inpatient Sample.
This study examined cardiac catheterization or percutaneous coronary intervention (PCI) hospital discharges from the nationally representative National Inpatient Sample to determine annual population incidence rates for AKI and AKI-D in the United States from 2001 to 2011. It found that the incidence of AKI among cardiac catheterization and PCI patients has increased sharply in the United States; however, mortality has significantly declined.
AHRQ-funded; HS018443.
Citation: Brown JR, Rezaee ME, Nichols EL .
Incidence and in-hospital mortality of acute kidney injury (AKI) and dialysis-requiring AKI (AKI-D) after cardiac catheterization in the National Inpatient Sample.
J Am Heart Assoc 2016 Mar 15;5(3):e002739. doi: 10.1161/jaha.115.002739.
.
.
Keywords: Healthcare Cost and Utilization Project (HCUP), Adverse Events, Mortality, Patient Safety, Surgery, Heart Disease and Health, Cardiovascular Conditions, Kidney Disease and Health, Dialysis, Hospitals
Silverberg JI
Atopic disease and cardiovascular risk factors in US children.
The researcher examined the impact of atopic disease on cardiovascular risk in children. He found that in multivariable models, pediatric asthma and hay fever were associated with higher odds of overweight and obesity, hypertension, and hyperlipidemia, but not diabetes. However, eczema was associated with higher odds of overweight and obesity, but not hypertension, hyperlipidemia, or diabetes.
AHRQ-funded; HS023011.
Citation: Silverberg JI .
Atopic disease and cardiovascular risk factors in US children.
J Allergy Clin Immunol 2016 Mar;137(3):938-40.e1. doi: 10.1016/j.jaci.2015.09.012.
.
.
Keywords: Cardiovascular Conditions, Risk, Children/Adolescents, Children/Adolescents, Children/Adolescents
Vora AN, Peterson ED, Hellkamp AS
Care transitions after acute myocardial infarction for transferred-in versus direct-arrival patients.
Many patients in the United States require transfer from one hospital to another for acute myocardial infarction (MI) care. How well these transferred-in patients are transitioned back to their local community is unknown. This study found that transferred-in patients with acute MI are less likely to have outpatient clinic follow-up within 30 days and more likely to be readmitted within the first 30 days post discharge compared with direct-arrival patients.
AHRQ-funded; HS021092.
Citation: Vora AN, Peterson ED, Hellkamp AS .
Care transitions after acute myocardial infarction for transferred-in versus direct-arrival patients.
Circ Cardiovasc Qual Outcomes 2016 Mar;9(2):109-16. doi: 10.1161/circoutcomes.115.002108.
.
.
Keywords: Transitions of Care, Hospital Readmissions, Cardiovascular Conditions, Patient-Centered Outcomes Research, Hospital Discharge
Baik SH, Hernandez I, Zhang Y
Evaluating the initiation of novel oral anticoagulants in Medicare beneficiaries.
This study evaluated how patient demographics, clinical characteristics, types of insurance, and patient out-of-pocket spending affect the initiation of warfarin and 2 novel oral anticoagulants (NOACs)--dabigatran and rivaroxaban. It found that race, sex, type of Part D plans, and some clinical conditions were associated with the initiation of NOACs relative to warfarin.
AHRQ-funded; HS018657.
Citation: Baik SH, Hernandez I, Zhang Y .
Evaluating the initiation of novel oral anticoagulants in Medicare beneficiaries.
J Manag Care Spec Pharm 2016 Mar;22(3):281-92. doi: 10.18553/jmcp.2016.22.3.281.
.
.
Keywords: Blood Thinners, Medication, Heart Disease and Health, Cardiovascular Conditions, Social Determinants of Health
Newhall KA, Saunders EC, Larson RJ
Use of protamine for anticoagulation during carotid endarterectomy: a meta-analysis.
