National Healthcare Quality and Disparities Report
Latest available findings on quality of and access to health care
Data
- Data Infographics
- Data Visualizations
- Data Tools
- Data Innovations
- All-Payer Claims Database
- Healthcare Cost and Utilization Project (HCUP)
- Medical Expenditure Panel Survey (MEPS)
- AHRQ Quality Indicator Tools for Data Analytics
- State Snapshots
- United States Health Information Knowledgebase (USHIK)
- Data Sources Available from AHRQ
Search All Research Studies
AHRQ Research Studies Date
Topics
- Back Health and Pain (1)
- Blood Clots (1)
- Blood Thinners (1)
- Cardiovascular Conditions (1)
- Chronic Conditions (1)
- Comparative Effectiveness (1)
- Elderly (1)
- Evidence-Based Practice (3)
- Health Services Research (HSR) (1)
- Heart Disease and Health (1)
- Medication (1)
- Pain (1)
- Patient-Centered Healthcare (1)
- (-) Patient-Centered Outcomes Research (9)
- Patient and Family Engagement (1)
- Primary Care (1)
- (-) Research Methodologies (9)
- Skin Conditions (1)
AHRQ Research Studies
Sign up: AHRQ Research Studies Email updates
Research Studies is a compilation of published research articles funded by AHRQ or authored by AHRQ researchers.
Results
1 to 9 of 9 Research Studies DisplayedNayfe R, Chansard M, Hynan LS
Comparison of patient-reported outcomes measurement information system and legacy instruments in multiple domains among older veterans with chronic back pain.
This study evaluated construct (convergent and discriminant) validity and time to complete NIH's Patient Reported Outcomes Measurement Information System (PROMIS) as compared to legacy instruments. Results showed that, given time efficiency of using PROMIS, along with strong construct validity, PROMIS instruments are a practical choice for measuring multidimensional patient-reported outcomes in older Veterans with chronic low back pain for both research and clinical purposes.
AHRQ-funded; HS022418.
Citation: Nayfe R, Chansard M, Hynan LS .
Comparison of patient-reported outcomes measurement information system and legacy instruments in multiple domains among older veterans with chronic back pain.
BMC Musculoskelet Disord 2020 Sep 8;21(1):598. doi: 10.1186/s12891-020-03587-6..
Keywords: Elderly, Back Health and Pain, Pain, Chronic Conditions, Patient-Centered Outcomes Research, Research Methodologies
Cuthel A, Rogers E, Daniel F
Barriers and facilitators in the recruitment and retention of more than 250 small independent primary care practices for EvidenceNOW.
This study examined barriers and facilitators in the recruitment and retention of small independent practices (SIPs) to participate in research studies. The authors used qualitative data from the HealthyHearts New York City program, part of the EvidenceNOW initiative. This randomized controlled trial took place from 2015 through 2018 across 5 boroughs in NYC. A total of 257 SIPs (<5 full-time clinicians) were recruited originally. The three main factors that facilitated rapid recruitment were: 1) a prior well-established relationship with the local health department; 2) alignment of project goals with practice priorities, and 3) having appropriate monetary incentives. Specific strategies that enhance recruitment of SIPS and fills gaps in knowledge about factors that influence retention are identified.
AHRQ-funded; HS023922.
Citation: Cuthel A, Rogers E, Daniel F .
Barriers and facilitators in the recruitment and retention of more than 250 small independent primary care practices for EvidenceNOW.
Am J Med Qual 2020 Sep/Oct;35(5):388-96. doi: 10.1177/1062860619893422..
Keywords: Primary Care, Evidence-Based Practice, Patient-Centered Outcomes Research, Research Methodologies
Silverberg JI, Lei D, Yousaf M
Comparison of Patient-Oriented Eczema Measure and Patient-Oriented Scoring Atopic Dermatitis vs Eczema Area and Severity Index and other measures of atopic dermatitis: a validation study.
Little is known about the measurement properties of Patient-Oriented Scoring Atopic Dermatitis (PO-SCORAD) in adults with atopic dermatitis (AD). Even less is known about how PO-SCORAD performs compared with the Patient-Oriented Eczema Measure (POEM). The purpose of this study was to examine the measurement properties of PO-SCORAD and compare them with those of POEM. The investigators concluded that PO-SCORAD and POEM had good construct and cross-cultural validity, reliability, and responsiveness in adults with AD and were feasible for use in clinical trials and practice.
AHRQ-funded; HS023011.
Citation: Silverberg JI, Lei D, Yousaf M .
Comparison of Patient-Oriented Eczema Measure and Patient-Oriented Scoring Atopic Dermatitis vs Eczema Area and Severity Index and other measures of atopic dermatitis: a validation study.
Ann Allergy Asthma Immunol 2020 Jul;125(1):78-83. doi: 10.1016/j.anai.2020.03.006..
Keywords: Skin Conditions, Research Methodologies, Patient-Centered Outcomes Research
Utter GH, Dhillon TS, Danielsen BH
Use of statewide administrative data to assess clinical outcomes: a retrospective cohort study of therapeutic anticoagulation for isolated calf vein thrombosis.
Single-center comparative effectiveness studies evaluating outcomes that can occur posthospitalization may become biased if outcomes diagnosed at other facilities are not ascertained. Administrative datasets that link patients' records across facilities may improve outcome ascertainment. The purpose of this study was to determine whether use of linked administrative data significantly augmented thromboembolic outcome ascertainment. The investigators concluded that use of linked hospital administrative data augmented detection of outcomes but imperfect linkage, nonspecific diagnoses, and documentation/coding errors introduced uncertainty regarding the accuracy of outcome ascertainment.
