National Healthcare Quality and Disparities Report
Latest available findings on quality of and access to health care
Data
- Data Infographics
- Data Visualizations
- Data Tools
- Data Innovations
- All-Payer Claims Database
- Healthcare Cost and Utilization Project (HCUP)
- Medical Expenditure Panel Survey (MEPS)
- AHRQ Quality Indicator Tools for Data Analytics
- State Snapshots
- United States Health Information Knowledgebase (USHIK)
- Data Sources Available from AHRQ
Search All Research Studies
AHRQ Research Studies Date
Topics
- Adverse Drug Events (ADE) (1)
- Antibiotics (1)
- Behavioral Health (1)
- Cardiovascular Conditions (2)
- Children/Adolescents (3)
- Chronic Conditions (2)
- Community-Acquired Infections (1)
- Comparative Effectiveness (1)
- Data (1)
- Diagnostic Safety and Quality (2)
- Elderly (1)
- Evidence-Based Practice (1)
- Guidelines (1)
- Healthcare Cost and Utilization Project (HCUP) (5)
- Healthcare Costs (2)
- Health Insurance (1)
- Hospitalization (3)
- Medicare (1)
- Medication (1)
- Nutrition (1)
- Pain (1)
- Patient-Centered Outcomes Research (3)
- Patient Experience (1)
- Patient Safety (1)
- Prevention (1)
- Quality Measures (1)
- Quality of Life (3)
- Risk (2)
- (-) Skin Conditions (17)
AHRQ Research Studies
Sign up: AHRQ Research Studies Email updates
Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 17 of 17 Research Studies DisplayedKwa MC, Silverberg JI
Association between inflammatory skin disease and cardiovascular and cerebrovascular co-morbidities in US adults: analysis of Nationwide Inpatient Sample data.
The objective of this study was to determine whether these inflammatory skin diseases are associated with increased cardiovascular/cerebrovascular risk and/or disease. It concluded that atopic dermatitis or eczema (AD-E), pemphigus, bullous pemphigoid (BP), and hidradenitis were all associated with increased cardiovascular and cerebrovascular risk, especially at younger age.
AHRQ-funded; HS023011.
Citation: Kwa MC, Silverberg JI .
Association between inflammatory skin disease and cardiovascular and cerebrovascular co-morbidities in US adults: analysis of Nationwide Inpatient Sample data.
Am J Clin Dermatol 2017 Dec;18(6):813-23. doi: 10.1007/s40257-017-0293-x.
.
.
Keywords: Cardiovascular Conditions, Healthcare Cost and Utilization Project (HCUP), Risk, Skin Conditions
Vakharia PP, Chopra R, Sacotte R
Burden of skin pain in atopic dermatitis.
This study sought to characterize the patient burden of skin pain in AD. It found that twenty-four (16.8 percent) patients thought the skin pain was part of their itch, 16 (11.2 percent) from scratching, and 77 (72.0 percent) from both. Patients with skin pain were more likely to describe their itch using terms that resembled neuropathic pain.
AHRQ-funded; HS023011.
Citation: Vakharia PP, Chopra R, Sacotte R .
Burden of skin pain in atopic dermatitis.
Ann Allergy Asthma Immunol 2017 Dec;119(6):548-52.e3. doi: 10.1016/j.anai.2017.09.076.
.
.
Keywords: Chronic Conditions, Pain, Quality of Life, Skin Conditions
Kwa L, Kwa MC, Silverberg JI
Cardiovascular comorbidities of pediatric psoriasis among hospitalized children in the United States.
This study sought to determine if there is an association between pediatric psoriasis and cardiovascular comorbidities. It found that in multivariate survey logistic regression models adjusting for age, sex, and race/ethnicity, pediatric psoriasis was significantly associated with 5 of 10 cardiovascular comorbidities.
AHRQ-funded; HS023011.
Citation: Kwa L, Kwa MC, Silverberg JI .
Cardiovascular comorbidities of pediatric psoriasis among hospitalized children in the United States.
J Am Acad Dermatol 2017 Dec;77(6):1023-29. doi: 10.1016/j.jaad.2017.08.034.
.
.
