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Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
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1 to 1 of 1 Research Studies DisplayedChen Y, Liu Y, Chu H
A simple and robust method for multivariate meta-analysis of diagnostic test accuracy.
The recently proposed trivariate generalized linear mixed-effects models are only applicable to cohort studies, and more importantly, they assume a common correlation structure across studies and trivariate normality on disease prevalence, test sensitivity, and specificity after transformation by some pre-specified link functions. In this paper, the authors evaluate the performance of the commonly used random-effects model under violations of these assumptions and propose a simple and robust method to fully utilize the information contained in case-control and cohort studies.
AHRQ-funded; HS022900; HS020666.
Citation: Chen Y, Liu Y, Chu H .
A simple and robust method for multivariate meta-analysis of diagnostic test accuracy.
Stat Med 2017 Jan 15;36(1):105-21. doi: 10.1002/sim.7093.
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Keywords: Diagnostic Safety and Quality, Research Methodologies