AHRQ-funded; HS022236.
Citation: Utter GH, Dhillon TS, Danielsen BH .
Use of statewide administrative data to assess clinical outcomes: a retrospective cohort study of therapeutic anticoagulation for isolated calf vein thrombosis.
Med Care 2020 Jul;58(7):658-62. doi: 10.1097/mlr.0000000000001347.
.
.
Keywords: Blood Clots, Blood Thinners, Medication, Research Methodologies, Patient-Centered Outcomes Research
Ahmad FS, Ricket IM, Hammill BG BG
Computable phenotype implementation for a national, multicenter pragmatic clinical trial: lessons learned from ADAPTABLE.
This methods paper provides an overview of the development and implementation of a computable phenotype in ADAPTABLE (Aspirin Dosing: a Patient-Centric Trial Assessing Benefits and Long-Term Effectiveness)--a pragmatic, randomized, open-label clinical trial testing the optimal dose of aspirin for secondary prevention of atherosclerotic cardiovascular disease events. Lessons learned included the following: the accuracy and utility of a computable phenotype are dependent on the quality of the source data; local validation and modification were required based on site factors; and sustained collaboration among a diverse team of researchers is needed during development and implementation. The ADAPTABLE computable phenotype served as an efficient method to recruit patients in a multisite pragmatic clinical trial.
AHRQ-funded; HS026385.
Citation: Ahmad FS, Ricket IM, Hammill BG BG .
Computable phenotype implementation for a national, multicenter pragmatic clinical trial: lessons learned from ADAPTABLE.
Circ Cardiovasc Qual Outcomes 2020 Jun;13(6):e006292. doi: 10.1161/circoutcomes.119.006292..
Keywords: Patient-Centered Outcomes Research, Research Methodologies, Heart Disease and Health, Cardiovascular Conditions
Tsou AY, Treadwell JR, Erinoff E
Machine learning for screening prioritization in systematic reviews: comparative performance of Abstrackr and EPPI-Reviewer.
Improving the speed of systematic review (SR) development is key to supporting evidence-based medicine. Machine learning tools which semi-automate citation screening might improve efficiency. Few studies have assessed use of screening prioritization functionality or compared two tools head to head. In this project, the investigators compared performance of two machine-learning tools for potential use in citation screening.
AHRQ-funded; HS025859.
Citation: Tsou AY, Treadwell JR, Erinoff E .
Machine learning for screening prioritization in systematic reviews: comparative performance of Abstrackr and EPPI-Reviewer.
Syst Rev 2020 Apr 2;9(1):73. doi: 10.1186/s13643-020-01324-7..
Keywords: Health Services Research (HSR), Research Methodologies, Evidence-Based Practice, Patient-Centered Outcomes Research
Toh S
Analytic and data sharing options in real-world multi-database studies of comparative effectiveness and safety of medical products.
A wide range of analytic and data sharing options are available in non-experimental multi-database studies designed to assess the real-world benefits and risks of medical products. This article reviewed available analytic and data sharing options and discussed key scientific and practical considerations when choosing among these options in multi-database studies of comparative effectiveness and safety of medical products.
AHRQ-funded; HS026214.
Citation: Toh S .
Analytic and data sharing options in real-world multi-database studies of comparative effectiveness and safety of medical products.
Clin Pharmacol Ther 2020 Apr;107(4):834-42. doi: 10.1002/cpt.1754..
Keywords: Patient-Centered Outcomes Research, Research Methodologies, Comparative Effectiveness
Taft L, Shen C
A non-parametric statistical test of null treatment effect in sub-populations.
Randomized clinical trials are designed to estimate the average treatment effect (ATE). If heterogeneity of treatment effect exists, then it is possible that there may be subjects who derive a treatment effect different from the ATE. In this study, the investigators propose a method to test the hypothesis that there exist subjects who derive benefit (or harm) against the null hypothesis that the treatment has no benefit (or harm) on each of the smallest sub-populations defined by discrete baseline covariates.
AHRQ-funded; HS024520.
Citation: Taft L, Shen C .
A non-parametric statistical test of null treatment effect in sub-populations.
J Biopharm Stat 2020 Mar;30(2):277-93. doi: 10.1080/10543406.2019.1636810..
Keywords: Research Methodologies, Patient-Centered Outcomes Research
Byham-Gray LD, Peters EN, Rothpletz-Puglia P
Patient-centered model for protein-energy wasting: stakeholder deliberative panels.
Integrating the patient's voice into research prioritization is essential for solving problems that patients care the most about in terms of health, symptom management, and survival. In this study, the investigators used deliberative processes for adapting the existing model of protein-energy wasting (PEW) to one that included stakeholder priorities, addressing gaps from the initial concept.
AHRQ-funded; HS023434.
Citation: Byham-Gray LD, Peters EN, Rothpletz-Puglia P .
Patient-centered model for protein-energy wasting: stakeholder deliberative panels.
J Ren Nutr 2020 Mar;30(2):137-44. doi: 10.1053/j.jrn.2019.06.001..
Keywords: Patient-Centered Healthcare, Patient-Centered Outcomes Research, Evidence-Based Practice, Patient and Family Engagement, Research Methodologies