Keywords: Cardiovascular Conditions, Children/Adolescents, Healthcare Cost and Utilization Project (HCUP), Hospitalization, Skin Conditions
Chopra R, Vakharia PP, Sacotte R
Relationship between EASI and SCORAD severity assessments for atopic dermatitis.
This research letter discussed the relationship between Eczema Area and Severity Index (EASI) and Scoring AD (SOCRAD) severity assessments for atopic dermatitis. The investigators performed a prospective, dermatology practice–based, observational study to determine the relationship between EASI and SCORAD.
AHRQ-funded; HS023011.
Citation: Chopra R, Vakharia PP, Sacotte R .
Relationship between EASI and SCORAD severity assessments for atopic dermatitis.
J Allergy Clin Immunol 2017 Dec;140(6):1708-10.e1. doi: 10.1016/j.jaci.2017.04.052.
.
.
Keywords: Skin Conditions
Chopra R, Vakharia PP, Sacotte R
Efficacy of bleach baths in reducing severity of atopic dermatitis: a systematic review and meta-analysis.
This study sought to determine the efficacy of bleach vs water baths at decreasing atopic dermatitis (AD) severity. In pooled analyses, there were no significant differences observed between bleach vs water baths at 4 weeks vs baseline for the Eczema Area and Severity Index. Although bleach baths are effective in decreasing AD severity, they do not appear to be more effective than water baths alone.
AHRQ-funded; HS023011.
Citation: Chopra R, Vakharia PP, Sacotte R .
Efficacy of bleach baths in reducing severity of atopic dermatitis: a systematic review and meta-analysis.
Ann Allergy Asthma Immunol 2017 Nov;119(5):435-40. doi: 10.1016/j.anai.2017.08.289.
.
.
Keywords: Comparative Effectiveness, Patient-Centered Outcomes Research, Skin Conditions
Gianfrancesco MA, Schmajuk G, Haserodt S
Hydroxychloroquine dosing in immune-mediated diseases: implications for patient safety.
Evidence suggests that hydroxychloroquine (HCQ) retinal toxicity is more common than previously thought. Adhering to careful weight-based dosing can significantly reduce the risk of this adverse event and is recommended in recent guidelines. The study authors used electronic health record data from a large health system to examine HCQ dosing over a 5-year period and identify risk factors associated with higher dosage of HCQ.
AHRQ-funded; HS024412.
Citation: Gianfrancesco MA, Schmajuk G, Haserodt S .
Hydroxychloroquine dosing in immune-mediated diseases: implications for patient safety.
Rheumatol Int 2017 Oct;37(10):1611-18. doi: 10.1007/s00296-017-3782-6..
Keywords: Adverse Drug Events (ADE), Patient Safety, Risk, Skin Conditions
Kwa MC, Ardalan K, Laumann AE
Predictors of hospitalization, length of stay and costs of care among adults with dermatomyositis in the United States.
The researchers sought to determine the prevalence and risk factors for hospitalization with dermatomyositis and to assess inpatient burden of dermatomyositis. They concluded that there is a significant and increasing inpatient burden for dermatomyositis in the US. Also, there appear to be racial differences as non-whites have higher prevalence of admission, increased length of stay and cost of care.
AHRQ-funded; HS023011.
Citation: Kwa MC, Ardalan K, Laumann AE .
Predictors of hospitalization, length of stay and costs of care among adults with dermatomyositis in the United States.
Arthritis Care Res 2017 Sep;69(9):1391-99. doi: 10.1002/acr.23190.
.
.
Keywords: Healthcare Cost and Utilization Project (HCUP), Hospitalization, Health Insurance, Skin Conditions
Zhang M, Silverberg JI, Kaffenberger BH
Prescription patterns and costs of acne/rosacea medications in Medicare patients vary by prescriber specialty.
The researchers described the medications used for treating acne/rosacea in the Medicare population and evaluated differences in costs between specialties. They concluded that costs of prescriptions for acne/rosacea from specialists are higher than those from primary care physicians and could be reduced by choosing generic and less expensive options.
AHRQ-funded; HS023011.
Citation: Zhang M, Silverberg JI, Kaffenberger BH .
Prescription patterns and costs of acne/rosacea medications in Medicare patients vary by prescriber specialty.