The researchers reviewed the evidence for and against protamine use at the conclusion of carotid endarterectomy (CEA), both in its association with increased thrombotic complications and with decreased bleeding. They concluded that based on available evidence, the use of protamine following CEA is associated with a reduction in bleeding complications, without increasing major thrombotic outcomes, including stroke, myocardial infarction, or death.
AHRQ-funded; HS021581.
Citation: Newhall KA, Saunders EC, Larson RJ .
Use of protamine for anticoagulation during carotid endarterectomy: a meta-analysis.
JAMA Surg 2016 Mar;151(3):247-55. doi: 10.1001/jamasurg.2015.3592.
.
.
Keywords: Medication, Adverse Drug Events (ADE), Registries, Cardiovascular Conditions
Bhatia N, Santos M, Jones LW
Cardiovascular effects of androgen deprivation therapy for the treatment of prostate cancer: ABCDE steps to reduce cardiovascular disease in patients with prostate cancer.
Since cardiovascular disease risk may be increased by the use of androgen deprivation therapy (ADT), the researchers have adapted the five-step "ABCDE" algorithm for prostate cancer survivors. Its treatment recommendations come under the following headings: awareness and aspirin, blood pressure, cholesterol and cigarettes, diet and diabetes, and exercise. The algorithm is illustrated by a hypothetical case study.
AHRQ-funded; HS022990.
Citation: Bhatia N, Santos M, Jones LW .
Cardiovascular effects of androgen deprivation therapy for the treatment of prostate cancer: ABCDE steps to reduce cardiovascular disease in patients with prostate cancer.
Circulation 2016 Feb 2;133(5):537-41. doi: 10.1161/circulationaha.115.012519.
.
.
Keywords: Cardiovascular Conditions, Cancer: Prostate Cancer, Diagnostic Safety and Quality, Medication, Patient-Centered Outcomes Research
Navarro-Millan I, Yang S, DuVall SL
Association of hyperlipidaemia, inflammation and serological status and coronary heart disease among patients with rheumatoid arthritis: data from the National Veterans Health Administration.
The researchers studied the association of serum lipids, inflammation, and seropositivity on coronary heart disease (CHD) and stroke in patients with rheumatoid arthritis. They found that in the study population of predominantly male veterans, higher levels of erythrocyte sedimentation rate and C-reactive protein were associated with increased risk of heart attack and stroke, and higher levels of HDL-C were inversely associated with heart attack and stroke.
AHRQ-funded; HS018517
Citation: Navarro-Millan I, Yang S, DuVall SL .
Association of hyperlipidaemia, inflammation and serological status and coronary heart disease among patients with rheumatoid arthritis: data from the National Veterans Health Administration.
Ann Rheum Dis. 2016 Feb;75(2):341-7. doi: 10.1136/annrheumdis-2013-204987..
Keywords: Stroke, Cardiovascular Conditions, Arthritis
Irvin VL, Kaplan RM
AHRQ Author: Kaplan RM
Effect sizes and primary outcomes in large-budget, cardiovascular-related behavioral randomized controlled trials funded by NIH since 1980.
The authors reviewed large-budget, National Institutes of Health (NIH)-supported randomized controlled trials (RCTs) with behavioral interventions to assess (1) publication rates, (2) trial registration, (3) use of objective measures, (4) significant behavior and physiological change, and (5) effect sizes. They concludedc that behavioral trials complied with trial registration standards. Most reported a physiological benefit, but few documented morbidity or mortality benefits.
AHRQ-authored.
Citation: Irvin VL, Kaplan RM .
Effect sizes and primary outcomes in large-budget, cardiovascular-related behavioral randomized controlled trials funded by NIH since 1980.
Ann Behav Med 2016 Feb;50(1):130-46. doi: 10.1007/s12160-015-9739-7.
.
.
Keywords: Outcomes, Cardiovascular Conditions, Research Methodologies, Behavioral Health
Lafata JE, Karter AJ, O'Connor PJ
Medication adherence does not explain black-white differences in cardiometabolic risk factor control among insured patients with diabetes.