J Am Acad Dermatol 2017 Sep;77(3):448-55.e2. doi: 10.1016/j.jaad.2017.04.1127.
.
.
Keywords: Medication, Skin Conditions, Healthcare Costs, Medicare, Elderly
Greenhawt M, Fleischer DM, Chan ES
LEAPing through the looking glass: secondary analysis of the effect of skin test size and age of introduction on peanut tolerance after early peanut introduction.
This study explored relationships between peanut tolerance, baseline peanut/egg sensitization, eczema severity/duration, age of introduction, gender, and race. It concluded that increasing peanut wheal size predicted peanut tolerance only in the avoidance arm. Peanut introduction between 6 and 11 months of age was associated with the highest rates of peanut tolerance, questioning the 'urgency' of introduction before 6 months.
AHRQ-funded; HS024599.
Citation: Greenhawt M, Fleischer DM, Chan ES .
LEAPing through the looking glass: secondary analysis of the effect of skin test size and age of introduction on peanut tolerance after early peanut introduction.
Allergy 2017 Aug;72(8):1254-60. doi: 10.1111/all.13100.
.
.
Keywords: Evidence-Based Practice, Nutrition, Skin Conditions, Patient-Centered Outcomes Research
Narla S, Hsu DY, Thyssen JP
Inpatient financial burden of atopic dermatitis in the United States.
Little is known about the inpatient burden of atopic dermatitis (AD). The researchers sought to determine some risk factors and financial-burden of hospitalizations for AD in the US. They found that the high prevalence of hospitalization resulted in total inpatient costs of $8,288,083 per-year for adults and $3,333,868 per-year for children. In conclusion, there is a substantial inpatient financial-burden of AD in the US.
AHRQ-funded; HS023011.
Citation: Narla S, Hsu DY, Thyssen JP .
Inpatient financial burden of atopic dermatitis in the United States.
J Invest Dermatol 2017 Jul;137(7):1461-67. doi: 10.1016/j.jid.2017.02.975.
.
.
Keywords: Healthcare Cost and Utilization Project (HCUP), Skin Conditions, Healthcare Costs, Hospitalization
Silverberg JI
Selected comorbidities of atopic dermatitis: atopy, neuropsychiatric, and musculoskeletal disorders.
Atopic dermatitis (AD) is a chronic pruritic inflammatory skin disease with substantial morbidity and quality of life impairment. This review summarizes recent developments in the atopic and neuropsychiatric comorbidities of AD. For example, it concludes that persons with AD appear to be at higher risk for multiple neuropsychiatric disorders, including depression, attention-deficit/hyperactivity disorder, speech disorders in childhood, headaches, and seizures.
AHRQ-funded; HS023011.
Citation: Silverberg JI .
Selected comorbidities of atopic dermatitis: atopy, neuropsychiatric, and musculoskeletal disorders.
Clin Dermatol 2017 Jul - Aug;35(4):360-66. doi: 10.1016/j.clindermatol.2017.03.008.
.
.
Keywords: Skin Conditions, Chronic Conditions, Behavioral Health, Quality of Life, Children/Adolescents
Hsu DY, Dalal P, Sable KA
Validation of International Classification of Disease Ninth Revision codes for atopic dermatitis.
This study sought to validate the use of ICD-9-CM codes for identifying atopic dermatitis. It found that in the outpatient setting, the ICD-9-CM codes 691.8 and 692.9 alone have poor positive predictive value (PPV). Incorporation of diagnoses of asthma, hay fever, and food allergy improves PPV and specificity. In the inpatient setting, a primary discharge diagnosis of 691.8 had excellent PPV.
AHRQ-funded; HS023011.
Citation: Hsu DY, Dalal P, Sable KA .
Validation of International Classification of Disease Ninth Revision codes for atopic dermatitis.
Allergy 2017 Jul;72(7):1091-95. doi: 10.1111/all.13113.
.
.
Keywords: Data, Diagnostic Safety and Quality, Skin Conditions
Daum RS, Miller LG, Immergluck L
A placebo-controlled trial of antibiotics for smaller skin abscesses.