The researchers examined whether medication adherence, controlling for treatment intensification, could explain differences in risk factor control between black and white patients with diabetes. They found poorer medication adherence among black patients than white patients. They concluded that medication adherence failed to explain observed racial differences in the achievement of HbA1c, LDL-C, and SBP control among insured patients with diabetes.
AHRQ-funded; HS019859.
Citation: Lafata JE, Karter AJ, O'Connor PJ .
Medication adherence does not explain black-white differences in cardiometabolic risk factor control among insured patients with diabetes.
J Gen Intern Med 2016 Feb;31(2):188-95. doi: 10.1007/s11606-015-3486-0.
.
.
Keywords: Cardiovascular Conditions, Diabetes, Medication, Patient Adherence/Compliance, Racial and Ethnic Minorities
Meischke H, Painter I, Turner AM
Protocol: simulation training to improve 9-1-1 dispatcher identification of cardiac arrest.
The researchers aim to evaluate the use of phone-based standardized patient simulation training to improve identification of the need for Telephone-CPR (T-CPR) and shorten time to start of T-CPR instructions. They specify that the STAT-911 study will evaluate if over-the-phone simulation training with standardized patients can improve 9-1-1 dispatchers' ability identify the need for, and promptly begin T-CPR.
AHRQ-funded; HS021658.
Citation: Meischke H, Painter I, Turner AM .
Protocol: simulation training to improve 9-1-1 dispatcher identification of cardiac arrest.
BMC Emerg Med 2016 Feb 1;16:9. doi: 10.1186/s12873-016-0073-6.
.
.
Keywords: Cardiovascular Conditions, Emergency Medical Services (EMS), Patient Safety, Training
Epps KC, Holper EM, Selzer F
Sex differences in outcomes following percutaneous coronary intervention according to age.
Women <50 years of age with coronary artery disease may represent a group at higher risk for recurrent ischemic events after percutaneous coronary intervention (PCI); however, no long-term, multicenter outcomes assessment exists in this population. This study found that, compared with older women, younger women remained at increased risk of major adverse cardiovascular events, whereas all outcome rates were similar in older women and men.
AHRQ-funded; HS000009.
Citation: Epps KC, Holper EM, Selzer F .
Sex differences in outcomes following percutaneous coronary intervention according to age.
Circ Cardiovasc Qual Outcomes 2016 Feb;9(2 Suppl 1):S16-25. doi: 10.1161/circoutcomes.115.002482.
.
.
Keywords: Women, Heart Disease and Health, Outcomes, Adverse Events, Cardiovascular Conditions
Ladapo JA, Blecker S, Douglas PS
Appropriateness of cardiac stress test use among primary care physicians and cardiologists in the United States.
In this study, the researchers used nationally-representative data to examine differences in appropriate use of cardiac stress testing between cardiologists and primary care physicians (PCPs) in the US. Using permissive criteria to determine appropriateness, they found that primary care physicians are more likely to order or perform a rarely appropriate cardiac stress test than cardiologists.
AHRQ-funded; HS023683.
Citation: Ladapo JA, Blecker S, Douglas PS .
Appropriateness of cardiac stress test use among primary care physicians and cardiologists in the United States.
Int J Cardiol 2016 Jan 15;203:584-6. doi: 10.1016/j.ijcard.2015.10.238.
.
.
Keywords: Cardiovascular Conditions, Diagnostic Safety and Quality, Imaging, Primary Care, Shared Decision Making
Booth JN, 3rd, Redmond N, Sims M
The association of reduced lung function with blood pressure variability in African Americans: data from the Jackson Heart Study.
The reseaerchers evaluated the association between percent predicted lung-function and 24-hour blood pressure variability (BPV) in 1008 African Americans enrolled in the Jackson Heart Study who underwent ambulatory blood pressure (BP) monitoring. They found that lung-function was not associated with increased 24-hour BPV.
AHRQ-funded; HS023009.
Citation: Booth JN, 3rd, Redmond N, Sims M .
The association of reduced lung function with blood pressure variability in African Americans: data from the Jackson Heart Study.
BMC Cardiovasc Disord 2016 Jan 12;16:6. doi: 10.1186/s12872-015-0182-2.
.
.
Keywords: Cardiovascular Conditions, Blood Pressure, Racial and Ethnic Minorities, Risk, Respiratory Conditions
Brown DW, Mangeot C, Anderson JB
Digoxin use is associated with reduced interstage mortality in patients with no history of arrhythmia after stage I palliation for single ventricle heart disease.
The researchers sought to determine whether digoxin use post-S1P is associated with reduced interstage mortality (IM), utilizing the multicenter database of the National Pediatric Cardiology Quality Improvement Collaborative (NPCQIC). They found that among infants with single vetricle defects in the NPCQIC database discharged post-S1P with no history of arrhythmia, use of digoxin at discharge was associated with reduced IM.
AHRQ-funded; HS021114.
Citation: Brown DW, Mangeot C, Anderson JB .
Digoxin use is associated with reduced interstage mortality in patients with no history of arrhythmia after stage I palliation for single ventricle heart disease.
J Am Heart Assoc 2016 Jan 11;5(1). doi: 10.1161/jaha.115.002376.
.
.
Keywords: Medication, Mortality, Cardiovascular Conditions, Patient-Centered Outcomes Research
Newhall K, Spangler E, Dzebisashvili N
Amputation rates for patients with diabetes and peripheral arterial disease: the effects of race and region.
The authors examined national trends in care of patients with both peripheral artery disease (PAD) and diabetes. They found that the prevalence of concurrent PAD and diabetes is increasing, but amputation rates and amputation-free survival vary significantly by both race and hospital referral region.
AHRQ-funded; HS021581.
Citation: Newhall K, Spangler E, Dzebisashvili N .
Amputation rates for patients with diabetes and peripheral arterial disease: the effects of race and region.
Ann Vasc Surg 2016 Jan;30:292-8.e1. doi: 10.1016/j.avsg.2015.07.040.
.
.
Keywords: Cardiovascular Conditions, Diabetes, Elderly, Racial and Ethnic Minorities, Outcomes
Cummings DM, Kirian K, Howard G
Consequences of comorbidity of elevated stress and/or depressive symptoms and incident cardiovascular outcomes in diabetes: results from the REasons for Geographic And Racial Differences in Stroke (REGARDS) study.
The authors evaluated the impact of comorbid depressive symptoms and/or stress on adverse cardiovascular (CV) outcomes in individuals with diabetes compared with those without diabetes. They concluded that comorbid stress and/or depressive symptoms are common in individuals with diabetes and together are associated with progressively increased risks for adverse CV outcomes.
AHRQ-funded; HS023009.
Citation: Cummings DM, Kirian K, Howard G .
Consequences of comorbidity of elevated stress and/or depressive symptoms and incident cardiovascular outcomes in diabetes: results from the REasons for Geographic And Racial Differences in Stroke (REGARDS) study.
Diabetes Care 2016 Jan;39(1):101-9. doi: 10.2337/dc15-1174.
.
.
Keywords: Cardiovascular Conditions, Depression, Diabetes, Patient-Centered Outcomes Research, Stress
Killian JT, Holcomb CN, Graham LA
Delays in surgery for patients with coronary stents placed after diagnosis of colorectal cancer.
The researchers sought to determine whether the presence of a coronary stent affected the timing of colorectal cancer resection and the postoperative outcomes. They found that the median time from diagnosis to surgery was 100 days for patients who received a stent after a colonoscopy and 42 days for patients whose stent was present at the time of the colonoscopy.
AHRQ-funded; HS013852.
Citation: Killian JT, Holcomb CN, Graham LA .
Delays in surgery for patients with coronary stents placed after diagnosis of colorectal cancer.