The authors evaluated the appropriate management of uncomplicated skin abscesses in the era of community-associated methicillin-resistant Staphylococcus aureus (MRSA). They concluded that, compared with incision and drainage alone, clindamycin or TMP-SMX in conjunction with incision and drainage improves short-term outcomes in patients who have a simple abscess. This benefit must be weighed against the known side-effect profile of these antimicrobials.
AHRQ-funded; HS024338.
Citation: Daum RS, Miller LG, Immergluck L .
A placebo-controlled trial of antibiotics for smaller skin abscesses.
N Engl J Med 2017 Jun 29;376(26):2545-55. doi: 10.1056/NEJMoa1607033.
.
.
Keywords: Antibiotics, Community-Acquired Infections, Skin Conditions
Hsu DY, Brieva J, Silverberg NB
Pediatric Stevens-Johnson syndrome and toxic epidermal necrolysis in the United States.
In this study, the investigators sought to determine the morbidity, mortality, and comorbid health conditions of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in US children. They found that the incidences of SJS, SJS-TEN, and TEN were a mean 5.3, 0.8, and 0.4 cases per million children per year in the US, respectively.The investigators concluded that pediatric SJS/TEN poses a substantial health burden in the United States.
AHRQ-funded; HS023011.
Citation: Hsu DY, Brieva J, Silverberg NB .
Pediatric Stevens-Johnson syndrome and toxic epidermal necrolysis in the United States.
J Am Acad Dermatol 2017 May;76(5):811-17.e4. doi: 10.1016/j.jaad.2016.12.024..
Keywords: Children/Adolescents, Healthcare Cost and Utilization Project (HCUP), Skin Conditions
Kwa MC, Ardalan K, Laumann AE
Validation of International Classification of Diseases codes for the epidemiologic study of dermatomyositis.
The authors assessed the validity of using ICD-9-CM code 710.3 to identify adult patients with dermatomyositis in outpatient and inpatient settings. They found that one or more occurrences of ICD-9 code 710.3 is insufficient to support the diagnosis of dermatomyositis in the outpatient setting, but that ICD-9 710.3 codes appear to be valid in the inpatient setting.
AHRQ-funded; HS023011.
Citation: Kwa MC, Ardalan K, Laumann AE .
Validation of International Classification of Diseases codes for the epidemiologic study of dermatomyositis.
Arthritis Care Res 2017 May;69(5):753-57. doi: 10.1002/acr.23010.
.
.
Keywords: Diagnostic Safety and Quality, Patient-Centered Outcomes Research, Skin Conditions
Sisic M, Kirby JS, Boyal S
Development of a quality-of-life measure for hidradenitis suppurativa.
The objective of this study was to develop a QoL instrument for hidradenitis suppurativa (HS-QoL) in accordance with recommended standards. : Concept elicitation interviews with patients with HS generated 12 themes. Most frequently reported were impacts on daily activities and symptoms due to HS. These themes, along with literature review and input from clinical experts, informed development of the HS-QoL-v1.
AHRQ-funded; HS024585.
Citation: Sisic M, Kirby JS, Boyal S .
Development of a quality-of-life measure for hidradenitis suppurativa.
J Cutan Med Surg 2017 Mar/Apr;21(2):152-55. doi: 10.1177/1203475416677721.
.
.
Keywords: Patient Experience, Quality Measures, Quality of Life, Skin Conditions
Togias A, Cooper SF, Acebal ML
Addendum guidelines for the prevention of peanut allergy in the United States: report of the National Institute of Allergy and Infectious Diseases-sponsored expert panel.
Along with 25 professional organizations, federal agencies, and patient advocacy groups, the National Institute of Allergy and Infectious Diseases facilitated development of addendum guidelines to specifically address the prevention of peanut allergy. This addendum provides 3 separate guidelines for infants at various risk levels for the development of peanut allergy and is intended for use by a wide variety of health care providers.
AHRQ-funded; HS024599.
Citation: Togias A, Cooper SF, Acebal ML .
Addendum guidelines for the prevention of peanut allergy in the United States: report of the National Institute of Allergy and Infectious Diseases-sponsored expert panel.
J Allergy Clin Immunol 2017 Jan;139(1):29-44. doi: 10.1016/j.jaci.2016.10.010.
.
.
Keywords: Guidelines, Prevention, Skin Conditions