JAMA Surg 2016 Jan;151(1):86-8. doi: 10.1001/jamasurg.2015.3130..
Keywords: Cancer: Colorectal Cancer, Cardiovascular Conditions, Colonoscopy, Heart Disease and Health, Surgery
Patel R, Lim RP, Saric M
Diagnostic performance of cardiac magnetic resonance imaging and echocardiography in evaluation of cardiac and paracardiac masses.
The researchers evaluated the predictive value of echocardiography and cardiac magnetic resonance (CMR) imaging parameters to identify tumors and malignancy and to provide histopathologic diagnosis of cardiac masses. They found that CMR identified 6 masses missed on transthoracic echocardiography (4 of which were outside the heart) and provided significantly more correct histopathologic diagnoses compared to echocardiography (77 percent vs 43 percent).
AHRQ-funded; HS019473.
Citation: Patel R, Lim RP, Saric M .
Diagnostic performance of cardiac magnetic resonance imaging and echocardiography in evaluation of cardiac and paracardiac masses.
Am J Cardiol 2016 Jan;117(1):135-40. doi: 10.1016/j.amjcard.2015.10.014..
Keywords: Diagnostic Safety and Quality, Cardiovascular Conditions, Imaging, Cancer, Comparative Effectiveness
Garcia-Albeniz X, Hsu J, Lipsitch M
Infective endocarditis and cancer in the elderly.
The researchers investigated the magnitude of the association between infective endocarditis and cancer, and the natural history of cancer patients with concomitant diagnosis of infective endocarditis. They found that in this elderly population, the incidence of infective endocarditis around a colorectal cancer diagnosis was substantially higher than around the diagnosis of lung, breast and prostate cancers.
AHRQ-funded; HS023128.
Citation: Garcia-Albeniz X, Hsu J, Lipsitch M .
Infective endocarditis and cancer in the elderly.
Eur J Epidemiol 2016 Jan;31(1):41-9. doi: 10.1007/s10654-015-0111-9.
.
.
Keywords: Cancer, Cancer: Colorectal Cancer, Cardiovascular Conditions, Elderly, Cancer: Prostate Cancer
Patorno E, Wang SV, Schneeweiss S
Initiation patterns of statin therapy among adult patients undergoing intermediate to high-risk non-cardiac surgery.
The researchers examined patterns of perioperative statin initiation among adults undergoing non-cardiac elective surgery in the USA. They found that, despite the lack of robust evidence, perioperative statin initiation progressively increased from 2003 to 2012, particularly among patients undergoing major vascular surgery. They concluded that these trends were largely attributable to the initiation of statins in anticipation of non-cardiac surgery rather than routine dyslipidemia treatment.
AHRQ-funded; HS022193.
Citation: Patorno E, Wang SV, Schneeweiss S .
Initiation patterns of statin therapy among adult patients undergoing intermediate to high-risk non-cardiac surgery.
Pharmacoepidemiol Drug Saf 2016 Jan;25(1):64-72. doi: 10.1002/pds.3892.
.
.
Keywords: Cardiovascular Conditions, Medication, Prevention, Surgery
Wallaert JB, Nolan BW, Stone DH
Physician specialty and variation in carotid revascularization technique selected for Medicare patients.
The researchers investigated whether the choice of carotid artery stenting (CAS) vs. carotid endarterectomy (CEA) varies as a function of treating physician specialty, which would result in regional variation in the relative use of these treatment types They found that the proportion of all carotid revascularization procedures performed as CAS varies markedly by geographic region, and regions with the highest proportion of cardiologists perform the most CAS procedures.
AHRQ-funded; HS021581.
Citation: Wallaert JB, Nolan BW, Stone DH .
Physician specialty and variation in carotid revascularization technique selected for Medicare patients.
J Vasc Surg 2016 Jan;63(1):89-97. doi: 10.1016/j.jvs.2015.08.068.
.
.
Keywords: Heart Disease and Health, Medicare, Cardiovascular Conditions, Disparities, Outcomes